ES2164258T3 - Procedimiento de preparacion de derivados de carbamoilmetilurea. - Google Patents

Procedimiento de preparacion de derivados de carbamoilmetilurea.

Info

Publication number
ES2164258T3
ES2164258T3 ES96925075T ES96925075T ES2164258T3 ES 2164258 T3 ES2164258 T3 ES 2164258T3 ES 96925075 T ES96925075 T ES 96925075T ES 96925075 T ES96925075 T ES 96925075T ES 2164258 T3 ES2164258 T3 ES 2164258T3
Authority
ES
Spain
Prior art keywords
carbamoilmetilurea
preparation procedure
derivatives preparation
derivatives
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96925075T
Other languages
English (en)
Inventor
Haruo Koike
Yasufumi Ueda
Koji Matsuda
Mikio Kabaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of ES2164258T3 publication Critical patent/ES2164258T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/22—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/18—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
    • C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
    • C07C273/1827—X being H
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

UN METODO PARA PREPARAR DERIVADOS DE CARBAMOILMETILUREA DE LA FORMULA (I): CARACTERIZADO POR REACCIONAR UN COMPUESTO DE LA FORMULA (II): CON UN COMPUESTO DE LA FORMULA (III):
ES96925075T 1995-08-07 1996-07-25 Procedimiento de preparacion de derivados de carbamoilmetilurea. Expired - Lifetime ES2164258T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20074995 1995-08-07

Publications (1)

Publication Number Publication Date
ES2164258T3 true ES2164258T3 (es) 2002-02-16

Family

ID=16429540

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96925075T Expired - Lifetime ES2164258T3 (es) 1995-08-07 1996-07-25 Procedimiento de preparacion de derivados de carbamoilmetilurea.

Country Status (12)

Country Link
US (1) US6015921A (es)
EP (1) EP0844236B1 (es)
KR (1) KR19990036236A (es)
CN (1) CN1197451A (es)
AT (1) ATE206109T1 (es)
AU (1) AU6530796A (es)
CA (1) CA2228622A1 (es)
DE (1) DE69615570T2 (es)
ES (1) ES2164258T3 (es)
PT (1) PT844236E (es)
TW (1) TW358087B (es)
WO (1) WO1997006135A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8183408B2 (en) 2007-11-16 2012-05-22 Kaneka Corporation Process for production of N-carbamoyl-tert-leucine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2928873A (en) * 1959-01-07 1960-03-15 U S Vitamin And Pharmaceutical Certain monoamides of hydantoic acid
EP0514442B1 (fr) * 1990-02-09 1994-04-27 Aventis Pharma S.A. N-phenyl n-acetamido glycinamides, leur preparation et les medicaments les contenant
FR2667864B2 (fr) * 1990-03-07 1994-08-05 Rhone Poulenc Sante Derives de n-phenyl glycinamides, leur preparation et les medicaments les contenant.
FR2659653B1 (fr) * 1990-03-13 1992-05-22 Rhone Poulenc Sante Derives de l'uree, leur preparation et les medicaments les contenant.
JP2877475B2 (ja) * 1990-09-10 1999-03-31 協和醗酵工業株式会社 ジチオールイリデン誘導体
RU2134684C1 (ru) * 1994-02-09 1999-08-20 Сионоги Энд Ко., Лтд. Производные карбамоилмочевины и фармацевтическая композиция

Also Published As

Publication number Publication date
PT844236E (pt) 2002-01-30
AU6530796A (en) 1997-03-05
US6015921A (en) 2000-01-18
TW358087B (en) 1999-05-11
EP0844236B1 (en) 2001-09-26
WO1997006135A1 (en) 1997-02-20
CN1197451A (zh) 1998-10-28
CA2228622A1 (en) 1997-02-20
KR19990036236A (ko) 1999-05-25
EP0844236A1 (en) 1998-05-27
DE69615570T2 (de) 2002-07-11
ATE206109T1 (de) 2001-10-15
EP0844236A4 (en) 1999-04-14
DE69615570D1 (de) 2001-10-31

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