ATA138378A - Verfahren zur herstellung von neuen optisch- aktiven threoracemischen oder erythro-1-phenyl- 2-n-alkylamino-propandiol-1,3-derivaten - Google Patents

Verfahren zur herstellung von neuen optisch- aktiven threoracemischen oder erythro-1-phenyl- 2-n-alkylamino-propandiol-1,3-derivaten

Info

Publication number
ATA138378A
ATA138378A AT138378A AT138378A ATA138378A AT A138378 A ATA138378 A AT A138378A AT 138378 A AT138378 A AT 138378A AT 138378 A AT138378 A AT 138378A AT A138378 A ATA138378 A AT A138378A
Authority
AT
Austria
Prior art keywords
threoracemic
propandiol
erythro
alkylamino
phenyl
Prior art date
Application number
AT138378A
Other languages
English (en)
Other versions
AT355556B (de
Inventor
Laszlo Ing Levai
Gabor Dr Fazekas
Lujza Dr Petoecz
Katalin Dr Grasser
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ATA138378A publication Critical patent/ATA138378A/de
Application granted granted Critical
Publication of AT355556B publication Critical patent/AT355556B/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
    • C07C215/36—1-Aryl-2-amino-1,3-propane diols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT138378A 1977-03-11 1978-02-27 Verfahren zur herstellung von neuen racemischen oder optisch aktiven threo- oder erythro-1- phenyl-2-n-alkylamino-propandiol-1,3-derivaten AT355556B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77EE2484A HU174125B (hu) 1977-03-11 1977-03-11 Sposob poluchenija novykh n-alkil-proizvodnykh 1-fenil-2-amino-1,3-propandiola

Publications (2)

Publication Number Publication Date
ATA138378A true ATA138378A (de) 1979-08-15
AT355556B AT355556B (de) 1980-03-10

Family

ID=10995716

Family Applications (1)

Application Number Title Priority Date Filing Date
AT138378A AT355556B (de) 1977-03-11 1978-02-27 Verfahren zur herstellung von neuen racemischen oder optisch aktiven threo- oder erythro-1- phenyl-2-n-alkylamino-propandiol-1,3-derivaten

Country Status (23)

Country Link
US (1) US4259257A (de)
JP (1) JPS53112827A (de)
AT (1) AT355556B (de)
BE (1) BE864589A (de)
BG (1) BG28570A3 (de)
CA (1) CA1131252A (de)
CH (1) CH638172A5 (de)
CS (1) CS194840B2 (de)
DD (1) DD134868A5 (de)
DE (1) DE2810482C2 (de)
DK (1) DK144299C (de)
ES (1) ES467791A1 (de)
FI (1) FI67364C (de)
FR (1) FR2383161A1 (de)
GB (1) GB1560470A (de)
HU (1) HU174125B (de)
IL (1) IL54235A (de)
NL (1) NL7802522A (de)
PL (1) PL110231B1 (de)
SE (1) SE441825B (de)
SU (2) SU698528A3 (de)
YU (2) YU40826B (de)
ZA (1) ZA781411B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4788010A (en) * 1985-04-24 1988-11-29 E. R. Squibb & Sons, Inc. Amino substituted benzenepropanols
US5482947A (en) * 1990-11-19 1996-01-09 Talley; John J. Retroviral protease inhibitors
US7467260B2 (en) * 2004-10-08 2008-12-16 International Business Machines Corporation Method and apparatus to purge remote node cache lines to support hot node replace in a computing system

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2103266A (en) * 1933-10-07 1937-12-28 Squibb & Sons Inc Acylated diols
NL293886A (de) * 1962-06-19 1965-04-12 Merck Ag E

Also Published As

Publication number Publication date
ZA781411B (en) 1979-03-28
JPS53112827A (en) 1978-10-02
HU174125B (hu) 1979-11-28
CS194840B2 (en) 1979-12-31
FI67364C (fi) 1985-03-11
GB1560470A (en) 1980-02-06
YU217282A (en) 1983-01-21
JPS6256854B2 (de) 1987-11-27
CA1131252A (en) 1982-09-07
FR2383161A1 (fr) 1978-10-06
DK108178A (da) 1978-09-12
US4259257A (en) 1981-03-31
DK144299C (da) 1982-07-12
SE441825B (sv) 1985-11-11
SU698528A3 (ru) 1979-11-15
YU40826B (en) 1986-06-30
DE2810482C2 (de) 1982-12-02
CH638172A5 (de) 1983-09-15
BE864589A (fr) 1978-09-06
SU906366A3 (ru) 1982-02-15
AU3406578A (en) 1979-09-13
FI67364B (fi) 1984-11-30
FR2383161B1 (de) 1981-12-04
DE2810482A1 (de) 1978-09-14
PL205230A1 (pl) 1979-03-26
DD134868A5 (de) 1979-03-28
FI780641A (fi) 1978-09-12
IL54235A (en) 1981-01-30
NL7802522A (nl) 1978-09-13
YU56978A (en) 1983-01-21
YU40958B (en) 1986-08-31
IL54235A0 (en) 1978-06-15
SE7802698L (sv) 1978-09-12
AT355556B (de) 1980-03-10
BG28570A3 (en) 1980-05-15
ES467791A1 (es) 1978-10-16
PL110231B1 (en) 1980-07-31
DK144299B (da) 1982-02-08

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
ELJ Ceased due to non-payment of the annual fee