FI61789C - Foerfarande foer framstaellning av zinkbacitracinkomposition som anvaendes i djurfoder - Google Patents
Foerfarande foer framstaellning av zinkbacitracinkomposition som anvaendes i djurfoder Download PDFInfo
- Publication number
- FI61789C FI61789C FI772951A FI772951A FI61789C FI 61789 C FI61789 C FI 61789C FI 772951 A FI772951 A FI 772951A FI 772951 A FI772951 A FI 772951A FI 61789 C FI61789 C FI 61789C
- Authority
- FI
- Finland
- Prior art keywords
- bacitracin
- zinc
- weight
- carrier
- particles
- Prior art date
Links
- 108010001478 Bacitracin Proteins 0.000 claims description 86
- UCRLQOPRDMGYOA-DFTDUNEMSA-L zinc;(4r)-4-[[(2s)-2-[[(4r)-2-[(1s,2s)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2s,3s)-1-[[(3s,6r,9s,12r,15s,18r,21s)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2s)-butan-2-yl]-6-(carbox Chemical compound [Zn+2].C1SC([C@@H](N)[C@@H](C)CC)=N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC([O-])=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]1C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2NC=NC=2)C(=O)N[C@H](CC([O-])=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC1 UCRLQOPRDMGYOA-DFTDUNEMSA-L 0.000 claims description 58
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 34
- 239000000203 mixture Substances 0.000 claims description 34
- 229960003071 bacitracin Drugs 0.000 claims description 28
- 229930184125 bacitracin Natural products 0.000 claims description 28
- 241001465754 Metazoa Species 0.000 claims description 26
- CLKOFPXJLQSYAH-ABRJDSQDSA-N bacitracin A Chemical compound C1SC([C@@H](N)[C@@H](C)CC)=N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]1C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2N=CNC=2)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC1 CLKOFPXJLQSYAH-ABRJDSQDSA-N 0.000 claims description 26
- 239000011701 zinc Substances 0.000 claims description 24
- 238000000855 fermentation Methods 0.000 claims description 21
- 230000004151 fermentation Effects 0.000 claims description 21
- 238000000034 method Methods 0.000 claims description 21
- 239000002245 particle Substances 0.000 claims description 19
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 239000002002 slurry Substances 0.000 claims description 9
- 238000001694 spray drying Methods 0.000 claims description 9
- 239000012798 spherical particle Substances 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229960005364 bacitracin zinc Drugs 0.000 description 19
- 239000000047 product Substances 0.000 description 19
- 235000010216 calcium carbonate Nutrition 0.000 description 16
- 238000002474 experimental method Methods 0.000 description 15
- 229910052725 zinc Inorganic materials 0.000 description 11
- 238000001035 drying Methods 0.000 description 10
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 description 10
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 9
- 240000008042 Zea mays Species 0.000 description 8
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 8
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 8
- 235000005822 corn Nutrition 0.000 description 8
- 238000004458 analytical method Methods 0.000 description 6
- 235000013312 flour Nutrition 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- 239000003674 animal food additive Substances 0.000 description 5
- 239000012141 concentrate Substances 0.000 description 5
- 239000007787 solid Substances 0.000 description 5
- 239000011592 zinc chloride Substances 0.000 description 5
- 235000005074 zinc chloride Nutrition 0.000 description 5
- 238000001704 evaporation Methods 0.000 description 4
- 230000008020 evaporation Effects 0.000 description 4
- 229910052500 inorganic mineral Inorganic materials 0.000 description 4
- 239000002609 medium Substances 0.000 description 4
- 235000010755 mineral Nutrition 0.000 description 4
- 239000011707 mineral Substances 0.000 description 4
- 235000018102 proteins Nutrition 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 239000007921 spray Substances 0.000 description 4
- 150000003751 zinc Chemical class 0.000 description 4
- 241000283690 Bos taurus Species 0.000 description 3
- 108010068370 Glutens Proteins 0.000 description 3
- 241000282887 Suidae Species 0.000 description 3
- 238000013019 agitation Methods 0.000 description 3
- 239000000969 carrier Substances 0.000 description 3
- 230000015556 catabolic process Effects 0.000 description 3
- 238000006731 degradation reaction Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000003925 fat Substances 0.000 description 3
- 235000021312 gluten Nutrition 0.000 description 3
- 244000144977 poultry Species 0.000 description 3
- 108090000765 processed proteins & peptides Proteins 0.000 description 3
