FI82266C
(fi)
*
|
1982-10-19 |
1991-02-11 |
Cetus Corp |
Foerfarande foer framstaellning av il-2 -mutein.
|
US5288852A
(en)
*
|
1984-03-06 |
1994-02-22 |
Dainippon Pharmaceutical Co., Ltd. |
Human tumor necrosis factor polypeptides
|
US5342614A
(en)
*
|
1984-12-21 |
1994-08-30 |
Otsuka Pharmaceutical Co., Ltd. |
Method of treating arthritus or inflammation with IL-1β or derivatives thereof
|
US6107465A
(en)
*
|
1984-12-21 |
2000-08-22 |
Otsuka Pharmaceutical Co., Ltd. |
IL-1β and derivatives thereof and drugs
|
US5516896A
(en)
*
|
1985-02-25 |
1996-05-14 |
Zymogenetics, Inc. |
Biologically active B-chain homodimers
|
US5244806A
(en)
*
|
1985-08-26 |
1993-09-14 |
Eli Lilly And Company |
DNA encoding novel tissue plasminogen activator derivatives having kringles 1 and 2 deleted, vectors and host cells
|
US5859208A
(en)
*
|
1988-07-06 |
1999-01-12 |
Fiddes; John C. |
Human basic fibroblast growth factor analog
|
US5081021A
(en)
*
|
1986-02-04 |
1992-01-14 |
Mizuno Den Ichi |
DNA encoding HTNF variants exhibiting enhanced activity
|
US5008374A
(en)
*
|
1986-03-14 |
1991-04-16 |
Otsuka Pharmaceutical Co., Ltd. |
IL-1α derivatives and drugs
|
US5900476A
(en)
*
|
1986-05-30 |
1999-05-04 |
The Scripps Research Institute |
Therapeutic domains of van Willebrand factor
|
EP0257406B2
(en)
*
|
1986-08-06 |
1998-08-12 |
Ajinomoto Co., Inc. |
Recombinant B-cell differentiation factor
|
US5681934A
(en)
*
|
1986-09-30 |
1997-10-28 |
Board Of Regents, The University Of Texas System |
47-kilodalton antigen of Treponema pallidum
|
US6994988B1
(en)
|
1987-02-12 |
2006-02-07 |
Genetech, Inc. |
Methods and deoxyribonucleic acid for the preparation of tissue factor protein
|
US7049131B1
(en)
*
|
1987-02-12 |
2006-05-23 |
Genentech, Inc. |
Methods and deoxyribonucleic acid for the preparation of tissue factor protein
|
US5852177A
(en)
*
|
1987-02-24 |
1998-12-22 |
Takeda Chemical Industries, Ltd. |
Basic fibroblast growth factor (bFGF) muteins
|
AU1346488A
(en)
*
|
1987-02-26 |
1988-09-26 |
Cetus Corporation |
Arginine-depleted human tumor necrosis factor
|
ZA884012B
(en)
*
|
1987-06-04 |
1989-02-22 |
Zymogenetics Inc |
Tissue plasminogen activator analogs having modified growth factor domains
|
DE68929273T2
(de)
*
|
1988-08-24 |
2001-07-05 |
American Cyanamid Co., Wayne |
Stabilisierung von Somatotropinen durch Modifikation von Cystein-Resten durch orts-spezifische Mutagenese oder chemische Derivatisierung
|
DE3907244A1
(de)
*
|
1989-03-07 |
1990-09-13 |
Knoll Ag |
Erzeugnisse, enthaltend ein lithiumsalz und einen tumor-nekrose-faktor
|
US5621078A
(en)
*
|
1989-03-22 |
1997-04-15 |
Merck & Co., Inc. |
Modified pseudomonas exotoxin PE40
|
AU5355790A
(en)
*
|
1989-04-19 |
1990-11-16 |
Cetus Corporation |
Multifunctional m-csf proteins and genes encoding therefor
|
US6207798B1
(en)
*
|
1989-08-03 |
2001-03-27 |
Merck & Co., Inc. |
Modified PE40 toxin fusion proteins
|
FR2651130B1
(fr)
*
|
1989-08-23 |
1991-12-13 |
Roussel Uclaf |
Sequence d'oligonucleotides anti-sens, anti-arn message du tnf alpha, procede de preparation, application a titre de medicaments et compositions pharmaceutiques.
