FI74009C - Foerfarande foer framstaellning av terapeutiskt anvaendbart 3-/2-(1-tetrahydrotiofenium)etyltio/-6- -/1- (r)-hydroxietyl/-7-oxo-1-azabicyklo/3.2.0/hepten-2-en-2-karboxylat. - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbart 3-/2-(1-tetrahydrotiofenium)etyltio/-6- -/1- (r)-hydroxietyl/-7-oxo-1-azabicyklo/3.2.0/hepten-2-en-2-karboxylat. Download PDF

Info

Publication number
FI74009C
FI74009C FI831135A FI831135A FI74009C FI 74009 C FI74009 C FI 74009C FI 831135 A FI831135 A FI 831135A FI 831135 A FI831135 A FI 831135A FI 74009 C FI74009 C FI 74009C
Authority
FI
Finland
Prior art keywords
formula
compound
inert organic
alkyl
give
Prior art date
Application number
FI831135A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI831135L (fi
FI74009B (fi
FI831135A0 (fi
Inventor
Choung Un Kim
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI831135A0 publication Critical patent/FI831135A0/fi
Publication of FI831135L publication Critical patent/FI831135L/fi
Publication of FI74009B publication Critical patent/FI74009B/fi
Application granted granted Critical
Publication of FI74009C publication Critical patent/FI74009C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI831135A 1982-04-08 1983-04-05 Foerfarande foer framstaellning av terapeutiskt anvaendbart 3-/2-(1-tetrahydrotiofenium)etyltio/-6- -/1- (r)-hydroxietyl/-7-oxo-1-azabicyklo/3.2.0/hepten-2-en-2-karboxylat. FI74009C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36662782A 1982-04-08 1982-04-08
US36662782 1982-04-08

Publications (4)

Publication Number Publication Date
FI831135A0 FI831135A0 (fi) 1983-04-05
FI831135L FI831135L (fi) 1983-10-09
FI74009B FI74009B (fi) 1987-08-31
FI74009C true FI74009C (fi) 1987-12-10

Family

ID=23443823

Family Applications (1)

Application Number Title Priority Date Filing Date
FI831135A FI74009C (fi) 1982-04-08 1983-04-05 Foerfarande foer framstaellning av terapeutiskt anvaendbart 3-/2-(1-tetrahydrotiofenium)etyltio/-6- -/1- (r)-hydroxietyl/-7-oxo-1-azabicyklo/3.2.0/hepten-2-en-2-karboxylat.

Country Status (25)

Country Link
JP (1) JPS58188887A (da)
KR (1) KR880001055B1 (da)
AT (1) AT383126B (da)
AU (1) AU567092B2 (da)
BE (1) BE896407A (da)
CA (1) CA1198440A (da)
CH (1) CH661927A5 (da)
DE (1) DE3312517A1 (da)
DK (1) DK155983A (da)
ES (1) ES521224A0 (da)
FI (1) FI74009C (da)
FR (1) FR2524888B1 (da)
GB (1) GB2118183B (da)
GR (1) GR78822B (da)
HU (1) HU190716B (da)
IE (1) IE55225B1 (da)
IL (1) IL68295A0 (da)
IT (1) IT1168854B (da)
LU (1) LU84739A1 (da)
MY (1) MY8700945A (da)
NL (1) NL8301193A (da)
OA (1) OA07395A (da)
PT (1) PT76518B (da)
SE (1) SE460197B (da)
ZA (1) ZA832411B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683301A (en) * 1982-04-08 1987-07-28 Bristol-Myers Company Carbapenem antibiotics
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
AT396473B (de) * 1984-10-02 1993-09-27 Bristol Myers Squibb Co Verfahren zur herstellung von neuen carbapenemderivaten
US4665169A (en) * 1985-09-11 1987-05-12 Bristol-Myers Company Carbapenem antibiotics

