FI80885B - Framstaellning av nya guaninderivat. - Google Patents

Framstaellning av nya guaninderivat.

Info

Publication number
FI80885B
FI80885B FI853171A FI853171A FI80885B FI 80885 B FI80885 B FI 80885B FI 853171 A FI853171 A FI 853171A FI 853171 A FI853171 A FI 853171A FI 80885 B FI80885 B FI 80885B
Authority
FI
Finland
Prior art keywords
guaninderivat
nya
framstaellning
nya guaninderivat
Prior art date
Application number
FI853171A
Other languages
English (en)
Other versions
FI853171A0 (fi
FI853171L (fi
FI80885C (fi
Inventor
Karl Nils-Gunnar Johansson
Bjoern Gunnar Lindborg
Jan-Olof Noren
Original Assignee
Medivir Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE8307051A external-priority patent/SE8307051D0/xx
Priority claimed from SE8307052A external-priority patent/SE8307052D0/xx
Application filed by Medivir Ab filed Critical Medivir Ab
Publication of FI853171A0 publication Critical patent/FI853171A0/fi
Publication of FI853171L publication Critical patent/FI853171L/fi
Publication of FI80885B publication Critical patent/FI80885B/fi
Application granted granted Critical
Publication of FI80885C publication Critical patent/FI80885C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/17—Unsaturated ethers containing halogen
    • C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
    • C07C43/1745—Unsaturated ethers containing halogen containing six-membered aromatic rings having more than one ether bound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1785—Unsaturated ethers containing hydroxy or O-metal groups having more than one ether bound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1787—Unsaturated ethers containing hydroxy or O-metal groups containing six-membered aromatic rings and having unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI853171A 1983-12-20 1985-08-19 Framstaellning av nya guaninderivat. FI80885C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
SE8307052 1983-12-20
SE8307051A SE8307051D0 (sv) 1983-12-20 1983-12-20 Novel derivatives of alkyl guanine novel derivatives of alkyl guanine
SE8307052A SE8307052D0 (sv) 1983-12-20 1983-12-20 Novel derivatives of guanine novel derivatives of guanine
SE8307051 1983-12-20
PCT/SE1984/000426 WO1985002845A1 (en) 1983-12-20 1984-12-13 Novel derivatives of guanine
SE8400426 1984-12-13

Publications (4)

Publication Number Publication Date
FI853171A0 FI853171A0 (fi) 1985-08-19
FI853171L FI853171L (fi) 1985-08-19
FI80885B true FI80885B (fi) 1990-04-30
FI80885C FI80885C (fi) 1990-08-10

Family

ID=26658599

Family Applications (1)

Application Number Title Priority Date Filing Date
FI853171A FI80885C (fi) 1983-12-20 1985-08-19 Framstaellning av nya guaninderivat.

Country Status (20)

