FI64352C - Foerfarande foer framstaellning av terapeutiskt anvaendbara 5-ndo-(3-indolkarbonyloxi)-n-(amino(laegre)alkyl)bicyklo-(2 .21)heptan-2,3-di-endokarboxylsyraimider - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara 5-ndo-(3-indolkarbonyloxi)-n-(amino(laegre)alkyl)bicyklo-(2 .21)heptan-2,3-di-endokarboxylsyraimider Download PDF

Info

Publication number
FI64352C
FI64352C FI752572A FI752572A FI64352C FI 64352 C FI64352 C FI 64352C FI 752572 A FI752572 A FI 752572A FI 752572 A FI752572 A FI 752572A FI 64352 C FI64352 C FI 64352C
Authority
FI
Finland
Prior art keywords
endo
formula
compound
bicyclo
heptane
Prior art date
Application number
FI752572A
Other languages
English (en)
Finnish (fi)
Other versions
FI752572A (no
FI64352B (fi
Inventor
Ronald Leslie Buchanan
Alex Michael Jelenevsky
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI752572A publication Critical patent/FI752572A/fi
Application granted granted Critical
Publication of FI64352B publication Critical patent/FI64352B/fi
Publication of FI64352C publication Critical patent/FI64352C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI752572A 1974-09-18 1975-09-15 Foerfarande foer framstaellning av terapeutiskt anvaendbara 5-ndo-(3-indolkarbonyloxi)-n-(amino(laegre)alkyl)bicyklo-(2 .21)heptan-2,3-di-endokarboxylsyraimider FI64352C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US50702974A 1974-09-18 1974-09-18
US50702974 1974-09-18
US59491875 1975-07-10
US05/594,918 US3980668A (en) 1974-09-18 1975-07-10 Anti-arrhythimic 5-endo-(3-indolecarbonyloxy)-N-[amino-(lower)alkyl]bicyclo[2,2,1]heptane-2,3-di-endo-carboxylic acid imides

Publications (3)

Publication Number Publication Date
FI752572A FI752572A (no) 1976-03-19
FI64352B FI64352B (fi) 1983-07-29
FI64352C true FI64352C (fi) 1983-11-10

Family

ID=27055675

Family Applications (1)

Application Number Title Priority Date Filing Date
FI752572A FI64352C (fi) 1974-09-18 1975-09-15 Foerfarande foer framstaellning av terapeutiskt anvaendbara 5-ndo-(3-indolkarbonyloxi)-n-(amino(laegre)alkyl)bicyklo-(2 .21)heptan-2,3-di-endokarboxylsyraimider

Country Status (24)

Country Link
US (1) US3980668A (no)
JP (1) JPS6039669B2 (no)
AR (1) AR212235A1 (no)
AT (1) AT345275B (no)
CA (1) CA1068281A (no)
CH (1) CH615925A5 (no)
CS (1) CS187489B2 (no)
DD (1) DD123092A5 (no)
DE (1) DE2541434A1 (no)
DK (1) DK418075A (no)
ES (2) ES441038A1 (no)
FI (1) FI64352C (no)
FR (1) FR2313047A1 (no)
GB (1) GB1484214A (no)
HU (1) HU173807B (no)
IE (1) IE42051B1 (no)
IL (1) IL48096A (no)
LU (1) LU73418A1 (no)
NL (1) NL7510934A (no)
NO (1) NO144072C (no)
PH (1) PH11498A (no)
PL (2) PL101454B1 (no)
SE (1) SE421421B (no)
YU (2) YU40123B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2557341A1 (de) * 1975-12-19 1977-06-30 Hoechst Ag Basisch substituierte indolderivate und verfahren zu ihrer herstellung
US4139533A (en) * 1976-08-19 1979-02-13 Bristol-Myers Company Bicyclo[2,2,1]heptane-2,3-diendo carboxylic acid imide esters of quinoline carboxylic acid
GB8814277D0 (en) * 1988-06-16 1988-07-20 Glaxo Group Ltd Chemical compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3850921A (en) * 1972-09-20 1974-11-26 I Matuo Derivatives of 2,3-norbornanedicarboxamide

Also Published As

Publication number Publication date
YU40123B (en) 1985-08-31
YU284082A (en) 1985-04-30
IL48096A (en) 1979-09-30
NO144072B (no) 1981-03-09
ES441038A1 (es) 1977-07-01
LU73418A1 (no) 1976-08-13
PL101454B1 (pl) 1978-12-30
NL7510934A (nl) 1976-03-22
SE7510362L (sv) 1976-03-19
IL48096A0 (en) 1975-11-25
AR212235A1 (es) 1978-06-15
CH615925A5 (no) 1980-02-29
ES455938A1 (es) 1978-02-01
IE42051B1 (en) 1980-05-21
GB1484214A (en) 1977-09-01
CS187489B2 (en) 1979-01-31
HU173807B (no) 1979-08-28
DD123092A5 (no) 1976-11-20
US3980668A (en) 1976-09-14
ATA718575A (de) 1978-01-15
FI752572A (no) 1976-03-19
NO144072C (no) 1981-06-17
CA1068281A (en) 1979-12-18
PH11498A (en) 1978-02-01
NO753128L (no) 1976-03-19
DK418075A (da) 1976-03-19
FR2313047B1 (no) 1979-09-14
IE42051L (en) 1976-03-18
JPS51131871A (en) 1976-11-16
YU225375A (en) 1983-12-31
AU8459775A (en) 1977-03-10
DE2541434A1 (de) 1976-04-08
AT345275B (de) 1978-09-11
JPS6039669B2 (ja) 1985-09-06
SE421421B (sv) 1981-12-21
FR2313047A1 (fr) 1976-12-31
FI64352B (fi) 1983-07-29
PL100522B1 (pl) 1978-10-31

Similar Documents

Publication Publication Date Title
US4443475A (en) Amides of acyl-carnitines, process for preparing same and pharmaceutical compositions containing such amides
DE3004370C2 (no)
EP0084164B1 (de) Neue Derivate bicyclischer Aminosäuren, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung sowie neue bicyclische Aminosäuren als Zwischenstufen und Verfahren zu deren Herstellung
USRE30577E (en) Ether of n-propanol amine
DE3418270A1 (de) Neue aminotetralinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
EP0555824A1 (de) N-alpha-arylsulfonylierte Benzimidazolyl-alaninamid Derivate, diese enthaltende Arzneimittel sowie Verfahren zu ihrer Herstellung
DD270911A5 (de) Verfahren zur herstellung von neuen heteroaromatischen aminderivaten
FI64352C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 5-ndo-(3-indolkarbonyloxi)-n-(amino(laegre)alkyl)bicyklo-(2 .21)heptan-2,3-di-endokarboxylsyraimider
US3850921A (en) Derivatives of 2,3-norbornanedicarboxamide
Carabateas et al. Analgesic Antagonists. I. 4-Substituted 1-Acyl-2, 3, 4, 5-tetrahydro-1H-1, 4-benzodiazepines
EP0326106B1 (en) Alkylene diamines
US4018767A (en) Anti-arrhythmic agents
RO104347B1 (en) Production method of amids acids cyclomethylen - 1,2 - dicarboxylic
US4123440A (en) Bicyclo [2.2.1]-heptane-2,3,di-endo-carboxylic acid imide esters
EP0562440A1 (en) Imidazopyridazines as antiasthmatics
DD229699A5 (de) Verfahren zur herstellung von neuen indolderivaten
DE3120910A1 (de) Ester von alkoxy-acylderivaten des carnitins, verfahren zu deren herstellung und arzneimittel
EP0498830B1 (en) Glutamic and aspartic acid derivatives with antigastrin activity and a method for their preparation
DE60015997T2 (de) Indoloazepine als vasopressin rezeptor antagonisten
FI74456C (fi) Foerfarande foer framstaellning av terapeutiskt aktiva cystinderivat.
FI59089C (fi) Foerfarande foer framstaellning av 5-endobensoyloxi-n-(amino-(laegre)alkyl)bicyklo(2,2,1)heptan-2,3-di-endokarboxylsyraimider motverkande oregelbunden hjaertverksamhet
JPS6030670B2 (ja) 不整脈治療に有用な新規化合物
DE19616509A1 (de) Neue spezifische Immunophilin-Liganden als Antiasthmatika, Immunsuppressiva
AT244987B (de) Verfahren zur Herstellung neuer Indolylalkylguanidin-Derivate
WO2004000806A1 (de) Amide cyclischer aminosäuren als pde 4 inhibitoren

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: BRISTOL-MYERS CO