FI893364A - Foerfarande foer framstaellning av 02,2'-anhydro-1-(b-d-arabinofuranosyl)tymin. - Google Patents
Foerfarande foer framstaellning av 02,2'-anhydro-1-(b-d-arabinofuranosyl)tymin. Download PDFInfo
- Publication number
- FI893364A FI893364A FI893364A FI893364A FI893364A FI 893364 A FI893364 A FI 893364A FI 893364 A FI893364 A FI 893364A FI 893364 A FI893364 A FI 893364A FI 893364 A FI893364 A FI 893364A
- Authority
- FI
- Finland
- Prior art keywords
- arabinofuranosyl
- anhydro
- framstaellning
- thyme
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/09—Pyrimidine radicals with arabinosyl as the saccharide radical
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/217,906 US5008384A (en) | 1988-07-12 | 1988-07-12 | Process for the production of O.sup. 2,2'-anhydro-1-(β-D-arabinofuranosyl)thymine |
Publications (2)
Publication Number | Publication Date |
---|---|
FI893364A0 FI893364A0 (fi) | 1989-07-11 |
FI893364A true FI893364A (fi) | 1990-01-13 |
Family
ID=22812966
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI893364A FI893364A (fi) | 1988-07-12 | 1989-07-11 | Foerfarande foer framstaellning av 02,2'-anhydro-1-(b-d-arabinofuranosyl)tymin. |
Country Status (21)
Country | Link |
---|---|
US (1) | US5008384A (pt) |
EP (1) | EP0351126B1 (pt) |
JP (1) | JPH075626B2 (pt) |
KR (1) | KR910008112B1 (pt) |
CN (1) | CN1039423A (pt) |
AT (1) | ATE117314T1 (pt) |
AU (1) | AU603042B2 (pt) |
CA (1) | CA1315776C (pt) |
DD (2) | DD292003A5 (pt) |
DE (1) | DE68920648T2 (pt) |
DK (1) | DK342189A (pt) |
ES (1) | ES2066853T3 (pt) |
FI (1) | FI893364A (pt) |
GR (1) | GR3015293T3 (pt) |
HU (1) | HUT50843A (pt) |
IE (1) | IE65735B1 (pt) |
IL (1) | IL90884A0 (pt) |
NO (1) | NO892821L (pt) |
PT (1) | PT91113B (pt) |
YU (1) | YU138789A (pt) |
ZA (1) | ZA895259B (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3065350B2 (ja) * | 1990-11-30 | 2000-07-17 | ヤマサ醤油株式会社 | 1―(2,3―ジデオキシ―β―D―グリセロ―ペント―2―エノフラノシル)チミンの製造法 |
ES2125408T3 (es) * | 1994-05-20 | 1999-03-01 | Council Scient Ind Res | Un procedimiento para la preparacion de beta-timidina. |
US7125983B2 (en) | 2000-11-29 | 2006-10-24 | Mitsui Chemicals, Inc. | L-nucleic acid derivatives and process for the synthesis thereof |
ES2243726T3 (es) * | 2001-03-30 | 2005-12-01 | Gilead Sciences, Inc. | Procedimiento de preparacion de 2'-halo-beta-l-arabinofuranosil nucleosidos. |
DE10216426A1 (de) * | 2002-04-12 | 2003-10-23 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von beta-L-2'Deoxy-Thymidin |
KR20060015542A (ko) | 2003-04-28 | 2006-02-17 | 이데닉스 (케이만) 리미티드 | 산업 규모의 뉴클레오시드 합성 |
WO2005003374A2 (en) | 2003-06-30 | 2005-01-13 | Idenix (Cayman) Limited | SYNTHESIS OF β-L-2-DEOXY NUCLEOSIDES |
EP2007784A2 (en) | 2006-03-15 | 2008-12-31 | Novartis AG | Process for preparing l-nucleic acid derivatives and intermediates thereof |
JP5504179B2 (ja) | 2008-03-03 | 2014-05-28 | トスク インコーポレーティッド | 毒性を低減するためのメトトレキセートアジュバントおよびその使用法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3322747A (en) * | 1965-04-01 | 1967-05-30 | Merck & Co Inc | Thionocarbonate nucleosides |
US3463850A (en) * | 1967-01-03 | 1969-08-26 | Merck & Co Inc | Arabinofuranosyl 2-thiopyrimidines and pharmaceutical compositions thereof |
US3658788A (en) * | 1969-06-06 | 1972-04-25 | Salk Inst For Biological Studi | Aminooxazolines and products thereof and processes for synthesizing same |
US3812098A (en) * | 1970-03-19 | 1974-05-21 | Syntex Inc | O2,2'-anhydro-1-(beta-d-arabinofuranosyl)-cytosine derivatives and methods of making and related procedures |
US3709874A (en) * | 1970-03-19 | 1973-01-09 | Syntex Corp | 1-beta-d-arabinofuranosyl cytosine derivatives and methods of preparing |
US3792040A (en) * | 1970-03-19 | 1974-02-12 | Syntex Corp | Acyl derivatives of o2,2'-anhydro-1-(beta-d-arabinofuranosyl)-cytosines and methods of preparing |
US3920630A (en) * | 1970-09-24 | 1975-11-18 | Upjohn Co | 2,2{40 -Anhydro-ara-cytidine compounds and process of preparation |
SE391183B (sv) * | 1971-04-15 | 1977-02-07 | Asahi Chemical Ind | 2',3'-0-sulfinylcytidin och syraadditionssalter derav till anvendning som mellanprodukt for framstellning av 2,2'-anhydro-(1-beta-d-arabinofuranosyl) cytosin |
US3978042A (en) * | 1975-01-31 | 1976-08-31 | The Upjohn Company | Process for preparing cyclocytidine derivatives |
US4140850A (en) * | 1977-08-29 | 1979-02-20 | The Upjohn Company | 2,2'-Anhydrotriazine nucleosides and process for preparing the same |
JPS5649398A (en) * | 1979-09-28 | 1981-05-02 | Yamasa Shoyu Co Ltd | Preparation of 1-beta-d-arabinofuranosyl-2,2'-cyclothymine |
JPS636557A (ja) * | 1986-06-26 | 1988-01-12 | Sharp Corp | 微細パタ−ン形成方法 |
-
1988
- 1988-07-12 US US07/217,906 patent/US5008384A/en not_active Expired - Lifetime
-
1989
- 1989-07-05 ES ES89306820T patent/ES2066853T3/es not_active Expired - Lifetime
- 1989-07-05 AT AT89306820T patent/ATE117314T1/de not_active IP Right Cessation
- 1989-07-05 EP EP89306820A patent/EP0351126B1/en not_active Expired - Lifetime
- 1989-07-05 IL IL90884A patent/IL90884A0/xx unknown
- 1989-07-05 DE DE68920648T patent/DE68920648T2/de not_active Expired - Fee Related
- 1989-07-07 NO NO89892821A patent/NO892821L/no unknown
- 1989-07-10 CN CN89104789A patent/CN1039423A/zh active Pending
- 1989-07-10 PT PT91113A patent/PT91113B/pt not_active IP Right Cessation
- 1989-07-10 JP JP1177876A patent/JPH075626B2/ja not_active Expired - Fee Related
- 1989-07-10 CA CA000605243A patent/CA1315776C/en not_active Expired - Fee Related
- 1989-07-11 DD DD89337873A patent/DD292003A5/de not_active IP Right Cessation
- 1989-07-11 YU YU01387/89A patent/YU138789A/xx unknown
- 1989-07-11 ZA ZA895259A patent/ZA895259B/xx unknown
- 1989-07-11 AU AU38020/89A patent/AU603042B2/en not_active Ceased
- 1989-07-11 HU HU893491A patent/HUT50843A/hu unknown
- 1989-07-11 KR KR1019890009853A patent/KR910008112B1/ko active IP Right Grant
- 1989-07-11 DK DK342189A patent/DK342189A/da not_active Application Discontinuation
- 1989-07-11 DD DD89330684A patent/DD284024A5/de not_active IP Right Cessation
- 1989-07-11 IE IE223389A patent/IE65735B1/en not_active IP Right Cessation
- 1989-07-11 FI FI893364A patent/FI893364A/fi not_active Application Discontinuation
-
1995
- 1995-03-03 GR GR950400471T patent/GR3015293T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH075626B2 (ja) | 1995-01-25 |
DK342189D0 (da) | 1989-07-11 |
EP0351126A2 (en) | 1990-01-17 |
ES2066853T3 (es) | 1995-03-16 |
EP0351126A3 (en) | 1990-10-24 |
NO892821L (no) | 1990-01-15 |
KR910008112B1 (ko) | 1991-10-10 |
ATE117314T1 (de) | 1995-02-15 |
IE892233L (en) | 1990-01-12 |
PT91113B (pt) | 1995-01-31 |
DD284024A5 (de) | 1990-10-31 |
IL90884A0 (en) | 1990-02-09 |
AU603042B2 (en) | 1990-11-01 |
US5008384A (en) | 1991-04-16 |
ZA895259B (en) | 1991-02-27 |
GR3015293T3 (en) | 1995-06-30 |
IE65735B1 (en) | 1995-11-15 |
EP0351126B1 (en) | 1995-01-18 |
DE68920648D1 (de) | 1995-03-02 |
NO892821D0 (no) | 1989-07-07 |
JPH0259598A (ja) | 1990-02-28 |
KR900001704A (ko) | 1990-02-27 |
PT91113A (pt) | 1990-02-08 |
DK342189A (da) | 1990-01-15 |
FI893364A0 (fi) | 1989-07-11 |
DE68920648T2 (de) | 1995-05-18 |
YU138789A (en) | 1990-12-31 |
CN1039423A (zh) | 1990-02-07 |
HUT50843A (en) | 1990-03-28 |
AU3802089A (en) | 1990-04-26 |
DD292003A5 (de) | 1991-07-18 |
CA1315776C (en) | 1993-04-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |
Owner name: PFIZER INC. |