|
EP0447523A4
(en)
*
|
1989-10-10 |
1991-11-27 |
Amgen Inc. |
Compositions and methods for treating or preventing infections in canine and feline animals
|
US6852313B1
(en)
|
1989-10-16 |
2005-02-08 |
Amgen Inc. |
Method of stimulating growth of melanocyte cells by administering stem cell factor
|
GEP20002145B
(en)
*
|
1989-10-16 |
2000-06-25 |
Amgen Inc Us |
Stem Cell Factor
|
US20040181044A1
(en)
*
|
1989-10-16 |
2004-09-16 |
Zsebo Krisztina M. |
Method of stimulating growth of epithelial cells by administering stem cell factor
|
US7144731B2
(en)
*
|
1989-10-16 |
2006-12-05 |
Amgen Inc. |
SCF antibody compositions and methods of using the same
|
US6552170B1
(en)
*
|
1990-04-06 |
2003-04-22 |
Amgen Inc. |
PEGylation reagents and compounds formed therewith
|
US6566098B1
(en)
*
|
1990-09-14 |
2003-05-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
DNA encoding truncated hepatocyte growth factor variants
|
DE69121227T2
(de)
*
|
1990-09-21 |
1997-02-20 |
Ishihara Sangyo Kaisha |
Polypeptid
|
JPH05255393A
(ja)
*
|
1990-09-21 |
1993-10-05 |
Ishihara Sangyo Kaisha Ltd |
ポリペプチド
|
ES2087207T3
(es)
*
|
1990-11-23 |
1996-07-16 |
American Cyanamid Co |
Factor del crecimiento de fibroblasto quimerico.
|
US6833354B1
(en)
*
|
1990-12-19 |
2004-12-21 |
Kaken Pharmaceutical Co., Ltd. |
Agent for the treatment of bone diseases
|
EP0648268A1
(en)
*
|
1991-03-27 |
1995-04-19 |
The Scripps Research Institute |
Therapeutic fragments of von willebrand factor
|
JP3303211B2
(ja)
*
|
1991-04-26 |
2002-07-15 |
武田薬品工業株式会社 |
bFGFムテインおよびその製造法
|
US5847086A
(en)
*
|
1991-06-20 |
1998-12-08 |
Centeon L.L.C. |
Therapeutic fragments of von Willebrand factor
|
EP0590048B1
(en)
*
|
1991-06-20 |
2004-12-01 |
Aventis Behring L.L.C. |
A process for preparing therapeutic fragments of von willebrand factor
|
ZA924674B
(en)
*
|
1991-07-02 |
1993-04-28 |
Imclone Systems Inc |
Cysteine depleted il-6 mutein
|
US5248604A
(en)
*
|
1991-07-22 |
1993-09-28 |
Bio-Technology General Corp. |
Enzymatically active recombinant human acetylcholinesterase and hosts and vectors for expression thereof
|
FR2686899B1
(fr)
*
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
GB9204439D0
(en)
*
|
1992-02-27 |
1992-04-15 |
Fujisawa Pharmaceutical Co |
A new cephalosporin c acylase
|
US5326695A
(en)
*
|
1992-05-15 |
1994-07-05 |
Ludwig Institute For Cancer Research |
Platelet derived growth factor agonists
|
US5444151A
(en)
*
|
1992-05-15 |
1995-08-22 |
Ludwig Institute For Cancer Research |
Platelet derived growth factor antagonists
|
US5349056A
(en)
*
|
1992-10-09 |
1994-09-20 |
Regeneron Pharmaceuticals |
Modified ciliary neurotrophic factors
|
US5420019A
(en)
*
|
1993-02-02 |
1995-05-30 |
Xoma Corporation |
Stable bactericidal/permeability-increasing protein muteins
|
CN1103815C
(zh)
*
|
1993-11-12 |
2003-03-26 |
吉里德科学公司 |
凝血酶突变体
|
US7060484B1
(en)
|
1993-11-12 |
2006-06-13 |
Gilead Sciences, Inc. |
Polypeptides and coagulation therapy
|
US20030220233A1
(en)
|
1994-01-24 |
2003-11-27 |
Neorx Corporation |
Radiolabeled annexins
|
US5968477A
(en)
*
|
1994-01-24 |
1999-10-19 |
Neorx Corporation |
Radiolabeled annexin conjugates with hexose and a chelator
|
US5545723A
(en)
*
|
1994-03-15 |
1996-08-13 |
Biogen Inc. |
Muteins of IFN-β
|
WO1996011949A2
(en)
*
|
1994-10-13 |
1996-04-25 |
Amgen Inc. |
Analogs of keratinocyte growth factor
|
US6130071A
(en)
*
|
1997-02-05 |
2000-10-10 |
Helsinki University Licensing, Ltd. |
Vascular endothelial growth factor C (VEGF-C) ΔCys156 protein and gene, and uses thereof
|
US6818220B1
(en)
|
1994-11-14 |
2004-11-16 |
Licentia Ltd. |
Vascular endothelial growth factor C (VEGF-C) protein and gene mutants thereof, and uses thereof
|
US6645933B1
(en)
|
1995-08-01 |
2003-11-11 |
Helsinki University Licensing Ltd. Oy |
Receptor ligand VEGF-C
|
IL114615A0
(en)
|
1995-07-16 |
1995-11-27 |
Yeda Res & Dev |
Modulators of the function of fas receptors and other proteins
|
IL117175A
(en)
*
|
1995-02-20 |
2005-11-20 |
Sankyo Co |
Osteoclastogenesis inhibitory factor protein
|
US6361946B1
(en)
|
1997-02-05 |
2002-03-26 |
Licentia Ltd |
Vascular endothelial growth factor C (VEGF-C) protein and gene, mutants thereof, and uses thereof
