FI69468C - Foerfarande foer framstaellning av nya farmakologiskt vaerdefulla oximderivat av 3-tiadiazolyl-tiometyl-7-amino-tiazolylacetamido-cefalosporansyra - Google Patents

Foerfarande foer framstaellning av nya farmakologiskt vaerdefulla oximderivat av 3-tiadiazolyl-tiometyl-7-amino-tiazolylacetamido-cefalosporansyra Download PDF

Info

Publication number
FI69468C
FI69468C FI780444A FI780444A FI69468C FI 69468 C FI69468 C FI 69468C FI 780444 A FI780444 A FI 780444A FI 780444 A FI780444 A FI 780444A FI 69468 C FI69468 C FI 69468C
Authority
FI
Finland
Prior art keywords
formula
acid
compound
group
amino
Prior art date
Application number
FI780444A
Other languages
English (en)
Finnish (fi)
Other versions
FI780444A (fi
FI69468B (fi
Inventor
Rene Heymes
Andre Lutz
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of FI780444A publication Critical patent/FI780444A/fi
Application granted granted Critical
Publication of FI69468B publication Critical patent/FI69468B/fi
Publication of FI69468C publication Critical patent/FI69468C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI780444A 1977-02-18 1978-02-10 Foerfarande foer framstaellning av nya farmakologiskt vaerdefulla oximderivat av 3-tiadiazolyl-tiometyl-7-amino-tiazolylacetamido-cefalosporansyra FI69468C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7704745A FR2381053A1 (fr) 1977-02-18 1977-02-18 Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7704745 1977-02-18

Publications (3)

Publication Number Publication Date
FI780444A FI780444A (fi) 1978-08-19
FI69468B FI69468B (fi) 1985-10-31
FI69468C true FI69468C (fi) 1986-02-10

Family

ID=9186946

Family Applications (1)

Application Number Title Priority Date Filing Date
FI780444A FI69468C (fi) 1977-02-18 1978-02-10 Foerfarande foer framstaellning av nya farmakologiskt vaerdefulla oximderivat av 3-tiadiazolyl-tiometyl-7-amino-tiazolylacetamido-cefalosporansyra

Country Status (23)

Country Link
JP (1) JPS53108996A (fr)
AT (1) AT355722B (fr)
AU (1) AU516076B2 (fr)
BE (1) BE864074A (fr)
CA (1) CA1132537A (fr)
CH (1) CH633016A5 (fr)
DE (1) DE2806226A1 (fr)
DK (1) DK68978A (fr)
ES (2) ES467090A1 (fr)
FI (1) FI69468C (fr)
FR (1) FR2381053A1 (fr)
GB (1) GB1575180A (fr)
GR (1) GR71703B (fr)
HU (1) HU181961B (fr)
IE (1) IE46651B1 (fr)
IL (1) IL54043A (fr)
LU (1) LU79080A1 (fr)
NL (1) NL7801834A (fr)
PT (1) PT67673B (fr)
SE (1) SE434268B (fr)
SU (1) SU841590A3 (fr)
YU (1) YU41583B (fr)
ZA (1) ZA78847B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE878514A (fr) * 1978-09-04 1980-02-29 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
BE878433A (fr) * 1978-08-31 1980-02-25 Fujisawa Pharmaceutical Co Procede de preparation de derives d'acide 3-cephem-4-carboxylique 3,7-disubstitue, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
US4341775A (en) * 1978-09-11 1982-07-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE2945248A1 (de) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
US4399132A (en) * 1980-08-11 1983-08-16 American Cyanamid Company 7-Beta-[alpha-syn-methoxyimino-alpha-(2-aminothiazol-4-yl)-acetamido]-3-[(1,2,3-thiadiazol-5-ylthio)methyl]-3-cephem-4-carboxylic acid and C1 -C6 alkyl derivatives thereof
US4761409A (en) * 1984-08-16 1988-08-02 Sumitomo Pharmaceuticals Company, Limited Cephem derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins

Also Published As

Publication number Publication date
FI780444A (fi) 1978-08-19
CA1132537A (fr) 1982-09-28
HU181961B (en) 1983-11-28
SE434268B (sv) 1984-07-16
SU841590A3 (ru) 1981-06-23
JPS53108996A (en) 1978-09-22
YU33678A (en) 1983-01-21
YU41583B (en) 1987-10-31
GB1575180A (en) 1980-09-17
DK68978A (da) 1978-08-19
SE7800790L (sv) 1978-08-19
BE864074A (fr) 1978-08-17
IL54043A0 (en) 1978-04-30
AT355722B (de) 1980-03-25
FR2381053B1 (fr) 1979-06-01
ES475956A1 (es) 1979-12-16
IE780364L (en) 1978-08-18
ES467090A1 (es) 1979-06-01
NL7801834A (nl) 1978-08-22
IE46651B1 (en) 1983-08-10
GR71703B (fr) 1983-06-21
LU79080A1 (fr) 1978-09-28
FR2381053A1 (fr) 1978-09-15
ATA120978A (de) 1979-08-15
AU516076B2 (en) 1981-05-14
ZA78847B (en) 1979-03-28
IL54043A (en) 1983-02-23
CH633016A5 (en) 1982-11-15
PT67673B (fr) 1980-03-03
DE2806226A1 (de) 1978-08-24
PT67673A (fr) 1978-03-01
FI69468B (fi) 1985-10-31
AU3337578A (en) 1979-08-23

Similar Documents

Publication Publication Date Title
US4476122A (en) Alkyloximes of 7-amino-thiazolyl-acetamido-cephalosporanic acids
KR870000848B1 (ko) 세팔로스포린 유도체의 제조방법
NL192041C (nl) Geneesmiddel met antibacteriële werking, alsmede 7-£2-(2-aminothiazool-4-yl)-2-(veretherd oxyimino)-aceetamido|-3-cefem -4-carbonzuurderivaten.
JPH0794462B2 (ja) ３−アルキルオキシ又は３−アルキルチオメチル−７−アミノチアゾリルアセトアミドセファロスポラン酸の新規なオキシム誘導体、それらの製造法及びそれらを含む薬剤
US4202893A (en) Alkyloximes of 7-amino-thiazolyl-acetamido-cephalosporanic acids
DK161082B (da) Analogifremgangsmaade til fremstilling af syn-isomere oximderivater af 7-aminothiazolylacetamidocephalosporansyre
US4483855A (en) Cephalosporin derivative and antibiotic compositions
CA1093068A (fr) Traduction non-disponible
US4254119A (en) 3-Unsubstituted-3-cephem compounds
FI69468C (fi) Foerfarande foer framstaellning av nya farmakologiskt vaerdefulla oximderivat av 3-tiadiazolyl-tiometyl-7-amino-tiazolylacetamido-cefalosporansyra
FI93458C (fi) Menetelmä terapeuttisesti käyttökelpoisen 7-/2-(2-aminotiatsol-4-yyli)-2-(Z)-hydroksi-iminoasetamido/-3-(metoksimetyyli)-3-kefeemi-4-karboksyylihappo-/ -(2,2-dimetyylipropionyylioksi)etyyli/esterin diastereomeerin I valmistamiseksi
US4297352A (en) Novel oximes
DK148796B (da) Cephalosporansyrederivater til anvendelse som mellemprodukter ved fremstilling af andre cephalosporansyrederivater
JPH0246565B2 (fr)
US4097595A (en) 7-Amino-thiazolyl acetamido cephalosporanic acids
US4971962A (en) Cephalosporin compounds
HU184805B (en) Process for preparing new substituted alkyl-oximes derived from 7-/2-amino-4-thazolyl/-acetamido-cephalosporanic acid
PT92890A (pt) Processo para a preparacao de derivados de cefalosporina e de composicoes farmaceuticas que os contem
SE445350B (sv) Oximderivat av 3-azidometyl-7-amino-tiazolyl-acetamido-cefalosporansyra och dess anvendning som antibiotika
US4179502A (en) 7[2-Hydroxyiminoacetamido]cephalosporins
EP0883621A1 (fr) Derives de cephalosporines et leurs procedes de preparation
US5336776A (en) 3-acetoxymethyl-7-(iminoacetamideo)-cephalosporanic acid
KR890004694B1 (ko) 세팔로스포린 화합물 및 그의 제조 방법
KR800001595B1 (ko) 세팔로스포린 유도체의 제조방법
US4937332A (en) Cephalosporin derivatives

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: ROUSSEL UCLAF SOCIETE ANONYME