FI924054A7 - Imidatsoliin liitetyt iso- ja heterosyklit, menetelmä niiden valmistamiseksi ja niiden käyttö - Google Patents

Imidatsoliin liitetyt iso- ja heterosyklit, menetelmä niiden valmistamiseksi ja niiden käyttö Download PDF

Info

Publication number
FI924054A7
FI924054A7 FI924054A FI924054A FI924054A7 FI 924054 A7 FI924054 A7 FI 924054A7 FI 924054 A FI924054 A FI 924054A FI 924054 A FI924054 A FI 924054A FI 924054 A7 FI924054 A7 FI 924054A7
Authority
FI
Finland
Prior art keywords
heterocycles
imidazole
preparation
iso
linked
Prior art date
Application number
FI924054A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI924054A0 (fi
FI924054L (fi
Inventor
Bernward Schölkens
Hermann Gerhards
Holger Heitsch
Adalbert Wagner
Heinz-Werner Kleemann
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19914131325 external-priority patent/DE4131325A1/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI924054A0 publication Critical patent/FI924054A0/fi
Publication of FI924054L publication Critical patent/FI924054L/fi
Publication of FI924054A7 publication Critical patent/FI924054A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Detergent Compositions (AREA)
  • Lubricants (AREA)
  • Pyridine Compounds (AREA)
FI924054A 1991-09-14 1992-09-10 Imidatsoliin liitetyt iso- ja heterosyklit, menetelmä niiden valmistamiseksi ja niiden käyttö FI924054A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4130659 1991-09-14
DE19914131325 DE4131325A1 (de) 1991-09-20 1991-09-20 Imidazo-annellierte iso und heterocyclen, verfahren zu deren herstellung, sie enthaltende mittel und ihre verwendung

Publications (3)

Publication Number Publication Date
FI924054A0 FI924054A0 (fi) 1992-09-10
FI924054L FI924054L (fi) 1993-03-15
FI924054A7 true FI924054A7 (fi) 1993-03-15

Family

ID=25907347

Family Applications (1)

Application Number Title Priority Date Filing Date
FI924054A FI924054A7 (fi) 1991-09-14 1992-09-10 Imidatsoliin liitetyt iso- ja heterosyklit, menetelmä niiden valmistamiseksi ja niiden käyttö

Country Status (22)

Country Link
US (2) US5444068A (enExample)
EP (1) EP0533058B1 (enExample)
JP (1) JP3459659B2 (enExample)
KR (1) KR930006020A (enExample)
CN (1) CN1070646A (enExample)
AT (1) ATE247644T1 (enExample)
AU (1) AU659485B2 (enExample)
BR (1) BR9203543A (enExample)
CA (1) CA2078058A1 (enExample)
CZ (1) CZ280492A3 (enExample)
DE (1) DE59209986D1 (enExample)
DK (1) DK0533058T3 (enExample)
ES (1) ES2204888T3 (enExample)
FI (1) FI924054A7 (enExample)
HU (1) HUT62892A (enExample)
IL (1) IL103141A0 (enExample)
NO (1) NO300326B1 (enExample)
NZ (1) NZ244303A (enExample)
PL (1) PL171766B1 (enExample)
PT (1) PT533058E (enExample)
RU (1) RU2076105C1 (enExample)
TW (1) TW300219B (enExample)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223499A (en) * 1989-05-30 1993-06-29 Merck & Co., Inc. 6-amino substituted imidazo[4,5-bipyridines as angiotensin II antagonists
US5210092A (en) * 1990-09-25 1993-05-11 Fujisawa Pharmaceutical Co., Ltd. Angiotensin ii antagonizing heterocyclic derivatives
CA2062558A1 (en) * 1991-03-08 1992-09-09 Prasun K. Chakravarty Heterocyclic compounds bearing acidic functional groups as angiotensin ii antagonists
NZ254112A (en) * 1992-07-10 1997-06-24 Boots Co Plc Dioxocyclobutene derivatives; compounds, preparation and pharmaceutical compositions
TW348175B (en) * 1993-01-06 1998-12-21 Hoechst Ag Process for the preparation of biphenyl derivatives
CA2125251C (en) * 1993-06-07 2005-04-26 Yoshiyuki Inada A pharmaceutical composition for angiotensin ii-mediated diseases
US5571813A (en) * 1993-06-10 1996-11-05 Beiersdorf-Lilly Gmbh Fused pyrimidine compounds and their use as pharmaceuticals
EP0628559B1 (en) * 1993-06-10 2002-04-03 Beiersdorf-Lilly GmbH Pyrimidine compounds and their use as pharmaceuticals
DE4320432A1 (de) * 1993-06-21 1994-12-22 Bayer Ag Substituierte Mono- und Bipyridylmethylderivate
FR2708612B1 (fr) * 1993-08-05 1996-03-01 Roussel Uclaf Nouveaux dérivés bicycliques de l'imidazole, leur procédé de préparation, les nouveaux intermédiaires obtenus, leur application à titre de médicaments et les compositions pharmaceutiques les renfermant.
WO1996004270A1 (en) 1994-08-04 1996-02-15 Synaptic Pharmaceutical Corporation Novel benzimidazole derivatives
EP0849549B1 (en) * 1996-12-18 2002-04-24 Showa Denko Kabushiki Kaisha Accumulator
US6495583B1 (en) 1997-03-25 2002-12-17 Synaptic Pharmaceutical Corporation Benzimidazole derivatives
PL191111B1 (pl) * 1997-04-24 2006-03-31 Ortho Mcneil Pharm Inc Podstawione imidazole, sposób ich wytwarzania, kompozycje zawierające podstawione imidazole oraz ich zastosowanie
EP0994877A1 (en) 1997-07-03 2000-04-26 Du Pont Pharmaceuticals Company Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders
PL340711A1 (en) * 1997-11-24 2001-02-26 Procter & Gamble Derivatives of 5-(2-imidazolinamino)-benzimidazole, their production and application of them as antagonists of alpha-adrenergic receptors of improved metabolic stability
US6124463A (en) * 1998-07-02 2000-09-26 Dupont Pharmaceuticals Benzimidazoles as corticotropin release factor antagonists
US6365589B1 (en) 1998-07-02 2002-04-02 Bristol-Myers Squibb Pharma Company Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists
US20050267148A1 (en) * 1998-07-15 2005-12-01 Teijin Limited Benzimidazole derivative
EE04904B1 (et) 1998-07-15 2007-10-15 Teijin Limited Tiobensimidasooli derivaadid ja farmatseutiline kompositsioon
EP1117966A1 (en) * 1998-09-29 2001-07-25 Stanhope Products Company Self-positioning adsorbent package for air conditioning accumulators
US6331539B1 (en) * 1999-06-10 2001-12-18 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines
US6279341B1 (en) * 1999-07-01 2001-08-28 Multisorb Technologies, Inc. Self-retaining adsorbent unit
GB9919778D0 (en) * 1999-08-21 1999-10-27 Zeneca Ltd Chemical compounds
EP1167360A1 (en) * 2000-01-17 2002-01-02 Teijin Limited Human chymase inhibitors
