FI59087C - Foerfarande foer framstaellning av 2,5-disubstituerade bensamider - Google Patents
Foerfarande foer framstaellning av 2,5-disubstituerade bensamider Download PDFInfo
- Publication number
- FI59087C FI59087C FI2762/74A FI276274A FI59087C FI 59087 C FI59087 C FI 59087C FI 2762/74 A FI2762/74 A FI 2762/74A FI 276274 A FI276274 A FI 276274A FI 59087 C FI59087 C FI 59087C
- Authority
- FI
- Finland
- Prior art keywords
- formula
- preparation
- disubstituerade
- bensamider
- foerfarande foer
- Prior art date
Links
- 238000000034 method Methods 0.000 claims description 19
- 238000002360 preparation method Methods 0.000 claims description 9
- DLYUQMMRRRQYAE-UHFFFAOYSA-N tetraphosphorus decaoxide Chemical compound O1P(O2)(=O)OP3(=O)OP1(=O)OP2(=O)O3 DLYUQMMRRRQYAE-UHFFFAOYSA-N 0.000 claims description 8
- 239000002253 acid Substances 0.000 claims description 5
- 229940054066 benzamide antipsychotics Drugs 0.000 claims description 4
- 150000003936 benzamides Chemical class 0.000 claims description 4
- 150000001875 compounds Chemical class 0.000 claims description 4
- 150000003242 quaternary ammonium salts Chemical class 0.000 claims description 4
- 150000003839 salts Chemical class 0.000 claims description 4
- 150000001412 amines Chemical class 0.000 claims description 3
- WPYMKLBDIGXBTP-UHFFFAOYSA-N Benzoic acid Natural products OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims description 2
- 239000005711 Benzoic acid Substances 0.000 claims description 2
- 125000000217 alkyl group Chemical group 0.000 claims description 2
- 235000010233 benzoic acid Nutrition 0.000 claims description 2
- 150000001558 benzoic acid derivatives Chemical class 0.000 claims description 2
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 claims description 2
- 125000004663 dialkyl amino group Chemical group 0.000 claims description 2
- 150000007522 mineralic acids Chemical class 0.000 claims description 2
- 125000000896 monocarboxylic acid group Chemical group 0.000 claims description 2
- 150000007524 organic acids Chemical class 0.000 claims description 2
- 235000005985 organic acids Nutrition 0.000 claims description 2
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- UNRHXEPDKXPRTM-UHFFFAOYSA-N Sultopride Chemical compound CCN1CCCC1CNC(=O)C1=CC(S(=O)(=O)CC)=CC=C1OC UNRHXEPDKXPRTM-UHFFFAOYSA-N 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- JTVPZMFULRWINT-UHFFFAOYSA-N N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide Chemical compound CCN(CC)CCNC(=O)C1=CC(S(C)(=O)=O)=CC=C1OC JTVPZMFULRWINT-UHFFFAOYSA-N 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 2
- 235000019341 magnesium sulphate Nutrition 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 239000012074 organic phase Substances 0.000 description 2
- SEYURSMOEWBZSA-UHFFFAOYSA-N 2-(1-ethylpyrrolidin-2-yl)ethanamine Chemical compound CCN1CCCC1CCN SEYURSMOEWBZSA-UHFFFAOYSA-N 0.000 description 1
- BXWLVQXAFBWKSR-UHFFFAOYSA-N 2-methoxy-5-methylsulfonylbenzoic acid Chemical compound COC1=CC=C(S(C)(=O)=O)C=C1C(O)=O BXWLVQXAFBWKSR-UHFFFAOYSA-N 0.000 description 1
- NBFYWQQYIJTQQV-UHFFFAOYSA-N 5-ethylsulfonyl-2-methoxybenzoic acid Chemical compound CCS(=O)(=O)C1=CC=C(OC)C(C(O)=O)=C1 NBFYWQQYIJTQQV-UHFFFAOYSA-N 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7335095 | 1973-09-28 | ||
| FR7335095A FR2245628B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-09-28 | 1973-09-28 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI276274A7 FI276274A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-03-29 |
| FI59087B FI59087B (fi) | 1981-02-27 |
| FI59087C true FI59087C (fi) | 1981-06-10 |
Family
ID=9125782
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI2762/74A FI59087C (fi) | 1973-09-28 | 1974-09-23 | Foerfarande foer framstaellning av 2,5-disubstituerade bensamider |
Country Status (11)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2418225A1 (fr) * | 1978-02-27 | 1979-09-21 | Synthelabo | Methoxy-2 benzamides et leur application en therapeutique |
| FR2418226A1 (fr) * | 1978-02-27 | 1979-09-21 | Synthelabo | Methoxy-2 alkylthio-5 benzamides et leur application en therapeutique |
| FR2447910A2 (fr) * | 1979-02-05 | 1980-08-29 | Synthelabo | Methoxy-2 alkylthio-5 benzamides et leur application en therapeutique |
| FR2478093A1 (fr) * | 1980-03-12 | 1981-09-18 | Ile De France | Nouveau procede de preparation de n-(1-alkyl (ou allyl) 2-pyrrolidinyl-methyl)2-methoxy (ou 2,3-dimethoxy) 5-sulfamoyl (ou sulfamoyl substitue) |
| AU2002364553A1 (en) * | 2001-12-28 | 2003-07-15 | Farmaceutsko-Hemijska Industrija "Zdravlje" | A process for synthesis of heterocyclic aminoalkyl benzamides |
-
1973
- 1973-09-28 FR FR7335095A patent/FR2245628B1/fr not_active Expired
-
1974
- 1974-01-01 AR AR255705A patent/AR205172A1/es active
- 1974-09-18 DE DE19742444587 patent/DE2444587A1/de not_active Withdrawn
- 1974-09-23 GB GB4131474A patent/GB1447329A/en not_active Expired
- 1974-09-23 CY CY974A patent/CY974A/xx unknown
- 1974-09-23 FI FI2762/74A patent/FI59087C/fi active
- 1974-09-24 ES ES430341A patent/ES430341A1/es not_active Expired
- 1974-09-24 CA CA209,914A patent/CA1055502A/en not_active Expired
- 1974-09-24 IE IE1971/74A patent/IE40402B1/xx unknown
- 1974-09-25 AT AT770474A patent/AT338235B/de not_active IP Right Cessation
- 1974-09-25 JP JP11039274A patent/JPS5715752B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1447329A (en) | 1976-08-25 |
| AR205172A1 (es) | 1976-04-12 |
| IE40402B1 (en) | 1979-05-23 |
| CY974A (en) | 1978-12-22 |
| AT338235B (de) | 1977-08-10 |
| JPS5059350A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-05-22 |
| ES430341A1 (es) | 1977-05-01 |
| CA1055502A (en) | 1979-05-29 |
| IE40402L (en) | 1975-03-28 |
| FR2245628A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-04-25 |
| ATA770474A (de) | 1976-12-15 |
| FI276274A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-03-29 |
| FR2245628B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-03-11 |
| FI59087B (fi) | 1981-02-27 |
| DE2444587A1 (de) | 1975-04-03 |
| JPS5715752B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1982-04-01 |
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