FI69304C - Foerfarande foer framstaellning av beta-((2-metylpropoxi)metyl)-n-fenyl-n-(fenylmetyl)-1-pyrrolidinetanaminhydrokloridhydrat - Google Patents

Foerfarande foer framstaellning av beta-((2-metylpropoxi)metyl)-n-fenyl-n-(fenylmetyl)-1-pyrrolidinetanaminhydrokloridhydrat Download PDF

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Publication number
FI69304C
FI69304C FI833016A FI833016A FI69304C FI 69304 C FI69304 C FI 69304C FI 833016 A FI833016 A FI 833016A FI 833016 A FI833016 A FI 833016A FI 69304 C FI69304 C FI 69304C
Authority
FI
Finland
Prior art keywords
mixture
phenylmethyl
phenyl
methylpropoxy
methyl
Prior art date
Application number
FI833016A
Other languages
English (en)
Finnish (fi)
Other versions
FI833016A (fi
FI69304B (fi
FI833016A0 (fi
Inventor
Frank J Stiefel
Original Assignee
Carter Wallace
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carter Wallace filed Critical Carter Wallace
Publication of FI833016A publication Critical patent/FI833016A/fi
Publication of FI833016A0 publication Critical patent/FI833016A0/fi
Publication of FI69304B publication Critical patent/FI69304B/fi
Application granted granted Critical
Publication of FI69304C publication Critical patent/FI69304C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Thermally Insulated Containers For Foods (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI833016A 1981-12-28 1983-08-23 Foerfarande foer framstaellning av beta-((2-metylpropoxi)metyl)-n-fenyl-n-(fenylmetyl)-1-pyrrolidinetanaminhydrokloridhydrat FI69304C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33453581A 1981-12-28 1981-12-28
US33453581 1981-12-28
PCT/US1982/001754 WO1983002274A1 (en) 1981-12-28 1982-12-10 Synthesis of 1-(3-isobutoxy-2-(phenylbenzyl)-amino)-propyl-pyrrolidino hydrochloride
US8201754 1982-12-10

Publications (4)

Publication Number Publication Date
FI833016A FI833016A (fi) 1983-08-23
FI833016A0 FI833016A0 (fi) 1983-08-23
FI69304B FI69304B (fi) 1985-09-30
FI69304C true FI69304C (fi) 1986-01-10

Family

ID=23307674

Family Applications (1)

Application Number Title Priority Date Filing Date
FI833016A FI69304C (fi) 1981-12-28 1983-08-23 Foerfarande foer framstaellning av beta-((2-metylpropoxi)metyl)-n-fenyl-n-(fenylmetyl)-1-pyrrolidinetanaminhydrokloridhydrat

Country Status (18)

Country Link
US (1) US4620015A (it)
EP (1) EP0096720B1 (it)
JP (1) JPS58502209A (it)
AT (1) ATE32715T1 (it)
AU (1) AU559555B2 (it)
BR (1) BR8208033A (it)
CA (1) CA1192907A (it)
DE (1) DE3278160D1 (it)
DK (1) DK161143C (it)
ES (1) ES8402257A1 (it)
FI (1) FI69304C (it)
IE (1) IE54312B1 (it)
IL (1) IL67533A (it)
IT (1) IT1157249B (it)
NO (1) NO158059C (it)
NZ (1) NZ202857A (it)
PT (1) PT76027B (it)
WO (1) WO1983002274A1 (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8330197D0 (en) * 1983-11-11 1983-12-21 Akzo Nv Ether of n-propanolamine derivative
DE3468684D1 (de) * 1983-11-11 1988-02-18 Akzo Nv Ether of n-propanolamine derivative
DE3726632A1 (de) * 1987-08-11 1989-05-18 Boehringer Mannheim Gmbh 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE3726633A1 (de) * 1987-08-11 1989-02-23 Boehringer Mannheim Gmbh Neue 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
US4888335A (en) * 1988-07-25 1989-12-19 Mcneilab, Inc. 3-alkoxy-2-aminopropyl heterocyclic amines and their use as cardiovascular agents
US5185362A (en) * 1988-09-14 1993-02-09 Mcneilab, Inc. Diphenylamine cardiovascular agents, compositions and use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2568778A (en) * 1948-05-28 1951-09-25 Sterling Drug Inc Tertiary-aminoalkyl-alpha-arylalpha-(4-quinolyl) acetates and amides and their preparation
FR6571M (it) * 1967-08-03 1968-12-23
BE795735A (fr) * 1972-03-06 1973-06-18 Cerm Cent Europ Rech Mauvernay Nouvelles ethylenediamines substituees a activite cardiovasculaire
FR2378024A1 (fr) * 1977-01-25 1978-08-18 Cerm Cent Europ Rech Mauvernay Nouvelle propylamine substituee, obtention et application
CA1085841A (en) * 1976-05-19 1980-09-16 Jean-Marie Ferland Aryloxy proplamines, their preparation and use thereof
FR2376123A1 (fr) * 1977-01-04 1978-07-28 Esteve Intercional Sa Prod Nouveaux derives de 4-tert.butyl-3'-chlorodiphenylamine a activite anti-histaminique, et leur procede de preparation
JPS5429493A (en) * 1977-08-10 1979-03-05 Hitachi Ltd Slat type free flow conveyor

Also Published As

Publication number Publication date
FI833016A (fi) 1983-08-23
EP0096720A1 (en) 1983-12-28
IE54312B1 (en) 1989-08-16
IT1157249B (it) 1987-02-11
IE823025L (en) 1983-06-28
DE3278160D1 (en) 1988-04-07
BR8208033A (pt) 1983-11-22
NO158059C (no) 1988-07-06
IT8249760A0 (it) 1982-12-28
EP0096720A4 (en) 1984-05-29
ES518593A0 (es) 1984-02-01
FI69304B (fi) 1985-09-30
PT76027B (en) 1985-11-18
PT76027A (en) 1983-01-01
NZ202857A (en) 1986-04-11
JPS58502209A (ja) 1983-12-22
ATE32715T1 (de) 1988-03-15
FI833016A0 (fi) 1983-08-23
NO158059B (no) 1988-03-28
DK391983A (da) 1983-08-26
DK161143B (da) 1991-06-03
US4620015A (en) 1986-10-28
NO833071L (no) 1983-08-26
DK391983D0 (da) 1983-08-26
WO1983002274A1 (en) 1983-07-07
AU559555B2 (en) 1987-03-12
CA1192907A (en) 1985-09-03
DK161143C (da) 1991-11-18
IL67533A (en) 1986-03-31
EP0096720B1 (en) 1988-03-02
ES8402257A1 (es) 1984-02-01

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MM Patent lapsed

Owner name: CARTER-WALLACE, INC.