FI65912C - Foerfarande foer framstaellning av farmaceutiskt anvaendbara inklusionskomplexer av prostacyklin och prostacyklin-c1-4-estrar med beta-cyklodextrin - Google Patents

Foerfarande foer framstaellning av farmaceutiskt anvaendbara inklusionskomplexer av prostacyklin och prostacyklin-c1-4-estrar med beta-cyklodextrin Download PDF

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Publication number
FI65912C
FI65912C FI782878A FI782878A FI65912C FI 65912 C FI65912 C FI 65912C FI 782878 A FI782878 A FI 782878A FI 782878 A FI782878 A FI 782878A FI 65912 C FI65912 C FI 65912C
Authority
FI
Finland
Prior art keywords
prostacyclin
cyclodextrin
solution
prostacyklin
complex
Prior art date
Application number
FI782878A
Other languages
English (en)
Finnish (fi)
Other versions
FI782878A (fi
FI65912B (fi
Inventor
Jozef Szejtli
Nee Rengei Magdolna Szejtli
Gyoergy Cseh
Istvan Stadler
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of FI782878A publication Critical patent/FI782878A/fi
Application granted granted Critical
Publication of FI65912B publication Critical patent/FI65912B/fi
Publication of FI65912C publication Critical patent/FI65912C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nanotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
FI782878A 1977-09-23 1978-09-21 Foerfarande foer framstaellning av farmaceutiskt anvaendbara inklusionskomplexer av prostacyklin och prostacyklin-c1-4-estrar med beta-cyklodextrin FI65912C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU77CI1770A HU179141B (fr) 1977-09-23 1977-09-23
HUCI001770 1977-09-23

Publications (3)

Publication Number Publication Date
FI782878A FI782878A (fi) 1979-03-24
FI65912B FI65912B (fi) 1984-04-30
FI65912C true FI65912C (fi) 1984-08-10

Family

ID=10994670

Family Applications (1)

Application Number Title Priority Date Filing Date
FI782878A FI65912C (fi) 1977-09-23 1978-09-21 Foerfarande foer framstaellning av farmaceutiskt anvaendbara inklusionskomplexer av prostacyklin och prostacyklin-c1-4-estrar med beta-cyklodextrin

Country Status (20)

Country Link
JP (1) JPS5456685A (fr)
AT (1) AT369362B (fr)
BE (1) BE870646A (fr)
CH (1) CH637388A5 (fr)
CS (1) CS200242B2 (fr)
DD (1) DD138600A5 (fr)
DE (1) DE2840142A1 (fr)
DK (1) DK420778A (fr)
FI (1) FI65912C (fr)
FR (1) FR2404006A1 (fr)
GB (1) GB2006193B (fr)
GR (1) GR65001B (fr)
HU (1) HU179141B (fr)
IL (1) IL55569A (fr)
IT (1) IT1160661B (fr)
NL (1) NL7809643A (fr)
PL (1) PL121664B1 (fr)
SE (1) SE447574B (fr)
SU (1) SU847914A3 (fr)
YU (1) YU220678A (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds
US4352793A (en) * 1979-04-26 1982-10-05 Sumitomo Chemical Company, Limited Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin
JPS5920230A (ja) * 1982-07-19 1984-02-01 チバ−ガイギ−・アクチエンゲゼルシヤフト ピルプロフエン含有薬剤
JPS61289034A (ja) * 1985-06-17 1986-12-19 Teijin Ltd イソカルバサイクリン類脂肪乳剤
DE3608088C2 (de) * 1986-03-07 1995-11-16 Schering Ag Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten
DE3740838A1 (de) * 1987-11-27 1989-06-08 Schering Ag Cyclodextrinclathrate von 5-cyano-prostacyclinderivaten und ihre verwendung als arzneimittel
EP1710244A4 (fr) * 2004-01-29 2009-06-17 Eisai R&D Man Co Ltd Methode de stabilisation d un compose de macrolide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS503362B1 (fr) * 1970-06-10 1975-02-04
US3953435A (en) * 1974-01-10 1976-04-27 Ono Pharmaceutical Company Aldehyde derivatives of prostaglandins
JPS5395958A (en) * 1977-01-31 1978-08-22 Ono Pharmaceut Co Ltd Prostaglandin analogues and process for their preparation
US4178367A (en) * 1977-02-21 1979-12-11 Ono Pharmaceutical Co. Ltd. Prostaglandin I2 analogues
JPS53136513A (en) * 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds

Also Published As

Publication number Publication date
GB2006193A (en) 1979-05-02
CH637388A5 (de) 1983-07-29
FI782878A (fi) 1979-03-24
IL55569A (en) 1981-12-31
PL209773A1 (pl) 1979-06-04
IL55569A0 (en) 1978-12-17
SU847914A3 (ru) 1981-07-15
NL7809643A (nl) 1979-03-27
PL121664B1 (en) 1982-05-31
DE2840142A1 (de) 1979-04-05
JPS5456685A (en) 1979-05-07
CS200242B2 (en) 1980-08-29
YU220678A (en) 1983-10-31
HU179141B (fr) 1982-08-28
SE7809946L (sv) 1979-03-24
AT369362B (de) 1982-12-27
BE870646A (fr) 1979-01-15
IT1160661B (it) 1987-03-11
FR2404006A1 (fr) 1979-04-20
GR65001B (en) 1980-06-12
ATA677478A (de) 1982-05-15
FI65912B (fi) 1984-04-30
IT7869160A0 (it) 1978-09-19
DD138600A5 (de) 1979-11-14
SE447574B (sv) 1986-11-24
GB2006193B (en) 1982-05-26
DK420778A (da) 1979-03-24
FR2404006B1 (fr) 1981-07-31

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Legal Events

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MM Patent lapsed

Owner name: CHINOIN GYOGUSZER ES VEGYESZETI TERMEKEK