ES2065161T3 - Procedimiento y productos intermedios para preparar azabiciclo(2.2.2)octan-3-iminas. - Google Patents

Procedimiento y productos intermedios para preparar azabiciclo(2.2.2)octan-3-iminas.

Info

Publication number
ES2065161T3
ES2065161T3 ES92901603T ES92901603T ES2065161T3 ES 2065161 T3 ES2065161 T3 ES 2065161T3 ES 92901603 T ES92901603 T ES 92901603T ES 92901603 T ES92901603 T ES 92901603T ES 2065161 T3 ES2065161 T3 ES 2065161T3
Authority
ES
Spain
Prior art keywords
iminas
azabiciclo
octan
prepare
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92901603T
Other languages
English (en)
Spanish (es)
Inventor
Dennis M Godek
Charles W Murtiashaw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Pfizer Corp SRL
Original Assignee
Pfizer Corp Belgium
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium, Pfizer Corp SRL filed Critical Pfizer Corp Belgium
Application granted granted Critical
Publication of ES2065161T3 publication Critical patent/ES2065161T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Indole Compounds (AREA)
  • Apparatuses For Bulk Treatment Of Fruits And Vegetables And Apparatuses For Preparing Feeds (AREA)
ES92901603T 1991-01-03 1991-12-18 Procedimiento y productos intermedios para preparar azabiciclo(2.2.2)octan-3-iminas. Expired - Lifetime ES2065161T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/637,102 US5138060A (en) 1991-01-03 1991-01-03 Process and intermediates for preparing azabicyclo(2.2.2)octan-3-imines

Publications (1)

Publication Number Publication Date
ES2065161T3 true ES2065161T3 (es) 1995-02-01

Family

ID=24554545

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92901603T Expired - Lifetime ES2065161T3 (es) 1991-01-03 1991-12-18 Procedimiento y productos intermedios para preparar azabiciclo(2.2.2)octan-3-iminas.

Country Status (21)

Country Link
US (1) US5138060A (enExample)
EP (1) EP0565558B1 (enExample)
JP (5) JPH0768244B1 (enExample)
KR (1) KR970001157B1 (enExample)
AT (1) ATE115580T1 (enExample)
AU (1) AU653380B2 (enExample)
CA (2) CA2098989C (enExample)
DE (1) DE69106003T2 (enExample)
DK (1) DK0565558T3 (enExample)
ES (1) ES2065161T3 (enExample)
FI (3) FI933065L (enExample)
GR (1) GR3015021T3 (enExample)
HU (1) HU9301931D0 (enExample)
IE (1) IE65005B1 (enExample)
IL (1) IL100541A0 (enExample)
MX (1) MX9200003A (enExample)
NO (1) NO932431L (enExample)
NZ (1) NZ241161A (enExample)
PT (1) PT99970B (enExample)
WO (1) WO1992012152A1 (enExample)
ZA (1) ZA928B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
BR9206161A (pt) * 1991-06-20 1995-10-31 Pfizer Derivados fluoroalcoxibenzilamino de heterociclos contendo nitrogénio
DK0613458T3 (da) * 1991-11-12 1998-02-09 Pfizer Acykliske ethylendiaminderivater som substans P receptorantagonister
CA2134964C (en) * 1992-05-18 1997-12-30 Manoj C. Desai Bridged aza-bicyclic derivatives as substance p antagonists
US5719147A (en) * 1992-06-29 1998-02-17 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
US6048859A (en) * 1992-06-29 2000-04-11 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
US5637699A (en) * 1992-06-29 1997-06-10 Merck & Co., Inc. Process for preparing morpholine tachykinin receptor antagonists
CA2141051A1 (en) * 1992-08-04 1994-02-17 Terry J. Rosen Substituted nitrogen-containing heterocycles
US5387595A (en) * 1992-08-26 1995-02-07 Merck & Co., Inc. Alicyclic compounds as tachykinin receptor antagonists
US5518628A (en) * 1993-11-08 1996-05-21 Shipley Company Inc. Purification process
IL112778A0 (en) * 1994-03-04 1995-05-26 Merck & Co Inc Substituted heterocycles, their preparation and pharmaceutical compositions containing them
US6861526B2 (en) 2002-10-16 2005-03-01 Pfizer Inc. Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine
US20050112695A1 (en) * 2003-10-27 2005-05-26 Meyer Donald W. Method of detecting bovine spongiform encephalopathy

