ES475956A1 - Procedimiento de preparacion de nuevas oximas derivadas del acido 3-tiadiazolil-tiometil-7-amino-tiazolil-acetamido-ce- falosporanico - Google Patents

Procedimiento de preparacion de nuevas oximas derivadas del acido 3-tiadiazolil-tiometil-7-amino-tiazolil-acetamido-ce- falosporanico

Info

Publication number
ES475956A1
ES475956A1 ES475956A ES475956A ES475956A1 ES 475956 A1 ES475956 A1 ES 475956A1 ES 475956 A ES475956 A ES 475956A ES 475956 A ES475956 A ES 475956A ES 475956 A1 ES475956 A1 ES 475956A1
Authority
ES
Spain
Prior art keywords
aminothiazolylacetamido
thiadiazolylthiomethyl
preparing
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES475956A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES475956A1 publication Critical patent/ES475956A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento de preparación de nuevas oximas derivadas del ácido 3-tiadiazolil-tiometil-7- amino-tiazolil-acetamido-cefalosporánico de fórmula IA: **fórmula** isómero sin, en la que R1 representa un átomo de hidrógeno, un grupo fácilmente eliminable por hidrólisis ácida o por hidrogenolisis, o un grupo cloroacetilo, R2 representa un radical alcohilo saturado o insaturado que tiene de 1 a 4 átomos de caarbono, R3 representa un radical alcohilo que tiene de 1 a 4 átomos de carbono o un radical alcoxi que tiene de 1 a 4 átomos de carbono, y A''1 representa un átomo de hidrógeno o un equivalente de metal alcalino, alcalino -térreo, magnesio o una base orgánica aminada.
ES475956A 1977-02-18 1978-12-13 Procedimiento de preparacion de nuevas oximas derivadas del acido 3-tiadiazolil-tiometil-7-amino-tiazolil-acetamido-ce- falosporanico Expired ES475956A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7704745A FR2381053A1 (fr) 1977-02-18 1977-02-18 Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
ES475956A1 true ES475956A1 (es) 1979-12-16

Family

ID=9186946

Family Applications (2)

Application Number Title Priority Date Filing Date
ES467090A Expired ES467090A1 (es) 1977-02-18 1978-02-17 Procedimiento de preparacion de nuevas oximas derivadas del acido 3-tiadiazolil-tiometil-7-amino-tiazolil-acetamido-ce- falosporanico
ES475956A Expired ES475956A1 (es) 1977-02-18 1978-12-13 Procedimiento de preparacion de nuevas oximas derivadas del acido 3-tiadiazolil-tiometil-7-amino-tiazolil-acetamido-ce- falosporanico

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES467090A Expired ES467090A1 (es) 1977-02-18 1978-02-17 Procedimiento de preparacion de nuevas oximas derivadas del acido 3-tiadiazolil-tiometil-7-amino-tiazolil-acetamido-ce- falosporanico

Country Status (23)

Country Link
JP (1) JPS53108996A (es)
AT (1) AT355722B (es)
AU (1) AU516076B2 (es)
BE (1) BE864074A (es)
CA (1) CA1132537A (es)
CH (1) CH633016A5 (es)
DE (1) DE2806226A1 (es)
DK (1) DK68978A (es)
ES (2) ES467090A1 (es)
FI (1) FI69468C (es)
FR (1) FR2381053A1 (es)
GB (1) GB1575180A (es)
GR (1) GR71703B (es)
HU (1) HU181961B (es)
IE (1) IE46651B1 (es)
IL (1) IL54043A (es)
LU (1) LU79080A1 (es)
NL (1) NL7801834A (es)
PT (1) PT67673B (es)
SE (1) SE434268B (es)
SU (1) SU841590A3 (es)
YU (1) YU41583B (es)
ZA (1) ZA78847B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE878514A (fr) * 1978-09-04 1980-02-29 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
BE878433A (fr) * 1978-08-31 1980-02-25 Fujisawa Pharmaceutical Co Procede de preparation de derives d'acide 3-cephem-4-carboxylique 3,7-disubstitue, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
US4341775A (en) * 1978-09-11 1982-07-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE2945248A1 (de) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
US4399132A (en) * 1980-08-11 1983-08-16 American Cyanamid Company 7-Beta-[alpha-syn-methoxyimino-alpha-(2-aminothiazol-4-yl)-acetamido]-3-[(1,2,3-thiadiazol-5-ylthio)methyl]-3-cephem-4-carboxylic acid and C1 -C6 alkyl derivatives thereof
US4761409A (en) * 1984-08-16 1988-08-02 Sumitomo Pharmaceuticals Company, Limited Cephem derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins

Also Published As

Publication number Publication date
FI780444A (fi) 1978-08-19
CA1132537A (fr) 1982-09-28
HU181961B (en) 1983-11-28
SE434268B (sv) 1984-07-16
SU841590A3 (ru) 1981-06-23
JPS53108996A (en) 1978-09-22
YU33678A (en) 1983-01-21
YU41583B (en) 1987-10-31
GB1575180A (en) 1980-09-17
DK68978A (da) 1978-08-19
SE7800790L (sv) 1978-08-19
BE864074A (fr) 1978-08-17
IL54043A0 (en) 1978-04-30
AT355722B (de) 1980-03-25
FR2381053B1 (es) 1979-06-01
FI69468C (fi) 1986-02-10
IE780364L (en) 1978-08-18
ES467090A1 (es) 1979-06-01
NL7801834A (nl) 1978-08-22
IE46651B1 (en) 1983-08-10
GR71703B (es) 1983-06-21
LU79080A1 (fr) 1978-09-28
FR2381053A1 (fr) 1978-09-15
ATA120978A (de) 1979-08-15
AU516076B2 (en) 1981-05-14
ZA78847B (en) 1979-03-28
IL54043A (en) 1983-02-23
CH633016A5 (en) 1982-11-15
PT67673B (fr) 1980-03-03
DE2806226A1 (de) 1978-08-24
PT67673A (fr) 1978-03-01
FI69468B (fi) 1985-10-31
AU3337578A (en) 1979-08-23

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010301