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU531084B2 (en) * 1977-10-19 1983-08-11 Merck & Co., Inc. Azetidine derivatives
EP0082133A3 (en) * 1979-04-19 1983-07-20 Merck & Co. Inc. A process for preparing intermediates useful for preparing 2-substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids
EP0038869A1 (en) * 1980-04-30 1981-11-04 Merck & Co. Inc. Process for the preparation of 1-carbapenems, and intermediates for their preparation
HU185493B (en) * 1981-12-30 1985-02-28 Richter Gedeon Vegyeszet Process for producing new azabicyclo-bracket-3.2.0-bracket closedheptene derivatives
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics

Also Published As

Publication number Publication date
JPS58188887A (ja) 1983-11-04
ES8405399A1 (es) 1984-06-01
PT76518B (en) 1986-02-06
ATA125583A (de) 1986-10-15
IE55225B1 (en) 1990-07-04
SE8301928L (sv) 1983-12-02
IT1168854B (it) 1987-05-20
GB8309505D0 (en) 1983-05-11
GR78822B (da) 1984-10-02
DE3312517C2 (da) 1991-10-31
DK155983D0 (da) 1983-04-07
IE830800L (en) 1983-10-08
OA07395A (fr) 1984-06-30
ES521224A0 (es) 1984-06-01
SE8301928D0 (sv) 1983-04-07
FI831135L (fi) 1983-10-09
FR2524888A1 (fr) 1983-10-14
AT383126B (de) 1987-05-25
KR840004429A (ko) 1984-10-15
FI74009B (fi) 1987-08-31
LU84739A1 (fr) 1983-12-05
CA1198440A (en) 1985-12-24
CH661927A5 (de) 1987-08-31
BE896407A (fr) 1983-10-07
KR880001055B1 (ko) 1988-06-18
DE3312517A1 (de) 1983-10-20
ZA832411B (en) 1983-12-28
IL68295A0 (en) 1983-07-31
AU1319883A (en) 1983-10-13
FR2524888B1 (fr) 1985-12-13
AU567092B2 (en) 1987-11-12
IT8348061A0 (it) 1983-04-07
PT76518A (en) 1983-05-01
SE460197B (sv) 1989-09-18
MY8700945A (en) 1987-12-31
FI831135A0 (fi) 1983-04-05
DK155983A (da) 1983-10-09
GB2118183B (en) 1985-11-27
JPH0524156B2 (da) 1993-04-06
GB2118183A (en) 1983-10-26
HU190716B (en) 1986-10-28
NL8301193A (nl) 1983-11-01

Similar Documents

Publication Publication Date Title
US4536335A (en) Carbapenem antibiotics
EP0474243B1 (en) 1-Methylcarbapenem derivatives and process for preparation thereof
CA1283659C (en) Carbapenem antibiotics
FI74009C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbart 3-/2-(1-tetrahydrotiofenium)etyltio/-6- -/1- (r)-hydroxietyl/-7-oxo-1-azabicyklo/3.2.0/hepten-2-en-2-karboxylat.
KR890002228B1 (ko) 카르바페넴 유도체 및 그의 제조방법
EP0235823B1 (en) Carbapenem antibiotics, a process for preparing them and pharmaceutical compositions containing them
US4880922A (en) Carbapenems with quaternized heterothioalkylthio substitution at position 2
US4640799A (en) Carbapenem antibiotics
KR910009270B1 (ko) 카바펜엠 항생제의 제조방법
US4665170A (en) Carbapenem antibiotics
JP4598273B2 (ja) カルバペネム−３−カルボン酸の新規Ｃ−２Ｓ／Ｏ−及びＳ／Ｎホルムアルデヒドアセタール誘導体並びにそれらの抗生物質及びβ−ラクタマーゼインヒビターとしての使用
KR910006807B1 (ko) 카바펜엠 항생제의 제조방법
EP0545290A1 (en) Aminoalkylpyrrolidinylthiocarbapenem derivatives
JPH0429675B2 (da)
KR100191705B1 (ko) 신규한 피롤리디닐 티오 카바페넴 유도체 및 그의 제조방법
CS247195B2 (cs) Způsob výroby karbapenemderivátů

Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: BRISTOL-MYERS CO