ZA883782B - Amino acid derivatives - Google Patents

Amino acid derivatives

Info

Publication number
ZA883782B
ZA883782B ZA883782A ZA883782A ZA883782B ZA 883782 B ZA883782 B ZA 883782B ZA 883782 A ZA883782 A ZA 883782A ZA 883782 A ZA883782 A ZA 883782A ZA 883782 B ZA883782 B ZA 883782B
Authority
ZA
South Africa
Prior art keywords
amino acid
acid derivatives
derivatives
amino
acid
Prior art date
Application number
ZA883782A
Inventor
Peter Raddatz
Raddatz Peter
Johannes Sombroek
Sombroek Johannes
Joachim Gante
Gante Joachim
Claus J Schmitges
J Schmitges Claus
Klaus Otto Minck
Otto Minck Klaus
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA883782B publication Critical patent/ZA883782B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/021—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
ZA883782A 1987-05-26 1988-05-26 Amino acid derivatives ZA883782B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873717631 DE3717631A1 (en) 1987-05-26 1987-05-26 AMINO ACID DERIVATIVES

Publications (1)

Publication Number Publication Date
ZA883782B true ZA883782B (en) 1989-01-25

Family

ID=6328389

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA883782A ZA883782B (en) 1987-05-26 1988-05-26 Amino acid derivatives

Country Status (7)

Country Link
EP (1) EP0292800A3 (en)
JP (1) JPH01163164A (en)
KR (1) KR880013902A (en)
AU (1) AU610588B2 (en)
DE (1) DE3717631A1 (en)
HU (1) HU205951B (en)
ZA (1) ZA883782B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340588C (en) * 1988-06-13 1999-06-08 Balraj Krishan Handa Amino acid derivatives
CA2010531A1 (en) * 1989-03-06 1990-09-06 Werner Neidhart Amino acid derivatives
DE3913290A1 (en) * 1989-04-22 1990-10-25 Hoechst Ag RENIN-INHIBITING DI- AND TRIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THE MEANS CONTAINING THEM AND THEIR USE
DE4033062A1 (en) * 1990-10-18 1992-04-23 Merck Patent Gmbh AMINOSAEUREDERIVATE
GB8927913D0 (en) * 1989-12-11 1990-02-14 Hoffmann La Roche Amino acid derivatives
DE4021512A1 (en) * 1990-07-05 1992-01-16 Merck Patent Gmbh AMINOSAEUREDERIVATE

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2561733B1 (en) * 1984-03-20 1986-08-22 Peugeot TUBULAR TORSION BAR
DE3418491A1 (en) * 1984-05-18 1985-11-21 Merck Patent Gmbh, 6100 Darmstadt DIAMINO ACID DERIVATIVES
EP0163237A3 (en) * 1984-05-29 1988-04-27 Merck & Co. Inc. Di- and tri-peptidal renin inhibitors
DE3438545A1 (en) * 1984-10-20 1986-04-24 Merck Patent Gmbh, 6100 Darmstadt PEPTIDE
DE3538749A1 (en) * 1985-10-31 1987-05-07 Merck Patent Gmbh PEPTIDE
DE3540495A1 (en) * 1985-11-15 1987-05-21 Merck Patent Gmbh AMINO ACID DERIVATIVES
ES2066755T3 (en) * 1986-06-10 1995-03-16 Merck Patent Gmbh DERIVATIVES OF RENINE INHIBITING AMINO ACIDS.
DE3635907A1 (en) * 1986-10-22 1988-04-28 Merck Patent Gmbh HYDROXY AMINO ACID DERIVATIVES
DE3804793A1 (en) * 1988-02-16 1989-08-24 Hoechst Ag RENIN-INHIBITING AMINOSAUTE DERIVATIVES
DE3809145A1 (en) * 1988-03-18 1989-09-28 Merck Patent Gmbh AMINOSAEUREDERIVATE
DE3812328A1 (en) * 1988-04-14 1989-10-26 Merck Patent Gmbh AMINOSAEUREDERIVATE

Also Published As

Publication number Publication date
EP0292800A2 (en) 1988-11-30
KR880013902A (en) 1988-12-22
HUT49148A (en) 1989-08-28
JPH01163164A (en) 1989-06-27
EP0292800A3 (en) 1990-11-22
HU205951B (en) 1992-07-28
AU1630088A (en) 1989-02-16
DE3717631A1 (en) 1988-12-15
AU610588B2 (en) 1991-05-23

Similar Documents

Publication Publication Date Title
ZA877950B (en) Amino acid derivatives
ZA902185B (en) Amino acid derivatives
EP0416373A3 (en) Amino acid derivatives
AU1261788A (en) Amino acid derivatives
ZA882347B (en) Amino acid derivatives
ZA887322B (en) Amino acid derivatives
EP0231996A3 (en) Novel amino acid derivatives
ZA875692B (en) Amino acid derivatives
ZA893199B (en) Amino acid derivatives
ZA887373B (en) Amino acid derivatives
ZA892720B (en) Amino acid derivatives
ZA883782B (en) Amino acid derivatives
ZA899114B (en) Amino acid derivatives
ZA892059B (en) Amino acid derivatives
ZA902395B (en) Amino acid derivatives
GB8707515D0 (en) Amino acid derivatives
ZA891265B (en) Amino acid derivatives
IE871528L (en) Amino acid derivatives
IE872080L (en) Amino acid derivatives
IE870513L (en) Amino acid derivatives
IE870512L (en) Amino acid derivatives
IE872833L (en) Amino acid derivatives
ZA881782B (en) Amino acid derivatives
IE860546L (en) Amino acid derivatives
IE863019L (en) Amino acid derivatives