ZA891135B - Renin-inhibiting amino acid derivatives - Google Patents
Renin-inhibiting amino acid derivativesInfo
- Publication number
- ZA891135B ZA891135B ZA891135A ZA891135A ZA891135B ZA 891135 B ZA891135 B ZA 891135B ZA 891135 A ZA891135 A ZA 891135A ZA 891135 A ZA891135 A ZA 891135A ZA 891135 B ZA891135 B ZA 891135B
- Authority
- ZA
- South Africa
- Prior art keywords
- renin
- amino acid
- acid derivatives
- inhibiting amino
- inhibiting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyridine Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3804793A DE3804793A1 (de) | 1988-02-16 | 1988-02-16 | Renin-hemmende aminosaeurederivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA891135B true ZA891135B (en) | 1989-10-25 |
Family
ID=6347510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA891135A ZA891135B (en) | 1988-02-16 | 1989-02-14 | Renin-inhibiting amino acid derivatives |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5204357A (xx) |
| EP (1) | EP0329013A3 (xx) |
| JP (1) | JPH023665A (xx) |
| KR (1) | KR890013053A (xx) |
| CN (1) | CN1035286A (xx) |
| AU (1) | AU626535B2 (xx) |
| DE (1) | DE3804793A1 (xx) |
| DK (1) | DK69389A (xx) |
| FI (1) | FI890699A (xx) |
| HU (1) | HU203226B (xx) |
| IL (1) | IL89304A0 (xx) |
| NO (1) | NO890635L (xx) |
| NZ (1) | NZ227976A (xx) |
| PT (1) | PT89730B (xx) |
| ZA (1) | ZA891135B (xx) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3717631A1 (de) * | 1987-05-26 | 1988-12-15 | Merck Patent Gmbh | Aminosaeurederivate |
| DE4028741A1 (de) * | 1989-09-12 | 1991-03-28 | Hoechst Ag | Aminosaeurederivate mit reninhemmenden eigenschaften, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung |
| EP0432974A1 (en) * | 1989-12-08 | 1991-06-19 | Merck & Co. Inc. | Cyclic renin inhibitors |
| US5330737A (en) * | 1991-12-06 | 1994-07-19 | Mallinckrodt Medical, Inc. | Nitrogen-sulfur ligands as opiate receptor drug mimics |
| US6455734B1 (en) | 2000-08-09 | 2002-09-24 | Magnesium Diagnostics, Inc. | Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states |
| JP2016505000A (ja) | 2012-12-21 | 2016-02-18 | エピザイム，インコーポレイティド | Ｐｒｍｔ５阻害剤およびその使用 |
| CA2899363A1 (en) | 2012-12-21 | 2014-06-26 | Epizyme, Inc. | Prmt5 inhibitors and uses thereof |
| EP2935247B1 (en) | 2012-12-21 | 2019-08-28 | Epizyme, Inc. | Prmt5 inhibitors and uses thereof |
| EP2935243B1 (en) | 2012-12-21 | 2018-03-14 | Epizyme, Inc. | Prmt5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof |
| JP6678455B2 (ja) | 2012-12-21 | 2020-04-08 | エピザイム，インコーポレイティド | Ｐｒｍｔ５阻害剤およびその使用 |
| CA2953572A1 (en) | 2014-08-04 | 2016-02-11 | Epizyme, Inc. | Prmt5 inhibitors and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4435329A (en) * | 1981-10-16 | 1984-03-06 | American Cyanamid Company | Substituted N-(ω-aroylpropionyl) derivatives of α-amino acids and esters thereof |
| EP0136883B1 (en) * | 1983-10-03 | 1987-11-25 | E.R. Squibb & Sons, Inc. | Enkephalinase inhibitors |
| FI870474A (fi) * | 1986-02-07 | 1987-08-08 | Ciba Geigy Ag | Med svavelhaltiga grupper substituerade 5-amino-4-hydroxivalerylderivat. |
| DE3732971A1 (de) * | 1987-09-30 | 1989-04-20 | Hoechst Ag | Renin-hemmende dipeptide, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung |
-
1988
- 1988-02-16 DE DE3804793A patent/DE3804793A1/de not_active Withdrawn
-
1989
- 1989-02-09 EP EP19890102215 patent/EP0329013A3/de not_active Withdrawn
- 1989-02-14 ZA ZA891135A patent/ZA891135B/xx unknown
- 1989-02-14 FI FI890699A patent/FI890699A/fi not_active Application Discontinuation
- 1989-02-14 US US07/310,183 patent/US5204357A/en not_active Expired - Fee Related
- 1989-02-14 NZ NZ227976A patent/NZ227976A/xx unknown
- 1989-02-15 JP JP1033895A patent/JPH023665A/ja active Pending
- 1989-02-15 IL IL89304A patent/IL89304A0/xx not_active IP Right Cessation
- 1989-02-15 KR KR1019890001707A patent/KR890013053A/ko not_active Application Discontinuation
- 1989-02-15 AU AU29977/89A patent/AU626535B2/en not_active Ceased
- 1989-02-15 CN CN89100812A patent/CN1035286A/zh active Pending
- 1989-02-15 HU HU89763A patent/HU203226B/hu not_active IP Right Cessation
- 1989-02-15 NO NO89890635A patent/NO890635L/no unknown
- 1989-02-15 DK DK069389A patent/DK69389A/da not_active Application Discontinuation
- 1989-02-16 PT PT89730A patent/PT89730B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL89304A0 (en) | 1989-09-10 |
| DK69389A (da) | 1989-08-17 |
| EP0329013A3 (de) | 1991-03-13 |
| FI890699A (fi) | 1989-08-17 |
| EP0329013A2 (de) | 1989-08-23 |
| NO890635L (no) | 1989-08-17 |
| DE3804793A1 (de) | 1989-08-24 |
| DK69389D0 (da) | 1989-02-15 |
| AU626535B2 (en) | 1992-08-06 |
| NZ227976A (en) | 1991-12-23 |
| PT89730A (pt) | 1989-10-04 |
| KR890013053A (ko) | 1989-09-21 |
| PT89730B (pt) | 1994-03-31 |
| US5204357A (en) | 1993-04-20 |
| FI890699A0 (fi) | 1989-02-14 |
| CN1035286A (zh) | 1989-09-06 |
| AU2997789A (en) | 1989-08-17 |
| NO890635D0 (no) | 1989-02-15 |
| HU203226B (en) | 1991-06-28 |
| HUT50789A (en) | 1990-03-28 |
| JPH023665A (ja) | 1990-01-09 |
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