DE3131146A1
(de)
*
|
1981-08-06 |
1983-02-24 |
Boehringer Mannheim Gmbh, 6800 Mannheim |
Neue heteroaryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
|
DE3300933A1
(de)
*
|
1983-01-13 |
1984-07-19 |
Boehringer Mannheim Gmbh, 6800 Mannheim |
Verwendung von d,l- und d-carazolol als antiglaukommittel sowie arzneimittel, die diese stoffe enthalten
|
DE3319027A1
(de)
*
|
1983-05-26 |
1984-11-29 |
Boehringer Mannheim Gmbh, 6800 Mannheim |
Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten
|
ZA938897B
(en)
*
|
1992-12-01 |
1994-08-01 |
Smithkline Beecham Corp |
Antioxidant neuroprotective use of and method of treatment using hydroxycarbazole compounds
|
US5405863A
(en)
*
|
1992-12-01 |
1995-04-11 |
Smithkline Beecham Corporation |
Antioxidant cardioprotective use of, and method of treatment using, hydroxycarbazole compounds
|
US5308862A
(en)
*
|
1993-03-05 |
1994-05-03 |
Boehringer Mannheim Pharmaceuticals Corporation - Smithkline Beecham Corp., Ltd. Partnership No. 1 |
Use of, and method of treatment using, carbazolyl-(4)-oxypropanolamine compounds for inhibition of smooth muscle cell proliferation
|
WO1994020096A1
(fr)
*
|
1993-03-05 |
1994-09-15 |
Boehringer Mannheim Pharmaceuticals Corporation - Smithkline Beckman Corporation Limited |
Procede d'utilisation de carbazolyle-(4)-oxypropanolamine pour inhiber la proliferation de cellules de muscles lisses
|
US5393772A
(en)
*
|
1993-11-24 |
1995-02-28 |
Boehringer Mannheim Pharmaceuticals Corporation |
Use of, and method of treatment using, hydroxycarbazole compounds for inhibition of smooth muscle migration and proliferation
|
US5760069A
(en)
|
1995-02-08 |
1998-06-02 |
Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beecham Corporation Limited Partnership #1 |
Method of treatment for decreasing mortality resulting from congestive heart failure
|
ZA967892B
(en)
*
|
1995-09-21 |
1998-03-18 |
Lilly Co Eli |
Selective β3 adrenergic agonists.
|
US6177430B1
(en)
|
1997-03-27 |
2001-01-23 |
Pfizer Inc |
Use of α1-adrenoreceptor antagonists in the prevention and treatment of benign prostatic hyperplasia
|
DE19628335A1
(de)
*
|
1996-07-13 |
1998-01-15 |
Boehringer Mannheim Gmbh |
Verwendung von Carbazolyl-(4)-oxy-propanolamin-Derivaten zur topischen Behandlung von peripheren Durchblutungsstörungen
|
WO1998007321A1
(fr)
*
|
1996-08-23 |
1998-02-26 |
Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beckman Corporation Limited Partnership No. 1 |
METHODE POUR INHIBER L'EXPRESSION DE Fas
|
EP0827746B1
(fr)
*
|
1996-09-05 |
2002-04-03 |
Eli Lilly And Company |
Analogues de carbazole étant agonistes beta3-adrénergiques sélectifs
|
US5808080A
(en)
*
|
1996-09-05 |
1998-09-15 |
Eli Lilly And Company |
Selective β3 adrenergic agonists
|
BR9712283A
(pt)
*
|
1996-10-09 |
1999-08-31 |
Boehringer Mannheim Pharm Corp |
Método para inibir as cinases de proteìnas ativadas por tensão
|
US6730326B2
(en)
|
1997-07-22 |
2004-05-04 |
Roche Diagnostics Gmbh |
Thermodynamically stable modification of 1-(4-carbazolyl-oxy-3[2-(2-methoxyphenoxy)-ethylamino]-2-propanol process for its preparation and pharmaceutical compositions containing it
|
EP0893440A1
(fr)
*
|
1997-07-22 |
1999-01-27 |
Roche Diagnostics GmbH |
Une modification thermodynamique stabilisée de 1-(4-carbazolyloxy)-3[2-(2-methoxyphenoxy)ethylamino]- 2-propanole, un procédé pour sa préparation et une composition pharmaceutique qui la contient
|
ZA989365B
(en)
*
|
1997-10-15 |
1999-04-15 |
Boehringer Mannheim Pharm Corp |
Preparation for treating alzheimer's disease
|
HUP0004345A3
(en)
*
|
1997-11-12 |
2001-10-29 |
Boehringer Mannheim Pharm Corp |
Novel oral pharmaceutical compositions containing from carvedilol
|
HU227441B1
(en)
*
|
1997-11-24 |
2011-06-28 |
Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag |
Process for producing carvedilol, enantiomers and salts thereof
|
CO5011072A1
(es)
|
1997-12-05 |
2001-02-28 |
Lilly Co Eli |
Etanolaminas pirazinil substituidas como agfonistas de los receptores
|
EP0968714A1
(fr)
*
|
1998-07-02 |
2000-01-05 |
Roche Diagnostics GmbH |
Procédé de préparation de compositions pharmaceutiques à dissolution rapide contenant des agents actifs difficilement solubles
|
ES2204121T3
(es)
*
|
1998-04-09 |
2004-04-16 |
Roche Diagnostics Gmbh |
Carvedilol-galenicos.
