DK358784A - Phenylquinolincarboxylsyrer, derivater og salte deraf, deres fremstilling og anvendelse i antitumormidler - Google Patents
Phenylquinolincarboxylsyrer, derivater og salte deraf, deres fremstilling og anvendelse i antitumormidler Download PDFInfo
- Publication number
- DK358784A DK358784A DK358784A DK358784A DK358784A DK 358784 A DK358784 A DK 358784A DK 358784 A DK358784 A DK 358784A DK 358784 A DK358784 A DK 358784A DK 358784 A DK358784 A DK 358784A
- Authority
- DK
- Denmark
- Prior art keywords
- phenylquinolincarboxylic
- antitumum
- derivatives
- salts
- acids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
- C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51631983A | 1983-07-22 | 1983-07-22 | |
| US60510484A | 1984-04-30 | 1984-04-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK358784D0 DK358784D0 (da) | 1984-07-20 |
| DK358784A true DK358784A (da) | 1985-01-23 |
Family
ID=27058797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK358784A DK358784A (da) | 1983-07-22 | 1984-07-20 | Phenylquinolincarboxylsyrer, derivater og salte deraf, deres fremstilling og anvendelse i antitumormidler |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0133244B1 (fi) |
| AU (1) | AU583793B2 (fi) |
| CA (1) | CA1288436C (fi) |
| DE (1) | DE3483704D1 (fi) |
| DK (1) | DK358784A (fi) |
| ES (1) | ES534509A0 (fi) |
| FI (1) | FI86987C (fi) |
| GR (1) | GR82234B (fi) |
| HK (1) | HK142395A (fi) |
| HU (1) | HU194832B (fi) |
| IE (1) | IE57627B1 (fi) |
| IL (1) | IL72471A (fi) |
| NO (1) | NO167510C (fi) |
| NZ (1) | NZ208966A (fi) |
| PT (1) | PT78960B (fi) |
| SU (2) | SU1393314A3 (fi) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4889862A (en) * | 1986-08-28 | 1989-12-26 | E. I. Du Pont De Nemours And Company | Freeze-dried pharmaceutical compositions of phenylquinoline carboxylic acids |
| HUT55742A (en) * | 1987-12-28 | 1991-06-28 | Dowelanco | Process for producing (phenoxy-phenoxy)-propionate derivatives and theyr new intermediates |
| US4861783A (en) * | 1988-04-26 | 1989-08-29 | E. I. Du Pont De Nemours And Company | 4-quinoline carboxylic acid derivatives useful for treating skin and muco-epithelial diseases |
| US4968702A (en) * | 1989-01-17 | 1990-11-06 | American Cyanamid Company | Substituted quinolinecarboxylic acids |
| US4918077A (en) * | 1989-01-25 | 1990-04-17 | E. I. Du Pont De Nemours & Co., Inc. | 3-phenyl-5,6-dihydrobenz(c)acridine-7-carboxylic acids and related compounds as cancer chemotherapeutic agents |
| DE3905339A1 (de) * | 1989-02-22 | 1990-09-06 | Basf Ag | Chinolin-4-carbonsaeurederivate und deren verwendung |
| US5393891A (en) * | 1993-06-08 | 1995-02-28 | The Du Pont Merck Pharmaceutical Company | Immunoassay reagents and methods for detecting brequinar and analogs |
| JP2002500675A (ja) * | 1997-05-28 | 2002-01-08 | アヴェンティス ファーマシューティカルズ プロダクツ インコーポレイテッド | 血小板由来成長因子及び／又はｐ５６▲上ｌｃｋ▼チロシンキナーゼを阻害するキノリン及びキノキサリン化合物 |
| ZA9811672B (en) * | 1997-12-19 | 2000-06-19 | Lilly Co Eli | Hypoglycemic imidazoline compounds. |
| CA2493854A1 (en) * | 2002-06-26 | 2004-01-08 | Kyowa Hakko Kogyo Co., Ltd. | Phosphodiesterase inhibitor |
| US8232310B2 (en) * | 2006-12-29 | 2012-07-31 | Georgetown University | Targeting of EWS-FLI1 as anti-tumor therapy |
