DE3587714D1 - Menschliches alpha 2-Plasmin spezifischer monoklonaler Antikörper. - Google Patents

Menschliches alpha 2-Plasmin spezifischer monoklonaler Antikörper.

Info

Publication number
DE3587714D1
DE3587714D1 DE85104629T DE3587714T DE3587714D1 DE 3587714 D1 DE3587714 D1 DE 3587714D1 DE 85104629 T DE85104629 T DE 85104629T DE 3587714 T DE3587714 T DE 3587714T DE 3587714 D1 DE3587714 D1 DE 3587714D1
Authority
DE
Germany
Prior art keywords
monoclonal antibody
specific monoclonal
human alpha
plasmin specific
plasmin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE85104629T
Other languages
English (en)
Other versions
DE3587714T2 (de
Inventor
Yoshihiko Sumi
Yukiya Koike
Yataro Ichikawa
Nobuhiko Jichiidai-Sho Yoshida
Nobuo Aoki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP59075778A external-priority patent/JPS60222426A/ja
Priority claimed from JP8610184A external-priority patent/JPS60231168A/ja
Priority claimed from JP59212587A external-priority patent/JPS6191200A/ja
Priority claimed from JP59217312A external-priority patent/JPS6197230A/ja
Application filed by Teijin Ltd filed Critical Teijin Ltd
Application granted granted Critical
Publication of DE3587714D1 publication Critical patent/DE3587714D1/de
Publication of DE3587714T2 publication Critical patent/DE3587714T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/38—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/863—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving IgM
    • Y10S530/864—Monoclonal
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/866—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving immunoglobulin or antibody fragment, e.g. fab', fab, fv, fc, heavy chain or light chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DE3587714T 1984-04-17 1985-04-17 Menschliches alpha 2-Plasmin spezifischer monoklonaler Antikörper. Expired - Fee Related DE3587714T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP59075778A JPS60222426A (ja) 1984-04-17 1984-04-17 モノクローナル抗体及びモノクローナル抗体の製造方法
JP8610184A JPS60231168A (ja) 1984-05-01 1984-05-01 ヒトα２―プラスミンインヒビターに対するモノクローナル抗体を用いた免疫学的測定試薬及びキット
JP59212587A JPS6191200A (ja) 1984-10-12 1984-10-12 モノクロ−ナル抗体
JP59217312A JPS6197230A (ja) 1984-10-18 1984-10-18 ヒトα↓２―プラスミンインヒビターに対する選択的吸着体

Publications (2)

Publication Number Publication Date
DE3587714D1 true DE3587714D1 (de) 1994-02-17
DE3587714T2 DE3587714T2 (de) 1994-05-19

Family

ID=27465859

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3587714T Expired - Fee Related DE3587714T2 (de) 1984-04-17 1985-04-17 Menschliches alpha 2-Plasmin spezifischer monoklonaler Antikörper.

Country Status (5)

Country Link
US (1) US5534255A (de)
EP (1) EP0159025B1 (de)
DE (1) DE3587714T2 (de)
DK (1) DK166627B1 (de)
NO (1) NO171169C (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62298536A (ja) * 1986-06-17 1987-12-25 Green Cross Corp:The 生理活性物質の自動精製方法および自動精製装置
FI873674A (fi) * 1986-08-27 1988-02-28 Hoechst Japan --2-plasmin-inhibitorliknande protein kodande dna.
US5582862A (en) * 1988-04-04 1996-12-10 General Hospital Corporation Antibodies that bind to α2-antiplasmin crosslinked to fibrin which do not inhibit plasma α2-antiplasmin
US5372812A (en) * 1988-04-04 1994-12-13 The General Hospital Corporation Composition and method for acceleration of clot lysis
JP3291525B2 (ja) * 1990-12-20 2002-06-10 株式会社ヤトロン ヒトプラスミン−α▲下２▼−プラスミンインヒビター複合体の免疫学的測定方法
DE4115993A1 (de) * 1991-05-16 1992-11-19 Behringwerke Ag Monoklonale antikoerper gegen den plasmin-atiplasmin komplex, verfahren zu ihrer herstellung sowie ihre verwendung
JP2001515345A (ja) * 1996-09-20 2001-09-18 ザ・ジェネラル・ホスピタル・コーポレイション アルファ―２―抗プラスミンに対する抗体を用いてフィブリン溶解を増進するための組成物と方法
ES2237272B1 (es) * 2003-03-21 2006-07-16 Universidad De Malaga Reactivo de latex para la deteccion de anticuerpos frente a legionella pneumophila.
WO2012126531A1 (en) * 2011-03-24 2012-09-27 Cavadis B.V. Method for diagnosing acute coronary syndrome (acs)
US11078297B2 (en) * 2014-12-22 2021-08-03 Translational Sciences, Inc. Prophylaxis of thrombosis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR896543A (fr) * 1943-07-29 1945-02-23 Ind D Soule Sa Des Ets Nouvelle pince mobile à verrouillage
NL7602846A (nl) * 1976-03-18 1977-09-20 Leuven Res & Dev Vzw Antiplasmine en een antiserum daartegen.
JPS58148963A (ja) * 1982-03-02 1983-09-05 Maruko Seiyaku Kk サンドウイツチ法によるヒト体液中のアルフア−−１−アンチトリプシン・トリプシン結合物測定用試薬
US4514505A (en) * 1982-05-21 1985-04-30 The Trustees Of Columbia University In The City Of New York Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays
US4474892A (en) * 1983-02-16 1984-10-02 Board Of Trustees Of The Leland Stanford Junior University Two-site immunoassays using monoclonal antibodies of different classes or subclasses and test kits for performing same
BE896543A (fr) * 1983-04-22 1983-08-16 Wallone Region Ensembles d'anticorps monoclonaux deriges contre les proteines humaines impliquees dans la coagulation et la fibrinolyse du sang

Also Published As

Publication number Publication date
NO171169C (no) 1993-02-03
DK170485A (da) 1985-10-18
DK170485D0 (da) 1985-04-16
DK166627B1 (da) 1993-06-21
DE3587714T2 (de) 1994-05-19
EP0159025A2 (de) 1985-10-23
NO851518L (no) 1985-10-18
US5534255A (en) 1996-07-09
EP0159025B1 (de) 1994-01-05
EP0159025A3 (en) 1987-10-28
NO171169B (no) 1992-10-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee