FI67844C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3,5-diamino-6-(substituerad fenyl)-1,2,4-triazinderivat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3,5-diamino-6-(substituerad fenyl)-1,2,4-triazinderivat Download PDF

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Publication number
FI67844C
FI67844C FI801758A FI801758A FI67844C FI 67844 C FI67844 C FI 67844C FI 801758 A FI801758 A FI 801758A FI 801758 A FI801758 A FI 801758A FI 67844 C FI67844 C FI 67844C
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FI
Finland
Prior art keywords
diamino
hydrogen
triazine
compound
methyl
Prior art date
Application number
FI801758A
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English (en)
Finnish (fi)
Other versions
FI801758A7 (fi
FI67844B (fi
Inventor
Martin George Baxter
Albert Reginald Elphick
Alistair Ainslie Miller
David Alan Sawyer
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10505597&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI67844(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI801758A7 publication Critical patent/FI801758A7/fi
Priority to FI840888A priority Critical patent/FI73203C/fi
Application granted granted Critical
Publication of FI67844B publication Critical patent/FI67844B/fi
Publication of FI67844C publication Critical patent/FI67844C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI801758A 1979-06-01 1980-05-30 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3,5-diamino-6-(substituerad fenyl)-1,2,4-triazinderivat FI67844C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI840888A FI73203C (fi) 1979-06-01 1984-03-06 Mellanprodukt foer anvaendning vid framstaellning av terapeutiskt anvaendbara 3,5-diamino-6-fenyl-1,2,4- triazinderivat och foerfarande foer dess framstaellning.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7919257 1979-06-01
GB7919257 1979-06-01

Publications (3)

Publication Number Publication Date
FI801758A7 FI801758A7 (fi) 1980-12-02
FI67844B FI67844B (fi) 1985-02-28
FI67844C true FI67844C (fi) 1985-06-10

Family

ID=10505597

Family Applications (1)

Application Number Title Priority Date Filing Date
FI801758A FI67844C (fi) 1979-06-01 1980-05-30 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3,5-diamino-6-(substituerad fenyl)-1,2,4-triazinderivat

Country Status (30)

Country Link
US (2) US4486354A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (2) EP0021121B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (2) JPS5625169A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR227521A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT370097B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (2) AU530999B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
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DD (1) DD151309A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK153787C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES8104993A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI67844C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GE (1) GEP19960470B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR68380B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU182086B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE49823B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL60201A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1147087B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX9202962A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY8500062A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL950007I2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ193890A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL124029B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (1) SU1055331A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
UA (1) UA5576A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU145680A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA803250B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZW (1) ZW12980A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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BE663481A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1964-05-05
BE722109A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1967-10-12 1969-04-10
GB1223491A (en) * 1967-10-13 1971-02-24 American Home Prod Guanidines
US3637688A (en) * 1970-01-09 1972-01-25 American Home Prod 6-(fluoro and trifluoromethyl phenyl)-3 5-diamino - 1 2 4 - triazines and substituted - 6 - phenylalkyl-3,5-diamino-1 2 4-triazines
US4311701A (en) * 1979-08-16 1982-01-19 Barbara Roth Treatment of convulsions with triazines

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US4486354A (en) 1984-12-04
NZ193890A (en) 1984-07-06
EP0021121B1 (en) 1983-05-11
ES491998A0 (es) 1981-05-16
US4602017A (en) 1986-07-22
IT8048848A0 (it) 1980-05-30
AU566870B2 (en) 1987-11-05
PL224633A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-02-13
ZA803250B (en) 1982-01-27
GEP19960470B (en) 1996-08-29
ZW12980A1 (en) 1982-01-06
IL60201A (en) 1984-05-31
FI801758A7 (fi) 1980-12-02
EP0021121A1 (en) 1981-01-07
AT370097B (de) 1983-02-25
MY8500062A (en) 1985-12-31
SU1055331A3 (ru) 1983-11-15
JPH0144179B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-09-26
AU5890680A (en) 1980-12-04
DK153787C (da) 1989-01-16
IE49823B1 (en) 1985-12-25
DD151309A5 (de) 1981-10-14
IE801126L (en) 1980-12-01
JPH0144706B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-09-29
PL124029B1 (en) 1982-12-31
JPS5625169A (en) 1981-03-10
CZ384891A3 (en) 1993-10-13
ES8104993A1 (es) 1981-05-16
CS234018B2 (en) 1985-03-14
BG60427B2 (bg) 1995-03-31
ATA289680A (de) 1982-07-15
HU182086B (en) 1983-12-28
UA5576A1 (uk) 1994-12-28
AR227521A1 (es) 1982-11-15
GR68380B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-12-28
DK153787B (da) 1988-09-05
EP0059987B1 (en) 1985-08-14
IL60201A0 (en) 1980-07-31
CA1112643A (en) 1981-11-17
NL950007I2 (nl) 1997-02-03
AU530999B2 (en) 1983-08-04
MX9202962A (es) 1992-07-01
NL950007I1 (nl) 1995-06-16
IT1147087B (it) 1986-11-19
JPS6133163A (ja) 1986-02-17
DK233880A (da) 1980-12-02
FI67844B (fi) 1985-02-28
EP0059987A1 (en) 1982-09-15
YU145680A (en) 1983-02-28

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