FI750256A - - Google Patents

Info

Publication number
FI750256A
FI750256A FI750256A FI750256A FI750256A FI 750256 A FI750256 A FI 750256A FI 750256 A FI750256 A FI 750256A FI 750256 A FI750256 A FI 750256A FI 750256 A FI750256 A FI 750256A
Authority
FI
Finland
Application number
FI750256A
Other languages
Finnish (fi)
Other versions
FI63744B (fi
FI63744C (fi
Inventor
Francesco Makovec
Luigi Rovatti
Paolo Senin
Original Assignee
Rotta Research Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rotta Research Lab filed Critical Rotta Research Lab
Publication of FI750256A publication Critical patent/FI750256A/fi
Publication of FI63744B publication Critical patent/FI63744B/fi
Application granted granted Critical
Publication of FI63744C publication Critical patent/FI63744C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/192Radicals derived from carboxylic acids from aromatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI750256A 1974-02-01 1975-01-30 Foerfarande foer framstaellning av nya spasmolytiska tyrosinderivat FI63744C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT67286/74A IT1062206B (it) 1974-02-01 1974-02-01 Derivati della tirosina attivi sulla muscolatura liscia
IT6728674 1974-02-01

Publications (3)

Publication Number Publication Date
FI750256A true FI750256A (pt) 1975-08-02
FI63744B FI63744B (fi) 1983-04-29
FI63744C FI63744C (fi) 1983-08-10

Family

ID=11301149

Family Applications (2)

Application Number Title Priority Date Filing Date
FI750255A FI61479C (fi) 1974-02-01 1975-01-30 Foerfarande foer framstaellning av spasmolytiska nya d,l-tyrosinderivat
FI750256A FI63744C (fi) 1974-02-01 1975-01-30 Foerfarande foer framstaellning av nya spasmolytiska tyrosinderivat

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI750255A FI61479C (fi) 1974-02-01 1975-01-30 Foerfarande foer framstaellning av spasmolytiska nya d,l-tyrosinderivat

Country Status (19)

Country Link
US (1) US4004008A (pt)
JP (2) JPS5417728B2 (pt)
AT (2) AT343632B (pt)
BE (1) BE824995A (pt)
CA (2) CA1047498A (pt)
CH (2) CH605658A5 (pt)
DE (1) DE2503992C2 (pt)
ES (1) ES434323A1 (pt)
FI (2) FI61479C (pt)
FR (1) FR2259592B1 (pt)
GB (1) GB1467927A (pt)
HK (1) HK38979A (pt)
HU (2) HU174825B (pt)
IN (1) IN139364B (pt)
IT (1) IT1062206B (pt)
NL (1) NL167683C (pt)
NO (2) NO144211C (pt)
SE (2) SE413094B (pt)
ZA (1) ZA75530B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5225243A (en) * 1975-08-20 1977-02-25 Toshiba Electric Equip Corp Distributing panel
US4579866A (en) * 1984-05-29 1986-04-01 Usv Pharmaceutical Corp. Phenylacetamides as anti-allergy, anti-asthma and anti-inflammatory agents
US5198458A (en) * 1986-02-04 1993-03-30 Suntory Limited Pyrrolidineamide derivatives of acylamino acid and pharmaceutical composition containing the same
CA1320734C (en) * 1986-02-04 1993-07-27 Suntory Limited Pyrrolidineamide derivative of acylamino acid and pharmaceutical composition containing the same
NZ239846A (en) * 1990-09-27 1994-11-25 Merck & Co Inc Sulphonamide derivatives and pharmaceutical compositions thereof
IL99537A (en) * 1990-09-27 1995-11-27 Merck & Co Inc Fibrinogen receptor antagonists and pharmaceutical preparations containing them
US5258407A (en) * 1991-12-31 1993-11-02 Sterling Winthrop Inc. 3,4-disubstituted phenols-immunomodulating agents
US5206373A (en) * 1992-02-28 1993-04-27 Merck & Co., Inc. Process for preparing fibrinogen receptor antagonists
DE10204951A1 (de) * 2002-02-06 2003-08-14 Basf Ag Phenylalaninderivate als Herbizide
EA200601105A1 (ru) * 2003-12-19 2006-12-29 Басф Акциенгезельшафт Замещённые бензоилом фенилаланин-амиды
WO2007010885A1 (ja) 2005-07-19 2007-01-25 Daiichi Sankyo Company, Limited 置換プロパンアミド誘導体及びそれを含む医薬組成物
WO2011094890A1 (en) 2010-02-02 2011-08-11 Argusina Inc. Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators
WO2011156655A2 (en) * 2010-06-09 2011-12-15 Receptos, Inc. Novel glp-1 receptor stabilizers and modulators
PT2713722T (pt) 2011-05-31 2017-06-27 Receptos Llc Novos estabilizadores e moduladores do receptor glp-1
AU2012352349B2 (en) 2011-12-12 2017-08-17 Receptos Llc Carboxylic acid derivatives comprising four cycles acting as GLP-1 receptor modulators for therapy of diseases such as diabetes
CN102659619A (zh) * 2012-04-18 2012-09-12 上海骏捷生化科技有限公司 一种合成酪氨酸衍生物的方法
CN103508921B (zh) * 2012-06-21 2015-09-30 贵州百灵企业集团制药股份有限公司 一种苯丙氨醇化合物的制备方法
CN103508920B (zh) * 2012-06-21 2016-03-02 贵州百灵企业集团制药股份有限公司 一种苯丙氨醇化合物的光学异构体的制备方法及其用途
EP3008056B8 (en) 2013-06-11 2021-03-03 Receptos Llc Novel glp-1 receptor modulators
CN112457301A (zh) 2014-07-25 2021-03-09 赛尔基因第二国际有限公司 新的glp-1受体调节剂
WO2016094729A1 (en) 2014-12-10 2016-06-16 Celgene International Ii Sarl Glp-1 receptor modulators
CN107417560B (zh) * 2017-03-30 2020-05-22 上海常丰生物医药科技有限公司 一种合成盐酸替罗酰胺的方法
CN110015978B (zh) * 2019-04-29 2021-03-19 康化(上海)新药研发有限公司 O-[2-[[叔丁氧羰基]氨基]乙基]-n-[芴甲氧羰基]-l-酪氨酸的合成方法
CN115850107A (zh) * 2022-11-30 2023-03-28 苏州诚和医药化学有限公司 一种工业化合成盐酸替罗酰胺的方法