WO2003064414A1 (en) * 2002-01-29 2003-08-07 Vicore Pharma Ab. Tricyclic compounds useful as angiotensin ii agonists
EP1546143A1 (en) * 2002-09-17 2005-06-29 Warner-Lambert Company LLC Heterocyclic substituted piperazines for the treatment of schizophrenia
US20040102360A1 (en) * 2002-10-30 2004-05-27 Barnett Stanley F. Combination therapy
AU2004266641A1 (en) 2003-08-12 2005-03-03 3M Innovative Properties Company Oxime substituted imidazo-containing compounds
EP1658076B1 (en) 2003-08-27 2013-03-06 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted imidazoquinolines
US20050054665A1 (en) 2003-09-05 2005-03-10 3M Innovative Properties Company Treatment for CD5+ B cell lymphoma
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
ES2544477T3 (es) 2003-10-03 2015-08-31 3M Innovative Properties Company Imidazoquinolinas sustituidas con alcoxi
US7897767B2 (en) 2003-11-14 2011-03-01 3M Innovative Properties Company Oxime substituted imidazoquinolines
JP2007511535A (ja) 2003-11-14 2007-05-10 スリーエム イノベイティブ プロパティズ カンパニー ヒドロキシルアミン置換イミダゾ環化合物
RU2409576C2 (ru) 2003-11-25 2011-01-20 3М Инновейтив Пропертиз Компани Системы, содержащие имидазольное кольцо с заместителями, и способы их получения
WO2005066170A1 (en) 2003-12-29 2005-07-21 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
CA2551399A1 (en) 2003-12-30 2005-07-21 3M Innovative Properties Company Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
EP1730143A2 (en) 2004-03-24 2006-12-13 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
WO2005123080A2 (en) 2004-06-15 2005-12-29 3M Innovative Properties Company Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
WO2006065280A2 (en) 2004-06-18 2006-06-22 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
WO2006009826A1 (en) 2004-06-18 2006-01-26 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
WO2006038923A2 (en) 2004-06-18 2006-04-13 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
CA2592904C (en) 2004-12-30 2015-04-07 3M Innovative Properties Company Chiral fused [1,2]imidazo[4,5-c] ring compounds
AU2005326708C1 (en) 2004-12-30 2012-08-30 3M Innovative Properties Company Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
US9248127B2 (en) 2005-02-04 2016-02-02 3M Innovative Properties Company Aqueous gel formulations containing immune response modifiers
WO2006086634A2 (en) 2005-02-11 2006-08-17 Coley Pharmaceutical Group, Inc. Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
AU2006232375A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
US7943610B2 (en) 2005-04-01 2011-05-17 3M Innovative Properties Company Pyrazolopyridine-1,4-diamines and analogs thereof
US7906506B2 (en) 2006-07-12 2011-03-15 3M Innovative Properties Company Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
JP5546451B2 (ja) 2007-06-04 2014-07-09 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸の障害、炎症、癌および他の障害の処置に有用なグアニル酸シクラーゼのアゴニスト
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP3241839B1 (en) 2008-07-16 2019-09-04 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
HK1220696A1 (zh) 2013-03-15 2017-05-12 Bausch Health Ireland Limited 鸟苷酸环化酶激动剂及其用途
EP4424697A3 (en) 2013-06-05 2024-12-25 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase c, method of making and using same
WO2016100184A1 (en) 2014-12-16 2016-06-23 Forum Pharmaceuticals, Inc. Geminal substituted quinuclidine amide compounds as agonists of alpha-7 nicotinic acetylcholine receptors
JP2018516973A (ja) 2015-06-10 2018-06-28 フォーラム・ファーマシューティカルズ・インコーポレイテッドＦｏｒｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． α７−ニコチン性アセチルコリン受容体のアゴニストとしてのアミノベンゾイソオキサゾール化合物
EP3334740A4 (en) 2015-08-12 2019-02-06 Axovant Sciences GmbH GEMINAL SUBSTITUTED AMINOBENZISOXAZOLE COMPOUNDS AS AGONISTS OF ALPHA 7-NICOTINIC ACETYLCHOLINE RECEPTORS
KR102419223B1 (ko) * 2021-11-16 2022-07-08 세진산업(주) 수소유기균열 방지를 위한 초고압 배관
KR102643639B1 (ko) * 2023-02-20 2024-03-05 (주) 범강기연 무용접 가스 파이프 연결 구조 및 방법

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4612323A (en) * 1983-06-27 1986-09-16 Sumitomo Chemical Company, Limited Insecticidal and acaricidal derivatives of 1-benzylbenzimidazole
IT1173196B (it) * 1984-02-02 1987-06-18 Bellon Roger Schoum Rbs Pharma Composti imidazopiridinici farmacologicamente attivi
JPS61151176A (ja) * 1984-12-24 1986-07-09 Sumitomo Chem Co Ltd ベンズイミダゾール誘導体およびそれを有効成分とする殺虫、殺ダニ剤
US4728741A (en) * 1985-01-08 1988-03-01 Smithkline Beckman Corporation 1-substituted-2-mercapto benzimidazole compounds and intermediates
US4880804A (en) * 1988-01-07 1989-11-14 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking benzimidazoles
JPH0273071A (ja) * 1988-09-09 1990-03-13 Sumitomo Chem Co Ltd ベンズイミダゾール誘導体、その製造法およびそれを有効成分とする殺虫、殺ダニ剤
GB8904174D0 (en) * 1989-02-23 1989-04-05 British Bio Technology Compounds
DE3928177A1 (de) * 1989-04-08 1991-02-28 Thomae Gmbh Dr K Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
CA2016710A1 (en) * 1989-05-15 1990-11-15 Prasun K. Chakravarty Substituted benzimidazoles as angiotensin ii antagonists
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
IL94390A (en) * 1989-05-30 1996-03-31 Merck & Co Inc The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them
US5102880A (en) * 1989-05-30 1992-04-07 Merck & Co., Inc. Substituted imidazo-fused 6-membered heterocycles as angiotensin II antagonists
US5223499A (en) * 1989-05-30 1993-06-29 Merck & Co., Inc. 6-amino substituted imidazo[4,5-bipyridines as angiotensin II antagonists
US5298518A (en) * 1989-09-29 1994-03-29 Eisai Co., Ltd. Biphenylmethane derivative and pharmacological use
IE70593B1 (en) * 1989-09-29 1996-12-11 Eisai Co Ltd Biphenylmethane derivative the use of it and pharmacological compositions containing same
IL95975A (en) * 1989-10-24 1997-06-10 Takeda Chemical Industries Ltd N-benzyl- 2-alkylbenzimidazole derivatives, their production and pharmaceutical compositions containing them
JPH03223281A (ja) * 1989-12-01 1991-10-02 Glaxo Group Ltd ベンゾチオフェン誘導体
GB8927277D0 (en) * 1989-12-01 1990-01-31 Glaxo Group Ltd Chemical compounds
FR2658511B1 (fr) * 1990-02-16 1992-06-19 Union Pharma Scient Appl Nouveaux derives de benzimidazole et d'azabenzimidazole, antagonistes des recepteurs au thromboxane; leurs procedes de preparation, compositions pharmaceutiques les contenant.
AU653524B2 (en) * 1990-06-08 1994-10-06 Roussel-Uclaf New imidazole derivatives, their preparation process, the new intermediates obtained, their use as medicaments and the pharmaceutical compositions containing them
AU7820091A (en) * 1990-06-08 1991-12-12 Roussel-Uclaf New benzimidazole derivatives, their preparation process, the new intermediates obtained, their use as medicaments and the pharmaceutical compositions containing them
EP0470543A1 (de) * 1990-08-10 1992-02-12 Dr. Karl Thomae GmbH Heterocyclische Imidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zur ihrer Herstellung
DE4025359A1 (de) * 1990-08-10 1992-02-13 Triumph Adler Ag Verfahren zur einstellung der abdruckenergie einer type und schreibmaschine, drucker o. dgl. zur durchfuehrung des verfahrens
US5087702A (en) * 1991-01-30 1992-02-11 Merck & Co., Inc. Microbial transformation process for producing an antihypertensive product
US5177074A (en) * 1991-03-26 1993-01-05 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted thiophene or furan
US5158327A (en) * 1991-10-11 1992-10-27 Neil Rowe Hydraulic hose coupling handle and method of making same
US5376666A (en) * 1992-11-30 1994-12-27 The Du Pont Merck Pharmaceutical Company Angiotension-II receptor blocking, azacycloalkyl or azacycloalkenyl
DE4304455A1 (de) * 1993-02-15 1994-08-18 Bayer Ag Heterocyclisch substituierte Phenyl-cyclohexan-carbonsäurederivate
US5395844A (en) * 1993-06-10 1995-03-07 The Du Pont Merck Pharmaceutical Company Imidazole 5-position substituted angiotensin II antagonists

Also Published As

Publication number Publication date
ATE247644T1 (de) 2003-09-15
BR9203543A (pt) 1993-04-13
HUT62892A (en) 1993-06-28
AU659485B2 (en) 1995-05-18
US5635525A (en) 1997-06-03
CZ280492A3 (en) 1993-04-14
DK0533058T3 (da) 2003-11-24
PT533058E (pt) 2004-01-30
DE59209986D1 (de) 2003-09-25
FI924054A0 (fi) 1992-09-10
FI924054L (fi) 1993-03-15
AU2353392A (en) 1993-03-18
NO300326B1 (no) 1997-05-12
PL295911A1 (en) 1993-03-22
RU2076105C1 (ru) 1997-03-27
TW300219B (enExample) 1997-03-11
NO923535L (no) 1993-03-15
IL103141A0 (en) 1993-02-21
NZ244303A (en) 1995-12-21
KR930006020A (ko) 1993-04-20
JP3459659B2 (ja) 2003-10-20
EP0533058A1 (de) 1993-03-24
CN1070646A (zh) 1993-04-07
NO923535D0 (no) 1992-09-11
CA2078058A1 (en) 1993-03-15
PL171766B1 (pl) 1997-06-30
ES2204888T3 (es) 2004-05-01
US5444068A (en) 1995-08-22
JPH05262742A (ja) 1993-10-12
HU9202931D0 (en) 1992-11-30
EP0533058B1 (de) 2003-08-20

Similar Documents

Publication Publication Date Title
FI924054A7 (fi) Imidatsoliin liitetyt iso- ja heterosyklit, menetelmä niiden valmistamiseksi ja niiden käyttö
FI941538A7 (fi) Partikkelit, menetelmä niiden valmistamiseksi ja niiden käyttö
FI924963A7 (fi) Tärkkelyskuidut, menetelmä niiden valmistamiseksi sekä niiden käyttö
FI920017A7 (fi) Atsolijohdoksia, menetelmiä niiden valmistamiseksi ja niiden käyttö
FI952179A7 (fi) Uusia 3,3-difenyylipropyyliamiineja, niiden käyttö ja valmistus
FI955235L (fi) Oksatsolidiinionijohdannaiset, niiden valmistus ja käyttö
FI935465L (fi) Termoplastinen koostumus, menetelmä sen valmistamiseksi ja sen käyttö
FI951468L (fi) Lipopeptidijohdannaiset, menetelmä niiden valmistamiseksi ja niiden käyttö
FI935897A7 (fi) Pyridopyrimidiinijohdannaiset, niiden valmistus ja käyttö
FI931499A7 (fi) Syklopeptidit, menetelmä niiden valmistamiseksi ja niiden käyttö lääke aineina
FI935887L (fi) Tiatzolidiinidionijohdannaiset, niiden valmistus ja käyttö
FI922875A7 (fi) Reniiniä estävät yhdisteet, menetelmä niiden valmistamiseksi ja niidenkäyttö
FI902629A7 (fi) Aryylioksifenyylipropyyliamiineja, niiden valmistus ja käyttö
FI921525A7 (fi) Amidinofenyylialaniinijohdannaisia, menetelmä niiden valmistamiseksi, niiden käyttö ja niitä sisältäviä aineita
FI900461A7 (fi) Imidatsopyridatsiinit, niiden valmistus ja käyttö
FI940775L (fi) alfa-fenyyli-isoseriinijohdannaisten valmistusmentelmä ja niiden käyttö
FI910696A7 (fi) SiO2-himmennysaine, menetelmä sen valmistamiseksi ja sen käyttö
KR900701751A (ko) 치환 알릴아민 유도체, 그의 제조방법 및 그의 용도
FI923755A7 (fi) Disulfideja, menetelmiä niiden valmistamiseksi ja niiden käyttö
FI934680A7 (fi) Aryylimorfoliini, valmistus ja käyttö
FI930716A7 (fi) Uusia aryylikarbonyyliaminoalkyylidihydro-oksopyridiinejä, niiden valmistus ja käyttö
FI900627A7 (fi) 2,3,23-trihydroksiurs-12-eeni ja sen johdannaiset, menetelmiä niiden valmistamiseksi ja niiden käyttö
FI942912A7 (fi) Substituoidut bentsimidatsolit, menetelmä niiden valmistamiseksi sekä niiden käyttö
FI932863A7 (fi) Menetelmä uusien tienotiatsiinijohdosten valmistamiseksi ja niiden käyttö
FI981359L (fi) Uudet tiomarinolin johdannaiset ja menetelmät niiden valmistamiseksi

Legal Events

Date Code Title Description
FD Application lapsed