|
US7423125B2
(en)
|
1995-08-01 |
2008-09-09 |
Vegenics Limited |
Antibodies to VEGF-C
|
US20030202980A1
(en)
*
|
1995-12-29 |
2003-10-30 |
Caplan Michael J. |
Methods and reagents for decreasing clinical reaction to allergy
|
GB9526733D0
(en)
|
1995-12-30 |
1996-02-28 |
Delta Biotechnology Ltd |
Fusion proteins
|
TW555765B
(en)
|
1996-07-09 |
2003-10-01 |
Amgen Inc |
Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
|
US6743422B1
(en)
|
1996-10-15 |
2004-06-01 |
Amgen, Inc. |
Keratinocyte growth factor-2 products
|
US20030144202A1
(en)
*
|
1996-10-15 |
2003-07-31 |
Amgen Inc. |
Uses of keratinocyte growth factor-2
|
DK0942740T3
(da)
|
1996-12-06 |
2003-12-15 |
Amgen Inc |
Kombinationsterapi under anvendelse af et TFN-bindende protein til behandling af TFN-medierede sygdomme
|
DE69740107D1
(de)
|
1996-12-23 |
2011-03-10 |
Immunex Corp |
Rezeptor aktivator von nf-kappa b, rezeptor is mitglied der tnf rezeptor superfamilie
|
US6558671B1
(en)
|
1997-01-30 |
2003-05-06 |
The University Of Virginia Patent Foundation |
Cysteine-depleted peptides recognized by A3-restricted cytotoxic lymphocytes, and uses therefor
|
US7125714B2
(en)
*
|
1997-02-05 |
2006-10-24 |
Licentia Ltd. |
Progenitor cell materials and methods
|
PT911342E
(pt)
*
|
1997-04-15 |
2006-08-31 |
Sankyo Co |
Nova proteina e processo para a produzir
|
SK288559B6
(sk)
|
1997-04-16 |
2018-05-02 |
Amgen, Inc. |
Nukleová kyselina, polypeptid, expresný vektor a hostiteľská bunka; proteín viažuci osteoprotegerín a spôsob jeho prípravy, protilátka a liečivo na prevenciu alebo liečenie chorôb kostí
|
US6316408B1
(en)
*
|
1997-04-16 |
2001-11-13 |
Amgen Inc. |
Methods of use for osetoprotegerin binding protein receptors
|
EP1173191A4
(en)
*
|
1997-05-13 |
2004-12-01 |
Univ California |
NOVEL ANTI-ANGIOGENIC PEPTIDE AGENTS, USE OF THE SAME FOR THERAPY AND DIAGNOSIS
|
US7723473B2
(en)
*
|
1997-06-19 |
2010-05-25 |
St. Louis University |
Peptide antagonists of TGF-beta family members and therapeutic uses thereof
|
WO1999031241A1
(en)
*
|
1997-12-17 |
1999-06-24 |
Immunex Corporation |
Cell surface glycoproteins associated with human b cell lymphomas - ulbp, dna and polypeptides
|
US8101349B2
(en)
|
1997-12-23 |
2012-01-24 |
Novartis Vaccines And Diagnostics, Inc. |
Gene products differentially expressed in cancerous cells and their methods of use II
|
US7879977B2
(en)
|
1998-01-31 |
2011-02-01 |
University Of Arkansas |
Methods and reagents for decreasing clinical reaction to allergy
|
AU743647B2
(en)
|
1998-01-31 |
2002-01-31 |
Mt. Sinai School Of Medicine Of New York University |
Methods and reagents for decreasing allergic reactions
|
US6955807B1
(en)
|
1998-05-15 |
2005-10-18 |
Bayer Pharmaceuticals Corporation |
IL-2 selective agonists and antagonists
|
US6387645B1
(en)
|
1998-07-16 |
2002-05-14 |
Hyseq, Inc. |
Methods and materials relating to novel CD39-like polypeptides
|
US6476211B1
(en)
|
1998-07-16 |
2002-11-05 |
Hyseq, Inc. |
Methods and materials relating to CD39-like polypeptides
|
US6447771B1
(en)
|
1999-03-19 |
2002-09-10 |
Hyseq, Inc. |
Methods and materials relating to novel CD39-like polypeptides
|
IL140931A0
(en)
*
|
1998-07-16 |
2002-02-10 |
Hyseq Inc |
Methods and materials relating to novel cd39-like polypeptides
|
US6979442B1
(en)
|
1998-08-17 |
2005-12-27 |
Pfizer Inc. |
Stabilized protein compositions
|
ATE434440T1
(de)
|
1998-09-03 |
2009-07-15 |
Novartis Vaccines & Diagnostic |
Fgf-2 angiogenische wirksame einheitdosis und verfahren zu ihrer verwendung
|
US6660843B1
(en)
*
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
US6696063B1
(en)
*
|
1998-12-30 |
2004-02-24 |
Applied Research Systems Ars Holding N.V. |
Treatment of HIV-associated dysmorphia/dysmetabolic syndrome (HADDS) with or without lipodystrophy
|
US7625859B1
(en)
|
2000-02-16 |
2009-12-01 |
Oregon Health & Science University |
HER-2 binding antagonists
|
US7393823B1
(en)
|
1999-01-20 |
2008-07-01 |
Oregon Health And Science University |
HER-2 binding antagonists
|
US6350447B1
(en)
|
1999-01-29 |
2002-02-26 |
Hyseq, Inc. |
Methods and compositions relating to CD39-like polypeptides and nucleic acids
