FI902002A7 - Menetelmä kinatsoliinijohdannaisten valmistamiseksi - Google Patents

Menetelmä kinatsoliinijohdannaisten valmistamiseksi Download PDF

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Publication number
FI902002A7
FI902002A7 FI902002A FI902002A FI902002A7 FI 902002 A7 FI902002 A7 FI 902002A7 FI 902002 A FI902002 A FI 902002A FI 902002 A FI902002 A FI 902002A FI 902002 A7 FI902002 A7 FI 902002A7
Authority
FI
Finland
Prior art keywords
quinazoline derivatives
preparing quinazoline
preparing
derivatives
quinazoline
Prior art date
Application number
FI902002A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI902002A0 (fi
Inventor
Jozsef Reiter
Frigyes Görgenyi
Laszlo Pongo
Marton Fekete
Margit Csörgö
Ilona Sztuhar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU193089A external-priority patent/HU203333B/hu
Priority claimed from HU193189A external-priority patent/HU203342B/hu
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of FI902002A0 publication Critical patent/FI902002A0/fi
Publication of FI902002A7 publication Critical patent/FI902002A7/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI902002A 1989-04-21 1990-04-20 Menetelmä kinatsoliinijohdannaisten valmistamiseksi FI902002A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU193089A HU203333B (en) 1989-04-21 1989-04-21 Process for producing n-cyano-carboxamidine derivatives
HU193189A HU203342B (en) 1989-04-21 1989-04-21 Process for producing quinazoline deivatives

Publications (2)

Publication Number Publication Date
FI902002A0 FI902002A0 (fi) 1990-04-20
FI902002A7 true FI902002A7 (fi) 1990-10-22

Family

ID=26317437

Family Applications (1)

Application Number Title Priority Date Filing Date
FI902002A FI902002A7 (fi) 1989-04-21 1990-04-20 Menetelmä kinatsoliinijohdannaisten valmistamiseksi

Country Status (16)

Country Link
JP (1) JPH02292282A (enrdf_load_stackoverflow)
KR (1) KR900016194A (enrdf_load_stackoverflow)
AT (1) AT398075B (enrdf_load_stackoverflow)
BG (1) BG91821A (enrdf_load_stackoverflow)
CA (2) CA2028953A1 (enrdf_load_stackoverflow)
CH (1) CH681300A5 (enrdf_load_stackoverflow)
DK (1) DK99090A (enrdf_load_stackoverflow)
ES (1) ES2019826A6 (enrdf_load_stackoverflow)
FI (1) FI902002A7 (enrdf_load_stackoverflow)
GB (1) GB2231571B (enrdf_load_stackoverflow)
GR (1) GR900100294A (enrdf_load_stackoverflow)
IT (1) IT1241128B (enrdf_load_stackoverflow)
PL (1) PL162976B1 (enrdf_load_stackoverflow)
RU (1) RU1838309C (enrdf_load_stackoverflow)
SE (1) SE9001402L (enrdf_load_stackoverflow)
YU (1) YU70890A (enrdf_load_stackoverflow)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
ES2096518B1 (es) * 1994-03-28 1997-12-01 Grupo Farmaceutico Almirall S Nuevas anilinas.
WO2008015525A2 (en) * 2006-07-31 2008-02-07 Orchid Chemicals & Pharmaceuticals Limited An improved process for the preparation of alfuzosin hydrochloride
US20100174073A1 (en) 2007-05-04 2010-07-08 Actavis Group Ptc Ehf Process for the preparation of alfuzosin and salts thereof
EP2178864B1 (en) 2007-08-02 2014-07-23 Cipla Limited Process for the preparation of alfuzosin hydrochloride

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4026894A (en) * 1975-10-14 1977-05-31 Abbott Laboratories Antihypertensive agents
US4044135A (en) * 1975-10-14 1977-08-23 Abbott Laboratories Antihypertensive agents
GB1591490A (en) * 1977-08-04 1981-06-24 Abbott Lab 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate
US4138561A (en) * 1977-09-30 1979-02-06 Bristol-Myers Company Cyanocarboxamidines and quinazoline process
FI57751C (fi) * 1977-10-25 1980-10-10 Fermion Oy Foerfarande foer framstaellning av 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner med blodtryckssaenkande verkan
FI56836C (fi) * 1977-10-25 1980-04-10 Fermion Oy 4-substituerade piperazin-1-(n-aryl-n'-cyano)-karboximidamider som aer mellanprodukter vid framstaellningen av farmakologiskt vaerdefulla 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner
FR2421888A1 (fr) * 1978-02-06 1979-11-02 Synthelabo Amides d'alkylene-diamines et leur application en therapeutique
FI59800C (fi) * 1979-01-10 1981-10-12 Fermion Oy Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(furo-2-yl)-piperazin-1-yl)-kinazolin
FI67699C (fi) * 1979-01-31 1985-05-10 Orion Yhtymae Oy Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan
DE3375395D1 (en) * 1983-11-22 1988-02-25 Heumann Ludwig & Co Gmbh Process for the preparation of 4-amino-6,7-dimethoxy-2-(4-(furoyl-2)-piperazin-1-yl)-quinazoline and its physiologically acceptable salt

Also Published As

Publication number Publication date
PL162976B1 (pl) 1994-01-31
ATA93190A (de) 1994-01-15
RU1838309C (ru) 1993-08-30
IT9020092A1 (it) 1991-10-20
DK99090A (da) 1990-10-22
PL284860A1 (en) 1991-03-11
BG91821A (bg) 1993-12-24
GB9008941D0 (en) 1990-06-20
IT1241128B (it) 1993-12-29
CH681300A5 (enrdf_load_stackoverflow) 1993-02-26
SE9001402D0 (sv) 1990-04-20
AT398075B (de) 1994-09-26
CA2028953A1 (en) 1990-10-22
SE9001402L (sv) 1990-10-22
GB2231571B (en) 1992-09-16
KR900016194A (ko) 1990-11-12
ES2019826A6 (es) 1991-07-01
YU70890A (en) 1992-05-28
IT9020092A0 (it) 1990-04-20
DK99090D0 (da) 1990-04-20
CA2015066A1 (en) 1990-10-21
JPH02292282A (ja) 1990-12-03
GR900100294A (el) 1991-09-27
FI902002A0 (fi) 1990-04-20
GB2231571A (en) 1990-11-21

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Legal Events

Date Code Title Description
FD Application lapsed
MM Patent lapsed

Owner name: EGIS GYOGYSZERGYAR