FI842928A - Fenylkinolinkarboxylsyror och deras derivat som tumoerfoerhindrande aemnen. - Google Patents

Fenylkinolinkarboxylsyror och deras derivat som tumoerfoerhindrande aemnen. Download PDF

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Publication number
FI842928A
FI842928A FI842928A FI842928A FI842928A FI 842928 A FI842928 A FI 842928A FI 842928 A FI842928 A FI 842928A FI 842928 A FI842928 A FI 842928A FI 842928 A FI842928 A FI 842928A
Authority
FI
Finland
Prior art keywords
tumoerfoerhindrande
phenylkinolinkarboxylsyror
aemnen
som
och deras
Prior art date
Application number
FI842928A
Other languages
English (en)
Other versions
FI86987C (fi
FI86987B (fi
FI842928A0 (fi
Inventor
David Paul Hesson
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of FI842928A0 publication Critical patent/FI842928A0/fi
Publication of FI842928A publication Critical patent/FI842928A/fi
Application granted granted Critical
Publication of FI86987B publication Critical patent/FI86987B/fi
Publication of FI86987C publication Critical patent/FI86987C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/50Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
    • C07D215/52Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI842928A 1983-07-22 1984-07-20 Foerfarande foer framstaellning av nya terapeutiska anvaendbara fenylkinolinkarboxylsyraderivat FI86987C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US51631983A 1983-07-22 1983-07-22
US51631983 1983-07-22
US60510484A 1984-04-30 1984-04-30
US60510484 1984-04-30

Publications (4)

Publication Number Publication Date
FI842928A0 FI842928A0 (fi) 1984-07-20
FI842928A true FI842928A (fi) 1985-01-23
FI86987B FI86987B (fi) 1992-07-31
FI86987C FI86987C (fi) 1992-11-10

Family

ID=27058797

Family Applications (1)

Application Number Title Priority Date Filing Date
FI842928A FI86987C (fi) 1983-07-22 1984-07-20 Foerfarande foer framstaellning av nya terapeutiska anvaendbara fenylkinolinkarboxylsyraderivat

Country Status (16)

Country Link
EP (1) EP0133244B1 (fi)
AU (1) AU583793B2 (fi)
CA (1) CA1288436C (fi)
DE (1) DE3483704D1 (fi)
DK (1) DK358784A (fi)
ES (1) ES534509A0 (fi)
FI (1) FI86987C (fi)
GR (1) GR82234B (fi)
HK (1) HK142395A (fi)
HU (1) HU194832B (fi)
IE (1) IE57627B1 (fi)
IL (1) IL72471A (fi)
NO (1) NO167510C (fi)
NZ (1) NZ208966A (fi)
PT (1) PT78960B (fi)
SU (2) SU1393314A3 (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4889862A (en) * 1986-08-28 1989-12-26 E. I. Du Pont De Nemours And Company Freeze-dried pharmaceutical compositions of phenylquinoline carboxylic acids
HUT55742A (en) * 1987-12-28 1991-06-28 Dowelanco Process for producing (phenoxy-phenoxy)-propionate derivatives and theyr new intermediates
US4861783A (en) * 1988-04-26 1989-08-29 E. I. Du Pont De Nemours And Company 4-quinoline carboxylic acid derivatives useful for treating skin and muco-epithelial diseases
US4968702A (en) * 1989-01-17 1990-11-06 American Cyanamid Company Substituted quinolinecarboxylic acids
US4918077A (en) * 1989-01-25 1990-04-17 E. I. Du Pont De Nemours & Co., Inc. 3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents
DE3905339A1 (de) * 1989-02-22 1990-09-06 Basf Ag Chinolin-4-carbonsaeurederivate und deren verwendung
US5393891A (en) * 1993-06-08 1995-02-28 The Du Pont Merck Pharmaceutical Company Immunoassay reagents and methods for detecting brequinar and analogs
AU751188C (en) * 1997-05-28 2005-06-30 Aventis Pharmaceuticals Inc. Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases
AU2201699A (en) * 1997-12-19 1999-07-12 Eli Lilly And Company Hypoglycemic imidazoline compounds
WO2004002484A1 (ja) * 2002-06-26 2004-01-08 Kyowa Hakko Kogyo Co., Ltd. ホスホジエステラーゼ阻害剤
US8232310B2 (en) 2006-12-29 2012-07-31 Georgetown University Targeting of EWS-FLI1 as anti-tumor therapy
EP2836481B1 (en) 2012-04-12 2018-12-26 Georgetown University Compounds and compositions for treating ewings sarcoma family of tumors
RU2016114498A (ru) 2013-10-24 2017-11-29 Джорджтаун Юниверсити Способы и композиции для лечения раковых заболеваний
EA201691057A1 (ru) 2013-11-22 2016-10-31 Джензим Корпорейшн Новые способы лечения нейродегенеративных заболеваний
MX2017003589A (es) 2014-10-09 2018-08-15 Oncternal Therapeutics Inc Compuestos de indolinona y usos de los mismos.
JP6864379B2 (ja) 2016-03-31 2021-04-28 オンターナル セラピューティック インコーポレイテッドOncternal Therapeutics, Inc. インドール類似体及びその使用
US10159660B2 (en) 2016-07-29 2018-12-25 Oncternal Therapeutics, Inc. Uses of indolinone compounds
AU2020411507A1 (en) * 2019-12-26 2022-07-14 Hendrix College Methods and compositions for inhibition of dihydroorotate dehydrogenase

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE502610A (fi) * 1950-04-18
US2888346A (en) * 1955-08-22 1959-05-26 Gen Aniline & Film Corp Ultra-violet absorbing compounds

Also Published As

Publication number Publication date
AU3085284A (en) 1985-01-24
EP0133244A2 (en) 1985-02-20
HUT35248A (en) 1985-06-28
PT78960A (en) 1984-08-01
FI86987C (fi) 1992-11-10
DK358784A (da) 1985-01-23
ES8507498A1 (es) 1985-09-01
AU583793B2 (en) 1989-05-11
CA1288436C (en) 1991-09-03
NZ208966A (en) 1986-12-05
NO842969L (no) 1985-01-23
DK358784D0 (da) 1984-07-20
NO167510B (no) 1991-08-05
DE3483704D1 (de) 1991-01-17
IE841873L (en) 1985-01-22
NO167510C (no) 1991-11-13
SU1452480A3 (ru) 1989-01-15
EP0133244B1 (en) 1990-12-05
IL72471A (en) 1988-11-15
IL72471A0 (en) 1984-11-30
FI86987B (fi) 1992-07-31
HK142395A (en) 1995-09-15
SU1393314A3 (ru) 1988-04-30
EP0133244A3 (en) 1985-12-11
ES534509A0 (es) 1985-09-01
FI842928A0 (fi) 1984-07-20
GR82234B (fi) 1984-12-13
IE57627B1 (en) 1993-02-10
HU194832B (en) 1988-03-28
PT78960B (en) 1986-10-20

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Owner name: THE DU PONT MERCK PHARMACEUTICAL COMPANY