FI60555C - Foerfarande foer framstaellning av terapeutiskt anvaendbara aromatiska karboxylamidderivat - Google Patents
Foerfarande foer framstaellning av terapeutiskt anvaendbara aromatiska karboxylamidderivat Download PDFInfo
- Publication number
- FI60555C FI60555C FI145/74A FI14574A FI60555C FI 60555 C FI60555 C FI 60555C FI 145/74 A FI145/74 A FI 145/74A FI 14574 A FI14574 A FI 14574A FI 60555 C FI60555 C FI 60555C
- Authority
- FI
- Finland
- Prior art keywords
- formula
- acid
- cooh
- aromatic
- compound
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP735973A JPS5640710B2 (fr) | 1973-01-18 | 1973-01-18 | |
JP735973 | 1973-01-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
FI60555B FI60555B (fi) | 1981-10-30 |
FI60555C true FI60555C (fi) | 1982-02-10 |
Family
ID=11663750
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI145/74A FI60555C (fi) | 1973-01-18 | 1974-01-18 | Foerfarande foer framstaellning av terapeutiskt anvaendbara aromatiska karboxylamidderivat |
Country Status (18)
Country | Link |
---|---|
US (2) | US3940422A (fr) |
JP (1) | JPS5640710B2 (fr) |
AT (1) | AT333726B (fr) |
BE (1) | BE809935A (fr) |
BG (1) | BG24538A3 (fr) |
CH (2) | CH615152A5 (fr) |
DE (1) | DE2402398C3 (fr) |
DK (1) | DK139676C (fr) |
ES (1) | ES422395A1 (fr) |
FI (1) | FI60555C (fr) |
FR (1) | FR2214476B1 (fr) |
GB (1) | GB1446141A (fr) |
HU (1) | HU168055B (fr) |
IT (1) | IT1054151B (fr) |
NL (1) | NL179370C (fr) |
NO (1) | NO142441C (fr) |
SE (1) | SE411117B (fr) |
SU (1) | SU520041A3 (fr) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4144250A (en) * | 1973-05-14 | 1979-03-13 | Stauffer Chemical Company | Herbicidal active carboxanilide derivatives |
JPS5830302B2 (ja) * | 1974-04-16 | 1983-06-28 | キツセイヤクヒンコウギヨウ カブシキガイシヤ | シンキホウコウゾクカルボンサンアミドユウドウタイ ノ セイゾウホウホウ |
GB1484413A (en) * | 1974-04-18 | 1977-09-01 | Kissei Pharmaceutical | Aromatic amidocarboxylic acid derivatives |
DE2629752A1 (de) * | 1976-07-02 | 1978-01-05 | Boehringer Mannheim Gmbh | Neue carbonsaeurederivate und verfahren zu ihrer herstellung |
JPS56135454A (en) * | 1980-03-26 | 1981-10-22 | Kissei Pharmaceut Co Ltd | Preparation of aromatic carboxylic acid amide derivative |
US4337270A (en) * | 1980-05-21 | 1982-06-29 | Hisamitsu Pharmaceutical Co., Inc. | Novel anthranilic acid derivatives |
JPS5838244A (ja) * | 1981-09-01 | 1983-03-05 | Kissei Pharmaceut Co Ltd | 核置換シンナモイルアントラニル酸塩およびその製造方法 |
US4536346A (en) * | 1983-05-06 | 1985-08-20 | American Cyanamid Company | Aralkanamidophenyl compounds |
JPS6097946A (ja) * | 1983-11-01 | 1985-05-31 | Ono Pharmaceut Co Ltd | カルボキサミド誘導体 |
JPS60116657A (ja) * | 1983-11-30 | 1985-06-24 | Ono Pharmaceut Co Ltd | アニリン誘導体 |
JPS60142936A (ja) * | 1983-12-28 | 1985-07-29 | Ono Pharmaceut Co Ltd | 置換フエニル誘導体 |
JPS60146856A (ja) * | 1983-12-30 | 1985-08-02 | Kissei Pharmaceut Co Ltd | α−ハロ芳香族アミドカルボン酸誘導体及びこの化合物より成る抗アレルギ−剤 |
JPS60146857A (ja) * | 1983-12-30 | 1985-08-02 | Kissei Pharmaceut Co Ltd | α−ハロ芳香族アミドカルボン酸誘導体及びこの化合物より成る抗アレルギ−剤 |
