FI20001108A - Menetelmä raseemisen cis-yhdisteen valmistamiseksi - Google Patents

Menetelmä raseemisen cis-yhdisteen valmistamiseksi Download PDF

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Publication number
FI20001108A
FI20001108A FI20001108A FI20001108A FI20001108A FI 20001108 A FI20001108 A FI 20001108A FI 20001108 A FI20001108 A FI 20001108A FI 20001108 A FI20001108 A FI 20001108A FI 20001108 A FI20001108 A FI 20001108A
Authority
FI
Finland
Prior art keywords
preparation
racemic cis
cis compound
compound
image
Prior art date
Application number
FI20001108A
Other languages
English (en)
Swedish (sv)
Inventor
Dennis M Godek
Charles W Murtiashaw
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI20001108A publication Critical patent/FI20001108A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Apparatuses For Bulk Treatment Of Fruits And Vegetables And Apparatuses For Preparing Feeds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Indole Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
FI20001108A 1991-01-03 2000-05-10 Menetelmä raseemisen cis-yhdisteen valmistamiseksi FI20001108A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/637,102 US5138060A (en) 1991-01-03 1991-01-03 Process and intermediates for preparing azabicyclo(2.2.2)octan-3-imines
PCT/US1991/009186 WO1992012152A1 (en) 1991-01-03 1991-12-18 Process and intermediates for preparing azabicyclo[2.2.2]octan-3-imines

Publications (1)

Publication Number Publication Date
FI20001108A true FI20001108A (fi) 2000-05-10

Family

ID=24554545

Family Applications (3)

Application Number Title Priority Date Filing Date
FI933065A FI933065A (fi) 1991-01-03 1993-07-02 Foerfarande foer framstaellning av azabicyklo (2.2.2)oktan-3-iminer och foerfarandet anvaenda mellanprodukter
FI20001108A FI20001108A (fi) 1991-01-03 2000-05-10 Menetelmä raseemisen cis-yhdisteen valmistamiseksi
FI20001109A FI20001109A (fi) 1991-01-03 2000-05-10 Menetelmä cis-yhdisteen raseemisen seoksen resolvoimiseksi

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI933065A FI933065A (fi) 1991-01-03 1993-07-02 Foerfarande foer framstaellning av azabicyklo (2.2.2)oktan-3-iminer och foerfarandet anvaenda mellanprodukter

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI20001109A FI20001109A (fi) 1991-01-03 2000-05-10 Menetelmä cis-yhdisteen raseemisen seoksen resolvoimiseksi

Country Status (21)

Country Link
US (1) US5138060A (fi)
EP (1) EP0565558B1 (fi)
JP (5) JPH0768244B1 (fi)
KR (1) KR970001157B1 (fi)
AT (1) ATE115580T1 (fi)
AU (1) AU653380B2 (fi)
CA (2) CA2098989C (fi)
DE (1) DE69106003T2 (fi)
DK (1) DK0565558T3 (fi)
ES (1) ES2065161T3 (fi)
FI (3) FI933065A (fi)
GR (1) GR3015021T3 (fi)
HU (1) HU9301931D0 (fi)
IE (1) IE65005B1 (fi)
IL (1) IL100541A0 (fi)
MX (1) MX9200003A (fi)
NO (1) NO932431D0 (fi)
NZ (1) NZ241161A (fi)
PT (1) PT99970B (fi)
WO (1) WO1992012152A1 (fi)
ZA (1) ZA928B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
ES2092113T3 (es) * 1991-06-20 1996-11-16 Pfizer Derivados fluoroalcoxibencilamino de heterociclos que contienen nitrogeno.
ES2111650T3 (es) * 1991-11-12 1998-03-16 Pfizer Derivados aciclicos de etilenodiamina como antagonistas de receptores de la sustancia p.
WO1993023380A1 (en) * 1992-05-18 1993-11-25 Pfizer Inc. Bridged aza-bicyclic derivatives as substance p antagonists
US5637699A (en) * 1992-06-29 1997-06-10 Merck & Co., Inc. Process for preparing morpholine tachykinin receptor antagonists
US6048859A (en) 1992-06-29 2000-04-11 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
US5719147A (en) * 1992-06-29 1998-02-17 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
US5688804A (en) * 1992-08-04 1997-11-18 Pfizer Inc. 3-Benzylamino-2-phenyl-piperidine derivatives as substance P receptor antagonists
US5387595A (en) * 1992-08-26 1995-02-07 Merck & Co., Inc. Alicyclic compounds as tachykinin receptor antagonists
US5518628A (en) * 1993-11-08 1996-05-21 Shipley Company Inc. Purification process
TW385308B (en) * 1994-03-04 2000-03-21 Merck & Co Inc Prodrugs of morpholine tachykinin receptor antagonists
US6861526B2 (en) 2002-10-16 2005-03-01 Pfizer Inc. Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine
US20050112695A1 (en) * 2003-10-27 2005-05-26 Meyer Donald W. Method of detecting bovine spongiform encephalopathy

