GR82234B - - Google Patents

Info

Publication number
GR82234B
GR82234B GR75386A GR840175386A GR82234B GR 82234 B GR82234 B GR 82234B GR 75386 A GR75386 A GR 75386A GR 840175386 A GR840175386 A GR 840175386A GR 82234 B GR82234 B GR 82234B
Authority
GR
Greece
Application number
GR75386A
Inventor
David Paul Hesson
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of GR82234B publication Critical patent/GR82234B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/50Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
    • C07D215/52Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GR75386A 1983-07-22 1984-07-20 GR82234B (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51631983A 1983-07-22 1983-07-22
US60510484A 1984-04-30 1984-04-30

Publications (1)

Publication Number Publication Date
GR82234B true GR82234B (el) 1984-12-13

Family

ID=27058797

Family Applications (1)

Application Number Title Priority Date Filing Date
GR75386A GR82234B (el) 1983-07-22 1984-07-20

Country Status (16)

Country Link
EP (1) EP0133244B1 (el)
AU (1) AU583793B2 (el)
CA (1) CA1288436C (el)
DE (1) DE3483704D1 (el)
DK (1) DK358784A (el)
ES (1) ES8507498A1 (el)
FI (1) FI86987C (el)
GR (1) GR82234B (el)
HK (1) HK142395A (el)
HU (1) HU194832B (el)
IE (1) IE57627B1 (el)
IL (1) IL72471A (el)
NO (1) NO167510C (el)
NZ (1) NZ208966A (el)
PT (1) PT78960B (el)
SU (2) SU1393314A3 (el)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4889862A (en) * 1986-08-28 1989-12-26 E. I. Du Pont De Nemours And Company Freeze-dried pharmaceutical compositions of phenylquinoline carboxylic acids
WO1989006227A1 (en) * 1987-12-28 1989-07-13 The Dow Chemical Company Phenoxyphenoxypropionates, intermediates thereof and methods of preparation
US4861783A (en) * 1988-04-26 1989-08-29 E. I. Du Pont De Nemours And Company 4-quinoline carboxylic acid derivatives useful for treating skin and muco-epithelial diseases
US4968702A (en) * 1989-01-17 1990-11-06 American Cyanamid Company Substituted quinolinecarboxylic acids
US4918077A (en) * 1989-01-25 1990-04-17 E. I. Du Pont De Nemours & Co., Inc. 3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents
DE3905339A1 (de) * 1989-02-22 1990-09-06 Basf Ag Chinolin-4-carbonsaeurederivate und deren verwendung
US5393891A (en) * 1993-06-08 1995-02-28 The Du Pont Merck Pharmaceutical Company Immunoassay reagents and methods for detecting brequinar and analogs
IL133009A0 (en) * 1997-05-28 2001-03-19 Aventis Pharm Prod Inc Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases
DE69814012T2 (de) * 1997-12-19 2004-04-01 Eli Lilly And Co., Indianapolis Hypoglykàmische imidazoline derivate
JPWO2004002484A1 (ja) * 2002-06-26 2005-10-27 協和醗酵工業株式会社 ホスホジエステラーゼ阻害剤
US8232310B2 (en) * 2006-12-29 2012-07-31 Georgetown University Targeting of EWS-FLI1 as anti-tumor therapy
JP6130491B2 (ja) 2012-04-12 2017-05-17 ジョージタウン・ユニバーシティGeorgetown University ユーイング肉腫ファミリー腫瘍を治療するための方法及び組成物
RU2016114498A (ru) 2013-10-24 2017-11-29 Джорджтаун Юниверсити Способы и композиции для лечения раковых заболеваний
CN105916522A (zh) 2013-11-22 2016-08-31 建新公司 用于治疗神经变性疾病的新方法
AU2015328121B2 (en) 2014-10-09 2019-11-21 Oncternal Therapeutics, Inc. Indolinone compounds and uses thereof
ES2823190T3 (es) 2016-03-31 2021-05-06 Oncternal Therapeutics Inc Análogos de indolina y usos de los mismos
SG11201811661TA (en) 2016-07-29 2019-01-30 Oncternal Therapeutics Inc Uses of indolinone compounds
US20240018108A1 (en) * 2019-12-26 2024-01-18 Ohio State Innovation Foundation Methods and compositions for inhibition of dihydroorotate dehydrogenase

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE502610A (el) * 1950-04-18
US2888346A (en) * 1955-08-22 1959-05-26 Gen Aniline & Film Corp Ultra-violet absorbing compounds

Also Published As

Publication number Publication date
EP0133244B1 (en) 1990-12-05
AU583793B2 (en) 1989-05-11
HUT35248A (en) 1985-06-28
AU3085284A (en) 1985-01-24
HK142395A (en) 1995-09-15
EP0133244A2 (en) 1985-02-20
FI86987C (fi) 1992-11-10
PT78960A (en) 1984-08-01
NZ208966A (en) 1986-12-05
NO167510B (no) 1991-08-05
SU1452480A3 (ru) 1989-01-15
IE841873L (en) 1985-01-22
IL72471A (en) 1988-11-15
FI86987B (fi) 1992-07-31
DK358784A (da) 1985-01-23
DK358784D0 (da) 1984-07-20
IL72471A0 (en) 1984-11-30
NO167510C (no) 1991-11-13
PT78960B (en) 1986-10-20
HU194832B (en) 1988-03-28
NO842969L (no) 1985-01-23
ES534509A0 (es) 1985-09-01
FI842928A (fi) 1985-01-23
ES8507498A1 (es) 1985-09-01
FI842928A0 (fi) 1984-07-20
EP0133244A3 (en) 1985-12-11
CA1288436C (en) 1991-09-03
DE3483704D1 (de) 1991-01-17
SU1393314A3 (ru) 1988-04-30
IE57627B1 (en) 1993-02-10

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