DK358784A - Phenylquinolincarboxylsyrer, derivater og salte deraf, deres fremstilling og anvendelse i antitumormidler - Google Patents
Phenylquinolincarboxylsyrer, derivater og salte deraf, deres fremstilling og anvendelse i antitumormidler Download PDFInfo
- Publication number
- DK358784A DK358784A DK358784A DK358784A DK358784A DK 358784 A DK358784 A DK 358784A DK 358784 A DK358784 A DK 358784A DK 358784 A DK358784 A DK 358784A DK 358784 A DK358784 A DK 358784A
- Authority
- DK
- Denmark
- Prior art keywords
- phenylquinolincarboxylic
- antitumum
- derivatives
- salts
- acids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
- C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51631983A | 1983-07-22 | 1983-07-22 | |
| US60510484A | 1984-04-30 | 1984-04-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK358784D0 DK358784D0 (da) | 1984-07-20 |
| DK358784A true DK358784A (da) | 1985-01-23 |
Family
ID=27058797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK358784A DK358784A (da) | 1983-07-22 | 1984-07-20 | Phenylquinolincarboxylsyrer, derivater og salte deraf, deres fremstilling og anvendelse i antitumormidler |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0133244B1 (da) |
| AU (1) | AU583793B2 (da) |
| CA (1) | CA1288436C (da) |
| DE (1) | DE3483704D1 (da) |
| DK (1) | DK358784A (da) |
| ES (1) | ES534509A0 (da) |
| FI (1) | FI86987C (da) |
| GR (1) | GR82234B (da) |
| HK (1) | HK142395A (da) |
| HU (1) | HU194832B (da) |
| IE (1) | IE57627B1 (da) |
| IL (1) | IL72471A (da) |
| NO (1) | NO167510C (da) |
| NZ (1) | NZ208966A (da) |
| PT (1) | PT78960B (da) |
| SU (2) | SU1393314A3 (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4889862A (en) * | 1986-08-28 | 1989-12-26 | E. I. Du Pont De Nemours And Company | Freeze-dried pharmaceutical compositions of phenylquinoline carboxylic acids |
| AU611255B2 (en) * | 1987-12-28 | 1991-06-06 | Dowelanco | Phenoxyphenoxypropionates, intermediates thereof and methods of preparation |
| US4861783A (en) * | 1988-04-26 | 1989-08-29 | E. I. Du Pont De Nemours And Company | 4-quinoline carboxylic acid derivatives useful for treating skin and muco-epithelial diseases |
| US4968702A (en) * | 1989-01-17 | 1990-11-06 | American Cyanamid Company | Substituted quinolinecarboxylic acids |
| US4918077A (en) * | 1989-01-25 | 1990-04-17 | E. I. Du Pont De Nemours & Co., Inc. | 3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents |
| DE3905339A1 (de) * | 1989-02-22 | 1990-09-06 | Basf Ag | Chinolin-4-carbonsaeurederivate und deren verwendung |
| US5393891A (en) * | 1993-06-08 | 1995-02-28 | The Du Pont Merck Pharmaceutical Company | Immunoassay reagents and methods for detecting brequinar and analogs |
| ATE286886T1 (de) * | 1997-05-28 | 2005-01-15 | Aventis Pharma Inc | Chinolin- und chinoxalin-verbindungen die den von blutplättchen abstammmenden wachstumsfaktor und/oder pdgf- und p56lck-tyrosin-kinase hemmen |
| DK0924209T3 (da) * | 1997-12-19 | 2003-08-25 | Lilly Co Eli | Hypoglykæmiske imidazolinforbindelser |
| AU2003244080A1 (en) * | 2002-06-26 | 2004-01-19 | Kyowa Hakko Kogyo Co., Ltd. | Phosphodiesterase inhibitor |
| US8232310B2 (en) | 2006-12-29 | 2012-07-31 | Georgetown University | Targeting of EWS-FLI1 as anti-tumor therapy |
