FI67378C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tiazolidin- och tiazanderivat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tiazolidin- och tiazanderivat Download PDF

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Publication number
FI67378C
FI67378C FI773640A FI773640A FI67378C FI 67378 C FI67378 C FI 67378C FI 773640 A FI773640 A FI 773640A FI 773640 A FI773640 A FI 773640A FI 67378 C FI67378 C FI 67378C
Authority
FI
Finland
Prior art keywords
formula
compound
acid
give
hydrogen
Prior art date
Application number
FI773640A
Other languages
English (en)
Finnish (fi)
Other versions
FI67378B (fi
FI773640A (fi
Inventor
Miguel Angel Ondetti
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of FI773640A publication Critical patent/FI773640A/fi
Application granted granted Critical
Publication of FI67378B publication Critical patent/FI67378B/fi
Publication of FI67378C publication Critical patent/FI67378C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI773640A 1976-12-03 1977-12-01 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tiazolidin- och tiazanderivat FI67378C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US74728176A 1976-12-03 1976-12-03
US74728176 1976-12-03
US83610777A 1977-09-23 1977-09-23
US83610777 1977-09-23

Publications (3)

Publication Number Publication Date
FI773640A FI773640A (fi) 1978-06-04
FI67378B FI67378B (fi) 1984-11-30
FI67378C true FI67378C (fi) 1985-03-11

Family

ID=27114718

Family Applications (1)

Application Number Title Priority Date Filing Date
FI773640A FI67378C (fi) 1976-12-03 1977-12-01 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara tiazolidin- och tiazanderivat

Country Status (28)

Country Link
JP (1) JPS5382778A (de)
AR (1) AR220689A1 (de)
AT (1) AT363467B (de)
AU (1) AU518147B2 (de)
BG (1) BG32269A3 (de)
CA (1) CA1146940A (de)
CH (1) CH634062A5 (de)
DD (1) DD133798A5 (de)
DE (1) DE2752719C2 (de)
DK (1) DK152494C (de)
EG (1) EG13037A (de)
ES (1) ES464555A1 (de)
FI (1) FI67378C (de)
FR (1) FR2372817A1 (de)
GB (1) GB1578940A (de)
GR (1) GR72453B (de)
HK (1) HK55881A (de)
IE (1) IE46169B1 (de)
IL (1) IL53352A0 (de)
IN (1) IN146945B (de)
IT (1) IT1092179B (de)
NL (3) NL171055C (de)
NO (1) NO148416C (de)
NZ (1) NZ185800A (de)
PT (1) PT67352B (de)
RO (2) RO72596A (de)
SE (1) SE441267B (de)
YU (1) YU41823B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2395998A1 (fr) * 1977-06-29 1979-01-26 Yoshitomi Pharmaceutical Nouveaux derives de la thiazolidine et leur application dans le traitement de l'hypertension
JPS5455565A (en) * 1977-10-06 1979-05-02 Santen Pharmaceut Co Ltd Novel thiazolidine derivative
JPS557255A (en) * 1978-07-03 1980-01-19 Santen Pharmaceut Co Ltd Thiazolidine derivative
AU528115B2 (en) * 1978-04-08 1983-04-14 Santen Pharmaceutical Co. Ltd. Antihypertensive 4-thiazolidine/carboxylic acids
JPS5531022A (en) * 1978-08-24 1980-03-05 Yoshitomi Pharmaceut Ind Ltd Hydroxamic acid derivative and its preparation
GR73585B (de) * 1978-09-11 1984-03-26 Univ Miami
JPS5540622A (en) * 1978-09-14 1980-03-22 Santen Pharmaceut Co Ltd Hypotensive agent
JPS5829950B2 (ja) * 1978-10-05 1983-06-25 ウェルファイド株式会社 環状イミノカルボン酸誘導体およびその塩類
JPS5562060A (en) * 1978-10-31 1980-05-10 Santen Pharmaceut Co Ltd Sulfur-containing compound
US4483861A (en) * 1978-10-31 1984-11-20 Santen Pharmaceutical Co., Ltd. Antihypertensive sulfur-containing compounds
JPS55124757A (en) * 1979-03-17 1980-09-26 Santen Pharmaceut Co Ltd Sulfur-containing compound
US4347371A (en) * 1978-12-30 1982-08-31 Santen Pharmaceutical Co., Ltd. Disulfide compounds
JPS565415A (en) * 1979-06-26 1981-01-20 Santen Pharmaceut Co Ltd Ester-type hypotensor
JPS5683483A (en) * 1979-12-13 1981-07-08 Santen Pharmaceut Co Ltd Thiazolidine compound
JPS56139455A (en) * 1980-04-02 1981-10-30 Santen Pharmaceut Co Ltd Sulfur-containing acylaminoacid
DE3152643A1 (de) * 1980-12-29 1982-12-16 Santen Pharmaceutical Co Ltd Heterocyclic 5-membered ring compounds
JPH0662529B2 (ja) * 1984-07-13 1994-08-17 三共株式会社 アミノ酸誘導体
DE3685829T2 (de) * 1985-02-04 1992-12-17 Searle & Co Heterocyclische amide.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2446100C3 (de) * 1974-09-26 1982-01-14 Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren Phenoxyalkancarbonsäureamide von Thiazolidincarbonsäuren, Verfahren zu ihrer Herstellung und Arzneimittel
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds

Also Published As

Publication number Publication date
DK538277A (da) 1978-06-04
NL8201146A (nl) 1982-07-01
JPS618834B2 (de) 1986-03-18
YU283777A (en) 1983-01-21
DK152494B (da) 1988-03-07
GR72453B (de) 1983-11-09
NO774126L (no) 1978-06-06
EG13037A (en) 1980-12-31
HK55881A (en) 1981-11-20
AR220689A1 (es) 1980-11-28
NL7713274A (nl) 1978-06-06
AU3037977A (en) 1979-05-17
BG32269A3 (en) 1982-06-15
CH634062A5 (en) 1983-01-14
DE2752719C2 (de) 1982-03-25
IL53352A0 (en) 1978-01-31
DD133798A5 (de) 1979-01-24
NL171055C (nl) 1983-02-01
PT67352B (fr) 1979-05-15
AT363467B (de) 1981-08-10
PT67352A (fr) 1978-01-01
SE441267B (sv) 1985-09-23
FR2372817A1 (fr) 1978-06-30
NO148416C (no) 1983-10-12
SE7713722L (sv) 1978-06-04
IT1092179B (it) 1985-07-06
AU518147B2 (en) 1981-09-17
ATA857677A (de) 1981-01-15
JPS5382778A (en) 1978-07-21
NL8201145A (nl) 1982-07-01
ES464555A1 (es) 1978-09-01
FI67378B (fi) 1984-11-30
YU41823B (en) 1988-02-29
DK152494C (da) 1988-07-25
GB1578940A (en) 1980-11-12
NZ185800A (en) 1980-04-28
RO78013A (ro) 1981-12-25
RO72596A (ro) 1983-08-03
IE46169L (en) 1978-06-03
CA1146940A (en) 1983-05-24
IN146945B (de) 1979-10-20
DE2752719A1 (de) 1978-06-08
FR2372817B1 (de) 1981-06-19
RO72596B (ro) 1983-07-30
IE46169B1 (en) 1983-03-09
NO148416B (no) 1983-06-27
FI773640A (fi) 1978-06-04

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MM Patent lapsed
MM Patent lapsed

Owner name: E.R. SQUIBB & SONS. INC.