ZA892059B - Amino acid derivatives - Google Patents

Amino acid derivatives

Info

Publication number
ZA892059B
ZA892059B ZA892059A ZA892059A ZA892059B ZA 892059 B ZA892059 B ZA 892059B ZA 892059 A ZA892059 A ZA 892059A ZA 892059 A ZA892059 A ZA 892059A ZA 892059 B ZA892059 B ZA 892059B
Authority
ZA
South Africa
Prior art keywords
amino acid
acid derivatives
derivatives
amino
acid
Prior art date
Application number
ZA892059A
Inventor
Peter Raddatz
Raddatz Peter
Johannes Sombroek
Sombroek Johannes
Joachim Gante
Gante Joachim
Claus J Schmitges
J Schmitges Claus
Klaus-Otto Minck
Minck Klaus-Otto
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA892059B publication Critical patent/ZA892059B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
ZA892059A 1988-03-18 1989-03-17 Amino acid derivatives ZA892059B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3809145A DE3809145A1 (en) 1988-03-18 1988-03-18 AMINOSAEUREDERIVATE

Publications (1)

Publication Number Publication Date
ZA892059B true ZA892059B (en) 1989-11-29

Family

ID=6350109

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA892059A ZA892059B (en) 1988-03-18 1989-03-17 Amino acid derivatives

Country Status (7)

Country Link
EP (1) EP0342325A3 (en)
JP (1) JPH024749A (en)
KR (1) KR890014580A (en)
AU (1) AU626835B2 (en)
DE (1) DE3809145A1 (en)
HU (1) HU203116B (en)
ZA (1) ZA892059B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3717631A1 (en) * 1987-05-26 1988-12-15 Merck Patent Gmbh AMINO ACID DERIVATIVES
WO1993009132A1 (en) * 1991-11-01 1993-05-13 Smithkline Beecham Corporation Hiv protease inhibitors containing guanidine
US6797820B2 (en) 1999-12-17 2004-09-28 Vicuron Pharmaceuticals Inc. Succinate compounds, compositions and methods of use and preparation
JP4679981B2 (en) * 2005-07-01 2011-05-11 エヌ・イーケムキャット株式会社 Method for deprotecting 9-fluorenylmethoxycarbonyl group

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4727060A (en) * 1984-11-13 1988-02-23 Ciba-Geigy Corporation Novel 5-amino-4-hydroxyvaleryl derivatives
ATE116994T1 (en) * 1986-06-10 1995-01-15 Merck Patent Gmbh RENIN-INHIBITING AMINO ACID DERIVATIVES.
EP0274259B1 (en) * 1986-12-19 1994-02-16 Sankyo Company Limited New renin-inhibitory oligopeptides, their preparaton and their use

Also Published As

Publication number Publication date
KR890014580A (en) 1989-10-24
AU3119989A (en) 1989-09-21
HUT53121A (en) 1990-09-28
JPH024749A (en) 1990-01-09
DE3809145A1 (en) 1989-09-28
EP0342325A3 (en) 1991-01-16
HU203116B (en) 1991-05-28
AU626835B2 (en) 1992-08-13
EP0342325A2 (en) 1989-11-23

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