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3560510A (en) * 1969-03-05 1971-02-02 Aldrich Chem Co Inc 2-benzhydrylquinuclidines
US3993652A (en) * 1973-07-09 1976-11-23 Air Products And Chemicals, Inc. Cyclic quaternary hydroxyalkyl phenoxide catalysts for isocyanate reactions
US4203990A (en) * 1979-04-30 1980-05-20 G. D. Searle & Co. Anti-diarrheal 2-substituted quinuclidines
FR2529548A1 (fr) * 1982-07-02 1984-01-06 Delalande Sa Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
JPS59110656A (ja) * 1982-12-15 1984-06-26 Hiroyuki Nohira 光学活性な１―フェニル―２―（パラ―トリル）エチルアミンの製造方法
DE3604591A1 (de) * 1986-02-14 1987-08-20 Degussa Verfahren zur herstellung chiraler glycinderivate
JPS6354342A (ja) * 1986-08-26 1988-03-08 Daicel Chem Ind Ltd （±）−α−エチルベンジルアミンの光学分割方法
JPS63145256A (ja) * 1986-12-09 1988-06-17 Nippon Kayaku Co Ltd 光学活性ホモフエニルアラニンの製造法及び中間体
MX18467A (es) * 1988-11-23 1993-07-01 Pfizer Agentes terapeuticos de quinuclidinas
EP0585328B1 (en) * 1991-05-22 2002-01-09 Pfizer Inc. Substituted 3-aminoquinuclidines

Also Published As

Publication number Publication date
JPH07316154A (ja) 1995-12-05
KR970001157B1 (ko) 1997-01-29
KR930703312A (ko) 1993-11-29
IE920001A1 (en) 1992-07-15
CA2158130A1 (en) 1992-07-04
DE69106003T2 (de) 1995-04-27
CA2158130C (en) 1998-07-14
ES2065161T3 (es) 1995-02-01
AU653380B2 (en) 1994-09-29
US5138060A (en) 1992-08-11
NO932431L (no) 1993-07-02
ZA928B (en) 1993-07-02
HU9301931D0 (en) 1993-12-28
DK0565558T3 (da) 1995-03-06
EP0565558B1 (en) 1994-12-14
CA2098989A1 (en) 1992-07-04
FI933065A0 (fi) 1993-07-02
IL100541A0 (en) 1992-09-06
JPH07316153A (ja) 1995-12-05
NZ241161A (en) 1994-10-26
DE69106003D1 (de) 1995-01-26
NO932431D0 (no) 1993-07-02
JPH0768244B1 (fi) 1995-07-26
FI20001109A (fi) 2000-05-10
ATE115580T1 (de) 1994-12-15
CA2098989C (en) 1998-02-03
PT99970B (pt) 1999-06-30
JP2845425B2 (ja) 1999-01-13
PT99970A (pt) 1993-02-26
AU9129891A (en) 1992-08-17
JPH05508867A (ja) 1993-12-09
FI933065A (fi) 1993-07-02
JPH07330766A (ja) 1995-12-19
IE65005B1 (en) 1995-10-04
WO1992012152A1 (en) 1992-07-23
EP0565558A1 (en) 1993-10-20
GR3015021T3 (en) 1995-05-31
JP2583026B2 (ja) 1997-02-19
JP2703193B2 (ja) 1998-01-26
MX9200003A (es) 1992-07-01

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Legal Events

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