|
DE19833119A1
(de)
*
|
1998-07-23 |
2000-01-27 |
Roche Diagnostics Gmbh |
Spritzfertige Injektionslösungen enthaltend Carvedilol
|
US6664284B2
(en)
|
1998-07-23 |
2003-12-16 |
Roche Diagnostics Gmbh |
Stabilized carvedilol injection solution
|
US6291506B1
(en)
|
1998-08-04 |
2001-09-18 |
Wisconsin Alumni Research Foundation |
Method of reducing retinal ganglion cell degeneration
|
PE20001302A1
(es)
|
1998-11-27 |
2000-11-30 |
Hoffmann La Roche |
Preparaciones de una combinacion farmaceutica que contiene carvedilol e hidroclorotiazida
|
MY125942A
(en)
|
1999-09-07 |
2006-09-29 |
Upjohn Co |
Aminoalkoxy carbazoles for the treatment of cns diseases
|
WO2001035958A1
(fr)
*
|
1999-11-15 |
2001-05-25 |
Smithkline Beecham Corporation |
Methane-sulfonate de carvedilol
|
ES2227206T3
(es)
*
|
2000-04-03 |
2005-04-01 |
F. Hoffmann-La Roche Ag |
Soluciones concentradas de carvedilol.
|
US20010036959A1
(en)
*
|
2000-04-03 |
2001-11-01 |
Gabel Rolf Dieter |
Carvedilol-hydrophilic solutions
|
DK174645B1
(da)
*
|
2000-05-18 |
2003-08-04 |
Gea Farmaceutisk Fabrik As |
Fremgangsmåde og mellemprodukter til fremstillingen af 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxy-phenoxy)-ethylamino]-propan-2-ol, carvedilol og syreadditionssalte deraf
|
EP1655285A1
(fr)
*
|
2000-06-28 |
2006-05-10 |
Teva Pharmaceutical Industries Ltd. |
Procédé de préparation d'une forme crystalline de carvedilol (forme II)
|
CA2413702A1
(fr)
*
|
2000-06-28 |
2002-01-03 |
Teva Pharmaceuticals Industries Ltd. |
Carvedilol
|
GB0106953D0
(en)
*
|
2001-03-20 |
2001-05-09 |
Univ Aberdeen |
Neufofibrillary labels
|
EP1385509A4
(fr)
*
|
2001-04-02 |
2004-06-30 |
Smithkline Beecham Corp |
Methode de traitement
|
IN191028B
(fr)
*
|
2001-05-17 |
2003-09-13 |
Sun Pharmaceutical Ind Ltd |
|
WO2003005970A2
(fr)
*
|
2001-07-13 |
2003-01-23 |
Smithkline Beecham Corporation |
Polymorphe de carvedilol
|
WO2003017046A2
(fr)
*
|
2001-08-14 |
2003-02-27 |
Variant Holdings, Llc. |
Systeme de commercialisation de biens et de services utilisant des installations centrales et distantes informatisees
|
EP2957281A1
(fr)
|
2001-09-21 |
2015-12-23 |
Egalet Ltd. |
Systeme de liberation a base de polymere
|
US20040253310A1
(en)
|
2001-09-21 |
2004-12-16 |
Gina Fischer |
Morphine polymer release system
|
WO2003029214A1
(fr)
*
|
2001-09-28 |
2003-04-10 |
F. Hoffmann-La Roche Ag |
Formes pseudopolymorphes de carvedilol
|
WO2003028718A1
(fr)
*
|
2001-10-01 |
2003-04-10 |
Smithkline Beecham Corporation |
Nouvelles formulations de carvedilol
|
US8101209B2
(en)
*
|
2001-10-09 |
2012-01-24 |
Flamel Technologies |
Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
|
PL371409A1
(en)
*
|
2002-01-15 |
2005-06-13 |
Teva Pharmaceutical Industries Ltd. |
Crystalline solids of carvedilol and processes for their preparation
|
EP2316468A1
(fr)
|
2002-02-22 |
2011-05-04 |
Shire LLC |
Système de distribution et méthodes de protection et d'administration de dextroamphetamine
|
AU2003231283A1
(en)
*
|
2002-04-30 |
2003-11-17 |