|
US6899875B1
(en)
|
1999-01-29 |
2005-05-31 |
Nuvelo, Inc. |
Methods and compositions relating to CD39-like polypeptides and nucleic acids
|
US6780977B1
(en)
|
1999-01-29 |
2004-08-24 |
Nuvelo, Inc. |
Methods and compositions relating to CD39-like polypeptides and nucleic acids
|
US6783959B1
(en)
|
1999-01-29 |
2004-08-31 |
Nuvelo, Inc. |
Methods and compositions relating to CD39-like polypeptides and nucleic acids
|
US6335013B1
(en)
|
1999-03-19 |
2002-01-01 |
Hyseq, Inc. |
Methods and materials relating to CD39-like polypeptides
|
WO2000061755A2
(en)
*
|
1999-04-09 |
2000-10-19 |
Chiron Corporation |
Secreted human proteins
|
US6514729B1
(en)
|
1999-05-12 |
2003-02-04 |
Xencor, Inc. |
Recombinant interferon-beta muteins
|
US6703221B1
(en)
*
|
1999-08-19 |
2004-03-09 |
Chiron Corporation |
Notch receptor ligands and uses thereof
|
US6825333B1
(en)
*
|
1999-08-20 |
2004-11-30 |
Chiron Corporation |
EGFH2 genes and gene products
|
JP2003516360A
(ja)
*
|
1999-12-09 |
2003-05-13 |
カイロン コーポレイション |
中枢神経系およびリンパ系に対するサイトカイン投与方法
|
US20030103978A1
(en)
*
|
2000-02-23 |
2003-06-05 |
Amgen Inc. |
Selective binding agents of osteoprotegerin binding protein
|
US20050063994A1
(en)
*
|
2000-04-06 |
2005-03-24 |
Caplan Michael J. |
Methods and reagents for decreasing clinical reaction to allergy
|
US8246945B2
(en)
*
|
2000-04-06 |
2012-08-21 |
University Of Arkansas |
Methods and reagents for decreasing clinical reaction to allergy
|
US8153414B2
(en)
*
|
2000-04-06 |
2012-04-10 |
Allertein Therapeutics, Llc |
Microbial delivery system
|
EP1276756A4
(en)
*
|
2000-04-12 |
2004-06-09 |
Human Genome Sciences Inc |
ALBUMIN FUSION PROTEINS
|
US6946134B1
(en)
|
2000-04-12 |
2005-09-20 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
EP1278542A2
(en)
*
|
2000-05-05 |
2003-01-29 |
Cytos Biotechnology AG |
Molecular antigen arrays and vaccines
|
US7700359B2
(en)
*
|
2000-06-02 |
2010-04-20 |
Novartis Vaccines And Diagnostics, Inc. |
Gene products differentially expressed in cancerous cells
|
PT1370684E
(pt)
|
2000-06-15 |
2008-09-08 |
Novartis Vaccines & Diagnostic |
Polinucleótidos ligados ao cancro do colon
|
FR2811323B1
(fr)
*
|
2000-07-07 |
2006-10-06 |
Fuma Tech Gmbh |
Materiau hybride, utilisation dudit materiau hybride et procede de sa fabrication
|
AU2001273447A1
(en)
*
|
2000-07-14 |
2002-01-30 |
Chiron Corporation |
Tetraspan protein and uses thereof
|
CA2430379A1
(en)
|
2000-12-07 |
2002-06-13 |
Chiron Corporation |
Endogenous retroviruses up-regulated in prostate cancer
|
AU2002245182A1
(en)
*
|
2000-12-22 |
2002-07-08 |
Mergen Ltd. |
Methods for identifying g-protein coupled receptors associated with diseases
|
US7094409B2
(en)
|
2001-01-19 |
2006-08-22 |
Cytos Biotechnology Ag |
Antigen arrays for treatment of allergic eosinophilic diseases
|
WO2002059337A1
(en)
*
|
2001-01-26 |
2002-08-01 |
Georgetown University School Of Medicine |
Anti-apoptopic gene scc-s2 and diagnostic and therapeutic uses thereof
|
WO2002081639A2
(en)
*
|
2001-04-06 |
2002-10-17 |
Georgetown University |
Gene brcc2 and diagnostic and therapeutic uses thereof
|
WO2002081641A2
(en)
*
|
2001-04-06 |
2002-10-17 |
Georgetown University |
Gene scc-112 and diagnostic and therapeutic uses thereof
|
WO2002081642A2
(en)
|
2001-04-06 |
2002-10-17 |
Georgetown University |
Gene brcc-3 and diagnostic and therapeutic uses thereof
|
WO2002081640A2
(en)
*
|
2001-04-06 |
2002-10-17 |
Georgetown University |
Gene shinc-1 and diagnostic and therapeutic uses thereof
|
US6887462B2
(en)
|
2001-04-09 |
2005-05-03 |
Chiron Corporation |
HSA-free formulations of interferon-beta
|
US7507413B2
(en)
|
2001-04-12 |
2009-03-24 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
US20050054051A1
(en)
*
|
2001-04-12 |
2005-03-10 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
US20050244931A1
(en)
*
|
2001-04-12 |
2005-11-03 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
US20060084794A1
(en)
*
|
2001-04-12 |
2006-04-20 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
ES2344078T3
(es)
|
2001-06-05 |
2010-08-17 |
Curevac Gmbh |
Arnm estabilizado con un contenido de g/c aumentado para la terapia genetica.
|
EP1476180A4
(en)
*
|
2001-08-13 |
2005-04-20 |
Univ Southern California |
INTERLEUKIN-2 MUTANTS WITH REDUCED TOXICITY
|
EP1436385A4
(en)
*
|
2001-09-14 |
2005-12-14 |
Invitrogen Corp |
DNA POLYMERASES AND MUTANTS CORRESPONDING
|
AU2002332041A1
(en)
*
|
2001-10-05 |
2003-04-22 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
US20040166490A1
(en)
*
|
2002-12-17 |
2004-08-26 |
Morris David W. |
Novel therapeutic targets in cancer
|
US20040126762A1
(en)
*
|
2002-12-17 |
2004-07-01 |
Morris David W. |
Novel compositions and methods in cancer
|
US20060040262A1
(en)
*
|
2002-12-27 |
2006-02-23 |
Morris David W |
Novel compositions and methods in cancer
|
US20040180344A1
(en)
*
|
2003-03-14 |
2004-09-16 |
Morris David W. |
Novel therapeutic targets in cancer
|
US20040197778A1
(en)
*
|
2002-12-26 |
2004-10-07 |
Sagres Discovery, Inc. |
Novel compositions and methods in cancer
|
EP1521594B1
(en)
*
|
2001-12-07 |
2013-10-02 |
Novartis Vaccines and Diagnostics, Inc. |
Endogenous retrovirus polypeptides linked to oncogenic transformation
|
US20060275747A1
(en)
*
|
2001-12-07 |
2006-12-07 |
Hardy Stephen F |
Endogenous retrovirus up-regulated in prostate cancer
|
DE10162480A1
(de)
|
2001-12-19 |
2003-08-07 |
Ingmar Hoerr |
Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen
|
ES2545090T3
(es)
|
2001-12-21 |
2015-09-08 |
Human Genome Sciences, Inc. |
Proteínas de fusión de albúmina y GCSF
|
IL147414A0
(en)
*
|
2001-12-31 |
2002-08-14 |
Yeda Res & Dev |
Ifnar2 mutants, their production and use
|
US20040023267A1
(en)
*
|
2002-03-21 |
2004-02-05 |
Morris David W. |
Novel compositions and methods in cancer
|
WO2003086289A2
(en)
*
|
2002-04-05 |
2003-10-23 |
Amgen Inc. |
Human anti-opgl neutralizing antibodies as selective opgl pathway inhibitors
|
US7138512B2
(en)
*
|
2002-04-10 |
2006-11-21 |
Georgetown University |
Gene SHINC-2 and diagnostic and therapeutic uses thereof
|
US7585840B2
(en)
|
2002-04-10 |
2009-09-08 |
Merck Serono S.A. |
Use of osteoprotegerin for the treatment and/or prevention of fibrotic disease
|
WO2003084560A2
(en)
*
|
2002-04-10 |
2003-10-16 |
Applied Research Systems Ars Holding N.V. |
Use of osteoprotegerin for the prevention and/or treatment of fibrosis/sclerosis
|
US7244565B2
(en)
*
|
2002-04-10 |
2007-07-17 |
Georgetown University |
Gene shinc-3 and diagnostic and therapeutic uses thereof
|
US20030228317A1
(en)
*
|
2002-05-22 |
2003-12-11 |
Prafulla Gokhale |
Gene BRCC-1 and diagnostic and therapeutic uses thereof
|
TWI334785B
(en)
*
|
2002-06-03 |
2010-12-21 |
Serono Lab |
Use of recombinant ifn-β1a and pharmaceutical composition comprising recombinant ifn-β1a for the treatment of hcv infection in patients of asian race
|
AU2003276679A1
(en)
*
|
2002-06-13 |
2003-12-31 |
Chiron Corporation |
Vectors for expression of hml-2 polypeptides
|
AU2003248845A1
(en)
*
|
2002-07-12 |
2004-02-02 |
The Regents Of The University Of California |
Steroidogenic factor-1 protein variants and methods of making same
|
KR101070078B1
(ko)
*
|
2002-07-19 |
2011-10-04 |
노파르티스 파르마 아게 |
아밀로이드 베타1-6 항원 어레이를 포함하는 백신 조성물
|
US20040175359A1
(en)
*
|
2002-11-12 |
2004-09-09 |
Desjarlais John Rudolph |
Novel proteins with antiviral, antineoplastic, and/or immunomodulatory activity
|
EP1594530A4
(en)
|
2003-01-22 |
2006-10-11 |
Human Genome Sciences Inc |
HYBRID PROTEINS OF ALBUMIN
|
US20070218071A1
(en)
*
|
2003-09-15 |
2007-09-20 |
Morris David W |
Novel therapeutic targets in cancer
|
US7767387B2
(en)
*
|
2003-06-13 |
2010-08-03 |
Sagres Discovery, Inc. |
Therapeutic targets in cancer
|
US20040170982A1
(en)
|
2003-02-14 |
2004-09-02 |
Morris David W. |
Novel therapeutic targets in cancer
|
US7537767B2
(en)
*
|
2003-03-26 |
2009-05-26 |
Cytis Biotechnology Ag |
Melan-A- carrier conjugates
|
CN100560719C
(zh)
*
|
2003-03-26 |
2009-11-18 |
赛托斯生物技术公司 |
Melan-a肽类似物-病毒样颗粒偶联物
|
US20060210588A1
(en)
*
|
2003-03-26 |
2006-09-21 |
Cytos Biotechnology Ag |
Hiv-peptide-carrier-conjugates
|
US8252588B2
(en)
|
2003-04-08 |
2012-08-28 |
Yeda Research And Development Co. Ltd. |
Stem cells having increased sensitivity to SDF-1 and methods of generating and using same
|
FR2853551B1
(fr)
|
2003-04-09 |
2006-08-04 |
Lab Francais Du Fractionnement |
Formulation stabilisante pour compositions d'immunoglobulines g sous forme liquide et sous forme lyophilisee
|
TWI272948B
(en)
|
2003-05-01 |
2007-02-11 |
Ares Trading Sa |
HSA-free stabilized interferon liquid formulations
|
US20070281896A1
(en)
*
|
2003-09-30 |
2007-12-06 |
Morris David W |
Novel compositions and methods in cancer
|
IL158287A0
(en)
|
2003-10-07 |
2004-05-12 |
Yeda Res & Dev |
Antibodies to nik, their preparation and use
|
IL158868A0
(en)
*
|
2003-11-13 |
2004-05-12 |
Yeda Res & Dev |
Methods of generating and using stem cells enriched with immature primitive progenitor
|
DE102004008168B4
(de)
*
|
2004-02-19 |
2015-12-10 |
Voxeljet Ag |
Verfahren und Vorrichtung zum Auftragen von Fluiden und Verwendung der Vorrichtung
|
EP1734988A4
(en)
*
|
2004-03-01 |
2009-08-05 |
Enzon Pharmaceuticals Inc |
INTERFERON BETA-polymer
|
IL161673A0
(en)
|
2004-04-29 |
2004-09-27 |
Applied Research Systems |
Compositions and methods for therapy of chemotherapy-induced neuropathy
|
KR20070012464A
(ko)
*
|
2004-05-17 |
2007-01-25 |
아레스 트레이딩 에스.아. |
하이드로겔 인터페론 제제
|
CN1993139B
(zh)
|
2004-06-01 |
2011-02-16 |
阿雷斯贸易股份有限公司 |
稳定的干扰素液体制剂
|
CN1993138B
(zh)
|
2004-06-01 |
2010-12-15 |
阿雷斯贸易股份有限公司 |
稳定蛋白质的方法
|
US20060024677A1
(en)
|
2004-07-20 |
2006-02-02 |
Morris David W |
Novel therapeutic targets in cancer
|
DE102004042546A1
(de)
|
2004-09-02 |
2006-03-09 |
Curevac Gmbh |
Kombinationstherapie zur Immunstimulation
|
AU2005294347A1
(en)
*
|
2004-10-05 |
2006-04-20 |
Oregon Health And Science University |
Compositions and methods for treating disease
|
US20100303760A9
(en)
|
2004-10-27 |
2010-12-02 |
Laboratoires Serono Sa |
Treatment and/or prevention of cancer and/or arthritis
|
GB0424563D0
(en)
*
|
2004-11-05 |
2004-12-08 |
Novartis Ag |
Organic compounds
|
EP1809662B1
(en)
*
|
2004-11-10 |
2008-11-26 |
Novartis Vaccines and Diagnostics, Inc. |
Deamidated interferon-beta
|
TW200633718A
(en)
*
|
2004-12-16 |
2006-10-01 |
Applied Research Systems |
Treatment of hepatitis c in the asian population
|
AU2006235258A1
(en)
|
2005-04-07 |
2006-10-19 |
Novartis Vaccines And Diagnostics Inc. |
Cancer-related genes
|
CA2604885A1
(en)
|
2005-04-07 |
2006-10-19 |
Guoying Yu |
Cacna1e in cancer diagnosis, detection and treatment
|
US20060242012A1
(en)
*
|
2005-04-22 |
2006-10-26 |
Sumit Agarwal |
Determining or scoring properties to solicit to join ad network using advertiser or aggregated advertiser interest
|
KR101451117B1
(ko)
|
2005-05-18 |
2014-10-16 |
바이오팩투라 인코퍼레이티드 |
형질감염된 세포의 대사적 선별을 위한 조성물 및 방법
|
WO2006122972A1
(en)
*
|
2005-05-19 |
2006-11-23 |
Bayer Schering Pharma Aktiengesellschaft |
Interferon-beta gene therapy using an improved, regulated expression system
|
US20070179113A1
(en)
*
|
2005-05-19 |
2007-08-02 |
Schering Aktiengesellachaft |
GM-CSF gene therapy for Crohn's disease using an improved regulated expression system
|
US20080076729A1
(en)
*
|
2005-05-19 |
2008-03-27 |
Schering Aktiengesellachaft |
Interferon-beta gene therapy using an improved, regulated expression system
