DK192191A - Monoclonalt antistof og dets fremstilling og anvendelse i affinitets-rensningsprocesser - Google Patents

Monoclonalt antistof og dets fremstilling og anvendelse i affinitets-rensningsprocesser Download PDF

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Publication number
DK192191A
DK192191A DK192191A DK192191A DK192191A DK 192191 A DK192191 A DK 192191A DK 192191 A DK192191 A DK 192191A DK 192191 A DK192191 A DK 192191A DK 192191 A DK192191 A DK 192191A
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DK
Denmark
Prior art keywords
manufacturing
monoclonal antibody
cleaning processes
affinity
affinity cleaning
Prior art date
Application number
DK192191A
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English (en)
Other versions
DK192191D0 (da
Inventor
Richard M Bartholomew
Daniel E Beidler
Gary S David
Original Assignee
Hybritech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybritech Inc filed Critical Hybritech Inc
Publication of DK192191A publication Critical patent/DK192191A/da
Publication of DK192191D0 publication Critical patent/DK192191D0/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Description

Figure DK192191AD00021
DK911921A 1982-04-12 1991-11-26 Monoclonalt antistof og dets fremstilling og anvendelse i affinitets-rensningsprocesser DK192191D0 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36778182A 1982-04-12 1982-04-12
PCT/US1983/000524 WO1983003678A1 (en) 1982-04-12 1983-04-12 Method of affinity purification employing monoclonal antibodies

Publications (2)

Publication Number Publication Date
DK192191A true DK192191A (da) 1991-11-26
DK192191D0 DK192191D0 (da) 1991-11-26

Family

ID=23448565

Family Applications (1)

Application Number Title Priority Date Filing Date
DK911921A DK192191D0 (da) 1982-04-12 1991-11-26 Monoclonalt antistof og dets fremstilling og anvendelse i affinitets-rensningsprocesser

Country Status (11)

Country Link
EP (1) EP0105359A4 (da)
AT (1) AT393386B (da)
AU (1) AU622099B2 (da)
CA (1) CA1209907A (da)
CH (1) CH672028A5 (da)
DK (1) DK192191D0 (da)
ES (3) ES521371A0 (da)
FI (1) FI88403C (da)
GB (1) GB2128630B (da)
IT (1) IT1219779B (da)
WO (1) WO1983003678A1 (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8328918D0 (en) * 1983-10-28 1983-11-30 Unilever Plc Alkaline phosphatase
GB8331071D0 (en) * 1983-11-22 1983-12-29 Karayiannis P Assay for dna/rna
US4666865A (en) * 1984-01-13 1987-05-19 Centocor, Inc. Immunoassay for biologically active human interferon-gamma employing unique monoclonal antibodies
US4789631A (en) * 1984-02-17 1988-12-06 Synbiotics Corporation Immunoassay for anti-dirofilaria immitis antibody
GB8426468D0 (en) * 1984-10-19 1984-11-28 Technology Licence Co Ltd Monoclonal antibodies
AU5259786A (en) * 1985-01-30 1986-08-07 United States Of America, The Monoclonal antibodies against chlamydial genes specific lipopolysaccharide
US4818687A (en) * 1985-02-28 1989-04-04 Massachusetts Institute Of Technology Affinity column and process for detection of low molecular weight toxic substances
US4859611A (en) * 1985-02-28 1989-08-22 Massachusetts Institute Of Technology Affinity column and process for detection of low molecular weight toxic substances
IL75828A (en) * 1985-07-17 1991-06-10 Univ Ramot Immobilization by biologically active proteins
NZ218336A (en) * 1985-12-09 1991-08-27 Kirin Amgen Inc Monoclonal antibodies to human pluripotent granulocyte colony stimulating factor (hpg-csf)
US5175255A (en) * 1987-03-23 1992-12-29 Amgen Inc. Methods for purification of platelet-derived growth factor
US5190859A (en) * 1987-02-26 1993-03-02 Dana-Farber Cancer Institute, Inc. Purification of LFA-3
SE468653B (sv) * 1987-03-06 1993-02-22 Perstorp Biolytica Adsorbent foer isokratisk affinitetskromatografi
JPS6463599A (en) * 1987-05-01 1989-03-09 Xoma Corp Purification of immunoglobulin by selective anti-idiotype bond
DE3871799D1 (de) * 1987-07-14 1992-07-09 Univ Manchester Verfahren zur diagnose von infektionen, bei welchem lipopolyscaccharidantigene bestimmt werden.
CA1323567C (en) * 1987-10-05 1993-10-26 Gene R. Nathans Method for purification of antibodies
US5372812A (en) * 1988-04-04 1994-12-13 The General Hospital Corporation Composition and method for acceleration of clot lysis
US5582862A (en) * 1988-04-04 1996-12-10 General Hospital Corporation Antibodies that bind to α2-antiplasmin crosslinked to fibrin which do not inhibit plasma α2-antiplasmin
US20030017147A1 (en) * 1996-09-20 2003-01-23 Guy L Reed Composition and method for enhancing fibrinolysis
TWI700293B (zh) * 2008-04-11 2020-08-01 日商中外製藥股份有限公司 重複結合複數個抗原的抗體
KR102568454B1 (ko) 2010-11-30 2023-08-18 추가이 세이야쿠 가부시키가이샤 복수 분자의 항원에 반복해서 결합하는 항원 결합 분자
EP3604330A1 (en) 2011-02-25 2020-02-05 Chugai Seiyaku Kabushiki Kaisha Fcgammariib-specific fc antibody
JP6322411B2 (ja) 2011-09-30 2018-05-09 中外製薬株式会社 複数の生理活性を有する抗原の消失を促進する抗原結合分子
BR112014013081A2 (pt) 2011-11-30 2020-10-20 Chugai Seiyaku Kabushiki Kaisha veículo contendo fármaco em célula para formação de um complexo imune
KR101838645B1 (ko) 2014-12-19 2018-03-14 추가이 세이야쿠 가부시키가이샤 항-c5 항체 및 그의 사용 방법
TWI656133B (zh) 2014-12-19 2019-04-11 日商中外製藥股份有限公司 抗肌抑素之抗體、含變異Ｆｃ區域之多胜肽及使用方法
WO2017110981A1 (en) 2015-12-25 2017-06-29 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
CN109689099B (zh) 2016-08-05 2023-02-28 中外制药株式会社 用于预防或治疗il-8相关疾病的组合物
WO2018139623A1 (en) 2017-01-30 2018-08-02 Chugai Seiyaku Kabushiki Kaisha Anti-sclerostin antibodies and methods of use
CN110724204B (zh) * 2019-11-18 2021-10-22 广东菲鹏制药股份有限公司 Fc融合蛋白的纯化方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172124A (en) * 1978-04-28 1979-10-23 The Wistar Institute Method of producing tumor antibodies
WO1982002818A1 (en) * 1981-02-26 1982-09-02 Gani Mohamed Mutwahar A process and apparatus for the recovery of immunoglobulins
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies

Also Published As

Publication number Publication date
WO1983003678A1 (en) 1983-10-27
ATA901983A (de) 1991-03-15
AU622099B2 (en) 1992-04-02
GB2128630B (en) 1986-08-28
IT1219779B (it) 1990-05-24
CA1209907A (en) 1986-08-19
EP0105359A1 (en) 1984-04-18
ES8506902A1 (es) 1985-08-01
GB8332644D0 (en) 1984-01-11
ES528000A0 (es) 1985-08-01
CH672028A5 (da) 1989-10-13
FI834530L (fi) 1983-12-09
ES528001A0 (es) 1987-07-01
AT393386B (de) 1991-10-10
AU7256987A (en) 1987-09-03
ES8404858A1 (es) 1984-05-16
FI834530A0 (fi) 1983-12-09
ES521371A0 (es) 1984-05-16
FI88403C (fi) 1993-05-10
FI88403B (fi) 1993-01-29
IT8320550A0 (it) 1983-04-12
DK192191D0 (da) 1991-11-26
ES8706964A1 (es) 1987-07-01
GB2128630A (en) 1984-05-02
EP0105359A4 (en) 1984-08-20

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