FI66354C - Foerfarande foer framstaellning av terapeutiskt anvaendbara n-2,6-disubstituerad-fenyl)-n'-(2-imidazolidinyliden)-uread ervat - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara n-2,6-disubstituerad-fenyl)-n'-(2-imidazolidinyliden)-uread ervat Download PDF

Info

Publication number
FI66354C
FI66354C FI794036A FI794036A FI66354C FI 66354 C FI66354 C FI 66354C FI 794036 A FI794036 A FI 794036A FI 794036 A FI794036 A FI 794036A FI 66354 C FI66354 C FI 66354C
Authority
FI
Finland
Prior art keywords
urea
phenyl
imidazolidinylidene
compounds
formula
Prior art date
Application number
FI794036A
Other languages
English (en)
Finnish (fi)
Other versions
FI794036A (fi
FI66354B (fi
Inventor
Chris Royce Rasmussen
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/972,579 external-priority patent/US4229462A/en
Priority claimed from US05/972,580 external-priority patent/US4239768A/en
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of FI794036A publication Critical patent/FI794036A/fi
Publication of FI66354B publication Critical patent/FI66354B/fi
Application granted granted Critical
Publication of FI66354C publication Critical patent/FI66354C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/38—Isothioureas containing any of the groups, X being a hetero atom, Y being any atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/42—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI794036A 1978-12-22 1979-12-21 Foerfarande foer framstaellning av terapeutiskt anvaendbara n-2,6-disubstituerad-fenyl)-n'-(2-imidazolidinyliden)-uread ervat FI66354C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US05/972,579 US4229462A (en) 1978-12-22 1978-12-22 Method for controlling hypertension and compositions
US97257978 1978-12-22
US97258078 1978-12-22
US05/972,580 US4239768A (en) 1978-12-22 1978-12-22 Method for relieving irritable bowel syndrome symptoms

Publications (3)

Publication Number Publication Date
FI794036A FI794036A (fi) 1980-06-23
FI66354B FI66354B (fi) 1984-06-29
FI66354C true FI66354C (fi) 1984-10-10

Family

ID=27130555

Family Applications (1)

Application Number Title Priority Date Filing Date
FI794036A FI66354C (fi) 1978-12-22 1979-12-21 Foerfarande foer framstaellning av terapeutiskt anvaendbara n-2,6-disubstituerad-fenyl)-n'-(2-imidazolidinyliden)-uread ervat

Country Status (23)

Country Link
AT (1) AT373878B (ru)
AU (2) AU532332B2 (ru)
CA (1) CA1127651A (ru)
CH (1) CH647236A5 (ru)
DE (1) DE2951213A1 (ru)
DK (1) DK548179A (ru)
ES (1) ES487159A0 (ru)
FI (1) FI66354C (ru)
FR (2) FR2444462B1 (ru)
GB (2) GB2040681B (ru)
GR (1) GR68018B (ru)
HU (1) HU183013B (ru)
IL (1) IL59019A (ru)
IT (1) IT1126839B (ru)
NL (1) NL7909265A (ru)
NO (1) NO794249L (ru)
NZ (1) NZ192453A (ru)
PH (1) PH16571A (ru)
PT (1) PT70624A (ru)
SE (1) SE7910612L (ru)
SU (1) SU971098A3 (ru)
YU (1) YU314979A (ru)
ZW (1) ZW25379A1 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4673680A (en) * 1985-09-18 1987-06-16 Pendleton Robert G α2 -adrenergic receptor antagonists as modifiers of gastrointestinal motility
US11516649B2 (en) * 2018-10-29 2022-11-29 Apple Inc. Mechanism to activate and manage a standalone device for cellular service

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1296962A (fr) * 1960-08-05 1962-06-22 Geigy Ag J R Nouveaux composés 2-imino-1.3-di-aza et leur préparation
NL267923A (ru) * 1960-08-05

Also Published As

Publication number Publication date
FR2445321A1 (ru) 1980-07-25
AU566013B2 (en) 1987-10-08
IT1126839B (it) 1986-05-21
ES8101558A1 (es) 1980-12-16
SE7910612L (sv) 1980-06-23
NO794249L (no) 1980-06-24
PH16571A (en) 1983-11-18
DK548179A (da) 1980-06-23
FR2444462A1 (fr) 1980-07-18
IL59019A0 (en) 1980-03-31
FR2445321B1 (ru) 1983-08-26
NZ192453A (en) 1982-09-07
FI794036A (fi) 1980-06-23
ZW25379A1 (en) 1981-07-22
IT7951164A0 (it) 1979-12-21
FI66354B (fi) 1984-06-29
ATA808979A (de) 1983-07-15
GB2040681A (en) 1980-09-03
DE2951213A1 (de) 1980-07-10
SU971098A3 (ru) 1982-10-30
AT373878B (de) 1984-02-27
GB2040681B (en) 1983-04-13
CH647236A5 (de) 1985-01-15
GB2113204B (en) 1984-02-01
AU532332B2 (en) 1983-09-29
AU5378079A (en) 1980-06-26
HU183013B (en) 1984-04-28
GR68018B (ru) 1981-10-27
NL7909265A (nl) 1980-06-24
PT70624A (en) 1980-01-01
AU1640083A (en) 1983-11-17
GB2113204A (en) 1983-08-03
FR2444462B1 (fr) 1986-08-29
IL59019A (en) 1984-05-31
ES487159A0 (es) 1980-12-16
YU314979A (en) 1983-02-28
CA1127651A (en) 1982-07-13

Similar Documents

Publication Publication Date Title
KR100967070B1 (ko) 아세트산 아닐리드 유도체를 유효성분으로 하는 과활동방광 치료제
BG62023B2 (bg) Тетрахидробензтиазоли,метод за получаването и приложението им като междинни продукти или като лекарствени средства
FI90768C (fi) Menetelmä terapeuttisesti aktiivisen kinoliiniyhdisteen valmistamiseksi
JP2002507603A (ja) イミダゾロン食欲抑制薬：ｉ．非環式誘導体
EP0539153B1 (en) Acridine derivative as therapeutic agent
US3803324A (en) Amino-guanidine derivatives useful for regulating blood pressure
EA008249B1 (ru) Новые пролекарства (n-2-пиридил-n-2-гидроксикарбонилэтил)амида 1-метил-2-(4-амидинофениламинометил)бензимидазол-5-илкарбоновой кислоты, их получение и их применение в качестве лекарственных средств
US4239768A (en) Method for relieving irritable bowel syndrome symptoms
DE2916140A1 (de) 1,3-diphenyl-2-iminoimidazolidine und 1,3-diphenyl-2-iminohexahydropyrimidine, verfahren zu ihrer herstellung und solche enthaltende arzneimittel
FI66354C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara n-2,6-disubstituerad-fenyl)-n'-(2-imidazolidinyliden)-uread ervat
CZ23098A3 (cs) (R)-5-brom-N-(1-ethyl-4-methylhexahydro-1H-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridinkarboxyamid, způsob jeho přípravy a farmaceutický prostředek jej obsahující
HUT70174A (en) New 3-phenyl-sulphonyl-3,7-diazabicyclo [3.3.1] nonane compounds and pharmaceutical compounds containing the same
JP3712529B2 (ja) ３，３−ジピリジルアクリル酸アミド誘導体又はその薬学的に許容される塩
US4668683A (en) Cardiotonic quinazoline derivatives
KR100453981B1 (ko) 아미노피롤린 화합물, 이의 제조 방법 및 이를 함유하는약제 조성물
Vajragupta et al. Synthesis and antihypertensive activity of N-(alkyl/alkenyl/aryl)-N'-heterocyclic ureas and thioureas
KR830002872B1 (ko) N-아릴-n'-(2-이미다졸리딘일리덴)-우레아의 제조방법
JPH09291089A (ja) 新規な５−チアゾリルウラシル誘導体又はその塩
WO1992006080A1 (en) Antiarrhythmic agents
JP2000500455A (ja) 血液調節化合物
JPS59231057A (ja) カルボン酸アミド化合物およびその誘導体
US4298746A (en) N-(Substituted phenyl)-N'-(2-imidazolidinylidene)ureas
JPH09249661A (ja) オキシインドール誘導体
JPH0511112B2 (ru)
US4619927A (en) Novel nitropyrazinyl- and nitropyridinyl- substituted piperazin-3-one and hexahydro-1H-1,4-diazepin-5-one compounds useful as adjuncts to radiation therapy

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: MCNEILAB, INC.