Sb Pharmco Puerto Rico Inc. |
Carvedilol monocitrate monohydrate
|
JP2005524701A
(ja)
*
|
2002-05-03 |
2005-08-18 |
エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド |
カルベジロール処方
|
EP1501502A2
(fr)
*
|
2002-05-03 |
2005-02-02 |
SmithKline Beecham Pharmco Puerto Rico, Inc. |
Solvate de carvedilol pharmasolve
|
WO2004002472A1
(fr)
*
|
2002-06-27 |
2004-01-08 |
Sb Pharmco Puerto Rico Inc. |
Hydobromure de carvedilol
|
EA008384B1
(ru)
*
|
2002-06-27 |
2007-04-27 |
Эс Би ФАРМКО ПУЭРТО РИКО ИНК. |
Фосфатные соли карведилола, их сольваты, композиции и способы лечения гипертензии, застойной сердечной недостаточности или стенокардии
|
US20040152756A1
(en)
*
|
2002-07-15 |
2004-08-05 |
Wei Chen |
Carvedilol polymorph
|
US20060013877A1
(en)
*
|
2002-07-22 |
2006-01-19 |
Nanohybrid Co., Ltd. |
Hybrid of itraconazole, cyclosporine or carvedilol with a layered silicate and a process for preparing the same
|
OA12905A
(en)
|
2002-08-19 |
2006-10-13 |
Pfizer Prod Inc |
Combination therapy for hyperproliferative diseases.
|
US6632832B1
(en)
|
2002-09-10 |
2003-10-14 |
Dabur Research Foundation |
Anti-cancer activity of carvedilol and its isomers
|
SK285547B6
(sk)
*
|
2002-11-08 |
2007-03-01 |
Zentiva, A. S. |
Spôsob prípravy Carvedilolu
|
WO2004041252A1
(fr)
*
|
2002-11-08 |
2004-05-21 |
Egalet A/S |
Compositions de carvedilol a liberation commandee
|
EP1615888A1
(fr)
*
|
2003-04-21 |
2006-01-18 |
Matrix Laboratories Ltd |
Procede de fabrication de carvedilol, forme-ii
|
OA13174A
(en)
*
|
2003-05-30 |
2006-12-13 |
Ranbaxy Lab Ltd |
Substituted pyrrole derivatives and their use as HMG-Co inhibitors.
|
US7482471B2
(en)
*
|
2003-06-20 |
2009-01-27 |
Sun Pharmaceutical Industries Limited |
Process for preparation of 1-[9H-carbazol-4-yloxy]-3-[{2-(2-(-methoxy)phenoxy)-ethyl}-amino]-propan-2-ol
|
US20050037063A1
(en)
*
|
2003-07-21 |
2005-02-17 |
Bolton Anthony E. |
Combined therapies
|
JP2007512350A
(ja)
*
|
2003-11-25 |
2007-05-17 |
エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド |
カルベジロール組成物の治療および送達方法
|
US7750036B2
(en)
*
|
2003-11-25 |
2010-07-06 |
Sb Pharmco Puerto Rico Inc. |
Carvedilol salts, corresponding compositions, methods of delivery and/or treatment
|
US8734850B2
(en)
*
|
2003-11-25 |
2014-05-27 |
Flamel Technologies |
Oral medicinal product with modified release of at least one active principle in multimicrocapsular form
|
US20070191456A1
(en)
*
|
2004-04-22 |
2007-08-16 |
Tarur Venkatasubramanian R |
Novel process for the preparation of 1-(9h-carbazol-4-yloxy)-3-[[2-(-methoxyphenoxy)-ethyl] amino]-propan-2-ol
|
GB0411273D0
(en)
*
|
2004-05-20 |
2004-06-23 |
Cipla Ltd |
Process and product
|
JP2008521805A
(ja)
*
|
2004-11-30 |
2008-06-26 |
アーテシアン セラピューティクス, インコーポレイテッド |
β−アドレナリン作用性受容体およびホスホジエステラーゼに対する阻害活性を有する強心性化合物
|
PT1838670E
(pt)
*
|
2004-12-09 |
2009-12-18 |
Zach System Spa |
Processo para a preparação de carvedilol e seus enantiómeros
|
US20070027202A1
(en)
*
|
2005-06-07 |
2007-02-01 |
Ashok Kumar |
Process for the preparation of carvedilol and its salts
