FI86987B - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara fenylkinolinkarboxylsyraderivat. - Google Patents
Foerfarande foer framstaellning av nya terapeutiskt anvaendbara fenylkinolinkarboxylsyraderivat.Info
- Publication number
- FI86987B FI86987B FI842928A FI842928A FI86987B FI 86987 B FI86987 B FI 86987B FI 842928 A FI842928 A FI 842928A FI 842928 A FI842928 A FI 842928A FI 86987 B FI86987 B FI 86987B
- Authority
- FI
- Finland
- Prior art keywords
- fenylkinolinkarboxylsyraderivat
- foerfarande foer
- foer framstaellning
- terapeutiskt anvaendbara
- nya terapeutiskt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
- C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51631983A | 1983-07-22 | 1983-07-22 | |
US51631983 | 1983-07-22 | ||
US60510484A | 1984-04-30 | 1984-04-30 | |
US60510484 | 1984-04-30 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI842928A0 FI842928A0 (fi) | 1984-07-20 |
FI842928A FI842928A (fi) | 1985-01-23 |
FI86987B true FI86987B (fi) | 1992-07-31 |
FI86987C FI86987C (fi) | 1992-11-10 |
Family
ID=27058797
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI842928A FI86987C (fi) | 1983-07-22 | 1984-07-20 | Foerfarande foer framstaellning av nya terapeutiska anvaendbara fenylkinolinkarboxylsyraderivat |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0133244B1 (fi) |
AU (1) | AU583793B2 (fi) |
CA (1) | CA1288436C (fi) |
DE (1) | DE3483704D1 (fi) |
DK (1) | DK358784A (fi) |
ES (1) | ES534509A0 (fi) |
FI (1) | FI86987C (fi) |
GR (1) | GR82234B (fi) |
HK (1) | HK142395A (fi) |
HU (1) | HU194832B (fi) |
IE (1) | IE57627B1 (fi) |
IL (1) | IL72471A (fi) |
NO (1) | NO167510C (fi) |
NZ (1) | NZ208966A (fi) |
PT (1) | PT78960B (fi) |
SU (2) | SU1393314A3 (fi) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4889862A (en) * | 1986-08-28 | 1989-12-26 | E. I. Du Pont De Nemours And Company | Freeze-dried pharmaceutical compositions of phenylquinoline carboxylic acids |
WO1989006227A1 (en) * | 1987-12-28 | 1989-07-13 | The Dow Chemical Company | Phenoxyphenoxypropionates, intermediates thereof and methods of preparation |
US4861783A (en) * | 1988-04-26 | 1989-08-29 | E. I. Du Pont De Nemours And Company | 4-quinoline carboxylic acid derivatives useful for treating skin and muco-epithelial diseases |
US4968702A (en) * | 1989-01-17 | 1990-11-06 | American Cyanamid Company | Substituted quinolinecarboxylic acids |
US4918077A (en) * | 1989-01-25 | 1990-04-17 | E. I. Du Pont De Nemours & Co., Inc. | 3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents |
DE3905339A1 (de) * | 1989-02-22 | 1990-09-06 | Basf Ag | Chinolin-4-carbonsaeurederivate und deren verwendung |
US5393891A (en) * | 1993-06-08 | 1995-02-28 | The Du Pont Merck Pharmaceutical Company | Immunoassay reagents and methods for detecting brequinar and analogs |
PL194980B1 (pl) * | 1997-05-28 | 2007-07-31 | Aventis Pharma Inc | Nowe związki chinolinowe i chinoksalinowe, kompozycja farmaceutyczna je zawierająca oraz ich zastosowanie |
DK0924209T3 (da) * | 1997-12-19 | 2003-08-25 | Lilly Co Eli | Hypoglykæmiske imidazolinforbindelser |
AU2003244080A1 (en) * | 2002-06-26 | 2004-01-19 | Kyowa Hakko Kogyo Co., Ltd. | Phosphodiesterase inhibitor |
US8232310B2 (en) * | 2006-12-29 | 2012-07-31 | Georgetown University | Targeting of EWS-FLI1 as anti-tumor therapy |