IT1196348B (it) * | 1984-11-29 | 1988-11-16 | Italfarmaco Spa | Composti ad attivita'antiinfiammatoria |
JPH078851B2 (ja) * | 1985-07-29 | 1995-02-01 | 鐘淵化学工業株式会社 | 3−フエニルチオメチルスチレン誘導体 |
JPH0733357B2 (ja) * | 1986-09-30 | 1995-04-12 | 日本レダリ−株式会社 | ケイ皮酸誘導体 |
JPH0692353B2 (ja) * | 1987-05-26 | 1994-11-16 | マルコ製薬株式会社 | 新規なアミノ安息香酸アミド誘導体およびその製造法 |
JP2632732B2 (ja) * | 1989-11-06 | 1997-07-23 | 株式会社興人 | N―(3’,4’―ジメトキシシンナモイル)アントラニル酸の製造方法 |
US5811447A (en) * | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
JP2617407B2 (ja) * | 1992-09-14 | 1997-06-04 | キッセイ薬品工業株式会社 | 血管内膜細胞過剰増殖疾患の予防および治療剤 |
US5770609A (en) * | 1993-01-28 | 1998-06-23 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6395494B1 (en) * | 1993-05-13 | 2002-05-28 | Neorx Corporation | Method to determine TGF-β |
US6306421B1 (en) | 1992-09-25 | 2001-10-23 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5981568A (en) | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5595722A (en) * | 1993-01-28 | 1997-01-21 | Neorx Corporation | Method for identifying an agent which increases TGF-beta levels |
US6663881B2 (en) | 1993-01-28 | 2003-12-16 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
DE69435137D1 (de) * | 1993-05-13 | 2008-10-16 | Poniard Pharmaceuticals Inc | Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind |
US20030083733A1 (en) * | 1997-10-10 | 2003-05-01 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US20020091433A1 (en) * | 1995-04-19 | 2002-07-11 | Ni Ding | Drug release coated stent |
US5837313A (en) * | 1995-04-19 | 1998-11-17 | Schneider (Usa) Inc | Drug release stent coating process |
US6099562A (en) * | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
CA2223595C (fr) | 1995-06-07 | 2008-08-05 | Neorx Corporation | Prevention et traitement de pathologies cardio-vasculaires au moyen d'analogues de tamoxifene |
EP0887340A4 (fr) * | 1996-02-06 | 2000-03-29 | Japan Tobacco Inc | Composes chimiques et utilisation pharmaceutique |
US6019104A (en) * | 1996-12-30 | 2000-02-01 | Kissei Pharmaceutical Co., Ltd. | Method for the treatment or prevention of restenosis associated with coronary intervention |
DE19935219A1 (de) | 1999-07-27 | 2001-02-01 | Boehringer Ingelheim Pharma | Carbonsäureamide, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Herstellung |
DE10065043A1 (de) * | 2000-12-23 | 2002-07-04 | Boehringer Ingelheim Pharma | Carbonsäureamide, diese Verbindungen enthaltene Arzneimittel, deren Verwendung und Herstellung |
DE10065042A1 (de) * | 2000-12-23 | 2002-06-27 | Boehringer Ingelheim Pharma | Carbonsäureamide, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Herstellung |
US6613083B2 (en) * | 2001-05-02 | 2003-09-02 | Eckhard Alt | Stent device and method |
EP1318141A1 (fr) * | 2001-12-04 | 2003-06-11 | Dsm Nv | Traitement d'une phase aqueuse contenant des phosphates, du cyclohexanone et l'oxime correspondant |