| IN2014DN09228A (fi) | 2012-04-12 | 2015-07-10 | Univ Georgetown | |
| AU2014340398A1 (en) | 2013-10-24 | 2016-06-09 | Georgetown University | Methods and compositions for treating cancer |
| CN105916522A (zh) | 2013-11-22 | 2016-08-31 | 建新公司 | 用于治疗神经变性疾病的新方法 |
| EA032644B1 (ru) | 2014-10-09 | 2019-06-28 | Онктернал Терапьютикс, Инк. | Производные индолинона и их применение |
| DK3436434T3 (da) | 2016-03-31 | 2020-09-21 | Oncternal Therapeutics Inc | Indolin-analoger og anvendelser deraf |
| SG11201811661TA (en) | 2016-07-29 | 2019-01-30 | Oncternal Therapeutics Inc | Uses of indolinone compounds |
| WO2021134042A1 (en) * | 2019-12-26 | 2021-07-01 | Ohio State Innovation Foundation | Methods and compositions for inhibition of dihydroorotate dehydrogenase |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE502610A (fi) * | 1950-04-18 | |||
| US2888346A (en) * | 1955-08-22 | 1959-05-26 | Gen Aniline & Film Corp | Ultra-violet absorbing compounds |
-
1984
- 1984-07-19 DE DE8484108523T patent/DE3483704D1/de not_active Expired - Lifetime
- 1984-07-19 EP EP84108523A patent/EP0133244B1/en not_active Expired - Lifetime
- 1984-07-19 CA CA000459263A patent/CA1288436C/en not_active Expired - Lifetime
- 1984-07-19 AU AU30852/84A patent/AU583793B2/en not_active Ceased
- 1984-07-20 PT PT78960A patent/PT78960B/pt not_active IP Right Cessation
- 1984-07-20 IE IE1873/84A patent/IE57627B1/en not_active IP Right Cessation
- 1984-07-20 IL IL72471A patent/IL72471A/xx not_active IP Right Cessation
- 1984-07-20 HU HU842824A patent/HU194832B/hu not_active IP Right Cessation
- 1984-07-20 FI FI842928A patent/FI86987C/fi not_active IP Right Cessation
- 1984-07-20 ES ES534509A patent/ES534509A0/es active Granted
- 1984-07-20 NZ NZ208966A patent/NZ208966A/en unknown
- 1984-07-20 DK DK358784A patent/DK358784A/da not_active Application Discontinuation
- 1984-07-20 GR GR75386A patent/GR82234B/el unknown
- 1984-07-20 NO NO842969A patent/NO167510C/no unknown
- 1984-07-20 SU SU843776940A patent/SU1393314A3/ru active
-
1986
- 1986-01-06 SU SU864000869A patent/SU1452480A3/ru active
-
1995
- 1995-09-07 HK HK142395A patent/HK142395A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT78960A (en) | 1984-08-01 |
| DE3483704D1 (de) | 1991-01-17 |
| CA1288436C (en) | 1991-09-03 |
| AU583793B2 (en) | 1989-05-11 |
| EP0133244B1 (en) | 1990-12-05 |
| PT78960B (en) | 1986-10-20 |
| HUT35248A (en) | 1985-06-28 |
| ES8507498A1 (es) | 1985-09-01 |
| NO167510C (no) | 1991-11-13 |
| HU194832B (en) | 1988-03-28 |
| IL72471A0 (en) | 1984-11-30 |
| GR82234B (fi) | 1984-12-13 |
| FI86987B (fi) | 1992-07-31 |
| EP0133244A2 (en) | 1985-02-20 |
| EP0133244A3 (en) | 1985-12-11 |
| FI86987C (fi) | 1992-11-10 |
| NO842969L (no) | 1985-01-23 |
| IL72471A (en) | 1988-11-15 |
| SU1393314A3 (ru) | 1988-04-30 |
| IE841873L (en) | 1985-01-22 |
| NZ208966A (en) | 1986-12-05 |
| AU3085284A (en) | 1985-01-24 |
| HK142395A (en) | 1995-09-15 |
| FI842928A (fi) | 1985-01-23 |
| FI842928A0 (fi) | 1984-07-20 |
| DK358784D0 (da) | 1984-07-20 |
| ES534509A0 (es) | 1985-09-01 |
| NO167510B (no) | 1991-08-05 |
| IE57627B1 (en) | 1993-02-10 |
| SU1452480A3 (ru) | 1989-01-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |