FI88403C - Monoklonala antikroppar, foerfarande foer framstaellning av dessa och affinitetsreningsfoerfarande vari dessa anvaends - Google Patents

Monoklonala antikroppar, foerfarande foer framstaellning av dessa och affinitetsreningsfoerfarande vari dessa anvaends Download PDF

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Publication number
FI88403C
FI88403C FI834530A FI834530A FI88403C FI 88403 C FI88403 C FI 88403C FI 834530 A FI834530 A FI 834530A FI 834530 A FI834530 A FI 834530A FI 88403 C FI88403 C FI 88403C
Authority
FI
Finland
Prior art keywords
antigen
environment
antibody
medium
antibodies
Prior art date
Application number
FI834530A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI834530A (fi
FI88403B (fi
FI834530A0 (fi
Inventor
Richard M Bartholomew
Daniel E Beidler
Gary S David
Original Assignee
Hybritech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybritech Inc filed Critical Hybritech Inc
Publication of FI834530A publication Critical patent/FI834530A/fi
Publication of FI834530A0 publication Critical patent/FI834530A0/fi
Application granted granted Critical
Publication of FI88403B publication Critical patent/FI88403B/fi
Publication of FI88403C publication Critical patent/FI88403C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI834530A 1982-04-12 1983-12-09 Monoklonala antikroppar, foerfarande foer framstaellning av dessa och affinitetsreningsfoerfarande vari dessa anvaends FI88403C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US36778182A 1982-04-12 1982-04-12
US36778182 1982-04-12
PCT/US1983/000524 WO1983003678A1 (en) 1982-04-12 1983-04-12 Method of affinity purification employing monoclonal antibodies
US8300524 1983-04-12

Publications (4)

Publication Number Publication Date
FI834530A FI834530A (fi) 1983-12-09
FI834530A0 FI834530A0 (fi) 1983-12-09
FI88403B FI88403B (fi) 1993-01-29
FI88403C true FI88403C (fi) 1993-05-10

Family

ID=23448565

Family Applications (1)

Application Number Title Priority Date Filing Date
FI834530A FI88403C (fi) 1982-04-12 1983-12-09 Monoklonala antikroppar, foerfarande foer framstaellning av dessa och affinitetsreningsfoerfarande vari dessa anvaends

Country Status (11)