|
US20070043099A1
(en)
*
|
2005-06-09 |
2007-02-22 |
Igor Lifshitz |
Crystalline forms of carvedilol and processes for their preparation
|
GT200600381A
(es)
|
2005-08-25 |
2007-03-28 |
|
Compuestos organicos
|
AU2006300877A1
(en)
|
2005-10-13 |
2007-04-19 |
Orchid Research Laboratories Limited |
Heterocyclic compounds as pSTAT3/IL-6 inhibitors
|
US7741317B2
(en)
|
2005-10-21 |
2010-06-22 |
Bristol-Myers Squibb Company |
LXR modulators
|
CA2627599A1
(fr)
*
|
2005-11-08 |
2007-05-18 |
Ranbaxy Laboratories Limited |
Procede de preparation de sel hemicalcique d'acide (3r,5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxymethylphenylamino)carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoique
|
US7888376B2
(en)
|
2005-11-23 |
2011-02-15 |
Bristol-Myers Squibb Company |
Heterocyclic CETP inhibitors
|
US8367112B2
(en)
*
|
2006-02-28 |
2013-02-05 |
Alkermes Pharma Ireland Limited |
Nanoparticulate carverdilol formulations
|
WO2008020314A2
(fr)
*
|
2006-03-14 |
2008-02-21 |
Ranbaxy Laboratories Limited |
Formulations de dosage stabilisantes à base de statine
|
WO2007144785A2
(fr)
*
|
2006-03-26 |
2007-12-21 |
Uti Limited Partnership |
Inhibiteurs du récepteur de la ryanodine et procédés associés
|
EP1991527A2
(fr)
*
|
2006-06-28 |
2008-11-19 |
Teva Pharmaceutical Industries Ltd |
Formes polymorphes de carvédilol phosphate
|
JP2009543773A
(ja)
*
|
2006-07-14 |
2009-12-10 |
ランバクシー ラボラトリーズ リミテッド |
HMG−CoAレダクターゼ阻害剤の多形体及びその使用
|
WO2008038301A1
(fr)
*
|
2006-09-26 |
2008-04-03 |
Morepen Laboratories Limited |
Procédé pour la préparation de carvédilol
|
WO2008070072A2
(fr)
*
|
2006-12-01 |
2008-06-12 |
Mutual Pharmaceutical Company, Inc. |
Formes, compositions de carvédilol, et leurs procédés de préparation
|
US20090028935A1
(en)
*
|
2006-12-01 |
2009-01-29 |
Kristin Arnold |
Carvedilol forms, compositions, and methods of preparation thereof
|
ES2382009T3
(es)
|
2006-12-01 |
2012-06-04 |
Bristol-Myers Squibb Company |
Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares
|
WO2008084494A1
(fr)
*
|
2007-01-08 |
2008-07-17 |
Matrix Laboratories Limited |
Nouvelles formes polymorphes de dihydrogénophosphate de carvedilol et procédé de préparation de celles-ci
|
CA2674536C
(fr)
*
|
2007-01-16 |
2016-07-26 |
Egalet A/S |
Utilisation (i) d'un polyglycol et (ii) d'une substance medicamenteuse active dans la preparation d'une composition pharmaceutique destinee (i) a reduire le risque de liberation massive induite par l'alcool et/ou (ii) a reduire le risque de toxicomanie medicamenteuse
|
CZ302357B6
(cs)
*
|
2007-01-26 |
2011-03-30 |
Zentiva, A. S. |
Zpusob cištení Carvedilolu
|
EP2114881A1
(fr)
*
|
2007-02-26 |
2009-11-11 |
Teva Pharmaceutical Industries Ltd. |
Procédé de purification du carvédilol ou de ses sels
|
US20080249317A1
(en)
*
|
2007-04-04 |
2008-10-09 |
Apotex Inc. |
Novel amorphous form of carvedilol phosphate and processes for the preparation thereof
|
WO2008142703A1
(fr)
*
|
2007-05-17 |
2008-11-27 |
Wanbury Limited |
