FI67364C - Foerfarande foer framstaellning av en ny farmakologiskt aktiv 1-fenyl-2-(fenoxi-isopropylamino)-1,3-propandiol - Google Patents

Foerfarande foer framstaellning av en ny farmakologiskt aktiv 1-fenyl-2-(fenoxi-isopropylamino)-1,3-propandiol Download PDF

Info

Publication number
FI67364C
FI67364C FI780641A FI780641A FI67364C FI 67364 C FI67364 C FI 67364C FI 780641 A FI780641 A FI 780641A FI 780641 A FI780641 A FI 780641A FI 67364 C FI67364 C FI 67364C
Authority
FI
Finland
Prior art keywords
phenyl
propanediol
ethanol
erythro
amino
Prior art date
Application number
FI780641A
Other languages
English (en)
Finnish (fi)
Other versions
FI67364B (fi
FI780641A (fi
Inventor
Laszlo Levai
Gabor Fazekas
Lujza Petocz
Katalin Grasser
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of FI780641A publication Critical patent/FI780641A/fi
Publication of FI67364B publication Critical patent/FI67364B/fi
Application granted granted Critical
Publication of FI67364C publication Critical patent/FI67364C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/353Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00Asymmetric syntheses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/34Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/34Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
    • C07C215/361-Aryl-2-amino-1,3-propane diols
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI780641A 1977-03-11 1978-02-27 Foerfarande foer framstaellning av en ny farmakologiskt aktiv 1-fenyl-2-(fenoxi-isopropylamino)-1,3-propandiol FI67364C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUEE002484 1977-03-11
HU77EE2484A HU174125B (hu) 1977-03-11 1977-03-11 Sposob poluchenija novykh n-alkil-proizvodnykh 1-fenil-2-amino-1,3-propandiola

Publications (3)

Publication Number Publication Date
FI780641A FI780641A (fi) 1978-09-12
FI67364B FI67364B (fi) 1984-11-30
FI67364C true FI67364C (fi) 1985-03-11

Family

ID=10995716

Family Applications (1)

Application Number Title Priority Date Filing Date
FI780641A FI67364C (fi) 1977-03-11 1978-02-27 Foerfarande foer framstaellning av en ny farmakologiskt aktiv 1-fenyl-2-(fenoxi-isopropylamino)-1,3-propandiol

Country Status (23)

Country Link
US (1) US4259257A (da)
JP (1) JPS53112827A (da)
AT (1) AT355556B (da)
BE (1) BE864589A (da)
BG (1) BG28570A3 (da)
CA (1) CA1131252A (da)
CH (1) CH638172A5 (da)
CS (1) CS194840B2 (da)
DD (1) DD134868A5 (da)
DE (1) DE2810482C2 (da)
DK (1) DK144299C (da)
ES (1) ES467791A1 (da)
FI (1) FI67364C (da)
FR (1) FR2383161A1 (da)
GB (1) GB1560470A (da)
HU (1) HU174125B (da)
IL (1) IL54235A (da)
NL (1) NL7802522A (da)
PL (1) PL110231B1 (da)
SE (1) SE441825B (da)
SU (2) SU698528A3 (da)
YU (2) YU40826B (da)
ZA (1) ZA781411B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4788010A (en) * 1985-04-24 1988-11-29 E. R. Squibb & Sons, Inc. Amino substituted benzenepropanols
US5482947A (en) * 1990-11-19 1996-01-09 Talley; John J. Retroviral protease inhibitors
US7467260B2 (en) * 2004-10-08 2008-12-16 International Business Machines Corporation Method and apparatus to purge remote node cache lines to support hot node replace in a computing system

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2103266A (en) * 1933-10-07 1937-12-28 Squibb & Sons Inc Acylated diols
NL293886A (da) * 1962-06-19 1965-04-12 Merck Ag E

Also Published As

Publication number Publication date
DK108178A (da) 1978-09-12
FI67364B (fi) 1984-11-30
AT355556B (de) 1980-03-10
SU698528A3 (ru) 1979-11-15
JPS53112827A (en) 1978-10-02
DK144299B (da) 1982-02-08
DE2810482C2 (de) 1982-12-02
FR2383161B1 (da) 1981-12-04
YU40826B (en) 1986-06-30
YU40958B (en) 1986-08-31
FR2383161A1 (fr) 1978-10-06
PL110231B1 (en) 1980-07-31
CA1131252A (en) 1982-09-07
PL205230A1 (pl) 1979-03-26
JPS6256854B2 (da) 1987-11-27
IL54235A0 (en) 1978-06-15
CH638172A5 (de) 1983-09-15
ZA781411B (en) 1979-03-28
DD134868A5 (de) 1979-03-28
NL7802522A (nl) 1978-09-13
BG28570A3 (en) 1980-05-15
GB1560470A (en) 1980-02-06
IL54235A (en) 1981-01-30
FI780641A (fi) 1978-09-12
ES467791A1 (es) 1978-10-16
YU217282A (en) 1983-01-21
YU56978A (en) 1983-01-21
SE7802698L (sv) 1978-09-12
BE864589A (fr) 1978-09-06
DE2810482A1 (de) 1978-09-14
HU174125B (hu) 1979-11-28
SE441825B (sv) 1985-11-11
AU3406578A (en) 1979-09-13
ATA138378A (de) 1979-08-15
SU906366A3 (ru) 1982-02-15
CS194840B2 (en) 1979-12-31
US4259257A (en) 1981-03-31
DK144299C (da) 1982-07-12

Similar Documents

Publication Publication Date Title
EP0284621B1 (en) New psychostimulant agent
FI77018B (fi) Analogifoerfarande foer framstaellning av antidepressivt aktiv (-)-enantiomer av n-metyl-n-/3-(2-metylfenoxi) -3-fenylpropyl/amin och dess farmaceutiskt godtagbara salt.
CS208663B2 (en) Method of making the new r,s-n-/2-phenyl-2-hydroxyethyl0 -1-alkyl-3-/4-substituted phenyl/propylamines
FI67686C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara fenetanolaminderivat
GB2089338A (en) 7-Substituted benzopyranes
CS214696B2 (en) Method of making the 9-aminoalcylfluorenes
FI67364C (fi) Foerfarande foer framstaellning av en ny farmakologiskt aktiv 1-fenyl-2-(fenoxi-isopropylamino)-1,3-propandiol
FI78905B (fi) Foerfarande foer framstaellning av farmakologiskt aktiva n-/(1-etyl-2-pyrrolidinyl)metyl/bensamidderivat.
US4277501A (en) Para-nitrophenylalkylamines and pharmaceutical compositions
US4650900A (en) Aminoalkyl substituted urea derivatives and method of treatment
EP0063084B1 (fr) Dérivés de phénéthanolamine, leur préparation et leur application en thérapeutique
SK94796A3 (en) Acceptability improving method of pharmaceutically effective beta-amino acids
FI67075B (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara disubstituerade fenoletrar av 3-amino-2-hydroxipropan och salter daerav
US4331684A (en) Compounds having antidepressive activity
FI61182C (fi) Foerfarande foer framstaellning av farmaceutiskt aktiva butylaminderivat
US4026925A (en) Active derivatives of methylamine, therapeutic compositions containing the same and processes for preparing the said derivatives and compositions
AT389872B (de) Verfahren zur herstellung von neuen substituierten 2-phenylmethylen-1aminoalkyloximinocycloalkanen und deren saeureadditionssalzen
PT99050B (pt) Processo de preparacao de derivados de (2-tienil)alquilamina e de composicoes farmaceeuticas que os contem
US4336269A (en) Para-nitrophenylalkylamines
US4016284A (en) Derivatives of 1,3-benzodioxole, the preparation and use thereof
US6593340B1 (en) Pharmaceutical compositions containing N-propargylphentermine and related analogs to treat neurodegeneration and/or depression
LU82237A1 (fr) (1,1-biphenyl-2-yl)-propyl- et butylamines, leur preparatin et leur utilisation therapeutique
US4289770A (en) 2-Benzoyl-4-nitroanilides and their use as medicaments
US3988454A (en) Phenylalkylaralkylamines for pharmaceutical use
EP0048043A1 (en) Phenyl piperazine derivatives having analgetic activity

Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: E GY T GYOEGYSZERVEGYESZETI GYOER