FI81104C - Foerfarande foer framstaellning av antibiotiskt aktivt kristallint 7-/d- -amino- - (3-klor-4-hydroxifenyl)acetamido/-3-metyl-3-cefem-4-karboxylsyramonohydrat. - Google Patents
Foerfarande foer framstaellning av antibiotiskt aktivt kristallint 7-/d- -amino- - (3-klor-4-hydroxifenyl)acetamido/-3-metyl-3-cefem-4-karboxylsyramonohydrat. Download PDFInfo
- Publication number
- FI81104C FI81104C FI844756A FI844756A FI81104C FI 81104 C FI81104 C FI 81104C FI 844756 A FI844756 A FI 844756A FI 844756 A FI844756 A FI 844756A FI 81104 C FI81104 C FI 81104C
- Authority
- FI
- Finland
- Prior art keywords
- acid
- acetonitrile
- amino
- chloro
- monohydrate
- Prior art date
Links
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- 238000004590 computer program Methods 0.000 description 1
- 239000002178 crystalline material Substances 0.000 description 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 1
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- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
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- FZHAPNGMFPVSLP-UHFFFAOYSA-N silanamine Chemical class [SiH3]N FZHAPNGMFPVSLP-UHFFFAOYSA-N 0.000 description 1
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- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 description 1
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- 239000000454 talc Substances 0.000 description 1
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- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8319463 | 1983-12-06 | ||
| FR8319463A FR2555989B1 (fr) | 1983-12-06 | 1983-12-06 | Monohydrate de chlorocephadroxyle |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI844756A0 FI844756A0 (fi) | 1984-12-03 |
| FI844756L FI844756L (fi) | 1985-06-07 |
| FI81104B FI81104B (fi) | 1990-05-31 |
| FI81104C true FI81104C (fi) | 1990-09-10 |
Family
ID=9294877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI844756A FI81104C (fi) | 1983-12-06 | 1984-12-03 | Foerfarande foer framstaellning av antibiotiskt aktivt kristallint 7-/d- -amino- - (3-klor-4-hydroxifenyl)acetamido/-3-metyl-3-cefem-4-karboxylsyramonohydrat. |
Country Status (25)
| Country | Link |
|---|---|
| JP (1) | JPH0794461B2 (en, 2012) |
| KR (1) | KR920001769B1 (en, 2012) |
| AT (1) | AT386411B (en, 2012) |
| AU (1) | AU567780B2 (en, 2012) |
| BE (1) | BE901218A (en, 2012) |
| CA (1) | CA1246545A (en, 2012) |
| CH (1) | CH662569A5 (en, 2012) |
| CY (1) | CY1559A (en, 2012) |
| DE (1) | DE3444367A1 (en, 2012) |
| DK (1) | DK579984A (en, 2012) |
| ES (1) | ES8605279A1 (en, 2012) |
| FI (1) | FI81104C (en, 2012) |
| FR (1) | FR2555989B1 (en, 2012) |
| GB (1) | GB2150931B (en, 2012) |
| GR (1) | GR81159B (en, 2012) |
| HK (1) | HK72590A (en, 2012) |
| IE (1) | IE57832B1 (en, 2012) |
| IT (1) | IT1177370B (en, 2012) |
| LU (1) | LU85670A1 (en, 2012) |
| MY (1) | MY102192A (en, 2012) |
| NL (1) | NL8403670A (en, 2012) |
| SE (1) | SE8406171L (en, 2012) |
| SG (1) | SG48890G (en, 2012) |
| YU (1) | YU45221B (en, 2012) |
| ZA (1) | ZA849415B (en, 2012) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2505697A1 (fr) * | 1981-05-12 | 1982-11-19 | Humblot Bernard | Unite perfectionnee de soudage electrique |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US516047A (en) * | 1894-03-06 | Wire bed-bottom | ||
| US3489752A (en) * | 1967-09-05 | 1970-01-13 | Bristol Myers Co | 7-amino-cephalosporanic and decephalosporanic acid derivatives |
| US3781282A (en) * | 1971-01-20 | 1973-12-25 | W Garbrecht | Cephalosporin process and product |
| US3985741A (en) * | 1972-09-15 | 1976-10-12 | Bristol-Myers Company | Production of p-hydroxycephalexin |
| YU39709B (en) * | 1972-09-15 | 1985-04-30 | Bristol Myers Co | Process for producing cephalosporin |
| DE2317179C2 (de) * | 1973-04-05 | 1982-11-25 | Bristol-Myers Co., 10154 New York, N.Y. | Verfahren zur Herstellung der relativ wasserunlöslichen kristallinen Form von Cefalexinmonohydrat |
| GB1532682A (en) * | 1976-04-27 | 1978-11-22 | Bristol Myers Co | Process for the preparation of cephadroxil |
| JPS5356311A (en) * | 1976-10-28 | 1978-05-22 | Toyama Chem Co Ltd | Cefalexin monohydrate having novel crystal form and process for preparationof the same |
| US4160863A (en) * | 1977-04-07 | 1979-07-10 | Bristol-Myers Company | Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid |
| US4600773A (en) * | 1983-12-01 | 1986-07-15 | Eli Lilly And Company | Crystalline cephalexin hydrochloride monohydrate |
-
1983
- 1983-12-06 FR FR8319463A patent/FR2555989B1/fr not_active Expired
-
1984
- 1984-11-01 CA CA000466852A patent/CA1246545A/en not_active Expired
- 1984-12-03 ZA ZA849415A patent/ZA849415B/xx unknown
- 1984-12-03 GR GR81159A patent/GR81159B/el unknown
- 1984-12-03 NL NL8403670A patent/NL8403670A/nl not_active Application Discontinuation
- 1984-12-03 FI FI844756A patent/FI81104C/fi not_active IP Right Cessation
- 1984-12-04 ES ES538235A patent/ES8605279A1/es not_active Expired
- 1984-12-05 SE SE8406171A patent/SE8406171L/ not_active Application Discontinuation
- 1984-12-05 JP JP59255860A patent/JPH0794461B2/ja not_active Expired - Lifetime
- 1984-12-05 CH CH5786/84A patent/CH662569A5/fr not_active IP Right Cessation
- 1984-12-05 AU AU36321/84A patent/AU567780B2/en not_active Ceased
- 1984-12-05 LU LU85670A patent/LU85670A1/fr unknown
- 1984-12-05 IT IT23909/84A patent/IT1177370B/it active
- 1984-12-05 BE BE0/214120A patent/BE901218A/fr not_active IP Right Cessation
- 1984-12-05 GB GB08430753A patent/GB2150931B/en not_active Expired
- 1984-12-05 DE DE19843444367 patent/DE3444367A1/de active Granted
- 1984-12-05 IE IE3117/84A patent/IE57832B1/en not_active IP Right Cessation
- 1984-12-05 DK DK579984A patent/DK579984A/da not_active Application Discontinuation
- 1984-12-05 AT AT0386384A patent/AT386411B/de not_active IP Right Cessation
- 1984-12-06 KR KR1019840007701A patent/KR920001769B1/ko not_active Expired
- 1984-12-07 YU YU2073/84A patent/YU45221B/xx unknown
-
1987
- 1987-10-01 MY MYPI87002829A patent/MY102192A/en unknown
-
1990
- 1990-07-04 SG SG48890A patent/SG48890G/en unknown
- 1990-09-13 HK HK725/90A patent/HK72590A/xx unknown
-
1991
- 1991-03-22 CY CY1559A patent/CY1559A/en unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed | ||
| MM | Patent lapsed |
Owner name: BRISTOL-MYERS SQUIBB COMPANY |