FI63422C - Analogifoerfarande foer framstaellande av nya 21-salicylsyraestrar och 21-acetylsalicylsyraestrar av steroider ur pregnanserien - Google Patents

Analogifoerfarande foer framstaellande av nya 21-salicylsyraestrar och 21-acetylsalicylsyraestrar av steroider ur pregnanserien Download PDF

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Publication number
FI63422C
FI63422C FI773929A FI773929A FI63422C FI 63422 C FI63422 C FI 63422C FI 773929 A FI773929 A FI 773929A FI 773929 A FI773929 A FI 773929A FI 63422 C FI63422 C FI 63422C
Authority
FI
Finland
Prior art keywords
salicylate
hydrogen
fluoroprednisolone
general formula
methyl
Prior art date
Application number
FI773929A
Other languages
English (en)
Finnish (fi)
Other versions
FI773929A (fi
FI63422B (fi
Inventor
Albert Meli
Gaetano Palladino
Col Marco Da
Pier Paolo Gastelli
Original Assignee
Menarini Sas
Lark Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Sas, Lark Spa filed Critical Menarini Sas
Publication of FI773929A publication Critical patent/FI773929A/fi
Publication of FI63422B publication Critical patent/FI63422B/fi
Application granted granted Critical
Publication of FI63422C publication Critical patent/FI63422C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
FI773929A 1976-12-31 1977-12-27 Analogifoerfarande foer framstaellande av nya 21-salicylsyraestrar och 21-acetylsalicylsyraestrar av steroider ur pregnanserien FI63422C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB5451076 1976-12-31
GB54510/76A GB1593978A (en) 1976-12-31 1976-12-31 Anti-inflammatory steroids

Publications (3)

Publication Number Publication Date
FI773929A FI773929A (fi) 1978-07-01
FI63422B FI63422B (fi) 1983-02-28
FI63422C true FI63422C (fi) 1983-06-10

Family

ID=10471258

Family Applications (1)

Application Number Title Priority Date Filing Date
FI773929A FI63422C (fi) 1976-12-31 1977-12-27 Analogifoerfarande foer framstaellande av nya 21-salicylsyraestrar och 21-acetylsalicylsyraestrar av steroider ur pregnanserien

Country Status (10)

Country Link
JP (1) JPS53144561A (de)
BE (1) BE862507A (de)
CH (1) CH633301A5 (de)
DK (1) DK155673C (de)
FI (1) FI63422C (de)
FR (1) FR2376160A1 (de)
GB (1) GB1593978A (de)
NL (1) NL7714482A (de)
NO (1) NO148491C (de)
SE (1) SE430607B (de)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1440063A (en) * 1972-08-11 1976-06-23 Glaxo Lab Ltd 17alpha-esters of 17alpha,21-dihydroxy-20-oxo-steroids

Also Published As

Publication number Publication date
SE7714976L (sv) 1978-07-02
FR2376160B1 (de) 1980-11-14
JPS6220197B2 (de) 1987-05-06
CH633301A5 (en) 1982-11-30
FI773929A (fi) 1978-07-01
BE862507A (fr) 1978-04-14
FI63422B (fi) 1983-02-28
DK155673B (da) 1989-05-01
NO148491C (no) 1983-10-19
NO148491B (no) 1983-07-11
JPS53144561A (en) 1978-12-15
FR2376160A1 (fr) 1978-07-28
NL7714482A (nl) 1978-07-04
DK581677A (da) 1978-07-01
SE430607B (sv) 1983-11-28
GB1593978A (en) 1981-07-22
DK155673C (da) 1989-09-04
NO774525L (no) 1978-07-03

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: A. MENARINI S.A.S.

Owner name: LARK S.P.A.