- 102000004196 processed proteins & peptides Human genes 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 241000193830 Bacillus <bacterium> Species 0.000 description 2
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 2
- 241000219745 Lupinus Species 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 235000011941 Tilia x europaea Nutrition 0.000 description 2
- 235000019742 Vitamins premix Nutrition 0.000 description 2
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 239000013256 coordination polymer Substances 0.000 description 2
- 239000003085 diluting agent Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 239000008240 homogeneous mixture Substances 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 239000004571 lime Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 238000005453 pelletization Methods 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- -1 zinc cations Chemical class 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 229910018072 Al 2 O 3 Inorganic materials 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 101500021169 Aplysia californica Myomodulin-G Proteins 0.000 description 1
- 102000011045 Chloride Channels Human genes 0.000 description 1
- 108010062745 Chloride Channels Proteins 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- 235000019733 Fish meal Nutrition 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 240000005979 Hordeum vulgare Species 0.000 description 1
- 235000007340 Hordeum vulgare Nutrition 0.000 description 1
- 240000003183 Manihot esculenta Species 0.000 description 1
- 235000016735 Manihot esculenta subsp esculenta Nutrition 0.000 description 1
- 235000019735 Meat-and-bone meal Nutrition 0.000 description 1
- 229910004298 SiO 2 Inorganic materials 0.000 description 1
- 241000209140 Triticum Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- ZOIORXHNWRGPMV-UHFFFAOYSA-N acetic acid;zinc Chemical compound [Zn].CC(O)=O.CC(O)=O ZOIORXHNWRGPMV-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- ZFXVRMSLJDYJCH-UHFFFAOYSA-N calcium magnesium Chemical compound [Mg].[Ca] ZFXVRMSLJDYJCH-UHFFFAOYSA-N 0.000 description 1
- 239000000378 calcium silicate Substances 0.000 description 1
- 229910052918 calcium silicate Inorganic materials 0.000 description 1
- OYACROKNLOSFPA-UHFFFAOYSA-N calcium;dioxido(oxo)silane Chemical compound [Ca+2].[O-][Si]([O-])=O OYACROKNLOSFPA-UHFFFAOYSA-N 0.000 description 1
- 239000008139 complexing agent Substances 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 235000012343 cottonseed oil Nutrition 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 239000008121 dextrose Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 239000006052 feed supplement Substances 0.000 description 1
- 239000004467 fishmeal Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 239000007952 growth promoter Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000007970 homogeneous dispersion Substances 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 239000002054 inoculum Substances 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 229920005610 lignin Polymers 0.000 description 1
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 description 1
- 239000001095 magnesium carbonate Substances 0.000 description 1
- 229910000021 magnesium carbonate Inorganic materials 0.000 description 1
- 235000014380 magnesium carbonate Nutrition 0.000 description 1
- 239000000391 magnesium silicate Substances 0.000 description 1
- 235000012243 magnesium silicates Nutrition 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- 238000010979 pH adjustment Methods 0.000 description 1
- 230000002688 persistence Effects 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000005979 thermal decomposition reaction Methods 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000015099 wheat brans Nutrition 0.000 description 1
- 239000004246 zinc acetate Substances 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 1
- 229960001763 zinc sulfate Drugs 0.000 description 1
- 229910000368 zinc sulfate Inorganic materials 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/585—Calcitonins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/24—Compounds of alkaline earth metals, e.g. magnesium
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Birds (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Inorganic Chemistry (AREA)
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Feed For Specific Animals (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/730,092 US4096246A (en) | 1976-10-06 | 1976-10-06 | Zinc bacitracin composition for use as a feed supplement and method for making the same |