CN104395288B (zh) | 2012-04-12 | 2016-12-14 | 乔治城大学 | 用于治疗尤文肉瘤家族肿瘤的方法和组合物 |
RU2016114498A (ru) | 2013-10-24 | 2017-11-29 | Джорджтаун Юниверсити | Способы и композиции для лечения раковых заболеваний |
TN2016000197A1 (en) | 2013-11-22 | 2017-10-06 | Genzyme Corp | Novel methods for treating neurodegenerative diseases. |
EA032644B1 (ru) | 2014-10-09 | 2019-06-28 | Онктернал Терапьютикс, Инк. | Производные индолинона и их применение |
DK3436434T3 (da) | 2016-03-31 | 2020-09-21 | Oncternal Therapeutics Inc | Indolin-analoger og anvendelser deraf |
JP6885629B2 (ja) | 2016-07-29 | 2021-06-16 | オンターナル セラピューティック インコーポレイテッドOncternal Therapeutics, Inc. | インドリノン化合物の使用 |
CA3165512A1 (en) * | 2019-12-26 | 2021-07-01 | Ohio State Innovation Foundation | Methods and compositions for inhibition of dihydroorotate dehydrogenase |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE502610A (fi) * | 1950-04-18 | |||
US2888346A (en) * | 1955-08-22 | 1959-05-26 | Gen Aniline & Film Corp | Ultra-violet absorbing compounds |
-
1984
- 1984-07-19 CA CA000459263A patent/CA1288436C/en not_active Expired - Lifetime
- 1984-07-19 EP EP84108523A patent/EP0133244B1/en not_active Expired - Lifetime
- 1984-07-19 DE DE8484108523T patent/DE3483704D1/de not_active Expired - Lifetime
- 1984-07-19 AU AU30852/84A patent/AU583793B2/en not_active Ceased
- 1984-07-20 FI FI842928A patent/FI86987C/fi not_active IP Right Cessation
- 1984-07-20 SU SU843776940A patent/SU1393314A3/ru active
- 1984-07-20 HU HU842824A patent/HU194832B/hu not_active IP Right Cessation
- 1984-07-20 PT PT78960A patent/PT78960B/pt not_active IP Right Cessation
- 1984-07-20 DK DK358784A patent/DK358784A/da not_active Application Discontinuation
- 1984-07-20 IE IE1873/84A patent/IE57627B1/en not_active IP Right Cessation
- 1984-07-20 IL IL72471A patent/IL72471A/xx not_active IP Right Cessation
- 1984-07-20 NZ NZ208966A patent/NZ208966A/en unknown
- 1984-07-20 ES ES534509A patent/ES534509A0/es active Granted
- 1984-07-20 GR GR75386A patent/GR82234B/el unknown
- 1984-07-20 NO NO842969A patent/NO167510C/no unknown
-
1986
- 1986-01-06 SU SU864000869A patent/SU1452480A3/ru active
-
1995
- 1995-09-07 HK HK142395A patent/HK142395A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ES8507498A1 (es) | 1985-09-01 |
EP0133244B1 (en) | 1990-12-05 |
EP0133244A2 (en) | 1985-02-20 |
ES534509A0 (es) | 1985-09-01 |
PT78960A (en) | 1984-08-01 |
IE57627B1 (en) | 1993-02-10 |
HUT35248A (en) | 1985-06-28 |
NZ208966A (en) | 1986-12-05 |
IL72471A0 (en) | 1984-11-30 |
NO167510B (no) | 1991-08-05 |
IE841873L (en) | 1985-01-22 |
SU1452480A3 (ru) | 1989-01-15 |
DE3483704D1 (de) | 1991-01-17 |
HU194832B (en) | 1988-03-28 |
AU583793B2 (en) | 1989-05-11 |
NO167510C (no) | 1991-11-13 |
FI842928A (fi) | 1985-01-23 |
FI842928A0 (fi) | 1984-07-20 |
DK358784D0 (da) | 1984-07-20 |
IL72471A (en) | 1988-11-15 |
EP0133244A3 (en) | 1985-12-11 |
AU3085284A (en) | 1985-01-24 |
CA1288436C (en) | 1991-09-03 |
GR82234B (fi) | 1984-12-13 |
SU1393314A3 (ru) | 1988-04-30 |
NO842969L (no) | 1985-01-23 |
PT78960B (en) | 1986-10-20 |
HK142395A (en) | 1995-09-15 |
DK358784A (da) | 1985-01-23 |
FI86987C (fi) | 1992-11-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM | Patent lapsed |
Owner name: THE DU PONT MERCK PHARMACEUTICAL COMPANY |