Nouveau procédé économique pour la production de phosphate de carvédilol
|
EP2155167A2
(fr)
|
2007-06-04 |
2010-02-24 |
Egalet A/S |
Compositions pharmaceutiques à libération contrôlée pour un effet prolongé
|
US8278461B2
(en)
*
|
2007-08-21 |
2012-10-02 |
Lupin Limited |
Stable amorphous form of carvedilol dihydrogen phosphate with stabilizer
|
WO2009035535A2
(fr)
*
|
2007-09-07 |
2009-03-19 |
Scinopharm Taiwan Ltd. |
Procédé de cristallisation de phosphate de carvédilol et produit obtenu par ce procédé
|
US20090076116A1
(en)
*
|
2007-09-13 |
2009-03-19 |
Protia, Llc |
Deuterium-enriched carvediolo
|
US20090111998A1
(en)
*
|
2007-10-25 |
2009-04-30 |
Srinivas Reddy Gade |
Process for the preparation of carvedilol dihydrogen phosphate hemihydrate and pharmaceutical compositions thereof
|
WO2009110004A1
(fr)
|
2008-03-04 |
2009-09-11 |
Lupin Limited |
Compositions pharmaceutiques stables de carvédilol
|
WO2009115906A2
(fr)
*
|
2008-03-19 |
2009-09-24 |
Cadila Pharmaceuticals Ltd. |
Procédé amélioré pour la préparation du carvédilol impliquant un dérivé d'halohydrine
|
WO2009115902A1
(fr)
*
|
2008-03-19 |
2009-09-24 |
Cadila Pharmaceuticals Ltd. |
Procédé permettant de préparer du carvedilol par protection silyle d'amine substituée
|
WO2009122425A1
(fr)
*
|
2008-04-04 |
2009-10-08 |
Shodhana Laboratories Limited |
Nouvelle forme cristalline de dihydrogénophosphate de carvédilol et procédés associés
|
US7763645B2
(en)
*
|
2008-05-23 |
2010-07-27 |
Wanbury Limited |
Carvedilol dihydrogen phosphate monohydrate
|
WO2010092589A2
(fr)
*
|
2008-05-26 |
2010-08-19 |
Alkem Laboratories Ltd. |
Procédé de préparation du phosphate de carvédilol amorphe
|
EP2393484A1
(fr)
|
2009-02-06 |
2011-12-14 |
Egalet Ltd. |
Composition à libération immédiate résistant à une maltraitance par prise d'alcool
|
AU2010265213B2
(en)
|
2009-06-24 |
2012-08-23 |
Egalet Ltd. |
Controlled release formulations
|
TWI415604B
(zh)
|
2009-09-29 |
2013-11-21 |
Tsh Biopharm Corp Ltd |
調控釋放卡菲蒂羅劑型
|
US20110229564A1
(en)
*
|
2010-03-22 |
2011-09-22 |
Amneal Pharmaceuticals, L.L.C. |
Pharmaceutical Compositions Of Carvedilol Salts And Process For Preparation Thereof
|
IN2014CN04350A
(fr)
|
2011-12-16 |
2015-09-04 |
3M Innovative Properties Co |
|
KR20150059167A
(ko)
|
2012-07-06 |
2015-05-29 |
에갈렛 리미티드 |
제어된 방출을 위한 남용 제지 약학적 조성물
|
US8492426B1
(en)
*
|
2012-07-12 |
2013-07-23 |
Anis Ahmad |
Use of carvedilol for treatment of diabetes mellitus
|
RU2618628C1
(ru)
|
2013-04-17 |
2017-05-05 |
Пфайзер Инк. |
Производные N-пиперидин-3-илбензамида для лечения сердечно-сосудистых заболеваний
|
WO2016055901A1
(fr)
|
2014-10-08 |
2016-04-14 |
Pfizer Inc. |
Composés d'amide substitué
|
US10357476B1
(en)
|
2018-10-30 |
2019-07-23 |
Anis Ahmad |
Method for treating coronary artery disease
|
EA202191892A1
(ru)
|
2019-01-18 |
2022-02-24 |
Астразенека Аб |
Ингибиторы pcsk9 и способы их применения
|
CN111170997A
(zh)
*
|
2019-12-31 |
2020-05-19 |
广州医科大学 |
咔唑类化合物及其制备方法和应用
|
CN113372260A
(zh)
*
|
2021-07-05 |
2021-09-10 |
大连蒙迪科技有限公司 |
一种卡维地洛杂质的合成方法
|