| US73009276 | 1976-10-06 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI772951A7 FI772951A7 (fi) | 1978-04-07 |
| FI61789B FI61789B (fi) | 1982-06-30 |
| FI61789C true FI61789C (fi) | 1982-10-11 |
Family
ID=24933869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI772951A FI61789C (fi) | 1976-10-06 | 1977-10-06 | Foerfarande foer framstaellning av zinkbacitracinkomposition som anvaendes i djurfoder |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4096246A (cs) |
| JP (1) | JPS5362679A (cs) |
| AR (1) | AR216489A1 (cs) |
| AU (1) | AU512180B2 (cs) |
| BE (1) | BE859438A (cs) |
| CA (1) | CA1099640A (cs) |
| CS (1) | CS196391B2 (cs) |
| DE (1) | DE2745035A1 (cs) |
| DK (1) | DK147651C (cs) |
| ES (1) | ES462923A1 (cs) |
| FI (1) | FI61789C (cs) |
| FR (1) | FR2366800A1 (cs) |
| GB (1) | GB1575126A (cs) |
| HU (1) | HU178419B (cs) |
| IE (1) | IE45708B1 (cs) |
| IL (1) | IL53066A (cs) |
| IT (1) | IT1088851B (cs) |
| LU (1) | LU78264A1 (cs) |
| MX (1) | MX4733E (cs) |
| NL (1) | NL7710984A (cs) |
| NO (1) | NO144815C (cs) |
| PL (1) | PL104611B1 (cs) |
| SE (1) | SE425046B (cs) |
| YU (1) | YU41570B (cs) |
| ZA (1) | ZA775986B (cs) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4164572A (en) * | 1976-10-06 | 1979-08-14 | A/S Apothekernes Laboratorium For Specialpraeparater | Zinc bacitracin composition for use as a feed supplement and method for making the same |
| DE3422782A1 (de) * | 1984-06-20 | 1986-01-02 | Boehringer Ingelheim Vetmedica GmbH, 6507 Ingelheim | Zinkbacitracin enthaltender futtermittelzusatz |
| DE3725946A1 (de) * | 1987-08-05 | 1989-02-16 | Boehringer Ingelheim Vetmed | Stabilisierter futtermittelzusatz und verfahren zu seiner herstellung |
| US5958458A (en) * | 1994-06-15 | 1999-09-28 | Dumex-Alpharma A/S | Pharmaceutical multiple unit particulate formulation in the form of coated cores |
| DK0765157T3 (da) * | 1994-06-15 | 1999-10-25 | Dumex Ltd As | Pellets |
| CN106359898A (zh) * | 2016-08-30 | 2017-02-01 | 齐鲁制药（内蒙古）有限公司 | 一种杆菌肽锌预混剂的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2739063A (en) * | 1951-08-29 | 1956-03-20 | Commercial Solvents Corp | Bacitracin feed supplements from crude fermentation liquors |
| US2809892A (en) * | 1954-11-01 | 1957-10-15 | Commerical Solvents Corp | Zinc bacitracin feed supplement |
| US3019109A (en) * | 1960-05-10 | 1962-01-30 | American Cyanamid Co | Stabilization of antibiotics in feeds and feed supplements |
| US3116207A (en) * | 1961-06-07 | 1963-12-31 | Commercial Solvents Corp | Process for the protection of textiles |
| US3345178A (en) * | 1963-10-18 | 1967-10-03 | Dawe S Lab Inc | Precipitation of bacitracin upon an inert, insoluble, inorganic support for use in animal feeds |
| GB1182759A (en) * | 1967-06-21 | 1970-03-04 | Commercial Solvents Corp | Improvements in or relating to the production of Mixtures of Cycloserine and O-Carbamyl-D-Serine |
| GB1209634A (en) * | 1967-06-29 | 1970-10-21 | Rit Rech Ind Therapeut | Stabilized antibiotic compositions for animal feeding and process for preparing them |
-
1976
- 1976-10-06 US US05/730,092 patent/US4096246A/en not_active Expired - Lifetime
-
1977
- 1977-10-05 DK DK440277A patent/DK147651C/da not_active IP Right Cessation
- 1977-10-05 IT IT28303/77A patent/IT1088851B/it active
- 1977-10-05 MX MX776457U patent/MX4733E/es unknown
- 1977-10-05 NO NO773397A patent/NO144815C/no unknown
- 1977-10-05 YU YU2382/77A patent/YU41570B/xx unknown
- 1977-10-05 GB GB41476/77A patent/GB1575126A/en not_active Expired
- 1977-10-05 CA CA288,187A patent/CA1099640A/en not_active Expired
- 1977-10-05 SE SE7711158A patent/SE425046B/xx not_active IP Right Cessation
- 1977-10-05 FR FR7729965A patent/FR2366800A1/fr active Granted
- 1977-10-05 ES ES462923A patent/ES462923A1/es not_active Expired
- 1977-10-05 CS CS776451A patent/CS196391B2/cs unknown
- 1977-10-06 IL IL53066A patent/IL53066A/xx unknown
- 1977-10-06 DE DE19772745035 patent/DE2745035A1/de not_active Withdrawn
- 1977-10-06 JP JP11954877A patent/JPS5362679A/ja active Pending
- 1977-10-06 AR AR269481A patent/AR216489A1/es active
- 1977-10-06 LU LU78264A patent/LU78264A1/xx unknown
- 1977-10-06 FI FI772951A patent/FI61789C/fi not_active IP Right Cessation
- 1977-10-06 ZA ZA00775986A patent/ZA775986B/xx unknown
- 1977-10-06 BE BE181502A patent/BE859438A/xx not_active IP Right Cessation
- 1977-10-06 NL NL7710984A patent/NL7710984A/xx not_active Application Discontinuation
- 1977-10-06 AU AU29418/77A patent/AU512180B2/en not_active Expired
- 1977-10-06 HU HU77AO453A patent/HU178419B/hu unknown
- 1977-10-06 PL PL1977201332A patent/PL104611B1/pl unknown
- 1977-10-16 IE IE2041/77A patent/IE45708B1/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: A/S APOTHEKERNES LABORATORIUM |