Also Published As

Publication number Publication date
CH605657A5 (pt) 1978-10-13
JPS50116441A (pt) 1975-09-11
AT343632B (de) 1978-06-12
CA1048503A (en) 1979-02-13
IT1062206B (it) 1983-09-20
ZA75530B (en) 1976-01-28
FI61479B (fi) 1982-04-30
NO750287L (pt) 1975-08-25
SE7501114L (sv) 1975-08-04
CH605658A5 (pt) 1978-10-13
ATA74675A (de) 1977-10-15
DE2503992C2 (de) 1982-01-21
ES434323A1 (es) 1976-12-16
CA1047498A (en) 1979-01-30
NO144211C (no) 1981-07-15
HU174825B (hu) 1980-03-28
HU175156B (hu) 1980-05-28
JPS5417728B2 (pt) 1979-07-02
DE2503992A1 (de) 1975-08-14
JPS50116442A (pt) 1975-09-11
SE413094B (sv) 1980-04-14
FR2259592A1 (pt) 1975-08-29
BE824995A (fr) 1975-05-15
GB1467927A (en) 1977-03-23
US4004008A (en) 1977-01-18
ATA74575A (de) 1977-07-15
SE410850B (sv) 1979-11-12
HK38979A (en) 1979-06-22
FI63744B (fi) 1983-04-29
FI750255A (pt) 1975-08-02
NO144210B (no) 1981-04-06
FI63744C (fi) 1983-08-10
AT342026B (de) 1978-03-10
NO144211B (no) 1981-04-06
NO144210C (no) 1981-07-15
AU7775075A (en) 1976-08-05
NL167683C (nl) 1982-01-18
NL167683B (nl) 1981-08-17
FR2259592B1 (pt) 1978-07-21
IN139364B (pt) 1976-06-12
NL7501193A (nl) 1975-08-05
FI61479C (fi) 1982-08-10
JPS5417729B2 (pt) 1979-07-02
NO750288L (pt) 1975-08-25
SE7501115L (sv) 1975-08-04

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: ROTTA RESEARCH LABORATORIUM S.P.A.