| NZ723971A (en) | 2012-04-12 | 2018-01-26 | Univ Georgetown | Methods and compositions for treating ewings sarcoma family of tumors |
| KR20160065986A (ko) | 2013-10-24 | 2016-06-09 | 조지타운 유니버시티 | 암 치료용 방법 및 조성물 |
| KR20160079123A (ko) | 2013-11-22 | 2016-07-05 | 젠자임 코포레이션 | 신경변성 질병을 치료하기 위한 신규한 방법 |
| CN111777596A (zh) | 2014-10-09 | 2020-10-16 | 英克特诺治疗公司 | 吲哚酮化合物及其用途 |
| CN109219594B (zh) | 2016-03-31 | 2022-10-11 | 英克特诺治疗公司 | 吲哚啉类似物及其用途 |
| CA3029851A1 (en) | 2016-07-29 | 2018-02-01 | Oncternal Therapeutics, Inc. | Uses of indoline compounds such as tk216 for the treatment of cancer |
| WO2021134042A1 (en) * | 2019-12-26 | 2021-07-01 | Ohio State Innovation Foundation | Methods and compositions for inhibition of dihydroorotate dehydrogenase |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE502610A (da) * | 1950-04-18 | |||
| US2888346A (en) * | 1955-08-22 | 1959-05-26 | Gen Aniline & Film Corp | Ultra-violet absorbing compounds |
-
1984
- 1984-07-19 CA CA000459263A patent/CA1288436C/en not_active Expired - Lifetime
- 1984-07-19 AU AU30852/84A patent/AU583793B2/en not_active Ceased
- 1984-07-19 DE DE8484108523T patent/DE3483704D1/de not_active Expired - Lifetime
- 1984-07-19 EP EP84108523A patent/EP0133244B1/en not_active Expired - Lifetime
- 1984-07-20 FI FI842928A patent/FI86987C/fi not_active IP Right Cessation
- 1984-07-20 ES ES534509A patent/ES534509A0/es active Granted
- 1984-07-20 DK DK358784A patent/DK358784A/da not_active Application Discontinuation
- 1984-07-20 HU HU842824A patent/HU194832B/hu not_active IP Right Cessation
- 1984-07-20 SU SU843776940A patent/SU1393314A3/ru active
- 1984-07-20 IE IE1873/84A patent/IE57627B1/en not_active IP Right Cessation
- 1984-07-20 PT PT78960A patent/PT78960B/pt not_active IP Right Cessation
- 1984-07-20 NO NO842969A patent/NO167510C/no unknown
- 1984-07-20 NZ NZ208966A patent/NZ208966A/en unknown
- 1984-07-20 IL IL72471A patent/IL72471A/xx not_active IP Right Cessation
- 1984-07-20 GR GR75386A patent/GR82234B/el unknown
-
1986
- 1986-01-06 SU SU864000869A patent/SU1452480A3/ru active
-
1995
- 1995-09-07 HK HK142395A patent/HK142395A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HK142395A (en) | 1995-09-15 |
| NO167510C (no) | 1991-11-13 |
| SU1452480A3 (ru) | 1989-01-15 |
| FI86987C (fi) | 1992-11-10 |
| FI86987B (fi) | 1992-07-31 |
| GR82234B (da) | 1984-12-13 |
| AU3085284A (en) | 1985-01-24 |
| IL72471A (en) | 1988-11-15 |
| HU194832B (en) | 1988-03-28 |
| AU583793B2 (en) | 1989-05-11 |
| NZ208966A (en) | 1986-12-05 |
| DK358784D0 (da) | 1984-07-20 |
| EP0133244B1 (en) | 1990-12-05 |
| EP0133244A2 (en) | 1985-02-20 |
| IE841873L (en) | 1985-01-22 |
| ES8507498A1 (es) | 1985-09-01 |
| HUT35248A (en) | 1985-06-28 |
| NO167510B (no) | 1991-08-05 |
| EP0133244A3 (en) | 1985-12-11 |
| FI842928A (fi) | 1985-01-23 |
| PT78960A (en) | 1984-08-01 |
| ES534509A0 (es) | 1985-09-01 |
| PT78960B (en) | 1986-10-20 |
| SU1393314A3 (ru) | 1988-04-30 |
| FI842928A0 (fi) | 1984-07-20 |
| NO842969L (no) | 1985-01-23 |
| IE57627B1 (en) | 1993-02-10 |
| CA1288436C (en) | 1991-09-03 |
| IL72471A0 (en) | 1984-11-30 |
| DE3483704D1 (de) | 1991-01-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |