DE69121227T2 - Polypeptid - Google Patents

Polypeptid

Info

Publication number
DE69121227T2
DE69121227T2 DE69121227T DE69121227T DE69121227T2 DE 69121227 T2 DE69121227 T2 DE 69121227T2 DE 69121227 T DE69121227 T DE 69121227T DE 69121227 T DE69121227 T DE 69121227T DE 69121227 T2 DE69121227 T2 DE 69121227T2
Authority
DE
Germany
Prior art keywords
polypeptide
amino acid
acid sequence
mutein
asp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69121227T
Other languages
English (en)
Other versions
DE69121227D1 (de
Inventor
Nobutoshi Yamada
Masanari Kato
Keizo Miyata
Yoshiyuki Aoyama
Hiroshi Shikama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ishihara Sangyo Kaisha Ltd
Original Assignee
Ishihara Sangyo Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3240131A external-priority patent/JPH04368398A/ja
Application filed by Ishihara Sangyo Kaisha Ltd filed Critical Ishihara Sangyo Kaisha Ltd
Application granted granted Critical
Publication of DE69121227D1 publication Critical patent/DE69121227D1/de
Publication of DE69121227T2 publication Critical patent/DE69121227T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69121227T 1990-09-21 1991-09-20 Polypeptid Expired - Fee Related DE69121227T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP25004690 1990-09-21
JP3240131A JPH04368398A (ja) 1991-06-17 1991-06-17 ポリペプチド

Publications (2)

Publication Number Publication Date
DE69121227D1 DE69121227D1 (de) 1996-09-12
DE69121227T2 true DE69121227T2 (de) 1997-02-20

Family

ID=26534592

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69121227T Expired - Fee Related DE69121227T2 (de) 1990-09-21 1991-09-20 Polypeptid

Country Status (3)

Country Link
EP (1) EP0477791B1 (de)
AT (1) ATE141093T1 (de)
DE (1) DE69121227T2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06263650A (ja) * 1991-12-02 1994-09-20 Chiba Seifun Kk Ｌｐｓを含む抗腫瘍剤及び動物用抗腫瘍剤
US5891679A (en) * 1993-02-03 1999-04-06 N.V. Innogenetics S.A. TNF-alpha muteins and a process for preparing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4959314A (en) * 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
WO1988006625A2 (en) * 1987-02-26 1988-09-07 Cetus Corporation Arginine-depleted human tumor necrosis factor

Also Published As

Publication number Publication date
EP0477791B1 (de) 1996-08-07
EP0477791A2 (de) 1992-04-01
ATE141093T1 (de) 1996-08-15
EP0477791A3 (en) 1993-05-05
DE69121227D1 (de) 1996-09-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee