FI67545C - Foerfarande foer framstaellning av ett farmakologiskt aktivt imidazolinderivat - Google Patents
Foerfarande foer framstaellning av ett farmakologiskt aktivt imidazolinderivat Download PDFInfo
- Publication number
- FI67545C FI67545C FI822551A FI822551A FI67545C FI 67545 C FI67545 C FI 67545C FI 822551 A FI822551 A FI 822551A FI 822551 A FI822551 A FI 822551A FI 67545 C FI67545 C FI 67545C
- Authority
- FI
- Finland
- Prior art keywords
- alkyl
- formula
- hydrogen
- methyl
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8123271 | 1981-07-28 | ||
| GB8123271 | 1981-07-28 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI822551A0 FI822551A0 (fi) | 1982-07-20 |
| FI822551L FI822551L (fi) | 1983-01-29 |
| FI67545B FI67545B (fi) | 1984-12-31 |
| FI67545C true FI67545C (fi) | 1985-04-10 |
Family
ID=10523561
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI822551A FI67545C (fi) | 1981-07-28 | 1982-07-20 | Foerfarande foer framstaellning av ett farmakologiskt aktivt imidazolinderivat |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4411908A (cs) |
| EP (1) | EP0071368B1 (cs) |
| JP (1) | JPS5826884A (cs) |
| AT (1) | ATE12769T1 (cs) |
| AU (1) | AU549166B2 (cs) |
| CA (1) | CA1171864A (cs) |
| CS (1) | CS229938B2 (cs) |
| DD (1) | DD211349A5 (cs) |
| DE (1) | DE3263123D1 (cs) |
| DK (1) | DK160275C (cs) |
| ES (1) | ES8307796A1 (cs) |
| FI (1) | FI67545C (cs) |
| GR (1) | GR76210B (cs) |
| HU (1) | HU190023B (cs) |
| IE (1) | IE53389B1 (cs) |
| IL (1) | IL66353A (cs) |
| NO (1) | NO157215C (cs) |
| NZ (1) | NZ201219A (cs) |
| PH (1) | PH18878A (cs) |
| PL (1) | PL139439B1 (cs) |
| PT (1) | PT75329B (cs) |
| SU (1) | SU1204134A3 (cs) |
| ZA (1) | ZA825164B (cs) |
| ZW (1) | ZW13782A1 (cs) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2539415B1 (fr) * | 1983-01-14 | 1985-09-13 | Adir | Derives de la d-2 imidazoline, leur preparation et leur application en therapeutique |
| ATE29494T1 (de) * | 1983-08-11 | 1987-09-15 | Synthelabo | Indol-derivate, verfahren zu deren herstellung und deren therapeutische anwendung. |
| DE3471308D1 (en) * | 1983-10-17 | 1988-06-23 | Synthelabo | Imidazoline derivatives, their preparation and therapeutical use |
| FR2621486B1 (fr) * | 1987-10-07 | 1990-01-26 | Synthelabo | Utilisation de derives de pyrrolo(3,2,1-hi)indole pour obtenir un medicament destine au traitement du diabete |
| KR910005851B1 (ko) * | 1983-12-12 | 1991-08-05 | 신 떼라보 | 피롤로[3,2,1-hi]인돌유도체 및 약학적으로 허용되는 그의 산부가염을 제조하는 방법 |
| GB2167408B (en) * | 1984-11-23 | 1988-05-25 | Farmos Oy | Substituted imidazole derivatives and their preparation and use |
| ES8705871A1 (es) * | 1984-12-29 | 1987-05-16 | Kaken Pharma Co Ltd | Un procedimiento para preparar un derivado de benzofurano |
| US4895867A (en) * | 1986-06-26 | 1990-01-23 | Norwich Eaton Pharmaceuticals, Inc. | 2-(5-phenyl-2-furanyl)imidazoles useful as cardiotonic agents |
| US4882343A (en) * | 1987-08-28 | 1989-11-21 | G. D. Searle & Co. | Biarylalkylimidazole derivatives as anti-depressants |
| DK344489D0 (da) * | 1989-07-12 | 1989-07-12 | Novo Nordisk As | Substituerede 2-imidazoliner og fremstilling og anvendelse deraf |
| GB9020128D0 (en) * | 1990-09-14 | 1990-10-24 | Reckitt & Colmann Prod Ltd | Imidazoline derivatives |
