FI931613A - Acylaminoindolderivat - Google Patents

Acylaminoindolderivat Download PDF

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Publication number
FI931613A
FI931613A FI931613A FI931613A FI931613A FI 931613 A FI931613 A FI 931613A FI 931613 A FI931613 A FI 931613A FI 931613 A FI931613 A FI 931613A FI 931613 A FI931613 A FI 931613A
Authority
FI
Finland
Prior art keywords
aryl
alkyl
alkylaryl
hydrogen
pct
Prior art date
Application number
FI931613A
Other languages
English (en)
Other versions
FI931613A0 (fi
FI111256B (fi
Inventor
John E Macor
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI931613A0 publication Critical patent/FI931613A0/fi
Publication of FI931613A publication Critical patent/FI931613A/fi
Application granted granted Critical
Publication of FI111256B publication Critical patent/FI111256B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Materials For Photolithography (AREA)
  • Soft Magnetic Materials (AREA)
  • Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
FI931613A 1992-04-10 1993-04-08 Menetelmä terapeuttisesti käyttökelpoisten asyyliaminoindolijohdannaisten valmistamiseksi FI111256B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86638292A 1992-04-10 1992-04-10
US86638292 1992-04-10

Publications (3)

Publication Number Publication Date
FI931613A0 FI931613A0 (fi) 1993-04-08
FI931613A true FI931613A (fi) 1993-10-11
FI111256B FI111256B (fi) 2003-06-30

Family

ID=25347493

Family Applications (2)

Application Number Title Priority Date Filing Date
FI931613A FI111256B (fi) 1992-04-10 1993-04-08 Menetelmä terapeuttisesti käyttökelpoisten asyyliaminoindolijohdannaisten valmistamiseksi
FI20010214A FI20010214A (fi) 1992-04-10 2001-02-05 Asyyliaminoindolijohdannaisia

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI20010214A FI20010214A (fi) 1992-04-10 2001-02-05 Asyyliaminoindolijohdannaisia

Country Status (31)

Country Link
US (1) US5498626A (fi)
EP (1) EP0635015B1 (fi)
JP (1) JP2544704B2 (fi)
KR (1) KR0179074B1 (fi)
CN (1) CN1038506C (fi)
AT (1) ATE148465T1 (fi)
AU (1) AU670270B2 (fi)
BR (1) BR9306221A (fi)
CA (1) CA2132706C (fi)
CZ (1) CZ282653B6 (fi)
DE (1) DE69307875T2 (fi)
DK (1) DK0635015T3 (fi)
EG (1) EG20466A (fi)
ES (1) ES2097496T3 (fi)
FI (2) FI111256B (fi)
GR (1) GR3022767T3 (fi)
HR (1) HRP930753B1 (fi)
HU (1) HUT64060A (fi)
IL (1) IL105309A0 (fi)
MX (1) MX9301996A (fi)
MY (1) MY115278A (fi)
NO (1) NO309860B1 (fi)
NZ (1) NZ251047A (fi)
PL (1) PL172232B1 (fi)
RU (1) RU2110516C1 (fi)
SK (1) SK278182B6 (fi)
TW (1) TW394769B (fi)
UA (1) UA34452C2 (fi)
WO (1) WO1993021180A1 (fi)
YU (1) YU48916B (fi)
ZA (1) ZA932536B (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5559246A (en) * 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
US5559129A (en) * 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5607951A (en) * 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
US6380233B1 (en) 1992-04-07 2002-04-30 Pfizer Inc Indole derivatives as 5-HT1 agonists
CZ281763B6 (cs) 1992-04-07 1997-01-15 Pfizer Inc. Indolové deriváty představující 5-HT1 agonisty, způsob jejich přípravy, farmaceutické prostředky obsahující tyto látky, jejich použití a meziprodukty postupu přípravy
ES2070772B1 (es) * 1993-08-09 1996-02-16 Pfizer Derivados de acilaminoindol
HUT75646A (en) * 1993-08-31 1997-05-28 Pfizer 5-arylindole derivatives and pharmaceutical compositions containing them
GB9402016D0 (en) * 1994-02-02 1994-03-30 Merck Sharp & Dohme Therapeutic agents
GB9402011D0 (en) * 1994-02-02 1994-03-30 Merck Sharp & Dohme Therapeutic agents
AU3162695A (en) * 1994-08-03 1996-03-04 Asta Medica Aktiengesellschaft Indol, indazol, pyridopyrrol and pyridopyrazol derivatives with anti-asthmatic, anti-allergic, anti-inflammatory and immunomodulating effects
GB9417310D0 (en) 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
GB9420503D0 (en) * 1994-10-11 1994-11-23 Pfizer Ltd Therapeutic agents
GB9420529D0 (en) 1994-10-12 1994-11-30 Pfizer Ltd Indoles
AU3170099A (en) * 1998-04-16 1999-11-08 Yamanouchi Pharmaceutical Co., Ltd. Remedies for obesity
US5994352A (en) * 1998-11-13 1999-11-30 Pfizer Inc. 5-arylindole derivatives
JP2006516286A (ja) * 2003-01-22 2006-06-29 ジーティーエックス・インコーポレイテッド Ｓａｒｍによる女性のアンドロゲン減少に関連する病気の治療
CA2708043C (en) * 2007-12-07 2012-11-13 Pfizer Inc. Tosylate salt of trans-n-isobutyl-3-fluoro-3- [3-fluoro-4- (pyrrolidin-1-yl-methyl) -phenyl] cyclobut anecarboxamide
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia
CN103408535B (zh) * 2013-08-13 2016-03-02 张家港威胜生物医药有限公司 一种依来曲普坦中间体-5-溴-3-(n-甲基吡咯啉-2-基甲基)-1h-吲哚合成工艺