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3560510A (en) * 1969-03-05 1971-02-02 Aldrich Chem Co Inc 2-benzhydrylquinuclidines
US3993652A (en) * 1973-07-09 1976-11-23 Air Products And Chemicals, Inc. Cyclic quaternary hydroxyalkyl phenoxide catalysts for isocyanate reactions
US4203990A (en) * 1979-04-30 1980-05-20 G. D. Searle & Co. Anti-diarrheal 2-substituted quinuclidines
FR2529548A1 (fr) * 1982-07-02 1984-01-06 Delalande Sa Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
JPS59110656A (ja) * 1982-12-15 1984-06-26 Hiroyuki Nohira 光学活性な１―フェニル―２―（パラ―トリル）エチルアミンの製造方法
DE3604591A1 (de) * 1986-02-14 1987-08-20 Degussa Verfahren zur herstellung chiraler glycinderivate
JPS6354342A (ja) * 1986-08-26 1988-03-08 Daicel Chem Ind Ltd （±）−α−エチルベンジルアミンの光学分割方法
JPS63145256A (ja) * 1986-12-09 1988-06-17 Nippon Kayaku Co Ltd 光学活性ホモフエニルアラニンの製造法及び中間体
MX18467A (es) * 1988-11-23 1993-07-01 Pfizer Agentes terapeuticos de quinuclidinas
RU2092486C1 (ru) * 1991-05-22 1997-10-10 Пфайзер Инк. Замещенные 3-аминохинуклидины

Also Published As

Publication number Publication date
JPH0768244B1 (enExample) 1995-07-26
FI933065A7 (fi) 1993-07-02
JPH07316153A (ja) 1995-12-05
US5138060A (en) 1992-08-11
FI20001108A7 (fi) 2000-05-10
JP2845425B2 (ja) 1999-01-13
IE920001A1 (en) 1992-07-15
HU9301931D0 (en) 1993-12-28
CA2098989C (en) 1998-02-03
NO932431D0 (no) 1993-07-02
ATE115580T1 (de) 1994-12-15
JPH07330766A (ja) 1995-12-19
AU653380B2 (en) 1994-09-29
IE65005B1 (en) 1995-10-04
FI20001109L (fi) 2000-05-10
KR930703312A (ko) 1993-11-29
CA2158130A1 (en) 1992-07-04
DE69106003T2 (de) 1995-04-27
JPH05508867A (ja) 1993-12-09
FI20001109A7 (fi) 2000-05-10
NO932431L (no) 1993-07-02
JPH0768244B2 (ja) 1995-07-26
IL100541A0 (en) 1992-09-06
FI20001108L (fi) 2000-05-10
NZ241161A (en) 1994-10-26
JPH07316154A (ja) 1995-12-05
KR970001157B1 (ko) 1997-01-29
WO1992012152A1 (en) 1992-07-23
PT99970A (pt) 1993-02-26
ZA928B (en) 1993-07-02
FI933065A0 (fi) 1993-07-02
JP2583026B2 (ja) 1997-02-19
EP0565558B1 (en) 1994-12-14
AU9129891A (en) 1992-08-17
DK0565558T3 (da) 1995-03-06
PT99970B (pt) 1999-06-30
EP0565558A1 (en) 1993-10-20
FI933065L (fi) 1993-07-02
DE69106003D1 (de) 1995-01-26
GR3015021T3 (en) 1995-05-31
CA2158130C (en) 1998-07-14
CA2098989A1 (en) 1992-07-04
MX9200003A (es) 1992-07-01
JP2703193B2 (ja) 1998-01-26

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