Country Link
EP (1) EP0105359A4 (es)
AT (1) AT393386B (es)
AU (1) AU622099B2 (es)
CA (1) CA1209907A (es)
CH (1) CH672028A5 (es)
DK (1) DK192191D0 (es)
ES (3) ES8404858A1 (es)
FI (1) FI88403C (es)
GB (1) GB2128630B (es)
IT (1) IT1219779B (es)
WO (1) WO1983003678A1 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8328918D0 (en) * 1983-10-28 1983-11-30 Unilever Plc Alkaline phosphatase
GB8331071D0 (en) * 1983-11-22 1983-12-29 Karayiannis P Assay for dna/rna
US4666865A (en) * 1984-01-13 1987-05-19 Centocor, Inc. Immunoassay for biologically active human interferon-gamma employing unique monoclonal antibodies
US4789631A (en) * 1984-02-17 1988-12-06 Synbiotics Corporation Immunoassay for anti-dirofilaria immitis antibody
GB8426468D0 (en) * 1984-10-19 1984-11-28 Technology Licence Co Ltd Monoclonal antibodies
AU5259786A (en) * 1985-01-30 1986-08-07 United States Of America, The Monoclonal antibodies against chlamydial genes specific lipopolysaccharide
US4818687A (en) * 1985-02-28 1989-04-04 Massachusetts Institute Of Technology Affinity column and process for detection of low molecular weight toxic substances
US4859611A (en) * 1985-02-28 1989-08-22 Massachusetts Institute Of Technology Affinity column and process for detection of low molecular weight toxic substances
IL75828A (en) * 1985-07-17 1991-06-10 Univ Ramot Immobilization by biologically active proteins
NZ218336A (en) * 1985-12-09 1991-08-27 Kirin Amgen Inc Monoclonal antibodies to human pluripotent granulocyte colony stimulating factor (hpg-csf)
US5175255A (en) * 1987-03-23 1992-12-29 Amgen Inc. Methods for purification of platelet-derived growth factor
US5190859A (en) * 1987-02-26 1993-03-02 Dana-Farber Cancer Institute, Inc. Purification of LFA-3
SE468653B (sv) * 1987-03-06 1993-02-22 Perstorp Biolytica Adsorbent foer isokratisk affinitetskromatografi
JPS6463599A (en) * 1987-05-01 1989-03-09 Xoma Corp Purification of immunoglobulin by selective anti-idiotype bond
WO1989000695A1 (en) * 1987-07-14 1989-01-26 The Victoria University Of Manchester Method for the diagnosis of infections with detection of lipopolysaccharide antigens
CA1323567C (en) * 1987-10-05 1993-10-26 Gene R. Nathans Method for purification of antibodies
US5582862A (en) * 1988-04-04 1996-12-10 General Hospital Corporation Antibodies that bind to α2-antiplasmin crosslinked to fibrin which do not inhibit plasma α2-antiplasmin
US5372812A (en) * 1988-04-04 1994-12-13 The General Hospital Corporation Composition and method for acceleration of clot lysis
EP0937146A2 (en) * 1996-09-20 1999-08-25 The General Hospital Corporation Composition and method for enhancing fibrinolysis using antibodies to alpha-2-antiplasmin
EP3521311A1 (en) * 2008-04-11 2019-08-07 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
RU2642318C2 (ru) 2010-11-30 2018-01-24 Чугаи Сейяку Кабусики Кайся Антигенсвязывающая молекула, способная многократно связываться с множеством антигенных молекул
CN112812184A (zh) 2011-02-25 2021-05-18 中外制药株式会社 FcγRIIb特异性Fc抗体
WO2013047748A1 (ja) 2011-09-30 2013-04-04 中外製薬株式会社 複数の生理活性を有する抗原の消失を促進する抗原結合分子
EP3517550A1 (en) 2011-11-30 2019-07-31 Chugai Seiyaku Kabushiki Kaisha Drug containing carrier into cell for forming immune complex
SG11201700841QA (en) 2014-12-19 2017-03-30 Chugai Pharmaceutical Co Ltd Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use
LT3233921T (lt) 2014-12-19 2021-12-10 Chugai Seiyaku Kabushiki Kaisha Anti-c5 antikūnai ir panaudojimo būdai
US11359009B2 (en) 2015-12-25 2022-06-14 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
TWI693940B (zh) 2016-08-05 2020-05-21 日商中外製藥股份有限公司 Ｉｌ-８相關疾病之治療用或預防用組成物
US11608374B2 (en) 2017-01-30 2023-03-21 Chugai Seiyaku Kabushiki Kaisha Anti-sclerostin antibodies and methods of use
CN110724204B (zh) * 2019-11-18 2021-10-22 广东菲鹏制药股份有限公司 Fc融合蛋白的纯化方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172124A (en) * 1978-04-28 1979-10-23 The Wistar Institute Method of producing tumor antibodies
EP0059598B1 (en) * 1981-02-26 1985-07-17 Unilever Plc A process and apparatus for the recovery of immunoglobulines
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies

Also Published As

Publication number Publication date
ES8706964A1 (es) 1987-07-01
EP0105359A1 (en) 1984-04-18
IT1219779B (it) 1990-05-24
DK192191A (da) 1991-11-26
CH672028A5 (es) 1989-10-13
WO1983003678A1 (en) 1983-10-27
DK192191D0 (da) 1991-11-26
EP0105359A4 (en) 1984-08-20
ES528000A0 (es) 1985-08-01
AU7256987A (en) 1987-09-03
ATA901983A (de) 1991-03-15
ES521371A0 (es) 1984-05-16
CA1209907A (en) 1986-08-19
AU622099B2 (en) 1992-04-02
IT8320550A0 (it) 1983-04-12
GB8332644D0 (en) 1984-01-11
GB2128630B (en) 1986-08-28
FI834530A (fi) 1983-12-09
FI88403B (fi) 1993-01-29
GB2128630A (en) 1984-05-02
FI834530A0 (fi) 1983-12-09
ES8404858A1 (es) 1984-05-16
ES8506902A1 (es) 1985-08-01
ES528001A0 (es) 1987-07-01
AT393386B (de) 1991-10-10

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Owner name: HYBRITECH INCORPORATED