AU1346488A - Arginine-depleted human tumor necrosis factor - Google Patents

Arginine-depleted human tumor necrosis factor

Info

Publication number
AU1346488A
AU1346488A AU13464/88A AU1346488A AU1346488A AU 1346488 A AU1346488 A AU 1346488A AU 13464/88 A AU13464/88 A AU 13464/88A AU 1346488 A AU1346488 A AU 1346488A AU 1346488 A AU1346488 A AU 1346488A
Authority
AU
Australia
Prior art keywords
arginine
necrosis factor
tumor necrosis
human tumor
depleted human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU13464/88A
Inventor
Leo S. Lin
David F. Mark
James W. Thomson
Ralph Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of AU1346488A publication Critical patent/AU1346488A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU13464/88A 1987-02-26 1988-01-25 Arginine-depleted human tumor necrosis factor Abandoned AU1346488A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1922187A 1987-02-26 1987-02-26
US019221 1987-02-26

Publications (1)

Publication Number Publication Date
AU1346488A true AU1346488A (en) 1988-09-26

Family

ID=21792071

Family Applications (1)

Application Number Title Priority Date Filing Date
AU13464/88A Abandoned AU1346488A (en) 1987-02-26 1988-01-25 Arginine-depleted human tumor necrosis factor

Country Status (2)

Country Link
AU (1) AU1346488A (en)
WO (1) WO1988006625A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU655948B2 (en) * 1990-11-21 1995-01-19 F. Hoffmann-La Roche Ag TNF-muteins
AU661652B2 (en) * 1989-10-24 1995-08-03 Chiron Corporation Infective protein delivery system

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3843534A1 (en) * 1988-12-23 1990-07-12 Basf Ag NEW TNF POLYPEPTIDES
FR2651130B1 (en) * 1989-08-23 1991-12-13 Roussel Uclaf SEQUENCE OF ANTI-SENSE OLIGONUCLEOTIDES, ANTI-RNA MESSAGE OF TNF ALPHA, METHOD OF PREPARATION, APPLICATION AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS.
EP0477791B1 (en) * 1990-09-21 1996-08-07 Ishihara Sangyo Kaisha, Ltd. Polypeptide
JPH05255393A (en) * 1990-09-21 1993-10-05 Ishihara Sangyo Kaisha Ltd Polypeptide
KR970005042B1 (en) * 1993-02-09 1997-04-11 한일합성섬유공업 주식회사 Tumor necrosis factor-alpha muteine
CA2119089A1 (en) * 1993-03-29 1994-09-30 David Banner Tumor necrosis factor muteins
IL120979A0 (en) * 1997-06-02 1997-11-20 Interpharm Lab Ltd Glycosylated TNF
GB0328261D0 (en) 2003-12-05 2004-01-07 Univ Groningen Improved cytokine design
DK2953634T3 (en) 2013-02-07 2021-08-30 Massachusetts Gen Hospital Methods for expanding or depleting regulatory t cells
EP3538547B1 (en) 2016-11-09 2021-07-07 Philogen S.p.A. Immunoconjugates comprising il-2, anti-fibronectin antibody and mutant tnf-alpha

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3582183D1 (en) * 1984-03-06 1991-04-25 Dainippon Pharmaceutical Co DNS ENCODING THE HUMAN TUMORNIC CROSIS FACTOR AND THE HUMAN TUMORNIC CRISIS FACTOR POLYPEPTIDE.
GR851626B (en) * 1984-07-05 1985-11-26 Genentech Inc
AU589919B2 (en) * 1984-10-15 1989-10-26 Cetus Corp Human tumor necrosis factor
US4959314A (en) * 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
US5081021A (en) * 1986-02-04 1992-01-14 Mizuno Den Ichi DNA encoding HTNF variants exhibiting enhanced activity

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU661652B2 (en) * 1989-10-24 1995-08-03 Chiron Corporation Infective protein delivery system
AU655948B2 (en) * 1990-11-21 1995-01-19 F. Hoffmann-La Roche Ag TNF-muteins

Also Published As

Publication number Publication date
WO1988006625A3 (en) 1988-10-20
WO1988006625A2 (en) 1988-09-07

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