FI69468C - Foerfarande foer framstaellning av nya farmakologiskt vaerdefulla oximderivat av 3-tiadiazolyl-tiometyl-7-amino-tiazolylacetamido-cefalosporansyra - Google Patents
Foerfarande foer framstaellning av nya farmakologiskt vaerdefulla oximderivat av 3-tiadiazolyl-tiometyl-7-amino-tiazolylacetamido-cefalosporansyra Download PDFInfo
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- FI69468C FI69468C FI780444A FI780444A FI69468C FI 69468 C FI69468 C FI 69468C FI 780444 A FI780444 A FI 780444A FI 780444 A FI780444 A FI 780444A FI 69468 C FI69468 C FI 69468C
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- 238000000034 method Methods 0.000 title claims description 13
- 230000000144 pharmacologic effect Effects 0.000 title description 2
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- -1 2- (2-amino-4-thiazolyl) -2-methoxyiminoacetamido Chemical group 0.000 claims description 32
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- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 125000005931 tert-butyloxycarbonyl group Chemical group [H]C([H])([H])C(OC(*)=O)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 125000005270 trialkylamine group Chemical group 0.000 description 1
- LZTRCELOJRDYMQ-UHFFFAOYSA-N triphenylmethanol Chemical compound C=1C=CC=CC=1C(C=1C=CC=CC=1)(O)C1=CC=CC=C1 LZTRCELOJRDYMQ-UHFFFAOYSA-N 0.000 description 1
- JBWKIWSBJXDJDT-UHFFFAOYSA-N triphenylmethyl chloride Chemical compound C=1C=CC=CC=1C(C=1C=CC=CC=1)(Cl)C1=CC=CC=C1 JBWKIWSBJXDJDT-UHFFFAOYSA-N 0.000 description 1
- 238000002211 ultraviolet spectrum Methods 0.000 description 1
- 235000019871 vegetable fat Nutrition 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7704745A FR2381053A1 (fr) | 1977-02-18 | 1977-02-18 | Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
| FR7704745 | 1977-02-18 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI780444A7 FI780444A7 (fi) | 1978-08-19 |
| FI69468B FI69468B (fi) | 1985-10-31 |
| FI69468C true FI69468C (fi) | 1986-02-10 |
Family
ID=9186946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI780444A FI69468C (fi) | 1977-02-18 | 1978-02-10 | Foerfarande foer framstaellning av nya farmakologiskt vaerdefulla oximderivat av 3-tiadiazolyl-tiometyl-7-amino-tiazolylacetamido-cefalosporansyra |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS53108996A (de) |
| AT (1) | AT355722B (de) |
| AU (1) | AU516076B2 (de) |
| BE (1) | BE864074A (de) |
| CA (1) | CA1132537A (de) |
| CH (1) | CH633016A5 (de) |
| DE (1) | DE2806226A1 (de) |
| DK (1) | DK68978A (de) |
| ES (2) | ES467090A1 (de) |
| FI (1) | FI69468C (de) |
| FR (1) | FR2381053A1 (de) |
| GB (1) | GB1575180A (de) |
| GR (1) | GR71703B (de) |
| HU (1) | HU181961B (de) |
| IE (1) | IE46651B1 (de) |
| IL (1) | IL54043A (de) |
| LU (1) | LU79080A1 (de) |
| NL (1) | NL7801834A (de) |
| PT (1) | PT67673B (de) |
| SE (1) | SE434268B (de) |
| SU (1) | SU841590A3 (de) |
| YU (1) | YU41583B (de) |
| ZA (1) | ZA78847B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE878433A (fr) * | 1978-08-31 | 1980-02-25 | Fujisawa Pharmaceutical Co | Procede de preparation de derives d'acide 3-cephem-4-carboxylique 3,7-disubstitue, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne |
| BE878514A (fr) * | 1978-09-04 | 1980-02-29 | Fujisawa Pharmaceutical Co | Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne |
| DE2714880A1 (de) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
| US4341775A (en) * | 1978-09-11 | 1982-07-27 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
| DE2945248A1 (de) * | 1978-11-13 | 1980-05-22 | Fujisawa Pharmaceutical Co | Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel |
| CH642957A5 (de) | 1980-02-18 | 1984-05-15 | Lonza Ag | Verfahren zur herstellung von (2-aminothiazol-4-yl)-essigsaeure-hydrochlorid. |
| US4399132A (en) * | 1980-08-11 | 1983-08-16 | American Cyanamid Company | 7-Beta-[alpha-syn-methoxyimino-alpha-(2-aminothiazol-4-yl)-acetamido]-3-[(1,2,3-thiadiazol-5-ylthio)methyl]-3-cephem-4-carboxylic acid and C1 -C6 alkyl derivatives thereof |
| US4761409A (en) * | 1984-08-16 | 1988-08-02 | Sumitomo Pharmaceuticals Company, Limited | Cephem derivatives |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1399086A (en) * | 1971-05-14 | 1975-06-25 | Glaxo Lab Ltd | Cephalosporin compounds |
| DK154939C (da) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf |
| DK162391C (da) * | 1976-04-12 | 1992-03-09 | Fujisawa Pharmaceutical Co | Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser |
| DE2760484C2 (de) * | 1976-04-14 | 1992-12-03 | Takeda Chemical Industries, Ltd., Osaka, Jp |
-
1977
- 1977-02-18 FR FR7704745A patent/FR2381053A1/fr active Granted
-
1978
- 1978-01-23 SE SE7800790A patent/SE434268B/sv not_active IP Right Cessation
- 1978-02-10 FI FI780444A patent/FI69468C/fi not_active IP Right Cessation
- 1978-02-13 IL IL54043A patent/IL54043A/xx unknown
- 1978-02-13 ZA ZA00780847A patent/ZA78847B/xx unknown
- 1978-02-14 YU YU336/78A patent/YU41583B/xx unknown
- 1978-02-14 DE DE19782806226 patent/DE2806226A1/de not_active Withdrawn
- 1978-02-14 SU SU782578251A patent/SU841590A3/ru active
- 1978-02-16 DK DK68978A patent/DK68978A/da not_active Application Discontinuation
- 1978-02-16 GR GR55474A patent/GR71703B/el unknown
- 1978-02-17 BE BE185267A patent/BE864074A/xx not_active IP Right Cessation
- 1978-02-17 ES ES467090A patent/ES467090A1/es not_active Expired
- 1978-02-17 LU LU79080A patent/LU79080A1/xx unknown
- 1978-02-17 HU HU78RO963A patent/HU181961B/hu unknown
- 1978-02-17 JP JP1666578A patent/JPS53108996A/ja active Pending
- 1978-02-17 NL NL7801834A patent/NL7801834A/xx not_active Application Discontinuation
- 1978-02-17 PT PT67673A patent/PT67673B/pt unknown
- 1978-02-17 AU AU33375/78A patent/AU516076B2/en not_active Expired
- 1978-02-17 CH CH178978A patent/CH633016A5/fr not_active IP Right Cessation
- 1978-02-17 CA CA297,248A patent/CA1132537A/fr not_active Expired
- 1978-02-20 AT AT120978A patent/AT355722B/de not_active IP Right Cessation
- 1978-02-20 IE IE364/78A patent/IE46651B1/en unknown
- 1978-02-20 GB GB6621/78A patent/GB1575180A/en not_active Expired
- 1978-12-13 ES ES475956A patent/ES475956A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE864074A (fr) | 1978-08-17 |
| PT67673A (fr) | 1978-03-01 |
| SE434268B (sv) | 1984-07-16 |
| PT67673B (fr) | 1980-03-03 |
| DE2806226A1 (de) | 1978-08-24 |
| IL54043A0 (en) | 1978-04-30 |
| SE7800790L (sv) | 1978-08-19 |
| CH633016A5 (en) | 1982-11-15 |
| YU41583B (en) | 1987-10-31 |
| GB1575180A (en) | 1980-09-17 |
| HU181961B (en) | 1983-11-28 |
| ZA78847B (en) | 1979-03-28 |
| ATA120978A (de) | 1979-08-15 |
| FR2381053B1 (de) | 1979-06-01 |
| AT355722B (de) | 1980-03-25 |
| JPS53108996A (en) | 1978-09-22 |
| FR2381053A1 (fr) | 1978-09-15 |
| YU33678A (en) | 1983-01-21 |
| GR71703B (de) | 1983-06-21 |
| IE780364L (en) | 1978-08-18 |
| IE46651B1 (en) | 1983-08-10 |
| AU516076B2 (en) | 1981-05-14 |
| LU79080A1 (fr) | 1978-09-28 |
| AU3337578A (en) | 1979-08-23 |
| FI780444A7 (fi) | 1978-08-19 |
| CA1132537A (fr) | 1982-09-28 |
| ES475956A1 (es) | 1979-12-16 |
| ES467090A1 (es) | 1979-06-01 |
| NL7801834A (nl) | 1978-08-22 |
| IL54043A (en) | 1983-02-23 |
| SU841590A3 (ru) | 1981-06-23 |
| FI69468B (fi) | 1985-10-31 |
| DK68978A (da) | 1978-08-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: ROUSSEL UCLAF SOCIETE ANONYME |