ZW13782A1 - Imidazoline derivatives - Google Patents

Imidazoline derivatives

Info

Publication number
ZW13782A1
ZW13782A1 ZW137/82A ZW13782A ZW13782A1 ZW 13782 A1 ZW13782 A1 ZW 13782A1 ZW 137/82 A ZW137/82 A ZW 137/82A ZW 13782 A ZW13782 A ZW 13782A ZW 13782 A1 ZW13782 A1 ZW 13782A1
Authority
ZW
Zimbabwe
Prior art keywords
hydrogen
imidazoline derivatives
bromo
fluoro
chloro
Prior art date
Application number
ZW137/82A
Other languages
English (en)
Inventor
Christopher Bourne Chapleo
Peter Leslie Myers
Original Assignee
Reckitt & Colmann Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reckitt & Colmann Prod Ltd filed Critical Reckitt & Colmann Prod Ltd
Publication of ZW13782A1 publication Critical patent/ZW13782A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
ZW137/82A 1981-07-28 1982-07-09 Imidazoline derivatives ZW13782A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8123271 1981-07-28

Publications (1)

Publication Number Publication Date
ZW13782A1 true ZW13782A1 (en) 1982-10-06

Family

ID=10523561

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW137/82A ZW13782A1 (en) 1981-07-28 1982-07-09 Imidazoline derivatives

Country Status (24)

Country Link
US (1) US4411908A (cs)
EP (1) EP0071368B1 (cs)
JP (1) JPS5826884A (cs)
AT (1) ATE12769T1 (cs)
AU (1) AU549166B2 (cs)
CA (1) CA1171864A (cs)
CS (1) CS229938B2 (cs)
DD (1) DD211349A5 (cs)
DE (1) DE3263123D1 (cs)
DK (1) DK160275C (cs)
ES (1) ES8307796A1 (cs)
FI (1) FI67545C (cs)
GR (1) GR76210B (cs)
HU (1) HU190023B (cs)
IE (1) IE53389B1 (cs)
IL (1) IL66353A (cs)
NO (1) NO157215C (cs)
NZ (1) NZ201219A (cs)
PH (1) PH18878A (cs)
PL (1) PL139439B1 (cs)
PT (1) PT75329B (cs)
SU (1) SU1204134A3 (cs)
ZA (1) ZA825164B (cs)
ZW (1) ZW13782A1 (cs)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2539415B1 (fr) * 1983-01-14 1985-09-13 Adir Derives de la d-2 imidazoline, leur preparation et leur application en therapeutique
ATE29494T1 (de) * 1983-08-11 1987-09-15 Synthelabo Indol-derivate, verfahren zu deren herstellung und deren therapeutische anwendung.
DE3471308D1 (en) * 1983-10-17 1988-06-23 Synthelabo Imidazoline derivatives, their preparation and therapeutical use
FR2621486B1 (fr) * 1987-10-07 1990-01-26 Synthelabo Utilisation de derives de pyrrolo(3,2,1-hi)indole pour obtenir un medicament destine au traitement du diabete
KR910005851B1 (ko) * 1983-12-12 1991-08-05 신 떼라보 피롤로[3,2,1-hi]인돌유도체 및 약학적으로 허용되는 그의 산부가염을 제조하는 방법
GB2167408B (en) * 1984-11-23 1988-05-25 Farmos Oy Substituted imidazole derivatives and their preparation and use
ES8705871A1 (es) * 1984-12-29 1987-05-16 Kaken Pharma Co Ltd Un procedimiento para preparar un derivado de benzofurano
US4895867A (en) * 1986-06-26 1990-01-23 Norwich Eaton Pharmaceuticals, Inc. 2-(5-phenyl-2-furanyl)imidazoles useful as cardiotonic agents
US4882343A (en) * 1987-08-28 1989-11-21 G. D. Searle & Co. Biarylalkylimidazole derivatives as anti-depressants
DK344489D0 (da) * 1989-07-12 1989-07-12 Novo Nordisk As Substituerede 2-imidazoliner og fremstilling og anvendelse deraf
GB9020128D0 (en) * 1990-09-14 1990-10-24 Reckitt & Colmann Prod Ltd Imidazoline derivatives
GB9127050D0 (en) * 1991-12-20 1992-02-19 Orion Yhtymae Oy Substituted imidazole derivatives and their preparation and use
GB9127430D0 (en) * 1991-12-27 1992-02-19 Scras Benzofuranylimidazole derivatives
FR2706303B1 (fr) * 1993-06-18 1995-09-08 Pf Medicament Utilisation de l'Efaroxan et de ses dérivés pour la préparation d'un médicament destiné au traitement de la maladie de Parkinson.
FR2707166B1 (fr) * 1993-07-09 1995-09-29 Pf Medicament Utilisation de l'efaroxan et de ses dérivés pour la fabrication de médicaments destinés au traitement de maladies neurodégénératives et leur progression .
PT924209E (pt) * 1997-12-19 2003-08-29 Lilly Co Eli Compostos de imidazolina hipoglicemicos
FR2784989B1 (fr) * 1998-09-10 2002-09-27 Fabre Pierre Sante Derive d'ester d'acide 2-ethyl-2,3-dihydrobenzofurane- carboxylique, procede de preparation et utilisation pour la preparation de derives de l'efaroxan
WO2000073269A2 (en) * 1999-06-02 2000-12-07 Regents Of The University Of Minnesota Nicotine receptor ligands
SE9902267D0 (sv) * 1999-06-16 1999-06-16 Astra Ab New compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2168216A1 (en) * 1972-01-21 1973-08-31 Labaz Substd imidazolines - with vasoconstrictor activity
US3927023A (en) * 1974-05-24 1975-12-16 Warner Lambert Co Imidazolyl benzofurans
DE2933962A1 (de) * 1979-08-22 1981-03-26 Hoechst Ag, 65929 Frankfurt Verfahren zur herstellung von 4,5-dichlor-imidazolen.