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
ZA815541B (en) * 1980-08-12 1983-03-30 Glaxo Group Ltd Heterocyclic compounds
AU550010B2 (en) * 1980-08-12 1986-02-27 Glaxo Group Limited 5-tryptaminoacetamides, carbamates and ureas
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
GB8724912D0 (en) * 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
IL96891A0 (en) * 1990-01-17 1992-03-29 Merck Sharp & Dohme Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them
CA2042295A1 (fr) * 1990-05-15 1991-11-16 Jacques Chauveau Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
CA2064815C (en) * 1990-06-07 1999-11-16 Alan Duncan Robertson Therapeutic heterocyclic compounds
AU651637B2 (en) * 1990-10-15 1994-07-28 Pfizer Inc. Indole derivatives
US5208248A (en) * 1991-01-11 1993-05-04 Merck Sharpe & Dohme, Ltd. Indazole-substituted five-membered heteroaromatic compounds
SK278998B6 (sk) * 1991-02-01 1998-05-06 Merck Sharp & Dohme Limited Deriváty imidazolu, triazolu a tetrazolu, spôsob i
HUT69705A (en) * 1991-11-25 1995-09-28 Pfizer Indole derivatives

Also Published As

Publication number Publication date
CZ282653B6 (cs) 1997-08-13
EG20466A (en) 1999-05-31
WO1993021180A1 (en) 1993-10-28
US5498626A (en) 1996-03-12
FI931613A0 (fi) 1993-04-08
AU670270B2 (en) 1996-07-11
FI20010214A (fi) 2001-02-05
DE69307875T2 (de) 1997-05-22
GR3022767T3 (en) 1997-06-30
HUT64060A (en) 1993-11-29
RU2110516C1 (ru) 1998-05-10
HRP930753B1 (en) 2000-10-31
HU9301048D0 (en) 1993-06-28
HRP930753A2 (en) 1994-10-31
RU94045902A (ru) 1996-08-27
ATE148465T1 (de) 1997-02-15
MX9301996A (es) 1994-03-31
JPH07501831A (ja) 1995-02-23
EP0635015B1 (en) 1997-01-29
SK278182B6 (en) 1996-03-06
AU3782193A (en) 1993-11-18
CA2132706A1 (en) 1993-10-28
TW394769B (en) 2000-06-21
JP2544704B2 (ja) 1996-10-16
ZA932536B (en) 1994-10-08
FI111256B (fi) 2003-06-30
PL172232B1 (pl) 1997-08-29
EP0635015A1 (en) 1995-01-25
BR9306221A (pt) 1998-06-30
NZ251047A (en) 1996-09-25
YU48916B (sh) 2002-11-15
NO943803D0 (no) 1994-10-07
DE69307875D1 (de) 1997-03-13
KR0179074B1 (ko) 1999-03-20
ES2097496T3 (es) 1997-04-01
YU25593A (sh) 1996-10-09
CN1038506C (zh) 1998-05-27
MY115278A (en) 2003-05-31
DK0635015T3 (da) 1997-03-17
NO309860B1 (no) 2001-04-09
UA34452C2 (uk) 2001-03-15
IL105309A0 (en) 1993-08-18
CN1080288A (zh) 1994-01-05
NO943803L (no) 1994-10-07
CA2132706C (en) 1998-08-04
KR950700903A (ko) 1995-02-20
CZ247794A3 (en) 1995-07-12
SK120794A3 (en) 1995-05-10

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Legal Events

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MA Patent expired