ZA893199B - Amino acid derivatives - Google Patents

Amino acid derivatives

Info

Publication number
ZA893199B
ZA893199B ZA893199A ZA893199A ZA893199B ZA 893199 B ZA893199 B ZA 893199B ZA 893199 A ZA893199 A ZA 893199A ZA 893199 A ZA893199 A ZA 893199A ZA 893199 B ZA893199 B ZA 893199B
Authority
ZA
South Africa
Prior art keywords
amino acid
acid derivatives
derivatives
amino
acid
Prior art date
Application number
ZA893199A
Inventor
Peter Raddatz
Raddatz Peter
Claus J Schmitges
J Schmitges Claus
Klaus-Otto Minck
Minck Klaus-Otto
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA893199B publication Critical patent/ZA893199B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/021—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06156—Dipeptides with the first amino acid being heterocyclic and Trp-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA893199A 1988-04-28 1989-04-28 Amino acid derivatives ZA893199B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3814325A DE3814325A1 (en) 1988-04-28 1988-04-28 AMINOSAEUREDERIVATE

Publications (1)

Publication Number Publication Date
ZA893199B true ZA893199B (en) 1990-01-31

Family

ID=6353067

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA893199A ZA893199B (en) 1988-04-28 1989-04-28 Amino acid derivatives

Country Status (7)

Country Link
EP (1) EP0339483A3 (en)
JP (1) JPH0211548A (en)
KR (1) KR890016063A (en)
AU (1) AU618340B2 (en)
DE (1) DE3814325A1 (en)
HU (1) HU208427B (en)
ZA (1) ZA893199B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63261449A (en) * 1987-04-20 1988-10-28 Hitachi Ltd Data processor
DE3841520A1 (en) * 1988-12-09 1990-06-13 Hoechst Ag ENZYME-INFRINGING DERIVATIVES OF DIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, METHODS CONTAINING THEM AND THEIR USE
TW209870B (en) * 1990-01-18 1993-07-21 Pfizer
DE4003575A1 (en) * 1990-02-07 1991-08-08 Bayer Ag RETROISOSTERIC DIPEPTIDES, METHOD FOR THE PREPARATION AND THEIR USE AS RENININHIBITORS IN MEDICAMENTS
EP0483403A1 (en) * 1990-10-31 1992-05-06 Hoechst Aktiengesellschaft Derivatives of amino acids as inhibitors of renin, methods for their preparation, medicaments containing them and their use
US5442044A (en) * 1991-01-04 1995-08-15 Pfizer Inc. Orally active renin inhibitors
US5986102A (en) * 1998-04-29 1999-11-16 Pharmacopeia, Inc. Hydroxypropylamide peptidomimetics as inhibitors of aspartyl proteases
WO2004040306A1 (en) * 2002-10-31 2004-05-13 Labrea Holding S.A. Diagnostic device and kit
CN103402264B (en) 2007-08-14 2017-06-06 松下电器产业株式会社 Base station apparatus, integrated circuit and communication means

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02500025A (en) * 1986-09-30 1990-01-11 ジ・アップジョン・カンパニー Renin inhibitory peptide with a novel C-terminal group
DE3635907A1 (en) * 1986-10-22 1988-04-28 Merck Patent Gmbh HYDROXY AMINO ACID DERIVATIVES
DE3732971A1 (en) * 1987-09-30 1989-04-20 Hoechst Ag RENINE INHIBITING DIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THE AGENTS CONTAINING THEM AND THEIR USE
DE3733296A1 (en) * 1987-10-02 1989-04-20 Merck Patent Gmbh AMINOSAEUREDERIVATE

Also Published As

Publication number Publication date
JPH0211548A (en) 1990-01-16
DE3814325A1 (en) 1989-11-09
HUT53663A (en) 1990-11-28
AU618340B2 (en) 1991-12-19
EP0339483A3 (en) 1990-09-19
HU208427B (en) 1993-10-28
AU3329289A (en) 1989-11-02
KR890016063A (en) 1989-11-28
EP0339483A2 (en) 1989-11-02

Similar Documents

Publication Publication Date Title
ZA902185B (en) Amino acid derivatives
EP0416373A3 (en) Amino acid derivatives
ZA882347B (en) Amino acid derivatives
ZA887322B (en) Amino acid derivatives
ZA902444B (en) Amino acid derivatives
ZA893199B (en) Amino acid derivatives
ZA892720B (en) Amino acid derivatives
ZA887373B (en) Amino acid derivatives
ZA883782B (en) Amino acid derivatives
ZA899114B (en) Amino acid derivatives
ZA892059B (en) Amino acid derivatives
ZA902395B (en) Amino acid derivatives
ZA891265B (en) Amino acid derivatives
GB8707515D0 (en) Amino acid derivatives
ZA907585B (en) Amino acid derivatives
ZA894285B (en) Amino acid derivatives
ZA891659B (en) Amino acid derivatives
ZA891464B (en) Amino acid derivatives
IE882767L (en) Amino acid derivatives
IE880986L (en) Amino acid derivatives
HRP930443B1 (en) Amino acid derivatives
ZA89906B (en) Amino acid derivatives
IE891189L (en) Amino acid derivatives
IE890698L (en) Amino acid derivatives
IE893804L (en) Amino acid derivatives