Also Published As

Publication number Publication date
IE821789L (en) 1983-01-28
IL66353A0 (en) 1982-11-30
EP0071368B1 (en) 1985-04-17
CA1171864A (en) 1984-07-31
JPS5826884A (ja) 1983-02-17
CS229938B2 (en) 1984-07-16
SU1204134A3 (ru) 1986-01-07
AU549166B2 (en) 1986-01-16
FI67545C (fi) 1985-04-10
DK160275C (da) 1991-07-22
ATE12769T1 (de) 1985-05-15
HU190023B (en) 1986-08-28
NO157215B (no) 1987-11-02
DK160275B (da) 1991-02-18
DE3263123D1 (de) 1985-05-23
NO157215C (no) 1988-02-10
US4411908A (en) 1983-10-25
IE53389B1 (en) 1988-10-26
PL139439B1 (en) 1987-01-31
DD211349A5 (de) 1984-07-11
FI822551L (fi) 1983-01-29
PL237655A1 (en) 1983-03-28
NO822568L (no) 1983-01-31
JPH0233038B2 (cs) 1990-07-25
IL66353A (en) 1985-08-30
PH18878A (en) 1985-10-22
GR76210B (cs) 1984-08-03
ES514359A0 (es) 1983-08-01
FI822551A0 (fi) 1982-07-20
DK335682A (da) 1983-01-29
NZ201219A (en) 1984-10-19
EP0071368A1 (en) 1983-02-09
ES8307796A1 (es) 1983-08-01
FI67545B (fi) 1984-12-31
PT75329A (en) 1982-08-01
PT75329B (en) 1984-07-31
ZA825164B (en) 1983-05-25
AU8643882A (en) 1983-06-02

Similar Documents

Publication Publication Date Title
IE821789L (en) Benzofuranylimidazolines
DK540485A (da) Substituerede imidazolderivater samt fremgangsmaade til fremstilling deraf og forbindelsernes anvendelse
IL71664A (en) Fluoroalkoxy compounds,process for their preparation and pharmaceutical compositions containing the same
ES8306142A1 (es) "procedimiento para la preparacion de nuevas n-(4-indolil-piperidino-alcohil)-bencimidazolonas sustituidas".
ES504206A0 (es) Procedimiento para la preparacion de nuevas 5,10-dihidro -11h-dibenzo b,e 1,4 diazepin-11-onas, sustituidas en posi- cion 5
SE8502525L (sv) 1,3-oxazolidin-2-on-derivat och forfaranden for framstellning derav
ES8400404A1 (es) Un procedimiento para la preparacion de derivados de fenilpiperidina sustituidos.
ATE15370T1 (de) 3-piperidinyl-indole derivate, ihre salze, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel und diese enthaltende arzneimittel.
ES8405394A1 (es) Un procedimiento para preparar derivados de imidazolina.
IL58999A (en) Pharmaceutical compositions comprising certain 2-(n-phenylhydroxyamino)imidazoline derivatives
JPS554392A (en) Imidazole derivative and medical composition
IL61769A0 (en) 2-phenylamino-imidazolines-(2),their preparation and pharmaceutical compositions containing them
ES515201A0 (es) "procedimiento para la fabricacion de derivados n- susbtituidos de la tetrahidroisftalimida".
TH2974EX (th) อนุพันธ์ควิโนโลนคาร์บอกซิลิคแอซิด