FI66354C - Foerfarande foer framstaellning av terapeutiskt anvaendbara n-2,6-disubstituerad-fenyl)-n'-(2-imidazolidinyliden)-uread ervat - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara n-2,6-disubstituerad-fenyl)-n'-(2-imidazolidinyliden)-uread ervat Download PDF

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Publication number
FI66354C
FI66354C FI794036A FI794036A FI66354C FI 66354 C FI66354 C FI 66354C FI 794036 A FI794036 A FI 794036A FI 794036 A FI794036 A FI 794036A FI 66354 C FI66354 C FI 66354C
Authority
FI
Finland
Prior art keywords
urea
phenyl
imidazolidinylidene
compounds
formula
Prior art date
Application number
FI794036A
Other languages
English (en)
Finnish (fi)
Other versions
FI794036A7 (fi
FI66354B (fi
Inventor
Chris Royce Rasmussen
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/972,579 external-priority patent/US4229462A/en
Priority claimed from US05/972,580 external-priority patent/US4239768A/en
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of FI794036A7 publication Critical patent/FI794036A7/fi
Application granted granted Critical
Publication of FI66354B publication Critical patent/FI66354B/fi
Publication of FI66354C publication Critical patent/FI66354C/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30Isothioureas
    • C07C335/38Isothioureas containing any of the groups, X being a hetero atom, Y being any atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/42Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI794036A 1978-12-22 1979-12-21 Foerfarande foer framstaellning av terapeutiskt anvaendbara n-2,6-disubstituerad-fenyl)-n'-(2-imidazolidinyliden)-uread ervat FI66354C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US97258078 1978-12-22
US97257978 1978-12-22
US05/972,579 US4229462A (en) 1978-12-22 1978-12-22 Method for controlling hypertension and compositions
US05/972,580 US4239768A (en) 1978-12-22 1978-12-22 Method for relieving irritable bowel syndrome symptoms

Publications (3)

Publication Number Publication Date
FI794036A7 FI794036A7 (fi) 1980-06-23
FI66354B FI66354B (fi) 1984-06-29
FI66354C true FI66354C (fi) 1984-10-10

Family

ID=27130555

Family Applications (1)

Application Number Title Priority Date Filing Date
FI794036A FI66354C (fi) 1978-12-22 1979-12-21 Foerfarande foer framstaellning av terapeutiskt anvaendbara n-2,6-disubstituerad-fenyl)-n'-(2-imidazolidinyliden)-uread ervat

Country Status (23)

Country Link
AT (1) AT373878B (enrdf_load_stackoverflow)
AU (2) AU532332B2 (enrdf_load_stackoverflow)
CA (1) CA1127651A (enrdf_load_stackoverflow)
CH (1) CH647236A5 (enrdf_load_stackoverflow)
DE (1) DE2951213A1 (enrdf_load_stackoverflow)
DK (1) DK548179A (enrdf_load_stackoverflow)
ES (1) ES8101558A1 (enrdf_load_stackoverflow)
FI (1) FI66354C (enrdf_load_stackoverflow)
FR (2) FR2444462B1 (enrdf_load_stackoverflow)
GB (2) GB2040681B (enrdf_load_stackoverflow)
GR (1) GR68018B (enrdf_load_stackoverflow)
HU (1) HU183013B (enrdf_load_stackoverflow)
IL (1) IL59019A (enrdf_load_stackoverflow)
IT (1) IT1126839B (enrdf_load_stackoverflow)
NL (1) NL7909265A (enrdf_load_stackoverflow)
NO (1) NO794249L (enrdf_load_stackoverflow)
NZ (1) NZ192453A (enrdf_load_stackoverflow)
PH (1) PH16571A (enrdf_load_stackoverflow)
PT (1) PT70624A (enrdf_load_stackoverflow)
SE (1) SE7910612L (enrdf_load_stackoverflow)
SU (1) SU971098A3 (enrdf_load_stackoverflow)
YU (1) YU314979A (enrdf_load_stackoverflow)
ZW (1) ZW25379A1 (enrdf_load_stackoverflow)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4673680A (en) * 1985-09-18 1987-06-16 Pendleton Robert G α2 -adrenergic receptor antagonists as modifiers of gastrointestinal motility
US11516649B2 (en) 2018-10-29 2022-11-29 Apple Inc. Mechanism to activate and manage a standalone device for cellular service

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1296962A (fr) * 1960-08-05 1962-06-22 Geigy Ag J R Nouveaux composés 2-imino-1.3-di-aza et leur préparation
NL288408A (enrdf_load_stackoverflow) * 1960-08-05

Also Published As

Publication number Publication date
GB2113204B (en) 1984-02-01
FR2444462B1 (fr) 1986-08-29
ATA808979A (de) 1983-07-15
GR68018B (enrdf_load_stackoverflow) 1981-10-27
NL7909265A (nl) 1980-06-24
CA1127651A (en) 1982-07-13
FR2445321B1 (enrdf_load_stackoverflow) 1983-08-26
AU532332B2 (en) 1983-09-29
NZ192453A (en) 1982-09-07
IL59019A (en) 1984-05-31
ES487159A0 (es) 1980-12-16
AU5378079A (en) 1980-06-26
CH647236A5 (de) 1985-01-15
GB2040681B (en) 1983-04-13
ES8101558A1 (es) 1980-12-16
IT1126839B (it) 1986-05-21
DE2951213A1 (de) 1980-07-10
FI794036A7 (fi) 1980-06-23
GB2040681A (en) 1980-09-03
ZW25379A1 (en) 1981-07-22
GB2113204A (en) 1983-08-03
PT70624A (en) 1980-01-01
IL59019A0 (en) 1980-03-31
YU314979A (en) 1983-02-28
FI66354B (fi) 1984-06-29
IT7951164A0 (it) 1979-12-21
HU183013B (en) 1984-04-28
SU971098A3 (ru) 1982-10-30
DK548179A (da) 1980-06-23
PH16571A (en) 1983-11-18
SE7910612L (sv) 1980-06-23
AT373878B (de) 1984-02-27
FR2444462A1 (fr) 1980-07-18
AU566013B2 (en) 1987-10-08
NO794249L (no) 1980-06-24
AU1640083A (en) 1983-11-17
FR2445321A1 (enrdf_load_stackoverflow) 1980-07-25

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Owner name: MCNEILAB, INC.