|
CN101238214A
(zh)
*
|
2005-05-19 |
2008-08-06 |
拜尔先灵制药股份公司 |
使用改进的调节表达系统治疗疾病
|
DK2267024T3
(da)
|
2005-06-03 |
2012-06-25 |
Ares Trading Sa |
Fremstilling af rekombinant II-18 bindingsprotein
|
PL1891088T3
(pl)
*
|
2005-06-10 |
2012-03-30 |
Ares Trading Sa |
Sposób oczyszczania białka wiążącego IL-18
|
US20090111748A1
(en)
*
|
2005-07-21 |
2009-04-30 |
Ellerby Lisa M |
Fibroblast growth factor-2 promotes neurogenesis and neuroprotection and prolongs survival in huntington's disease
|
US20070026463A1
(en)
*
|
2005-07-28 |
2007-02-01 |
Wyeth |
Compositions and methods of mutant Nogo-66 domain proteins
|
MX2008001396A
(es)
*
|
2005-07-29 |
2008-04-16 |
Novartis Ag |
Metodo y sistema para plegado in vitro de proteinas.
|
WO2007022799A1
(en)
|
2005-08-26 |
2007-03-01 |
Ares Trading S.A. |
Process for the preparation of glycosylated interferon beta
|
EP1760092A1
(en)
|
2005-08-26 |
2007-03-07 |
Applied Research Systems ARS Holding N.V. |
System for screening cells for high expression of a protein of interest
|
CA2616479A1
(en)
*
|
2005-09-01 |
2007-03-08 |
Ares Trading S.A. |
Treatment of optic neuritis
|
SI1767545T1
(sl)
|
2005-09-22 |
2010-03-31 |
Biocompatibles Uk Ltd |
GLP Glukagonu podobni peptidi fuzijski polipeptidi s povečano rezistenco na peptidazo
|
MX2008014971A
(es)
|
2006-05-24 |
2008-12-05 |
Serono Lab |
Regimen de cladribine para tratar esclerosis multiple.
|
AU2007264672B2
(en)
|
2006-06-28 |
2013-03-14 |
Hadasit Medical Research Services & Development Ltd |
Caspase-8 and inflammation, infection and wound healing
|
US9131648B2
(en)
*
|
2006-07-07 |
2015-09-15 |
Washington State University |
Genes encoding chavicol/eugenol synthase from the creosote bush Larrea tridentata
|
WO2008031051A2
(en)
*
|
2006-09-08 |
2008-03-13 |
United Therapeutics Corporation |
Clinical diagnosis of hepatic fibrosis using a novel panel of human serum protein biomarkers
|
CN101743018A
(zh)
*
|
2006-12-19 |
2010-06-16 |
梅里麦克药品公司 |
甲胎蛋白和免疫调谐剂的共同施用以治疗多发性硬化
|
WO2008125222A2
(en)
*
|
2007-04-11 |
2008-10-23 |
Bayer Schering Pharma Aktiengesellschaft |
New modulation molecules for an improved regulated expression system
|
NZ580686A
(en)
*
|
2007-05-02 |
2012-11-30 |
Ambrx Inc |
Modified interferon beta polypeptides and their uses
|
US8946201B2
(en)
*
|
2007-08-27 |
2015-02-03 |
Saint Louis University |
Methods for inhibiting TGF-β
|
EP2207890A4
(en)
*
|
2007-10-05 |
2010-12-15 |
Barofold Inc |
HIGH PRESSURE PROCESSING OF AGGREGATED INTERFERONS
|
EA201070773A1
(ru)
*
|
2007-12-20 |
2010-12-30 |
Мерк Сероно С. А. |
Составы пэг-интерферона-бета
|
IL189408A0
(en)
|
2008-02-10 |
2009-02-11 |
Yeda Res & Dev |
Siva3, its preparation and pharmaceutical compositions containing it
|
CN102016046A
(zh)
|
2008-03-04 |
2011-04-13 |
华盛顿州立大学 |
用于区别性调节膜脂和种子油中脂肪酸不饱和性的组合物和方法
|
EA022201B1
(ru)
|
2008-04-11 |
2015-11-30 |
Мерримак Фармасьютикалз, Инк. |
Агент, способный связываться с опухолевой клеткой, содержащий линкер на основе hsa, и его применение
|
US9005599B2
(en)
|
2008-04-21 |
2015-04-14 |
Tissue Regeneration Therapeutics Inc. |
Genetically modified human umbilical cord perivascular cells for prophylaxis against or treatment of biological or chemical agents
|
EP2341913B1
(en)
*
|
2008-09-16 |
2014-11-19 |
Saint Louis University |
Method of enhancing tgf-beta signalling
|
WO2010059315A1
(en)
|
2008-11-18 |
2010-05-27 |
Merrimack Pharmaceuticals, Inc. |
Human serum albumin linkers and conjugates thereof
|
US9074005B2
(en)
*
|
2009-01-02 |
2015-07-07 |
Washington State University |
Compositions and methods for modulating plant disease resistance and immunity
|
