EG20466A - Process for preparing of acylaminoindole derivatives - Google Patents

Process for preparing of acylaminoindole derivatives

Info

Publication number
EG20466A
EG20466A EG21493A EG21493A EG20466A EG 20466 A EG20466 A EG 20466A EG 21493 A EG21493 A EG 21493A EG 21493 A EG21493 A EG 21493A EG 20466 A EG20466 A EG 20466A
Authority
EG
Egypt
Prior art keywords
aryl
alkyl
alkylaryl
hydrogen
pct
Prior art date
Application number
EG21493A
Other languages
English (en)
Inventor
John A Macor
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of EG20466A publication Critical patent/EG20466A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Materials For Photolithography (AREA)
  • Soft Magnetic Materials (AREA)
  • Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EG21493A 1992-04-10 1993-04-07 Process for preparing of acylaminoindole derivatives EG20466A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86638292A 1992-04-10 1992-04-10

Publications (1)

Publication Number Publication Date
EG20466A true EG20466A (en) 1999-05-31

Family

ID=25347493

Family Applications (1)

Application Number Title Priority Date Filing Date
EG21493A EG20466A (en) 1992-04-10 1993-04-07 Process for preparing of acylaminoindole derivatives

Country Status (31)

Country Link
US (1) US5498626A (xx)
EP (1) EP0635015B1 (xx)
JP (1) JP2544704B2 (xx)
KR (1) KR0179074B1 (xx)
CN (1) CN1038506C (xx)
AT (1) ATE148465T1 (xx)
AU (1) AU670270B2 (xx)
BR (1) BR9306221A (xx)
CA (1) CA2132706C (xx)
CZ (1) CZ282653B6 (xx)
DE (1) DE69307875T2 (xx)
DK (1) DK0635015T3 (xx)
EG (1) EG20466A (xx)
ES (1) ES2097496T3 (xx)
FI (2) FI111256B (xx)
GR (1) GR3022767T3 (xx)
HR (1) HRP930753B1 (xx)
HU (1) HUT64060A (xx)
IL (1) IL105309A0 (xx)
MX (1) MX9301996A (xx)
MY (1) MY115278A (xx)
NO (1) NO309860B1 (xx)
NZ (1) NZ251047A (xx)
PL (1) PL172232B1 (xx)
RU (1) RU2110516C1 (xx)
SK (1) SK278182B6 (xx)
TW (1) TW394769B (xx)
UA (1) UA34452C2 (xx)
WO (1) WO1993021180A1 (xx)
YU (1) YU48916B (xx)
ZA (1) ZA932536B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5559246A (en) * 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
US5559129A (en) * 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
US5607951A (en) * 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
UA27467C2 (uk) 1992-04-07 2000-09-15 Пфайзер Інк. ПОХІДНІ ІНДОЛУ ЯК 5-НТ<sub>1</sub> АГОНІСТИ ТА ПРОМІЖНІ СПОЛУКИ
US6380233B1 (en) 1992-04-07 2002-04-30 Pfizer Inc Indole derivatives as 5-HT1 agonists
ES2070772B1 (es) * 1993-08-09 1996-02-16 Pfizer Derivados de acilaminoindol
US5849739A (en) * 1993-08-31 1998-12-15 Pfizer Inc. 5-arylindole derivatives
GB9402011D0 (en) * 1994-02-02 1994-03-30 Merck Sharp & Dohme Therapeutic agents
GB9402016D0 (en) * 1994-02-02 1994-03-30 Merck Sharp & Dohme Therapeutic agents
US5965582A (en) * 1994-08-03 1999-10-12 Asta Medica Aktiengesellschaft N-benzylindole and benzopyrazole derivatives with anti-asthmatic, anti-allergic, anti-inflammatory and immunemodulating effect
GB9417310D0 (en) 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
GB9420503D0 (en) * 1994-10-11 1994-11-23 Pfizer Ltd Therapeutic agents
GB9420529D0 (en) 1994-10-12 1994-11-30 Pfizer Ltd Indoles
WO1999053956A1 (fr) * 1998-04-16 1999-10-28 Yamanouchi Pharmaceutical Co., Ltd. Remedes contre l'obesite
US5994352A (en) * 1998-11-13 1999-11-30 Pfizer Inc. 5-arylindole derivatives
AU2004206909A1 (en) * 2003-01-22 2004-08-05 Gtx Inc. Treating androgen deficiency in female (ADIF)-associated conditions with sarms
RU2451016C2 (ru) * 2007-12-07 2012-05-20 Пфайзер Инк. Тозилатная соль транс-n-изобутил-3-фтор-3-[3-фтор-4-(пирролидин-1-илметил)фенил]циклобутанкарбоксамида
EP2919788A4 (en) 2012-11-14 2016-05-25 Univ Johns Hopkins METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA
CN103408535B (zh) * 2013-08-13 2016-03-02 张家港威胜生物医药有限公司 一种依来曲普坦中间体-5-溴-3-(n-甲基吡咯啉-2-基甲基)-1h-吲哚合成工艺

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
BE889931A (fr) * 1980-08-12 1982-02-11 Glaxo Group Ltd Derives indoliques, leur preparation et leurs applications en tant que medicaments
ES504694A0 (es) * 1980-08-12 1982-11-01 Glaxo Group Ltd Procedimiento para la preparacion de derivados del indol.
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
GB8724912D0 (en) * 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
IL96891A0 (en) * 1990-01-17 1992-03-29 Merck Sharp & Dohme Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them
CA2042295A1 (fr) * 1990-05-15 1991-11-16 Jacques Chauveau Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
MC2210A1 (fr) * 1990-06-07 1992-11-26 Wellcome Found Composes heterocycliques therapeutiques,leur utilisation et procede pour les preparer
DE9190141U1 (de) * 1990-10-15 1993-07-15 Pfizer Inc., New York, N.Y. Indolderivate
US5208248A (en) * 1991-01-11 1993-05-04 Merck Sharpe & Dohme, Ltd. Indazole-substituted five-membered heteroaromatic compounds
CZ283018B6 (cs) * 1991-02-01 1997-12-17 Merck Sharp And Dohme Limited Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
ES2143992T3 (es) * 1991-11-25 2000-06-01 Pfizer Derivados de 5-(hetero- o carbociclilamino)-indol, su preparacion y uso como 5-ht1 agonistas.

Also Published As

Publication number Publication date
FI931613A (fi) 1993-10-11
ES2097496T3 (es) 1997-04-01
FI931613A0 (fi) 1993-04-08
ATE148465T1 (de) 1997-02-15
KR950700903A (ko) 1995-02-20
CN1038506C (zh) 1998-05-27
EP0635015A1 (en) 1995-01-25
HUT64060A (en) 1993-11-29
CZ282653B6 (cs) 1997-08-13
FI20010214A (fi) 2001-02-05
WO1993021180A1 (en) 1993-10-28
GR3022767T3 (en) 1997-06-30
NO943803L (no) 1994-10-07
CZ247794A3 (en) 1995-07-12
SK120794A3 (en) 1995-05-10
ZA932536B (en) 1994-10-08
DE69307875T2 (de) 1997-05-22
DK0635015T3 (da) 1997-03-17
EP0635015B1 (en) 1997-01-29
DE69307875D1 (de) 1997-03-13
JP2544704B2 (ja) 1996-10-16
MX9301996A (es) 1994-03-31
PL172232B1 (pl) 1997-08-29
SK278182B6 (en) 1996-03-06
UA34452C2 (uk) 2001-03-15
NO943803D0 (no) 1994-10-07
TW394769B (en) 2000-06-21
CA2132706C (en) 1998-08-04
CN1080288A (zh) 1994-01-05
HU9301048D0 (en) 1993-06-28
FI111256B (fi) 2003-06-30
RU94045902A (ru) 1996-08-27
BR9306221A (pt) 1998-06-30
HRP930753A2 (en) 1994-10-31
JPH07501831A (ja) 1995-02-23
YU25593A (sh) 1996-10-09
AU3782193A (en) 1993-11-18
YU48916B (sh) 2002-11-15
RU2110516C1 (ru) 1998-05-10
MY115278A (en) 2003-05-31
IL105309A0 (en) 1993-08-18
KR0179074B1 (ko) 1999-03-20
AU670270B2 (en) 1996-07-11
CA2132706A1 (en) 1993-10-28
NO309860B1 (no) 2001-04-09
NZ251047A (en) 1996-09-25
HRP930753B1 (en) 2000-10-31
US5498626A (en) 1996-03-12

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