BR0117189B1 (pt) * | 2001-12-04 | 2011-08-09 | processo para tratar um meio aquoso que contém oxima de ciclohexanona e ciclohexanona. | |
WO2003049702A2 (fr) * | 2001-12-10 | 2003-06-19 | Amgen Inc. | Ligands de recepteur vanilloide et utilisation de ceux-ci dans des traitements |
AU2003298567B9 (en) * | 2002-08-29 | 2009-07-23 | Temple University - Of The Commonwealth System Of Higher Education | Aryl and heteroaryl propene amides, derivatives thereof and therapeutic uses thereof |
DE10254872A1 (de) * | 2002-11-25 | 2004-06-03 | Symrise Gmbh & Co. Kg | Anthranilsäureamide und deren Derivate als kosmetische und pharmazeutische Wirkstoffe |
WO2005110392A1 (fr) * | 2004-05-14 | 2005-11-24 | The University Of Melbourne | Procedes de modulation de l'activite de flt3 |
CA2594460A1 (fr) | 2005-01-14 | 2006-07-20 | The Board Of Trustees Of The Leland Stanford Junior University | Procede pour moduler le fonctionnement de cellules t |
ITMI20050261A1 (it) * | 2005-02-21 | 2006-08-22 | Carlo Ghisalberti | Analoghi strutturali di avenatramidi loro uso in composizioni utili nel trattamento di disordini dermatologici |
EP1886662B1 (fr) * | 2006-06-14 | 2014-04-09 | Symrise AG | Compositions actives anti-microbiennes destinées au traitement de la mauvaise haleine |
ES2462925T3 (es) * | 2006-06-14 | 2014-05-26 | Symrise Ag | Compuestos con efecto antimicrobiano para el tratamiento de fetidez oral |
PL2035369T3 (pl) | 2006-07-05 | 2015-02-27 | Fibrotech Therapeutics Pty Ltd | Związki terapeutyczne |
WO2008131481A1 (fr) * | 2007-04-26 | 2008-11-06 | Fibrotech Therapeutics Pty Ltd | Traitement de maladies mésangioprolifératives |
JP5730578B2 (ja) * | 2007-12-21 | 2015-06-10 | フィブロテック セラピューティクス プロプライエタリー リミテッド | 抗線維症剤のハロゲン化類似体 |
US20100160351A1 (en) * | 2008-12-19 | 2010-06-24 | Nuon Therapeutics, Inc. | Pharmaceutical compositions and methods for treating hyperuricemia and related disorders |
WO2010071865A1 (fr) | 2008-12-19 | 2010-06-24 | Nuon Therapeutics, Inc. | Compositions pharmaceutiques et procédés de traitement de l'hyperuricémie et des troubles associés |
US20100158905A1 (en) | 2008-12-19 | 2010-06-24 | Nuon Therapeutics, Inc. | Combination therapy of arthritis with tranilast |
US9592213B2 (en) | 2009-06-17 | 2017-03-14 | National University Corporation Kumamoto University | Prophylactic and/or therapeutic agent for dysmenorrhea |
CN105153188B (zh) | 2009-10-22 | 2018-06-01 | 法博太科制药有限公司 | 抗纤维化剂的稠环类似物 |
DE102009046115A1 (de) * | 2009-10-28 | 2011-09-08 | Bayer Schering Pharma Aktiengesellschaft | Substituierte 3-Phenylpropansäuren und ihre Verwendung |
RU2556004C2 (ru) * | 2011-01-25 | 2015-07-10 | Мицуй Кемикалс Агро, Инк. | Способ получения производного ароматического амида карбоновой кислоты |
US10188754B2 (en) | 2013-05-16 | 2019-01-29 | The Johns Hopkins University | Compositions and methods for chemical exchange saturation transfer (CEST) based magnetic resonance imaging (MRI) |
CN104693063A (zh) * | 2015-03-18 | 2015-06-10 | 中国药科大学制药有限公司 | 一种曲尼司特的合成方法 |
MX2019009235A (es) | 2017-02-03 | 2019-12-11 | Certa Therapeutics Pty Ltd | Compuestos antifibroticos. |
CN110357789B (zh) * | 2018-04-11 | 2022-09-30 | 华东理工大学 | 作为dhodh抑制剂的n-取代丙烯酰胺衍生物及其制备和用途 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3043868A (en) * | 1959-12-09 | 1962-07-10 | Searle & Co | N-xenylalkanoylaminoalkanoic acids and esters thereof |
GB1074480A (en) * | 1964-07-29 | 1967-07-05 | Pfizer & Co C | Amino acid derivatives and method of preparation |
AT313463B (de) * | 1968-05-18 | 1974-02-25 | Rhodiaceta Ag | Verfahren und Vorrichtung zur Herstellung eines Wirrfadens |
-
1973
- 1973-01-18 JP JP735973A patent/JPS5640710B2/ja not_active Expired
-
1974
- 1974-01-16 GB GB210274A patent/GB1446141A/en not_active Expired
- 1974-01-17 HU HUKO701A patent/HU168055B/hu unknown
- 1974-01-17 SU SU1988815A patent/SU520041A3/ru active
- 1974-01-17 NO NO740137A patent/NO142441C/no unknown
- 1974-01-17 US US05/434,252 patent/US3940422A/en not_active Expired - Lifetime
- 1974-01-17 ES ES422395A patent/ES422395A1/es not_active Expired
- 1974-01-17 SE SE7400615A patent/SE411117B/xx not_active IP Right Cessation
- 1974-01-18 CH CH70474A patent/CH615152A5/de not_active IP Right Cessation
- 1974-01-18 NL NLAANVRAGE7400754,A patent/NL179370C/xx not_active IP Right Cessation
- 1974-01-18 DK DK27574A patent/DK139676C/da active
- 1974-01-18 FI FI145/74A patent/FI60555C/fi active
- 1974-01-18 AT AT44374*#A patent/AT333726B/de not_active IP Right Cessation
- 1974-01-18 DE DE2402398A patent/DE2402398C3/de not_active Expired
- 1974-01-18 BG BG7400025538A patent/BG24538A3/xx unknown
- 1974-01-18 CH CH198278A patent/CH613442A5/xx not_active IP Right Cessation
- 1974-01-18 FR FR7401823A patent/FR2214476B1/fr not_active Expired
- 1974-01-18 BE BE139980A patent/BE809935A/fr not_active IP Right Cessation
- 1974-07-07 IT IT19520/74A patent/IT1054151B/it active
-
1977
- 1977-06-01 US US05/802,486 patent/USRE32944E/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CH613442A5 (fr) | 1979-09-28 |
ES422395A1 (es) | 1976-08-01 |
SE411117B (sv) | 1979-12-03 |
NL179370B (nl) | 1986-04-01 |
NO740137L (no) | 1974-07-19 |
NO142441C (no) | 1980-08-20 |
DE2402398B2 (de) | 1980-10-09 |
NL7400754A (fr) | 1974-07-22 |
FI60555B (fi) | 1981-10-30 |
JPS5640710B2 (fr) | 1981-09-22 |
GB1446141A (en) | 1976-08-18 |
JPS4993335A (fr) | 1974-09-05 |
AT333726B (de) | 1976-12-10 |
BE809935A (fr) | 1974-05-16 |
FR2214476B1 (fr) | 1977-08-12 |
IT1054151B (it) | 1981-11-10 |
DK139676B (da) | 1979-03-26 |
DE2402398A1 (de) | 1974-08-08 |
DK139676C (da) | 1979-09-10 |
USRE32944E (en) | 1989-06-06 |
ATA44374A (de) | 1976-04-15 |
CH615152A5 (en) | 1980-01-15 |
AU6461374A (en) | 1975-07-17 |
DE2402398C3 (de) | 1981-07-23 |
US3940422A (en) | 1976-02-24 |
BG24538A3 (en) | 1978-03-10 |
SU520041A3 (ru) | 1976-06-30 |
NO142441B (no) | 1980-05-12 |
NL179370C (nl) | 1986-09-01 |
HU168055B (fr) | 1976-02-28 |
FR2214476A1 (fr) | 1974-08-19 |
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