Country Link
US (1) US4798833A (fi)
EP (2) EP0165289B1 (fi)
JP (1) JPH0667939B2 (fi)
KR (1) KR910010048B1 (fi)
AU (1) AU586415B2 (fi)
CA (1) CA1285560C (fi)
DE (1) DE3477568D1 (fi)
DK (1) DK159683C (fi)
ES (3) ES8609325A1 (fi)
FI (1) FI80885C (fi)
GB (1) GB2151622B (fi)
GR (1) GR82499B (fi)
HU (1) HU193595B (fi)
IE (1) IE57913B1 (fi)
IL (1) IL73682A (fi)
IS (1) IS1507B (fi)
MY (1) MY102565A (fi)
PH (1) PH21410A (fi)
PT (1) PT79714B (fi)
WO (1) WO1985002845A1 (fi)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5684153A (en) 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
DE3485225D1 (de) * 1983-08-18 1991-12-05 Beecham Group Plc Antivirale guanin-derivate.
CA1288098C (en) * 1984-08-24 1991-08-27 Richard L. Tolman 4-(guanin-9-yl)butanals and their 3-oxa, 3-thia and 2-ene derivatives having antiviral and antitumor activity
SE8406538D0 (sv) * 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
DE3671227D1 (de) * 1985-07-27 1990-06-21 Beecham Group Plc 9-substituierte guaninmonohydrate.
EP0219838A3 (en) * 1985-10-22 1988-04-06 Takeda Chemical Industries, Ltd. Carbocyclic purine nucleosides, their production and use
US5565566A (en) * 1987-04-24 1996-10-15 Discovery Therapeutics, Inc. N6 -substituted 9-methyladenines: a new class of adenosine receptor antagonists
US5066655A (en) * 1987-04-24 1991-11-19 Whitby Research, Inc. N6-substituted 9-methyladenines: a new class of adenosine receptor antagonists
US5175288A (en) * 1987-08-01 1992-12-29 Beecham Group P.L.C. Process for preparing purine derivatives and intermediates thereof
US4935427A (en) * 1987-12-31 1990-06-19 The United States Of America As Represented By The Department Of Health And Human Services Pyrimidine and purine 1,2-butadiene-4-ols as anti-retroviral agents
US5284837A (en) * 1988-05-06 1994-02-08 Medivir Ab Derivatives of purine, process for their preparation and a pharmaceutical preparation
SE8801729D0 (sv) * 1988-05-06 1988-05-06 Astra Ab Purine derivatives for use in therapy
GB8817607D0 (en) * 1988-07-23 1988-09-01 Beecham Group Plc Novel process
GB8822236D0 (en) * 1988-09-21 1988-10-26 Beecham Group Plc Chemical process
CA2009109A1 (en) * 1989-02-02 1990-08-02 John Hannah Antiviral acyclonucleosides and acyclonucleotides
GB8904855D0 (en) * 1989-03-03 1989-04-12 Beecham Group Plc Pharmaceutical treatment
GB8917959D0 (en) * 1989-08-05 1989-09-20 Beecham Group Plc Pharmaceutical formulation
GB8922076D0 (en) * 1989-09-28 1989-11-15 Beecham Group Plc Novel process
GB9001886D0 (en) * 1990-01-26 1990-03-28 Beecham Group Plc Pharmaceutical formulation
US5674869A (en) * 1990-07-07 1997-10-07 Beecham Group Plc Pharmaceutical treatment
ES2132411T3 (es) * 1993-06-23 1999-08-16 Merrell Pharma Inc Derivados nucleosidicos carbo-aciclicos como agentes antivirasicos y antineoplasicos.
US5869493A (en) * 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
PT102030B (pt) * 1996-07-20 1999-04-30 Smithkline Beecham Plc Processo para a apreparacao dos compostos penciclovir ou famciclovir que sao utesi como agentes antivirais
GB9615276D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9615253D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9807114D0 (en) * 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
US20230218644A1 (en) 2020-04-16 2023-07-13 Som Innovation Biotech, S.A. Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4347360A (en) * 1980-09-16 1982-08-31 Ens Bio Logicals Inc. Ring open nucleoside analogues
IL64501A (en) * 1980-12-22 1985-07-31 Astra Laekemedel Ab 9-substituted 4-hydroxybutyl guanine derivatives,their preparation and antiviral use
US4355032B2 (en) * 1981-05-21 1990-10-30 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent
MC1475A1 (fr) * 1981-08-11 1983-06-17 Wellcome Found Procede de preparation de derives de la purine a action anti-virale
NZ201662A (en) * 1981-08-26 1986-07-11 Merck & Co Inc 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation
AU564576B2 (en) * 1981-09-24 1987-08-20 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Purine derivatives
US5250535A (en) * 1982-02-01 1993-10-05 Syntex Inc. Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
SE8203855D0 (sv) * 1982-06-21 1982-06-21 Astra Laekemedel Ab Novel derivatives of guanine i
SE8203856D0 (sv) * 1982-06-21 1982-06-21 Astra Laekemedel Ab Novel derivatives of guanine ii
DE3485225D1 (de) * 1983-08-18 1991-12-05 Beecham Group Plc Antivirale guanin-derivate.
DE3671227D1 (de) * 1985-07-27 1990-06-21 Beecham Group Plc 9-substituierte guaninmonohydrate.

Also Published As

Publication number Publication date
ES538721A0 (es) 1986-09-01
AU586415B2 (en) 1989-07-13
DE3477568D1 (en) 1989-05-11
IL73682A (en) 1991-08-16
ES8800946A1 (es) 1987-12-01
EP0146516A3 (en) 1985-08-14
PH21410A (en) 1987-10-15
ES546916A0 (es) 1987-03-16
CA1285560C (en) 1991-07-02
DK159683B (da) 1990-11-19
AU3787385A (en) 1985-07-12
HU193595B (en) 1987-11-30
EP0146516A2 (en) 1985-06-26
ES8609325A1 (es) 1986-09-01
DK159683C (da) 1991-04-15
GB2151622A (en) 1985-07-24
WO1985002845A1 (en) 1985-07-04
DK362585D0 (da) 1985-08-09
JPS61500730A (ja) 1986-04-17
US4798833A (en) 1989-01-17
MY102565A (en) 1992-07-31
PT79714A (en) 1985-01-01
FI853171A0 (fi) 1985-08-19
IE843261L (en) 1985-06-20
PT79714B (en) 1986-12-30
GB8431910D0 (en) 1985-01-30
IE57913B1 (en) 1993-05-19
IL73682A0 (en) 1985-02-28
ES8704170A1 (es) 1987-03-16
KR910010048B1 (ko) 1991-12-12
ES554546A0 (es) 1987-12-01
FI853171L (fi) 1985-08-19
JPH0667939B2 (ja) 1994-08-31
HUT37619A (en) 1986-01-23
GB2151622B (en) 1988-05-11
FI80885C (fi) 1990-08-10
EP0165289B1 (en) 1989-04-05
IS2966A7 (is) 1985-06-21
DK362585A (da) 1985-08-09
EP0165289A1 (en) 1985-12-27
IS1507B (is) 1992-09-29
GR82499B (en) 1985-04-19
KR850700136A (ko) 1985-10-25

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: MEDIVIR AB