CN201397956Y
(zh)
*
|
2009-03-23 |
2010-02-03 |
富士康(昆山)电脑接插件有限公司 |
电连接器组件
|
WO2010133967A1
(en)
*
|
2009-05-14 |
2010-11-25 |
University Of Oxford |
Clinical diagnosis of hepatic fibrosis using a novel panel of low abundant human plasma protein biomarkers
|
BRPI1012951A2
(pt)
*
|
2009-06-09 |
2016-07-26 |
Defyrus Inc |
"administração de interferon para profilaxia ou tratamento de infecção por patôgeno"
|
US20110016548A1
(en)
*
|
2009-07-16 |
2011-01-20 |
University Of Southern California |
Control of endogenous dnmt1 gene expression by exogenous binary regulatory systems
|
CU23734A1
(es)
|
2009-11-27 |
2011-11-15 |
Centro Inmunologia Molecular |
Polipéptidos inmunomoduladores derivados de la il-2 con actividad antagonista de esta citocina útiles en la terapia del cáncer y enfermedades infecciosas crónicas
|
WO2012019168A2
(en)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
CA2821992A1
(en)
|
2010-10-01 |
2012-04-05 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
CU23923B1
(es)
|
2010-11-12 |
2013-07-31 |
Ct De Inmunología Molecular |
Polipéptidos derivados de la il-2 con actividad agonista
|
CA2831613A1
(en)
|
2011-03-31 |
2012-10-04 |
Moderna Therapeutics, Inc. |
Delivery and formulation of engineered nucleic acids
|
WO2012130471A1
(en)
|
2011-04-01 |
2012-10-04 |
Universität Stuttgart |
Recombinant tnf ligand family member polypeptides with antibody binding domain and uses thereof
|
WO2012159945A1
(en)
|
2011-05-20 |
2012-11-29 |
Ares Trading S.A. |
Ifn-beta compositions, preparation methods and uses thereof
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
ES2911677T3
(es)
|
2011-10-03 |
2022-05-20 |
Modernatx Inc |
Nucleósidos, nucleótidos y ácidos nucleicos modificados, y sus usos
|
DE12858350T1
(de)
|
2011-12-16 |
2021-10-07 |
Modernatx, Inc. |
Modifizierte mrna zusammensetzungen
|
JP6280031B2
(ja)
|
2012-03-29 |
2018-02-14 |
中外製薬株式会社 |
抗lamp5抗体およびその利用
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
US10501512B2
(en)
|
2012-04-02 |
2019-12-10 |
Modernatx, Inc. |
Modified polynucleotides
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
EP3501550A1
(en)
|
2012-04-02 |
2019-06-26 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins associated with human disease
|
WO2014036520A1
(en)
|
2012-08-30 |
2014-03-06 |
Merrimack Pharmaceuticals, Inc. |
Combination therapies comprising anti-erbb3 agents
|
US20140161767A1
(en)
*
|
2012-11-15 |
2014-06-12 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Follicle-stimulating hormone (fsh)/lytic domain fusion constructs and methods of making and using same
|
US9597380B2
(en)
|
2012-11-26 |
2017-03-21 |
Modernatx, Inc. |
Terminally modified RNA
|
DK2953634T3
(da)
|
2013-02-07 |
2021-08-30 |
Massachusetts Gen Hospital |
Fremgangsmåder til udvidelse eller udtømning af regulerende t-celler
|
US10077439B2
(en)
|
2013-03-15 |
2018-09-18 |
Modernatx, Inc. |
Removal of DNA fragments in mRNA production process
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
EP3052521A1
(en)
|
2013-10-03 |
2016-08-10 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding low density lipoprotein receptor
|
ES2806575T3
(es)
|
2013-11-01 |
2021-02-18 |
Curevac Ag |
ARN modificado con propiedades inmunoestimuladoras disminuidas
|
CA2963602A1
(en)
|
2014-10-09 |
2016-04-14 |
Dana-Farber Cancer Institute, Inc. |
Multiple-variable il-2 dose regimen for treating immune disorders
|
CN108929383B
(zh)
*
|
2017-05-26 |
2021-10-15 |
阿思科力(苏州)生物科技有限公司 |
重组Slit2D2(C386S)-HSA融合蛋白及其在预防和/或治疗肺部炎症中的应用
|
WO2023122716A1
(en)
|
2021-12-22 |
2023-06-29 |
Vanderbilt University |
Next generation transpososomes
|