DK2953634T3 - Fremgangsmåder til udvidelse eller udtømning af regulerende t-celler - Google Patents
Fremgangsmåder til udvidelse eller udtømning af regulerende t-celler Download PDFInfo
- Publication number
- DK2953634T3 DK2953634T3 DK14748807.6T DK14748807T DK2953634T3 DK 2953634 T3 DK2953634 T3 DK 2953634T3 DK 14748807 T DK14748807 T DK 14748807T DK 2953634 T3 DK2953634 T3 DK 2953634T3
- Authority
- DK
- Denmark
- Prior art keywords
- expanding
- cells
- methods
- depleting regulatory
- depleting
- Prior art date
Links
- 230000000779 depleting effect Effects 0.000 title 1
- 210000003289 regulatory T cell Anatomy 0.000 title 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361762136P | 2013-02-07 | 2013-02-07 | |
US201361763217P | 2013-02-11 | 2013-02-11 | |
PCT/US2014/015101 WO2014124134A1 (en) | 2013-02-07 | 2014-02-06 | Methods for expansion or depletion of t-regulatory cells |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2953634T3 true DK2953634T3 (da) | 2021-08-30 |
Family
ID=51300130
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK14748807.6T DK2953634T3 (da) | 2013-02-07 | 2014-02-06 | Fremgangsmåder til udvidelse eller udtømning af regulerende t-celler |
Country Status (9)
Country | Link |
---|---|
US (3) | US9821010B2 (da) |
EP (2) | EP3936137A1 (da) |
JP (4) | JP6367836B2 (da) |
DK (1) | DK2953634T3 (da) |
ES (1) | ES2885423T3 (da) |
HR (1) | HRP20211353T1 (da) |
PL (1) | PL2953634T3 (da) |
PT (1) | PT2953634T (da) |
WO (1) | WO2014124134A1 (da) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
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US6031552A (en) * | 1994-11-18 | 2000-02-29 | Heidelberger Druckmaschinen Ag | Printing device with patterned recording surface |
DK2953634T3 (da) | 2013-02-07 | 2021-08-30 | Massachusetts Gen Hospital | Fremgangsmåder til udvidelse eller udtømning af regulerende t-celler |
AU2016226414B2 (en) * | 2015-03-02 | 2021-09-09 | 180 Therapeutics Lp | Method of treating a localized fibrotic disorder using an IL-33 antagonist |
EP3283619B1 (en) | 2015-04-17 | 2023-04-05 | Novartis AG | Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells |
US10906982B2 (en) * | 2015-05-15 | 2021-02-02 | The General Hospital Corporation | Antagonistic anti-tumor necrosis factor receptor 2 antibodies |
EP3325504A1 (en) | 2015-07-21 | 2018-05-30 | Novartis AG | Methods for improving the efficacy and expansion of immune cells |
US20190135929A1 (en) * | 2015-08-28 | 2019-05-09 | The General Hospital Corporation | Agonistic anti-tumor necrosis factor receptor 2 antibodies |
EP3355914B1 (en) | 2015-09-29 | 2024-03-06 | The General Hospital Corporation | A composition comprising bcg for reducing cholesterol. |
AU2016344745A1 (en) * | 2015-10-28 | 2018-05-17 | Life Technologies As | Selective expansion of different subpopulations of T cells by the alteration of cell surfacing signals and signal ratio |
EP3374399A1 (en) * | 2015-11-11 | 2018-09-19 | Opi Vi- IP Holdco LLC | Composition and methods for anti-tnfr2 antibodies |
TW201726744A (zh) * | 2016-01-11 | 2017-08-01 | 奧托德里克有限公司 | 用於檢測奧美沙坦(olmesartan)及改善治療高血壓之遵從性的組成物、裝置及方法 |
KR102410778B1 (ko) * | 2016-05-13 | 2022-06-21 | 더 제너럴 하스피탈 코포레이션 | 길항성 항-종양 괴사 인자 수용체 슈퍼패밀리 항체 |
ES2941972T3 (es) * | 2016-06-22 | 2023-05-29 | Univ Paris Val De Marne | Prevención o tratamiento de la recaída de neoplasias malignas hematológicas mediante un antagonista de TNFR2 |
WO2018092907A1 (ja) * | 2016-11-21 | 2018-05-24 | 国立研究開発法人医薬基盤・健康・栄養研究所 | エピトープ均質化抗体パネル、ならびにその作製方法および利用 |
CA3056406A1 (en) | 2017-03-15 | 2018-09-20 | Orca Biosystems Inc. | Compositions and methods for hematopoietic stem cell transplants |
US11851659B2 (en) | 2017-03-22 | 2023-12-26 | Novartis Ag | Compositions and methods for immunooncology |
CA3059472A1 (en) | 2017-05-19 | 2018-11-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Human monoclonal antibody targeting tnfr2 for cancer immunotherapy |
JP7271539B2 (ja) * | 2017-11-14 | 2023-05-11 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | リンホトキシンアルファ遺伝子について遺伝的に改変された調節性t細胞及びその使用 |
JP7387603B2 (ja) * | 2017-11-29 | 2023-11-28 | フィジーン、エルエルシー | 活性化のための線維芽細胞と免疫細胞との相互作用及びそれらの使用 |
EP3853252A1 (en) * | 2018-09-18 | 2021-07-28 | Merrimack Pharmaceuticals, Inc. | Anti-tnfr2 antibodies and uses thereof |
US20220002426A1 (en) | 2018-11-01 | 2022-01-06 | Bioinvent International Ab | Novel agonistic anti tnfr2 antibody molecules |
EP3873936A1 (en) * | 2018-11-01 | 2021-09-08 | BioInvent International AB | Novel antagonistic anti tnfr2 antibody molecules |
CN109609616B (zh) * | 2018-11-05 | 2021-12-07 | 复旦大学附属华山医院 | Hla-a*02:01和hla-c*01:02在丹参酮所致药疹中的用途 |
US20220002423A1 (en) * | 2018-11-15 | 2022-01-06 | The General Hospital Corporation | Agonistic tumor necrosis factor receptor superfamily polypeptides |
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US20200368282A1 (en) | 2020-11-26 |
JP7257374B2 (ja) | 2023-04-13 |
US11844814B2 (en) | 2023-12-19 |
WO2014124134A1 (en) | 2014-08-14 |
PL2953634T3 (pl) | 2021-11-22 |
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