FI71153C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 7-/3,6-dihydro-1h(2h)-pyridyl/-2-oxo-2h/1,2,4/-oxadiazolo-/2,3-c/pyrimidin-5-karbamat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 7-/3,6-dihydro-1h(2h)-pyridyl/-2-oxo-2h/1,2,4/-oxadiazolo-/2,3-c/pyrimidin-5-karbamat Download PDF

Info

Publication number
FI71153C
FI71153C FI814048A FI814048A FI71153C FI 71153 C FI71153 C FI 71153C FI 814048 A FI814048 A FI 814048A FI 814048 A FI814048 A FI 814048A FI 71153 C FI71153 C FI 71153C
Authority
FI
Finland
Prior art keywords
dihydro
oxadiazolo
formula
oxo
carbamate
Prior art date
Application number
FI814048A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI814048L (fi
FI71153B (fi
Inventor
Urs Hengartner
Jean-Claude Muller
Henri Ramuz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI814048L publication Critical patent/FI814048L/fi
Application granted granted Critical
Publication of FI71153B publication Critical patent/FI71153B/fi
Publication of FI71153C publication Critical patent/FI71153C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI814048A 1980-12-19 1981-12-16 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 7-/3,6-dihydro-1h(2h)-pyridyl/-2-oxo-2h/1,2,4/-oxadiazolo-/2,3-c/pyrimidin-5-karbamat FI71153C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH941080 1980-12-19
CH941080 1980-12-19
CH635081 1981-10-02
CH635081 1981-10-02

Publications (3)

Publication Number Publication Date
FI814048L FI814048L (fi) 1982-06-20
FI71153B FI71153B (fi) 1986-08-14
FI71153C true FI71153C (fi) 1986-11-24

Family

ID=25699419

Family Applications (1)

Application Number Title Priority Date Filing Date
FI814048A FI71153C (fi) 1980-12-19 1981-12-16 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 7-/3,6-dihydro-1h(2h)-pyridyl/-2-oxo-2h/1,2,4/-oxadiazolo-/2,3-c/pyrimidin-5-karbamat

Country Status (23)

Country Link
US (2) US4410698A (da)
EP (1) EP0054866B1 (da)
KR (1) KR880001636B1 (da)
AR (1) AR229169A1 (da)
AT (1) ATE14734T1 (da)
AU (1) AU545324B2 (da)
BR (1) BR8108269A (da)
CA (1) CA1162538A (da)
CS (1) CS226738B2 (da)
DE (1) DE3171744D1 (da)
DK (1) DK148826C (da)
ES (1) ES8304125A1 (da)
FI (1) FI71153C (da)
GR (1) GR76969B (da)
HU (1) HU183744B (da)
IE (1) IE51800B1 (da)
IL (1) IL64524A (da)
MC (1) MC1438A1 (da)
NO (1) NO158422C (da)
NZ (1) NZ199250A (da)
PH (1) PH17300A (da)
PT (1) PT74153B (da)
ZW (1) ZW28581A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK148826C (da) * 1980-12-19 1986-03-24 Hoffmann La Roche Analogifremgangsmaade til fremstilling af oxadiazolopyrimidinderivater eller salte deraf med baser og pyrimidinderivat til anvendelse som mellemprodukt ved denne fremgangsmaade
CH649291A5 (de) * 1982-03-16 1985-05-15 Hoffmann La Roche Dicarbamate.
EP0187854A4 (en) * 1984-07-13 1987-01-22 Gail S Bazzano SUBSTITUTED PYRIMIDINE OXIDES USEFUL FOR PROMOTING HAIR GROWTH.
LU86959A1 (fr) * 1987-07-31 1989-03-08 Oreal Nouveaux derives d'ureylene triamino-2,4,6 pyrimidine oxyde-3,leur preparation et leur utilisation en cosmetique et dermopharmacie
EP0915854B1 (en) * 1996-07-26 2002-09-25 Vantico AG Curable mixtures based on epoxy resins comprising imidazoles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH638215A5 (de) * 1977-02-04 1983-09-15 Hoffmann La Roche Oxadiazolopyrimidin-derivate.
CH638216A5 (de) * 1977-02-04 1983-09-15 Hoffmann La Roche Oxadiazolopyrimidin-deriate.
CA1103245A (en) * 1978-07-21 1981-06-16 Jean-Claude Muller Process for the manufacture of novel oxadiazolopyrimidine derivatives
NZ190915A (en) * 1978-07-31 1984-07-31 Hoffmann La Roche Oxadiazolotriazine derivatives and pharmaceutical compositions
DK148826C (da) * 1980-12-19 1986-03-24 Hoffmann La Roche Analogifremgangsmaade til fremstilling af oxadiazolopyrimidinderivater eller salte deraf med baser og pyrimidinderivat til anvendelse som mellemprodukt ved denne fremgangsmaade

