FI75804C - Foerfarande foer framstaellning av terapeutiskt aktivt prolinderivat. - Google Patents

Foerfarande foer framstaellning av terapeutiskt aktivt prolinderivat. Download PDF

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Publication number
FI75804C
FI75804C FI822171A FI822171A FI75804C FI 75804 C FI75804 C FI 75804C FI 822171 A FI822171 A FI 822171A FI 822171 A FI822171 A FI 822171A FI 75804 C FI75804 C FI 75804C
Authority
FI
Finland
Prior art keywords
group
compound
formula
mixture
cyclohexylcarbonyl
Prior art date
Application number
FI822171A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI822171A0 (fi
FI822171L (fi
FI75804B (fi
Inventor
Sadao Tanaka
Kiyonori Kuromaru
Yasuo Fujimura
Isao Matsunaga
Tomoyasu Iwaoka
Noriko Obatake
Junichiro Aono
Yoshikazu Hinohara
Hideki Nakano
Masafumi Fukushima
Hiroyuki Nabata
Kazushige Sakai
Shun-Ichi Hata
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP56094002A external-priority patent/JPS57209270A/ja
Priority claimed from JP56137823A external-priority patent/JPS5839661A/ja
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of FI822171A0 publication Critical patent/FI822171A0/fi
Publication of FI822171L publication Critical patent/FI822171L/fi
Publication of FI75804B publication Critical patent/FI75804B/fi
Application granted granted Critical
Publication of FI75804C publication Critical patent/FI75804C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI822171A 1981-06-19 1982-06-16 Foerfarande foer framstaellning av terapeutiskt aktivt prolinderivat. FI75804C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP56094002A JPS57209270A (en) 1981-06-19 1981-06-19 Proline derivative
JP9400281 1981-06-19
JP13782381 1981-09-03
JP56137823A JPS5839661A (ja) 1981-09-03 1981-09-03 プロリン誘導体の製法

Publications (4)

Publication Number Publication Date
FI822171A0 FI822171A0 (fi) 1982-06-16
FI822171L FI822171L (fi) 1982-12-20
FI75804B FI75804B (fi) 1988-04-29
FI75804C true FI75804C (fi) 1988-08-08

Family

ID=26435270

Family Applications (1)

Application Number Title Priority Date Filing Date
FI822171A FI75804C (fi) 1981-06-19 1982-06-16 Foerfarande foer framstaellning av terapeutiskt aktivt prolinderivat.

Country Status (19)

Country Link
KR (1) KR890000769B1 (fr)
AT (1) AT377496B (fr)
CA (1) CA1235120A (fr)
CH (1) CH651825A5 (fr)
DE (1) DE3222779A1 (fr)
DK (1) DK156054C (fr)
ES (2) ES8307216A1 (fr)
FI (1) FI75804C (fr)
FR (1) FR2508040B1 (fr)
GB (1) GB2102412B (fr)
HU (1) HU188177B (fr)
IL (1) IL65954A (fr)
IT (1) IT1157053B (fr)
MX (2) MX171888B (fr)
NL (1) NL193282C (fr)
NO (1) NO156408C (fr)
PT (1) PT75076B (fr)
SE (1) SE453595B (fr)
SU (1) SU1316556A3 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6354321A (ja) * 1985-03-27 1988-03-08 Ajinomoto Co Inc 血糖降下剤
US4783334A (en) * 1986-01-21 1988-11-08 Chugai Seiyaku Kabushiki Kaisha Stable solid preparation of thiol ester derivative
ZA896851B (en) 1988-09-14 1990-06-27 Hoffmann La Roche Use of ace-inhibitors
PT634175E (pt) * 1993-07-15 2001-06-29 Hoffmann La Roche Combinacao farmaceutica que contem um inibidor do sistema renina-angiotensina e o antagonista de endotelina

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA802420B (en) * 1979-05-18 1981-04-29 Squibb & Sons Inc Aminoacyl derivatives of mercaptoacyl amino acids

Also Published As

Publication number Publication date
SE8203814L (sv) 1982-12-20
IT1157053B (it) 1987-02-11
FR2508040B1 (fr) 1986-07-04
FI822171A0 (fi) 1982-06-16
DK156054C (da) 1989-11-06
MX171888B (es) 1993-11-23
MX155724A (es) 1988-04-20
IL65954A0 (en) 1982-09-30
ES513277A0 (es) 1983-07-01
SE453595B (sv) 1988-02-15
CA1235120A (fr) 1988-04-12
DE3222779C2 (fr) 1991-01-03
NO821997L (no) 1982-12-20
CH651825A5 (de) 1985-10-15
ES520582A0 (es) 1984-04-01
NO156408B (no) 1987-06-09
FR2508040A1 (fr) 1982-12-24
SU1316556A3 (ru) 1987-06-07
ES8403868A1 (es) 1984-04-01
IL65954A (en) 1986-03-31
ES8307216A1 (es) 1983-07-01
DK273082A (da) 1982-12-20
GB2102412A (en) 1983-02-02
NL193282C (nl) 1999-05-06
NL8202472A (nl) 1983-01-17
NL193282B (nl) 1999-01-04
FI822171L (fi) 1982-12-20
AT377496B (de) 1985-03-25
ATA558581A (de) 1984-08-15
HU188177B (en) 1986-03-28
PT75076B (en) 1984-05-09
KR890000769B1 (ko) 1989-04-05
NO156408C (no) 1987-09-16
PT75076A (en) 1982-07-01
DE3222779A1 (de) 1983-01-27
FI75804B (fi) 1988-04-29
GB2102412B (en) 1985-01-09
IT8267772A0 (it) 1982-06-16
DK156054B (da) 1989-06-19
KR840000488A (ko) 1984-02-22

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MM Patent lapsed

Owner name: CHUGAI SEIYAKU KABUSHIKI KAISHA