DK69389D0 - Renin-haemmende aminosyrederivater og fysiologisk acceptable salte deraf, deres fremstilling og anvendelse - Google Patents

Renin-haemmende aminosyrederivater og fysiologisk acceptable salte deraf, deres fremstilling og anvendelse

Info

Publication number
DK69389D0
DK69389D0 DK069389A DK69389A DK69389D0 DK 69389 D0 DK69389 D0 DK 69389D0 DK 069389 A DK069389 A DK 069389A DK 69389 A DK69389 A DK 69389A DK 69389 D0 DK69389 D0 DK 69389D0
Authority
DK
Denmark
Prior art keywords
physially
pure
preparation
amino acid
acceptable salts
Prior art date
Application number
DK069389A
Other languages
English (en)
Other versions
DK69389A (da
Inventor
Rainer Henning
Hansjoerg Urbach
Dieter Ruppert
Bernward Schoelkens
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK69389D0 publication Critical patent/DK69389D0/da
Publication of DK69389A publication Critical patent/DK69389A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
DK069389A 1988-02-16 1989-02-15 Renin-haemmende aminosyrederivater og fysiologisk acceptable salte deraf, deres fremstilling og anvendelse DK69389A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3804793A DE3804793A1 (de) 1988-02-16 1988-02-16 Renin-hemmende aminosaeurederivate

Publications (2)

Publication Number Publication Date
DK69389D0 true DK69389D0 (da) 1989-02-15
DK69389A DK69389A (da) 1989-08-17

Family

ID=6347510

Family Applications (1)

Application Number Title Priority Date Filing Date
DK069389A DK69389A (da) 1988-02-16 1989-02-15 Renin-haemmende aminosyrederivater og fysiologisk acceptable salte deraf, deres fremstilling og anvendelse

Country Status (15)

Country Link
US (1) US5204357A (da)
EP (1) EP0329013A3 (da)
JP (1) JPH023665A (da)
KR (1) KR890013053A (da)
CN (1) CN1035286A (da)
AU (1) AU626535B2 (da)
DE (1) DE3804793A1 (da)
DK (1) DK69389A (da)
FI (1) FI890699A (da)
HU (1) HU203226B (da)
IL (1) IL89304A0 (da)
NO (1) NO890635L (da)
NZ (1) NZ227976A (da)
PT (1) PT89730B (da)
ZA (1) ZA891135B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3717631A1 (de) * 1987-05-26 1988-12-15 Merck Patent Gmbh Aminosaeurederivate
ES2086341T3 (es) * 1989-09-12 1996-07-01 Hoechst Ag Derivados de aminoacidos con propiedades inhibidoras de la renina, procedimiento para su preparacion, agentes que los contienen y su utilizacion.
EP0432974A1 (en) * 1989-12-08 1991-06-19 Merck & Co. Inc. Cyclic renin inhibitors
US5330737A (en) * 1991-12-06 1994-07-19 Mallinckrodt Medical, Inc. Nitrogen-sulfur ligands as opiate receptor drug mimics
US6455734B1 (en) 2000-08-09 2002-09-24 Magnesium Diagnostics, Inc. Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states
CA2894126A1 (en) 2012-12-21 2014-06-26 Epizyme, Inc. Prmt5 inhibitors and uses thereof
EP3406607A1 (en) 2012-12-21 2018-11-28 Epizyme, Inc. Prmt5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof
WO2014100716A1 (en) 2012-12-21 2014-06-26 Epizyme, Inc. Prmt5 inhibitors and uses thereof
KR102173874B1 (ko) 2012-12-21 2020-11-05 에피자임, 인코포레이티드 테트라하이드로- 및 디하이드로-이소퀴놀린 prmt5 억제제 및 이의 용도
EP2935247B1 (en) 2012-12-21 2019-08-28 Epizyme, Inc. Prmt5 inhibitors and uses thereof
CA2953572A1 (en) 2014-08-04 2016-02-11 Epizyme, Inc. Prmt5 inhibitors and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4435329A (en) * 1981-10-16 1984-03-06 American Cyanamid Company Substituted N-(ω-aroylpropionyl) derivatives of α-amino acids and esters thereof
EP0136883B1 (en) * 1983-10-03 1987-11-25 E.R. Squibb & Sons, Inc. Enkephalinase inhibitors
EP0236734A3 (de) * 1986-02-07 1988-05-11 Ciba-Geigy Ag Durch schwefelhaltigen Gruppen substituierte 5-Amino-4-hydroxyvalerylderivate
DE3732971A1 (de) * 1987-09-30 1989-04-20 Hoechst Ag Renin-hemmende dipeptide, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung

Also Published As

Publication number Publication date
DK69389A (da) 1989-08-17
AU2997789A (en) 1989-08-17
AU626535B2 (en) 1992-08-06
NO890635D0 (no) 1989-02-15
NZ227976A (en) 1991-12-23
FI890699A0 (fi) 1989-02-14
EP0329013A3 (de) 1991-03-13
NO890635L (no) 1989-08-17
CN1035286A (zh) 1989-09-06
US5204357A (en) 1993-04-20
HU203226B (en) 1991-06-28
IL89304A0 (en) 1989-09-10
KR890013053A (ko) 1989-09-21
ZA891135B (en) 1989-10-25
FI890699A (fi) 1989-08-17
PT89730B (pt) 1994-03-31
PT89730A (pt) 1989-10-04
EP0329013A2 (de) 1989-08-23
HUT50789A (en) 1990-03-28
DE3804793A1 (de) 1989-08-24
JPH023665A (ja) 1990-01-09

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Legal Events

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