Also Published As

Publication number Publication date
BR8108269A (pt) 1982-10-05
NO814359L (no) 1982-06-21
EP0054866A3 (en) 1982-09-01
FI814048L (fi) 1982-06-20
IE51800B1 (en) 1987-04-01
IE812990L (en) 1982-06-19
ES508152A0 (es) 1983-02-16
AU545324B2 (en) 1985-07-11
ATE14734T1 (de) 1985-08-15
EP0054866B1 (de) 1985-08-07
NZ199250A (en) 1984-04-27
AR229169A1 (es) 1983-06-30
MC1438A1 (fr) 1982-12-06
ZW28581A1 (en) 1982-08-11
CS226738B2 (en) 1984-04-16
US4410698A (en) 1983-10-18
PT74153A (en) 1982-01-01
DK148826C (da) 1986-03-24
DK504881A (da) 1982-06-20
EP0054866A2 (de) 1982-06-30
IL64524A (en) 1985-05-31
NO158422B (no) 1988-05-30
FI71153B (fi) 1986-08-14
GR76969B (da) 1984-09-04
IL64524A0 (en) 1982-03-31
PH17300A (en) 1984-07-18
DE3171744D1 (en) 1985-09-12
AU7846481A (en) 1982-06-24
KR880001636B1 (ko) 1988-09-03
US4360521A (en) 1982-11-23
HU183744B (en) 1984-05-28
DK148826B (da) 1985-10-14
NO158422C (no) 1988-09-07
PT74153B (en) 1984-01-05
ES8304125A1 (es) 1983-02-16
CA1162538A (en) 1984-02-21

Similar Documents

Publication Publication Date Title
EP0230942B1 (de) Thieno-1,4-diazepine
FI79299B (fi) Foerfarande foer framstaellning av terapeutiskt aktiva tetrahydrobensindoler.
US4609494A (en) 5-acetyl-3,4,5,6-tetrahydro-4-oxo-2,6-methano-2H-1,3,5-benzothiazocine(benzodiazocine)-11-carboxylates useful as calcium channel blockers
EP0045161A1 (en) Amides of 4-oxo-5-amidohexanoic acid derivatives
IE832058L (en) 1,4-dihydropyridine derivatives
NZ280745A (en) 1,2,4,5-tetrahydro-4-alkyl-7,8-methylenedioxy-5-oxo-3-benzothiepine derivatives; intermediates
FI71153C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 7-/3,6-dihydro-1h(2h)-pyridyl/-2-oxo-2h/1,2,4/-oxadiazolo-/2,3-c/pyrimidin-5-karbamat
HU198713B (en) Process for producing ergolin derivatives and pharmaceutical compositions containing them as active components
FR2645022A1 (fr) Compositions therapeutiques a base de derives de la thieno-triazolo-diazepine
DE3701344A1 (de) Neue thieno-1,4-diazepine
JP2002523499A (ja) ピラジン化合物
FR2549061A1 (fr) Derives du spirosuccinimide utilisables comme medicaments
FI81100C (fi) Foerfarande foer framstaellning av terapeutiskt aktiva 1,4,5,7-tetrahydrofuro/3,4-b/pyridinderivat.
CA1076580A (en) 2,3,6,7-tetrahydro-5h-pyrrolo-(1,2-a)imidazole compounds
FI78099B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara imidazo/1,2-c/pyrimidinderivat.
IE840054L (en) Compounds
CS208463B2 (en) Method of making the 4-/n-acetyl/amino-tetrahydro-1,3,5-triazine-2,6-dions
US4250180A (en) Method of treating arrhythmia
CA1300149C (en) 1,3-dihydro-6-(1-hydroxy-2-dimethylaminomethyl-allyl)-7- hydroxy-furo-(3,4-c)-pyridine derivatives
JPH04221386A (ja) ４Ｈ−ピロロ［１，２−ａ］チエノ［２，３−ｆ］［１，４］ジアゼピンの新規誘導体、それらの製造方法及びこれらを含有する医薬品組成物
US5143915A (en) Dihydropyrimidine macrocyclic lactones useful as calcium antagonists and agonists
IE48176B1 (en) Ergot peptide alkaloid derivatives,processes for their preparation and pharmaceutical compositions containing them
US3945960A (en) Antiinflammatory and analgesic cycloalkano-pyrimidin-2(1H)-ones
JPH04234889A (ja) ４Ｈ−ピロロ〔１，２−ａ〕チエノ〔３，２−ｆ〕〔１，４〕ジアゼピンの新規誘導体およびその製造方法
KR840001284B1 (ko) 2-이미다졸린 유도체류의 제조방법

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE AG