| GB9127050D0 (en) * | 1991-12-20 | 1992-02-19 | Orion Yhtymae Oy | Substituted imidazole derivatives and their preparation and use |
| GB9127430D0 (en) * | 1991-12-27 | 1992-02-19 | Scras | Benzofuranylimidazole derivatives |
| FR2706303B1 (fr) * | 1993-06-18 | 1995-09-08 | Pf Medicament | Utilisation de l'Efaroxan et de ses dérivés pour la préparation d'un médicament destiné au traitement de la maladie de Parkinson. |
| FR2707166B1 (fr) * | 1993-07-09 | 1995-09-29 | Pf Medicament | Utilisation de l'efaroxan et de ses dérivés pour la fabrication de médicaments destinés au traitement de maladies neurodégénératives et leur progression . |
| PT924209E (pt) * | 1997-12-19 | 2003-08-29 | Lilly Co Eli | Compostos de imidazolina hipoglicemicos |
| FR2784989B1 (fr) * | 1998-09-10 | 2002-09-27 | Fabre Pierre Sante | Derive d'ester d'acide 2-ethyl-2,3-dihydrobenzofurane- carboxylique, procede de preparation et utilisation pour la preparation de derives de l'efaroxan |
| WO2000073269A2 (en) * | 1999-06-02 | 2000-12-07 | Regents Of The University Of Minnesota | Nicotine receptor ligands |
| SE9902267D0 (sv) * | 1999-06-16 | 1999-06-16 | Astra Ab | New compounds |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2168216A1 (en) * | 1972-01-21 | 1973-08-31 | Labaz | Substd imidazolines - with vasoconstrictor activity |
| US3927023A (en) * | 1974-05-24 | 1975-12-16 | Warner Lambert Co | Imidazolyl benzofurans |
| DE2933962A1 (de) * | 1979-08-22 | 1981-03-26 | Hoechst Ag, 65929 Frankfurt | Verfahren zur herstellung von 4,5-dichlor-imidazolen. |
-
1982
- 1982-07-09 NZ NZ201219A patent/NZ201219A/en unknown
- 1982-07-09 ZW ZW137/82A patent/ZW13782A1/xx unknown
- 1982-07-12 CA CA000407114A patent/CA1171864A/en not_active Expired
- 1982-07-13 US US06/397,686 patent/US4411908A/en not_active Expired - Lifetime
- 1982-07-14 EP EP82303709A patent/EP0071368B1/en not_active Expired
- 1982-07-14 DE DE8282303709T patent/DE3263123D1/de not_active Expired
- 1982-07-14 AT AT82303709T patent/ATE12769T1/de not_active IP Right Cessation
- 1982-07-15 GR GR68759A patent/GR76210B/el unknown
- 1982-07-19 IL IL66353A patent/IL66353A/xx not_active IP Right Cessation
- 1982-07-20 ZA ZA825164A patent/ZA825164B/xx unknown
- 1982-07-20 FI FI822551A patent/FI67545C/fi not_active IP Right Cessation
- 1982-07-26 SU SU823467047A patent/SU1204134A3/ru active
- 1982-07-26 IE IE1789/82A patent/IE53389B1/en not_active IP Right Cessation
- 1982-07-26 PL PL1982237655A patent/PL139439B1/pl unknown
- 1982-07-26 NO NO822568A patent/NO157215C/no not_active IP Right Cessation
- 1982-07-26 ES ES514359A patent/ES8307796A1/es not_active Expired
- 1982-07-27 JP JP57131075A patent/JPS5826884A/ja active Granted
- 1982-07-27 DD DD82241979A patent/DD211349A5/de unknown
- 1982-07-27 CS CS825668A patent/CS229938B2/cs unknown
- 1982-07-27 DK DK335682A patent/DK160275C/da active
- 1982-07-27 AU AU86438/82A patent/AU549166B2/en not_active Ceased
- 1982-07-27 PT PT75329A patent/PT75329B/pt unknown
- 1982-07-27 HU HU822410A patent/HU190023B/hu not_active IP Right Cessation
- 1982-07-27 PH PH27638A patent/PH18878A/en unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Transfer of assignment of patent |
Owner name: PIERRE FABRE MEDICAMENT SA |
|
| MM | Patent lapsed |
Owner name: PIERRE FABRE MEDICAMENT SA |